IL75583A - Derivatives of diphenylpyrazolyl-alkanoic(and alkenoic)acids,their preparation and pharmaceutical compositions containing them - Google Patents
Derivatives of diphenylpyrazolyl-alkanoic(and alkenoic)acids,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL75583A IL75583A IL75583A IL7558385A IL75583A IL 75583 A IL75583 A IL 75583A IL 75583 A IL75583 A IL 75583A IL 7558385 A IL7558385 A IL 7558385A IL 75583 A IL75583 A IL 75583A
- Authority
- IL
- Israel
- Prior art keywords
- 3alkyl
- phenoxy
- fluoro
- chloro
- diphenylpyrazolyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/382—Information transfer, e.g. on bus using universal interface adapter
- G06F13/387—Information transfer, e.g. on bus using universal interface adapter for adaptation of different data processing systems to different peripheral devices, e.g. protocol converters for incompatible systems, open system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/40—Bus structure
- G06F13/4004—Coupling between buses
- G06F13/4009—Coupling between buses with data restructuring
- G06F13/4018—Coupling between buses with data restructuring with data-width conversion
Landscapes
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62339384A | 1984-06-22 | 1984-06-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL75583A0 IL75583A0 (en) | 1985-10-31 |
IL75583A true IL75583A (en) | 1989-09-10 |
Family
ID=24497918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL75583A IL75583A (en) | 1984-06-22 | 1985-06-20 | Derivatives of diphenylpyrazolyl-alkanoic(and alkenoic)acids,their preparation and pharmaceutical compositions containing them |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0200736B1 (de) |
JP (1) | JPS61502467A (de) |
KR (1) | KR890001651B1 (de) |
AT (1) | ATE62906T1 (de) |
AU (1) | AU573368B2 (de) |
CA (1) | CA1249283A (de) |
DE (1) | DE3582674D1 (de) |
DK (1) | DK157543C (de) |
ES (1) | ES8703842A1 (de) |
FI (1) | FI860755A (de) |
GR (1) | GR851510B (de) |
HU (1) | HU198711B (de) |
IL (1) | IL75583A (de) |
MY (1) | MY101903A (de) |
NZ (1) | NZ212501A (de) |
PL (1) | PL151016B1 (de) |
PT (1) | PT80674B (de) |
WO (1) | WO1986000307A2 (de) |
ZA (1) | ZA854719B (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
EP0221025A1 (de) * | 1985-10-25 | 1987-05-06 | Sandoz Ag | Heterocyclische Analoga von Mevalonolacton und Derivate hiervon, Verfahren zu deren Herstellung sowie deren Verwendung als Pharmazeutika |
EP0244364A3 (de) * | 1986-04-30 | 1992-04-01 | Sandoz Ag | Herstellung von olefinischen Verbindungen |
US4808621A (en) * | 1986-07-07 | 1989-02-28 | Warner-Lambert Company | Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
IL83821A0 (en) * | 1986-09-10 | 1988-02-29 | Sandoz Ag | Azaindole and indolizine derivatives,their production and pharmaceutical compositions containing them |
US4751235A (en) * | 1986-12-23 | 1988-06-14 | Sandoz Pharm. Corp. | Anti-atherosclerotic indolizine derivatives |
US4735958A (en) * | 1986-12-22 | 1988-04-05 | Warner-Lambert Company | Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis |
US4898949A (en) * | 1987-02-25 | 1990-02-06 | Bristol-Myers Company | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
AT401518B (de) * | 1987-02-25 | 1996-09-25 | Bristol Myers Squibb Co | Neue tetrazol-verbindungen und verfahren zu ihrer herstellung |
US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
CA1336714C (en) * | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis |
US4997837A (en) * | 1987-09-08 | 1991-03-05 | Warner-Lambert Company | 6-(((substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
US4906624A (en) * | 1987-09-08 | 1990-03-06 | Warner-Lambert Company | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
US4822799A (en) * | 1988-01-27 | 1989-04-18 | Sandoz Pharm. Corp. | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals |
NO890522L (no) * | 1988-02-25 | 1989-08-28 | Bayer Ag | Substituerte imidazolinoner og imidazolinthioner. |
US5024999A (en) * | 1988-04-26 | 1991-06-18 | Nissan Chemical Industries Ltd. | Pyrazolopyridine type mevalonolactones useful as pharmaeuticals |
JP2890448B2 (ja) * | 1988-04-26 | 1999-05-17 | 日産化学工業株式会社 | ピラゾロピリジン系メバロノラクトン類 |
KR0162656B1 (ko) * | 1988-10-13 | 1999-01-15 | 로쓰 비엠, 하우스 한스-루돌프 | 7-치환된-헵트-6-엔산 및 -헵탄산과 그의 유도체 및 그의 중간체의 제조방법 |
JPH04270285A (ja) * | 1988-11-14 | 1992-09-25 | Nissan Chem Ind Ltd | ピラゾロピリミジン系メバロノラクトン類 |
IT1237793B (it) * | 1989-12-21 | 1993-06-17 | Zambon Spa | Composti attivi come inibitori dell'enzima hmg-coa reduttasi |
US5134155A (en) * | 1991-08-08 | 1992-07-28 | Ortho Pharmaceutical Corporation | Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors |
CA2118795A1 (en) * | 1991-09-20 | 1993-04-01 | John Crosby | Pyranones |
US5335293A (en) * | 1992-06-16 | 1994-08-02 | Key Technology, Inc. | Product inspection method and apparatus |
WO2004039365A1 (en) | 2002-11-01 | 2004-05-13 | Takeda Pharmaceutical Company Limited | Agent for preventing or treating neuropathy |
MX2007005137A (es) | 2004-11-23 | 2007-06-22 | Warner Lambert Co | Derivados del acido 7-(2h-pyrazol-3-il)-3, 5-dihidroxi-heptanoico como inhibidores de hmg co-a reductasa para el tratamiento de lipidemia. |
WO2006087630A2 (en) * | 2005-02-16 | 2006-08-24 | Warner-Lambert Company Llc | OXYPYRAZOLE HMG Co-A REDUCTASE INHIBITORS |
EP1775299A1 (de) * | 2005-10-05 | 2007-04-18 | LEK Pharmaceuticals D.D. | Verfahren zur Herstellung von HMG-CoA reduktase Inhibitoren |
WO2007081019A1 (ja) * | 2006-01-16 | 2007-07-19 | Sankyo Agro Company, Limited | (3-硫黄原子置換フェニル)ピラゾール誘導体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1261124B (de) * | 1961-09-22 | 1968-02-15 | Hoechst Ag | Verfahren zur Herstellung von Pyrazolen |
DE2920933A1 (de) * | 1979-05-23 | 1980-12-04 | Basf Ag | 3-aryl-5-methyl-pyrazol-4-carbonsaeureester enthaltende herbizide |
US4245106A (en) * | 1979-07-05 | 1981-01-13 | Monsanto Company | Process for the preparation of 1-alkyl-3-aryl-4-pyrazolecarboxylates |
-
1985
- 1985-06-18 HU HU853053A patent/HU198711B/hu not_active IP Right Cessation
- 1985-06-18 DE DE8585903248T patent/DE3582674D1/de not_active Expired - Lifetime
- 1985-06-18 AU AU45466/85A patent/AU573368B2/en not_active Ceased
- 1985-06-18 KR KR1019860700100A patent/KR890001651B1/ko not_active IP Right Cessation
- 1985-06-18 JP JP60502997A patent/JPS61502467A/ja active Pending
- 1985-06-18 WO PCT/EP1985/000293 patent/WO1986000307A2/en active IP Right Grant
- 1985-06-18 AT AT85903248T patent/ATE62906T1/de not_active IP Right Cessation
- 1985-06-18 EP EP85903248A patent/EP0200736B1/de not_active Expired - Lifetime
- 1985-06-20 PT PT80674A patent/PT80674B/pt not_active IP Right Cessation
- 1985-06-20 NZ NZ212501A patent/NZ212501A/xx unknown
- 1985-06-20 GR GR851510A patent/GR851510B/el unknown
- 1985-06-20 IL IL75583A patent/IL75583A/xx unknown
- 1985-06-21 ES ES544407A patent/ES8703842A1/es not_active Expired
- 1985-06-21 CA CA000484847A patent/CA1249283A/en not_active Expired
- 1985-06-21 ZA ZA854719A patent/ZA854719B/xx unknown
- 1985-06-21 PL PL1985254121A patent/PL151016B1/pl unknown
-
1986
- 1986-02-20 FI FI860755A patent/FI860755A/fi not_active Application Discontinuation
- 1986-02-21 DK DK083886A patent/DK157543C/da not_active IP Right Cessation
-
1987
- 1987-09-26 MY MYPI87001978A patent/MY101903A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ATE62906T1 (de) | 1991-05-15 |
PL151016B1 (en) | 1990-07-31 |
DK83886D0 (da) | 1986-02-21 |
HU198711B (en) | 1989-11-28 |
IL75583A0 (en) | 1985-10-31 |
GR851510B (de) | 1985-11-25 |
DK83886A (da) | 1986-02-21 |
DK157543C (da) | 1990-06-11 |
ES544407A0 (es) | 1987-03-01 |
AU4546685A (en) | 1986-01-24 |
PL254121A1 (en) | 1988-07-21 |
KR890001651B1 (ko) | 1989-05-12 |
HUT39178A (en) | 1986-08-28 |
CA1249283A (en) | 1989-01-24 |
EP0200736B1 (de) | 1991-04-24 |
FI860755A0 (fi) | 1986-02-20 |
EP0200736A1 (de) | 1986-11-12 |
DE3582674D1 (de) | 1991-05-29 |
AU573368B2 (en) | 1988-06-02 |
ZA854719B (en) | 1987-02-25 |
PT80674B (en) | 1987-03-17 |
WO1986000307A3 (en) | 1986-04-10 |
PT80674A (en) | 1985-07-01 |
DK157543B (da) | 1990-01-22 |
JPS61502467A (ja) | 1986-10-30 |
WO1986000307A2 (en) | 1986-01-16 |
NZ212501A (en) | 1988-06-30 |
ES8703842A1 (es) | 1987-03-01 |
KR860700253A (ko) | 1986-08-01 |
FI860755A (fi) | 1986-02-20 |
MY101903A (en) | 1992-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL75583A (en) | Derivatives of diphenylpyrazolyl-alkanoic(and alkenoic)acids,their preparation and pharmaceutical compositions containing them | |
NZ214402A (en) | Indene derivatives and pharmaceutical compositions | |
FI842615A (fi) | Analoger av mevalolakton och deras de- rivat, foerfarande foer producering av dessa, dessa innehaollande farmaceutiska kompositioner och deras anvaendning. | |
WO1987002662A3 (en) | Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals | |
IL76521A (en) | 3-amino-2-benzoylacrylic acid derivatives and their preparation | |
MY105158A (en) | Substituted 4-aminoquinoline derivatives as gastric acid secretion inhibutors. | |
PT77996B (en) | Process of the preparations of mevalonelactone analogs and derivatives thereof and of pharmaceutical compositions containing them | |
EP0228845A3 (en) | N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same | |
DE3362504D1 (en) | 1-carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use | |
SE7908940L (sv) | Nya acyl-1h-1,2,4-triazolderivat | |
ES8300709A1 (es) | Un metodo para la preparacion de derivados de pirazolidinona | |
IL76936A (en) | 3-amino-2,3-dihydro-1-benzoxepine compounds,their preparation and pharmaceutical compositions containing them |