DK154646C - Fremgangsmaade til fremstilling af piroxicam og mellemprodukter, der foerer til denne forbindelse - Google Patents
Fremgangsmaade til fremstilling af piroxicam og mellemprodukter, der foerer til denne forbindelseInfo
- Publication number
- DK154646C DK154646C DK439482A DK439482A DK154646C DK 154646 C DK154646 C DK 154646C DK 439482 A DK439482 A DK 439482A DK 439482 A DK439482 A DK 439482A DK 154646 C DK154646 C DK 154646C
- Authority
- DK
- Denmark
- Prior art keywords
- piroxicam
- intermediates
- alkyl
- procedure
- relationship
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30874681 | 1981-10-05 | ||
| US06/308,746 US4376204A (en) | 1981-10-05 | 1981-10-05 | 3-Hydroxy 2-methyl benzisothiazolines as intermediates in production of piroxicam |
| US41303682A | 1982-09-02 | 1982-09-02 | |
| US41303682 | 1982-09-02 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK439482A DK439482A (da) | 1983-04-06 |
| DK154646B DK154646B (da) | 1988-12-05 |
| DK154646C true DK154646C (da) | 1989-05-08 |
Family
ID=26976430
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK439482A DK154646C (da) | 1981-10-05 | 1982-10-04 | Fremgangsmaade til fremstilling af piroxicam og mellemprodukter, der foerer til denne forbindelse |
| DK204888A DK154139C (da) | 1981-10-05 | 1988-04-14 | Fremgangsmaade til fremstilling af 4-hydroxy-2-methyl-2h-1,2-benzothiazin-1,1-dioxid-3-carboxylsyrederivater, der kan omdannes til piroxicam |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK204888A DK154139C (da) | 1981-10-05 | 1988-04-14 | Fremgangsmaade til fremstilling af 4-hydroxy-2-methyl-2h-1,2-benzothiazin-1,1-dioxid-3-carboxylsyrederivater, der kan omdannes til piroxicam |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0076643B1 (es) |
| KR (1) | KR850001223B1 (es) |
| AT (1) | ATE11916T1 (es) |
| AU (1) | AU534759B2 (es) |
| BG (2) | BG40811A3 (es) |
| CA (1) | CA1187873A (es) |
| DD (2) | DD216460A5 (es) |
| DE (1) | DE3262440D1 (es) |
| DK (2) | DK154646C (es) |
| EG (1) | EG15847A (es) |
| ES (2) | ES516208A0 (es) |
| FI (1) | FI75342C (es) |
| GR (1) | GR77345B (es) |
| HK (1) | HK52687A (es) |
| HU (1) | HU186977B (es) |
| IE (1) | IE53957B1 (es) |
| IL (1) | IL66921A0 (es) |
| IN (1) | IN159273B (es) |
| MY (1) | MY8700510A (es) |
| NO (1) | NO157140C (es) |
| NZ (1) | NZ202062A (es) |
| PH (2) | PH17991A (es) |
| PL (2) | PL136931B1 (es) |
| PT (1) | PT75642B (es) |
| RO (2) | RO86733B (es) |
| SG (1) | SG22987G (es) |
| YU (2) | YU42804B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU759169B2 (en) | 1997-09-05 | 2003-04-10 | Warner-Lambert Company | Certain benzothiazine dioxide endothelin antagonists and processes for their preparation |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3591584A (en) * | 1968-08-27 | 1971-07-06 | Pfizer | Benzothiazine dioxides |
| US3853862A (en) * | 1973-04-23 | 1974-12-10 | Pfizer | Production of 4-hydroxy-1,2-benzothiazine-3-carboxamides |
| US3891637A (en) * | 1974-10-01 | 1975-06-24 | Pfizer | Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides |
| US3892740A (en) * | 1974-10-15 | 1975-07-01 | Pfizer | Process for the production of carboxamides of oxo-1,2-benzothiazine-1,1-dioxides |
| US3960856A (en) * | 1975-06-20 | 1976-06-01 | Warner-Lambert Company | Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide |
| SE421792B (sv) * | 1976-01-12 | 1982-02-01 | Pfizer | Forfarande for framstellning av n-(2-pyridyl)-4-hydroxi-2-metyl-2h-1,2-benso-tiazin-3-karboxamid-1,1-dioxid |
| US4074048A (en) * | 1976-05-10 | 1978-02-14 | Warner-Lambert Company | Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides |
| US4100347A (en) * | 1976-06-10 | 1978-07-11 | Pfizer Inc. | 3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide |
| US4289879A (en) * | 1980-09-29 | 1981-09-15 | Pfizer Inc. | Synthetic method and intermediate for piroxicam |
-
1982
- 1982-09-22 IN IN719/DEL/82A patent/IN159273B/en unknown
- 1982-09-29 AT AT82305174T patent/ATE11916T1/de not_active IP Right Cessation
- 1982-09-29 DE DE8282305174T patent/DE3262440D1/de not_active Expired
- 1982-09-29 EP EP82305174A patent/EP0076643B1/en not_active Expired
- 1982-09-30 AU AU88917/82A patent/AU534759B2/en not_active Ceased
- 1982-09-30 IL IL66921A patent/IL66921A0/xx not_active IP Right Cessation
- 1982-10-01 GR GR69420A patent/GR77345B/el unknown
- 1982-10-01 PT PT75642A patent/PT75642B/pt not_active IP Right Cessation
- 1982-10-01 NZ NZ202062A patent/NZ202062A/en unknown
- 1982-10-04 BG BG061608A patent/BG40811A3/xx unknown
- 1982-10-04 CA CA000412724A patent/CA1187873A/en not_active Expired
- 1982-10-04 DK DK439482A patent/DK154646C/da not_active IP Right Cessation
- 1982-10-04 PH PH27950A patent/PH17991A/en unknown
- 1982-10-04 NO NO823330A patent/NO157140C/no unknown
- 1982-10-04 ES ES516208A patent/ES516208A0/es active Granted
- 1982-10-04 RO RO112350A patent/RO86733B/ro unknown
- 1982-10-04 IE IE2393/82A patent/IE53957B1/en not_active IP Right Cessation
- 1982-10-04 FI FI823366A patent/FI75342C/fi not_active IP Right Cessation
- 1982-10-04 BG BG058162A patent/BG40812A3/xx unknown
- 1982-10-04 RO RO108738A patent/RO84510B/ro unknown
- 1982-10-04 YU YU2228/82A patent/YU42804B/xx unknown
- 1982-10-05 KR KR8204482A patent/KR850001223B1/ko active
- 1982-10-05 DD DD82257459A patent/DD216460A5/de not_active IP Right Cessation
- 1982-10-05 PL PL1982238506A patent/PL136931B1/pl unknown
- 1982-10-05 DD DD82243802A patent/DD203051A5/de not_active IP Right Cessation
- 1982-10-05 PL PL1982244761A patent/PL136540B1/pl unknown
- 1982-10-05 EG EG594/82A patent/EG15847A/xx active
- 1982-10-05 HU HU823194A patent/HU186977B/hu not_active IP Right Cessation
-
1983
- 1983-05-27 ES ES522788A patent/ES522788A0/es active Granted
-
1984
- 1984-06-07 PH PH30790-AA patent/PH19297A/en unknown
- 1984-09-10 YU YU1560/84A patent/YU42903B/xx unknown
-
1987
- 1987-03-09 SG SG229/87A patent/SG22987G/en unknown
- 1987-07-09 HK HK526/87A patent/HK52687A/xx unknown
- 1987-12-30 MY MY510/87A patent/MY8700510A/xx unknown
-
1988
- 1988-04-14 DK DK204888A patent/DK154139C/da not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |