ES544407A0 - Procedimiento para preparar derivados de menalonolactona. - Google Patents
Procedimiento para preparar derivados de menalonolactona.Info
- Publication number
- ES544407A0 ES544407A0 ES544407A ES544407A ES544407A0 ES 544407 A0 ES544407 A0 ES 544407A0 ES 544407 A ES544407 A ES 544407A ES 544407 A ES544407 A ES 544407A ES 544407 A0 ES544407 A0 ES 544407A0
- Authority
- ES
- Spain
- Prior art keywords
- 3alkyl
- phenoxy
- fluoro
- chloro
- trifluoromethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/382—Information transfer, e.g. on bus using universal interface adapter
- G06F13/387—Information transfer, e.g. on bus using universal interface adapter for adaptation of different data processing systems to different peripheral devices, e.g. protocol converters for incompatible systems, open system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/40—Bus structure
- G06F13/4004—Coupling between buses
- G06F13/4009—Coupling between buses with data restructuring
- G06F13/4018—Coupling between buses with data restructuring with data-width conversion
Landscapes
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62339384A | 1984-06-22 | 1984-06-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8703842A1 ES8703842A1 (es) | 1987-03-01 |
ES544407A0 true ES544407A0 (es) | 1987-03-01 |
Family
ID=24497918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544407A Expired ES8703842A1 (es) | 1984-06-22 | 1985-06-21 | Procedimiento para preparar derivados de menalonolactona. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0200736B1 (es) |
JP (1) | JPS61502467A (es) |
KR (1) | KR890001651B1 (es) |
AT (1) | ATE62906T1 (es) |
AU (1) | AU573368B2 (es) |
CA (1) | CA1249283A (es) |
DE (1) | DE3582674D1 (es) |
DK (1) | DK157543C (es) |
ES (1) | ES8703842A1 (es) |
FI (1) | FI860755A (es) |
GR (1) | GR851510B (es) |
HU (1) | HU198711B (es) |
IL (1) | IL75583A (es) |
MY (1) | MY101903A (es) |
NZ (1) | NZ212501A (es) |
PL (1) | PL151016B1 (es) |
PT (1) | PT80674B (es) |
WO (1) | WO1986000307A2 (es) |
ZA (1) | ZA854719B (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
KR900001212B1 (ko) * | 1985-10-25 | 1990-02-28 | 산도즈 파마슈티칼스 코오포레이숀 | 메바로노락톤 및 그것의 유도체의 헤테로사이클릭 유사체 및 그것의 생산방법 및 약학적인 그것의 용도 |
EP0244364A3 (en) * | 1986-04-30 | 1992-04-01 | Sandoz Ag | Preparation of olefinic compounds |
US4808621A (en) * | 1986-07-07 | 1989-02-28 | Warner-Lambert Company | Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
US4751235A (en) * | 1986-12-23 | 1988-06-14 | Sandoz Pharm. Corp. | Anti-atherosclerotic indolizine derivatives |
NZ221717A (en) * | 1986-09-10 | 1990-08-28 | Sandoz Ltd | Azaindole and indolizine derivatives and pharmaceutical compositions |
US4735958A (en) * | 1986-12-22 | 1988-04-05 | Warner-Lambert Company | Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis |
US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
US4898949A (en) * | 1987-02-25 | 1990-02-06 | Bristol-Myers Company | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
AT401518B (de) * | 1987-02-25 | 1996-09-25 | Bristol Myers Squibb Co | Neue tetrazol-verbindungen und verfahren zu ihrer herstellung |
CA1336714C (en) * | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis |
JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
US4906624A (en) * | 1987-09-08 | 1990-03-06 | Warner-Lambert Company | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
US4997837A (en) * | 1987-09-08 | 1991-03-05 | Warner-Lambert Company | 6-(((substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
US4822799A (en) * | 1988-01-27 | 1989-04-18 | Sandoz Pharm. Corp. | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals |
NO890522L (no) * | 1988-02-25 | 1989-08-28 | Bayer Ag | Substituerte imidazolinoner og imidazolinthioner. |
US5024999A (en) * | 1988-04-26 | 1991-06-18 | Nissan Chemical Industries Ltd. | Pyrazolopyridine type mevalonolactones useful as pharmaeuticals |
JP2890448B2 (ja) * | 1988-04-26 | 1999-05-17 | 日産化学工業株式会社 | ピラゾロピリジン系メバロノラクトン類 |
MY105067A (en) * | 1988-10-13 | 1994-07-30 | Novartis Ag | Process for the preparation of 7-substituted-hept-6-enoic and -heptanoic acids and derivatives and intermediates thereof. |
JPH04270285A (ja) * | 1988-11-14 | 1992-09-25 | Nissan Chem Ind Ltd | ピラゾロピリミジン系メバロノラクトン類 |
IT1237793B (it) * | 1989-12-21 | 1993-06-17 | Zambon Spa | Composti attivi come inibitori dell'enzima hmg-coa reduttasi |
US5134155A (en) * | 1991-08-08 | 1992-07-28 | Ortho Pharmaceutical Corporation | Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors |
CA2118795A1 (en) * | 1991-09-20 | 1993-04-01 | John Crosby | Pyranones |
US5335293A (en) * | 1992-06-16 | 1994-08-02 | Key Technology, Inc. | Product inspection method and apparatus |
PE20040609A1 (es) | 2002-11-01 | 2004-10-29 | Takeda Pharmaceutical | Compuestos heterociclicos aromaticos como promotores de un factor neurotrofico |
AP2007003979A0 (en) | 2004-11-23 | 2007-06-30 | Warner Lambert Co | 7-(2h-pyrazol-3-yl)-3,5-dihyroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for thetreatment of lipidemia |
WO2006087630A2 (en) * | 2005-02-16 | 2006-08-24 | Warner-Lambert Company Llc | OXYPYRAZOLE HMG Co-A REDUCTASE INHIBITORS |
EP1775299A1 (en) * | 2005-10-05 | 2007-04-18 | LEK Pharmaceuticals D.D. | Process for the synthesis of HMG-CoA reductase inhibitors |
WO2007081019A1 (ja) * | 2006-01-16 | 2007-07-19 | Sankyo Agro Company, Limited | (3-硫黄原子置換フェニル)ピラゾール誘導体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1261124B (de) * | 1961-09-22 | 1968-02-15 | Hoechst Ag | Verfahren zur Herstellung von Pyrazolen |
DE2920933A1 (de) * | 1979-05-23 | 1980-12-04 | Basf Ag | 3-aryl-5-methyl-pyrazol-4-carbonsaeureester enthaltende herbizide |
US4245106A (en) * | 1979-07-05 | 1981-01-13 | Monsanto Company | Process for the preparation of 1-alkyl-3-aryl-4-pyrazolecarboxylates |
-
1985
- 1985-06-18 KR KR1019860700100A patent/KR890001651B1/ko not_active IP Right Cessation
- 1985-06-18 HU HU853053A patent/HU198711B/hu not_active IP Right Cessation
- 1985-06-18 EP EP85903248A patent/EP0200736B1/en not_active Expired - Lifetime
- 1985-06-18 AU AU45466/85A patent/AU573368B2/en not_active Ceased
- 1985-06-18 WO PCT/EP1985/000293 patent/WO1986000307A2/en active IP Right Grant
- 1985-06-18 JP JP60502997A patent/JPS61502467A/ja active Pending
- 1985-06-18 DE DE8585903248T patent/DE3582674D1/de not_active Expired - Lifetime
- 1985-06-18 AT AT85903248T patent/ATE62906T1/de not_active IP Right Cessation
- 1985-06-20 PT PT80674A patent/PT80674B/pt not_active IP Right Cessation
- 1985-06-20 IL IL75583A patent/IL75583A/xx unknown
- 1985-06-20 GR GR851510A patent/GR851510B/el unknown
- 1985-06-20 NZ NZ212501A patent/NZ212501A/xx unknown
- 1985-06-21 ES ES544407A patent/ES8703842A1/es not_active Expired
- 1985-06-21 PL PL1985254121A patent/PL151016B1/pl unknown
- 1985-06-21 CA CA000484847A patent/CA1249283A/en not_active Expired
- 1985-06-21 ZA ZA854719A patent/ZA854719B/xx unknown
-
1986
- 1986-02-20 FI FI860755A patent/FI860755A/fi not_active Application Discontinuation
- 1986-02-21 DK DK083886A patent/DK157543C/da not_active IP Right Cessation
-
1987
- 1987-09-26 MY MYPI87001978A patent/MY101903A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA1249283A (en) | 1989-01-24 |
DK157543C (da) | 1990-06-11 |
FI860755A0 (fi) | 1986-02-20 |
PL254121A1 (en) | 1988-07-21 |
EP0200736B1 (en) | 1991-04-24 |
WO1986000307A3 (en) | 1986-04-10 |
ZA854719B (en) | 1987-02-25 |
ES8703842A1 (es) | 1987-03-01 |
EP0200736A1 (en) | 1986-11-12 |
DE3582674D1 (de) | 1991-05-29 |
HUT39178A (en) | 1986-08-28 |
NZ212501A (en) | 1988-06-30 |
JPS61502467A (ja) | 1986-10-30 |
AU4546685A (en) | 1986-01-24 |
ATE62906T1 (de) | 1991-05-15 |
DK157543B (da) | 1990-01-22 |
PL151016B1 (en) | 1990-07-31 |
HU198711B (en) | 1989-11-28 |
FI860755A (fi) | 1986-02-20 |
MY101903A (en) | 1992-02-15 |
IL75583A0 (en) | 1985-10-31 |
AU573368B2 (en) | 1988-06-02 |
GR851510B (es) | 1985-11-25 |
KR860700253A (ko) | 1986-08-01 |
IL75583A (en) | 1989-09-10 |
DK83886A (da) | 1986-02-21 |
KR890001651B1 (ko) | 1989-05-12 |
WO1986000307A2 (en) | 1986-01-16 |
PT80674A (en) | 1985-07-01 |
PT80674B (en) | 1987-03-17 |
DK83886D0 (da) | 1986-02-21 |
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