IL66921A0 - Processes for preparing piroxicam and intermediates used therein - Google Patents

Processes for preparing piroxicam and intermediates used therein

Info

Publication number
IL66921A0
IL66921A0 IL66921A IL6692182A IL66921A0 IL 66921 A0 IL66921 A0 IL 66921A0 IL 66921 A IL66921 A IL 66921A IL 6692182 A IL6692182 A IL 6692182A IL 66921 A0 IL66921 A0 IL 66921A0
Authority
IL
Israel
Prior art keywords
piroxicam
alkyl
processes
hydroxy
methyl
Prior art date
Application number
IL66921A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/308,746 external-priority patent/US4376204A/en
Application filed by Pfizer filed Critical Pfizer
Priority to IL7638982A priority Critical patent/IL76389A/xx
Publication of IL66921A0 publication Critical patent/IL66921A0/xx
Priority to IL76389A priority patent/IL76389A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/041,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/081,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/021,2-Thiazines; Hydrogenated 1,2-thiazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
IL66921A 1981-10-05 1982-09-30 Processes for preparing piroxicam and intermediates used therein IL66921A0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL7638982A IL76389A (en) 1981-10-05 1982-09-30 Preparation of esters of 2h-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide useful as intermediates for preparing piroxicam and certain novel 2-(2-methyl-3-hydroxy-2-3-dihydro-1,2-benzisoxazol-3-yl)-2-haloacetates used as starting materials therefor
IL76389A IL76389A0 (en) 1981-10-05 1985-09-13 Preparation of esters of 2h-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide useful as intermediates for preparing piroxicam and certain novel 2-(2-methyl-3-hydroxy-2,3-dihydro-1,2-benzisosulfonazol-3-yl)-2-haloacetates used as starting materials therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/308,746 US4376204A (en) 1981-10-05 1981-10-05 3-Hydroxy 2-methyl benzisothiazolines as intermediates in production of piroxicam
US41303682A 1982-09-02 1982-09-02

Publications (1)

Publication Number Publication Date
IL66921A0 true IL66921A0 (en) 1982-12-31

Family

ID=26976430

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66921A IL66921A0 (en) 1981-10-05 1982-09-30 Processes for preparing piroxicam and intermediates used therein

Country Status (27)

Country Link
EP (1) EP0076643B1 (es)
KR (1) KR850001223B1 (es)
AT (1) ATE11916T1 (es)
AU (1) AU534759B2 (es)
BG (2) BG40811A3 (es)
CA (1) CA1187873A (es)
DD (2) DD216460A5 (es)
DE (1) DE3262440D1 (es)
DK (2) DK154646C (es)
EG (1) EG15847A (es)
ES (2) ES516208A0 (es)
FI (1) FI75342C (es)
GR (1) GR77345B (es)
HK (1) HK52687A (es)
HU (1) HU186977B (es)
IE (1) IE53957B1 (es)
IL (1) IL66921A0 (es)
IN (1) IN159273B (es)
MY (1) MY8700510A (es)
NO (1) NO157140C (es)
NZ (1) NZ202062A (es)
PH (2) PH17991A (es)
PL (2) PL136931B1 (es)
PT (1) PT75642B (es)
RO (2) RO86733B (es)
SG (1) SG22987G (es)
YU (2) YU42804B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU759169B2 (en) 1997-09-05 2003-04-10 Warner-Lambert Company Certain benzothiazine dioxide endothelin antagonists and processes for their preparation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
US3853862A (en) * 1973-04-23 1974-12-10 Pfizer Production of 4-hydroxy-1,2-benzothiazine-3-carboxamides
US3891637A (en) * 1974-10-01 1975-06-24 Pfizer Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides
US3892740A (en) * 1974-10-15 1975-07-01 Pfizer Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides
US3960856A (en) * 1975-06-20 1976-06-01 Warner-Lambert Company Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide
SE421792B (sv) * 1976-01-12 1982-02-01 Pfizer Forfarande for framstellning av n-(2-pyridyl)-4-hydroxi-2-metyl-2h-1,2-benso-tiazin-3-karboxamid-1,1-dioxid
US4074048A (en) * 1976-05-10 1978-02-14 Warner-Lambert Company Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides
US4100347A (en) * 1976-06-10 1978-07-11 Pfizer Inc. 3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide
US4289879A (en) * 1980-09-29 1981-09-15 Pfizer Inc. Synthetic method and intermediate for piroxicam

Also Published As

Publication number Publication date
ES8407034A1 (es) 1984-09-01
YU156084A (en) 1985-04-30
CA1187873A (en) 1985-05-28
DK154646B (da) 1988-12-05
EG15847A (en) 1987-04-30
IN159273B (es) 1987-04-25
RO84510B (ro) 1984-08-30
FI75342B (fi) 1988-02-29
YU42804B (en) 1988-12-31
PT75642B (en) 1985-12-09
FI823366A0 (fi) 1982-10-04
PL136540B1 (en) 1986-02-28
GR77345B (es) 1984-09-11
PL238506A1 (en) 1984-04-09
IE822393L (en) 1983-04-05
HK52687A (en) 1987-07-17
KR840001963A (ko) 1984-06-07
NZ202062A (en) 1985-08-30
DK204888A (da) 1988-04-14
PL244761A1 (en) 1984-07-16
AU8891782A (en) 1983-04-14
RO86733B (ro) 1985-05-01
YU222882A (en) 1985-04-30
KR850001223B1 (ko) 1985-08-23
EP0076643B1 (en) 1985-02-20
PH19297A (en) 1986-03-05
ES8400418A1 (es) 1983-11-01
ES522788A0 (es) 1984-09-01
HU186977B (en) 1985-10-28
BG40811A3 (en) 1987-02-16
ATE11916T1 (de) 1985-03-15
DK439482A (da) 1983-04-06
DK154139C (da) 1989-03-06
PL136931B1 (en) 1986-04-30
EP0076643A1 (en) 1983-04-13
RO86733A (ro) 1985-04-17
DK204888D0 (da) 1988-04-14
SG22987G (en) 1987-07-10
NO157140B (no) 1987-10-19
NO823330L (no) 1983-04-06
NO157140C (no) 1988-02-03
BG40812A3 (en) 1987-02-16
ES516208A0 (es) 1983-11-01
DD203051A5 (de) 1983-10-12
DK154139B (da) 1988-10-17
IE53957B1 (en) 1989-04-26
AU534759B2 (en) 1984-02-16
DD216460A5 (de) 1984-12-12
DE3262440D1 (en) 1985-03-28
YU42903B (en) 1988-12-31
FI75342C (fi) 1988-06-09
RO84510A (ro) 1984-06-21
MY8700510A (en) 1987-12-31
PH17991A (en) 1985-02-28
DK154646C (da) 1989-05-08
PT75642A (en) 1982-11-01
FI823366L (fi) 1983-04-06

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Legal Events

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