IL75583A - Derivatives of diphenylpyrazolyl-alkanoic(and alkenoic)acids,their preparation and pharmaceutical compositions containing them - Google Patents
Derivatives of diphenylpyrazolyl-alkanoic(and alkenoic)acids,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL75583A IL75583A IL75583A IL7558385A IL75583A IL 75583 A IL75583 A IL 75583A IL 75583 A IL75583 A IL 75583A IL 7558385 A IL7558385 A IL 7558385A IL 75583 A IL75583 A IL 75583A
- Authority
- IL
- Israel
- Prior art keywords
- 3alkyl
- phenoxy
- fluoro
- chloro
- diphenylpyrazolyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/382—Information transfer, e.g. on bus using universal interface adapter
- G06F13/387—Information transfer, e.g. on bus using universal interface adapter for adaptation of different data processing systems to different peripheral devices, e.g. protocol converters for incompatible systems, open system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/40—Bus structure
- G06F13/4004—Coupling between buses
- G06F13/4009—Coupling between buses with data restructuring
- G06F13/4018—Coupling between buses with data restructuring with data-width conversion
Landscapes
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62339384A | 1984-06-22 | 1984-06-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL75583A0 IL75583A0 (en) | 1985-10-31 |
IL75583A true IL75583A (en) | 1989-09-10 |
Family
ID=24497918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL75583A IL75583A (en) | 1984-06-22 | 1985-06-20 | Derivatives of diphenylpyrazolyl-alkanoic(and alkenoic)acids,their preparation and pharmaceutical compositions containing them |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0200736B1 (xx) |
JP (1) | JPS61502467A (xx) |
KR (1) | KR890001651B1 (xx) |
AT (1) | ATE62906T1 (xx) |
AU (1) | AU573368B2 (xx) |
CA (1) | CA1249283A (xx) |
DE (1) | DE3582674D1 (xx) |
DK (1) | DK157543C (xx) |
ES (1) | ES8703842A1 (xx) |
FI (1) | FI860755A (xx) |
GR (1) | GR851510B (xx) |
HU (1) | HU198711B (xx) |
IL (1) | IL75583A (xx) |
MY (1) | MY101903A (xx) |
NZ (1) | NZ212501A (xx) |
PL (1) | PL151016B1 (xx) |
PT (1) | PT80674B (xx) |
WO (1) | WO1986000307A2 (xx) |
ZA (1) | ZA854719B (xx) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
HUT48208A (en) * | 1985-10-25 | 1989-05-29 | Sandoz Ag | Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds |
EP0244364A3 (en) * | 1986-04-30 | 1992-04-01 | Sandoz Ag | Preparation of olefinic compounds |
US4808621A (en) * | 1986-07-07 | 1989-02-28 | Warner-Lambert Company | Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
US4751235A (en) * | 1986-12-23 | 1988-06-14 | Sandoz Pharm. Corp. | Anti-atherosclerotic indolizine derivatives |
PT85662B (pt) * | 1986-09-10 | 1990-06-29 | Sandoz Sa | Processo para a preparacao de derivados de aza-indol e de indolizina e de composicoes farmaceuticas que os contem |
US4735958A (en) * | 1986-12-22 | 1988-04-05 | Warner-Lambert Company | Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis |
US4898949A (en) * | 1987-02-25 | 1990-02-06 | Bristol-Myers Company | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
AT401518B (de) * | 1987-02-25 | 1996-09-25 | Bristol Myers Squibb Co | Neue tetrazol-verbindungen und verfahren zu ihrer herstellung |
US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
CA1336714C (en) * | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis |
JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
US4906624A (en) * | 1987-09-08 | 1990-03-06 | Warner-Lambert Company | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
US4997837A (en) * | 1987-09-08 | 1991-03-05 | Warner-Lambert Company | 6-(((substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
US4822799A (en) * | 1988-01-27 | 1989-04-18 | Sandoz Pharm. Corp. | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals |
NO890522L (no) * | 1988-02-25 | 1989-08-28 | Bayer Ag | Substituerte imidazolinoner og imidazolinthioner. |
JP2890448B2 (ja) * | 1988-04-26 | 1999-05-17 | 日産化学工業株式会社 | ピラゾロピリジン系メバロノラクトン類 |
US5024999A (en) * | 1988-04-26 | 1991-06-18 | Nissan Chemical Industries Ltd. | Pyrazolopyridine type mevalonolactones useful as pharmaeuticals |
EP0562643A3 (en) * | 1988-10-13 | 1994-05-18 | Sandoz Ag | 7-substituted-hept-6-enoic and -heptanoic acids and derivatives thereof |
JPH04270285A (ja) * | 1988-11-14 | 1992-09-25 | Nissan Chem Ind Ltd | ピラゾロピリミジン系メバロノラクトン類 |
IT1237793B (it) * | 1989-12-21 | 1993-06-17 | Zambon Spa | Composti attivi come inibitori dell'enzima hmg-coa reduttasi |
US5134155A (en) * | 1991-08-08 | 1992-07-28 | Ortho Pharmaceutical Corporation | Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors |
CA2118795A1 (en) * | 1991-09-20 | 1993-04-01 | John Crosby | Pyranones |
US5335293A (en) * | 1992-06-16 | 1994-08-02 | Key Technology, Inc. | Product inspection method and apparatus |
WO2004039365A1 (en) | 2002-11-01 | 2004-05-13 | Takeda Pharmaceutical Company Limited | Agent for preventing or treating neuropathy |
KR20070084455A (ko) | 2004-11-23 | 2007-08-24 | 워너-램버트 캄파니 엘엘씨 | 지질혈증 치료용 hmg co-a 환원효소 억제제로서의7-(2h-피라졸-3-일)-3,5-디히드록시-헵탄산 유도체 |
WO2006087630A2 (en) * | 2005-02-16 | 2006-08-24 | Warner-Lambert Company Llc | OXYPYRAZOLE HMG Co-A REDUCTASE INHIBITORS |
EP1775299A1 (en) * | 2005-10-05 | 2007-04-18 | LEK Pharmaceuticals D.D. | Process for the synthesis of HMG-CoA reductase inhibitors |
TW200736225A (en) * | 2006-01-16 | 2007-10-01 | Sankyo Agro Co Ltd | A (3-sulfur substituted phenyl) pyrazole derivative |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1261124B (de) * | 1961-09-22 | 1968-02-15 | Hoechst Ag | Verfahren zur Herstellung von Pyrazolen |
DE2920933A1 (de) * | 1979-05-23 | 1980-12-04 | Basf Ag | 3-aryl-5-methyl-pyrazol-4-carbonsaeureester enthaltende herbizide |
US4245106A (en) * | 1979-07-05 | 1981-01-13 | Monsanto Company | Process for the preparation of 1-alkyl-3-aryl-4-pyrazolecarboxylates |
-
1985
- 1985-06-18 JP JP60502997A patent/JPS61502467A/ja active Pending
- 1985-06-18 EP EP85903248A patent/EP0200736B1/en not_active Expired - Lifetime
- 1985-06-18 HU HU853053A patent/HU198711B/hu not_active IP Right Cessation
- 1985-06-18 AT AT85903248T patent/ATE62906T1/de not_active IP Right Cessation
- 1985-06-18 AU AU45466/85A patent/AU573368B2/en not_active Ceased
- 1985-06-18 KR KR1019860700100A patent/KR890001651B1/ko not_active IP Right Cessation
- 1985-06-18 WO PCT/EP1985/000293 patent/WO1986000307A2/en active IP Right Grant
- 1985-06-18 DE DE8585903248T patent/DE3582674D1/de not_active Expired - Lifetime
- 1985-06-20 IL IL75583A patent/IL75583A/xx unknown
- 1985-06-20 GR GR851510A patent/GR851510B/el unknown
- 1985-06-20 PT PT80674A patent/PT80674B/pt not_active IP Right Cessation
- 1985-06-20 NZ NZ212501A patent/NZ212501A/xx unknown
- 1985-06-21 CA CA000484847A patent/CA1249283A/en not_active Expired
- 1985-06-21 PL PL1985254121A patent/PL151016B1/pl unknown
- 1985-06-21 ZA ZA854719A patent/ZA854719B/xx unknown
- 1985-06-21 ES ES544407A patent/ES8703842A1/es not_active Expired
-
1986
- 1986-02-20 FI FI860755A patent/FI860755A/fi not_active Application Discontinuation
- 1986-02-21 DK DK083886A patent/DK157543C/da not_active IP Right Cessation
-
1987
- 1987-09-26 MY MYPI87001978A patent/MY101903A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DK157543B (da) | 1990-01-22 |
KR860700253A (ko) | 1986-08-01 |
DK83886D0 (da) | 1986-02-21 |
EP0200736A1 (en) | 1986-11-12 |
AU573368B2 (en) | 1988-06-02 |
JPS61502467A (ja) | 1986-10-30 |
NZ212501A (en) | 1988-06-30 |
CA1249283A (en) | 1989-01-24 |
GR851510B (xx) | 1985-11-25 |
DK157543C (da) | 1990-06-11 |
FI860755A0 (fi) | 1986-02-20 |
IL75583A0 (en) | 1985-10-31 |
DK83886A (da) | 1986-02-21 |
MY101903A (en) | 1992-02-15 |
EP0200736B1 (en) | 1991-04-24 |
PL254121A1 (en) | 1988-07-21 |
ES544407A0 (es) | 1987-03-01 |
DE3582674D1 (de) | 1991-05-29 |
KR890001651B1 (ko) | 1989-05-12 |
ES8703842A1 (es) | 1987-03-01 |
PT80674B (en) | 1987-03-17 |
HU198711B (en) | 1989-11-28 |
PL151016B1 (en) | 1990-07-31 |
WO1986000307A2 (en) | 1986-01-16 |
ZA854719B (en) | 1987-02-25 |
PT80674A (en) | 1985-07-01 |
HUT39178A (en) | 1986-08-28 |
ATE62906T1 (de) | 1991-05-15 |
WO1986000307A3 (en) | 1986-04-10 |
FI860755A (fi) | 1986-02-20 |
AU4546685A (en) | 1986-01-24 |
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