IL70880A - N-methyl-s-methyl-n'(2-(2-dimethylaminomethylthiazol-4-ylmethylthio)ethyl)-isothiourea,its preparation and use in the preparation of nizatidine - Google Patents

N-methyl-s-methyl-n'(2-(2-dimethylaminomethylthiazol-4-ylmethylthio)ethyl)-isothiourea,its preparation and use in the preparation of nizatidine

Info

Publication number
IL70880A
IL70880A IL70880A IL7088084A IL70880A IL 70880 A IL70880 A IL 70880A IL 70880 A IL70880 A IL 70880A IL 7088084 A IL7088084 A IL 7088084A IL 70880 A IL70880 A IL 70880A
Authority
IL
Israel
Prior art keywords
methyl
preparation
ylmethylthio
isothiourea
nizatidine
Prior art date
Application number
IL70880A
Other languages
English (en)
Other versions
IL70880A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23843341&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL70880(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL70880A0 publication Critical patent/IL70880A0/xx
Publication of IL70880A publication Critical patent/IL70880A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
IL70880A 1983-02-07 1984-02-06 N-methyl-s-methyl-n'(2-(2-dimethylaminomethylthiazol-4-ylmethylthio)ethyl)-isothiourea,its preparation and use in the preparation of nizatidine IL70880A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46429683A 1983-02-07 1983-02-07

Publications (2)

Publication Number Publication Date
IL70880A0 IL70880A0 (en) 1984-05-31
IL70880A true IL70880A (en) 1987-01-30

Family

ID=23843341

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70880A IL70880A (en) 1983-02-07 1984-02-06 N-methyl-s-methyl-n'(2-(2-dimethylaminomethylthiazol-4-ylmethylthio)ethyl)-isothiourea,its preparation and use in the preparation of nizatidine

Country Status (27)

Country Link
EP (1) EP0116452B1 (ja)
JP (1) JPS59152378A (ja)
KR (1) KR860000767B1 (ja)
AT (1) ATE84530T1 (ja)
AU (1) AU559639B2 (ja)
BG (1) BG45216A3 (ja)
CA (1) CA1221369A (ja)
CS (1) CS240994B2 (ja)
DD (1) DD216459A5 (ja)
DE (1) DE3486032T2 (ja)
DK (2) DK164501C (ja)
EG (1) EG17702A (ja)
ES (1) ES8601941A1 (ja)
FI (1) FI840474A (ja)
GB (1) GB2134521B (ja)
GR (1) GR81755B (ja)
HU (2) HU190527B (ja)
IE (1) IE56763B1 (ja)
IL (1) IL70880A (ja)
NZ (1) NZ207046A (ja)
PH (1) PH19941A (ja)
PL (1) PL138793B1 (ja)
PT (1) PT78063A (ja)
RO (1) RO87706A (ja)
SU (1) SU1303028A3 (ja)
UA (1) UA6020A1 (ja)
ZA (1) ZA84869B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230127A1 (en) * 1985-12-18 1987-07-29 Eli Lilly And Company Synthesis of nizatidine
ES2038922B1 (es) * 1991-12-30 1994-04-16 Fermentaciones Y Sintesis Espa Procedimiento para la obtencion de nizatidina.
US5470865A (en) * 1994-08-30 1995-11-28 Eli Lilly And Company Pharmaceutical composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
HU194198B (en) 1988-01-28
CS240994B2 (en) 1986-03-13
RO87706B (ro) 1985-10-01
CS81284A2 (en) 1985-06-13
ATE84530T1 (de) 1993-01-15
NZ207046A (en) 1986-06-11
PT78063A (en) 1984-03-01
ES529492A0 (es) 1985-11-01
PL138793B1 (en) 1986-11-29
DD216459A5 (de) 1984-12-12
DK21292A (da) 1992-02-19
AU559639B2 (en) 1987-03-19
EP0116452A3 (en) 1987-04-29
JPH0576473B2 (ja) 1993-10-22
DK51984A (da) 1984-08-08
DK164501C (da) 1992-11-23
SU1303028A3 (ru) 1987-04-07
EP0116452A2 (en) 1984-08-22
KR840007591A (ko) 1984-12-08
DK51984D0 (da) 1984-02-06
PH19941A (en) 1986-08-14
GB2134521B (en) 1986-10-01
DE3486032T2 (de) 1993-05-19
FI840474A0 (fi) 1984-02-06
EP0116452B1 (en) 1993-01-13
DE3486032D1 (de) 1993-02-25
AU2421584A (en) 1984-08-16
KR860000767B1 (ko) 1986-06-23
ZA84869B (en) 1985-09-25
GB8403109D0 (en) 1984-03-07
IE840274L (en) 1984-08-07
GR81755B (ja) 1984-12-12
HU190527B (en) 1986-09-29
UA6020A1 (uk) 1994-12-29
BG45216A3 (ja) 1989-04-14
FI840474A (fi) 1984-08-08
CA1221369A (en) 1987-05-05
DK164501B (da) 1992-07-06
DK164906B (da) 1992-09-07
DK164906C (da) 1993-01-25
JPS59152378A (ja) 1984-08-31
IL70880A0 (en) 1984-05-31
GB2134521A (en) 1984-08-15
RO87706A (ro) 1985-10-31
ES8601941A1 (es) 1985-11-01
DK21292D0 (da) 1992-02-19
IE56763B1 (en) 1991-12-04
EG17702A (en) 1991-03-30
PL246097A1 (en) 1985-06-04

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Legal Events

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KB Patent renewed
EXP Patent expired