IL64922A - Phenyl substituted imidazole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Phenyl substituted imidazole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL64922A
IL64922A IL64922A IL6492282A IL64922A IL 64922 A IL64922 A IL 64922A IL 64922 A IL64922 A IL 64922A IL 6492282 A IL6492282 A IL 6492282A IL 64922 A IL64922 A IL 64922A
Authority
IL
Israel
Prior art keywords
hydrogen
compounds
carbon atoms
preparation
pharmaceutical compositions
Prior art date
Application number
IL64922A
Other languages
English (en)
Other versions
IL64922A0 (en
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of IL64922A0 publication Critical patent/IL64922A0/xx
Publication of IL64922A publication Critical patent/IL64922A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Catalysts (AREA)
IL64922A 1981-02-05 1982-02-03 Phenyl substituted imidazole derivatives,their preparation and pharmaceutical compositions containing them IL64922A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8103620A GB2092569B (en) 1981-02-05 1981-02-05 Substituted imidazole derivatives and their preparation and use

Publications (2)

Publication Number Publication Date
IL64922A0 IL64922A0 (en) 1982-04-30
IL64922A true IL64922A (en) 1986-01-31

Family

ID=10519480

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64922A IL64922A (en) 1981-02-05 1982-02-03 Phenyl substituted imidazole derivatives,their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (2) US4514412A (xx)
EP (1) EP0058047B1 (xx)
JP (1) JPS57149273A (xx)
AT (1) ATE10192T1 (xx)
AU (1) AU552322B2 (xx)
CA (1) CA1176259A (xx)
DD (1) DD210451A1 (xx)
DE (1) DE3261153D1 (xx)
DK (2) DK157545C (xx)
FI (1) FI76568C (xx)
GB (1) GB2092569B (xx)
HU (1) HU187564B (xx)
IE (1) IE52362B1 (xx)
IL (1) IL64922A (xx)
NO (1) NO155884C (xx)
NZ (1) NZ199631A (xx)
SU (1) SU1162372A3 (xx)
ZA (1) ZA82717B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI833794A0 (fi) * 1983-10-18 1983-10-18 Farmos Oy Substituerade 2-merkapto-imidazoler
FI844786A0 (fi) * 1984-12-04 1984-12-04 Farmos Oy Terapeutiskt utnyttjbar foerening.
GB8523255D0 (en) * 1985-09-20 1985-10-23 Shell Int Research Imidazoles
GB8626287D0 (en) * 1986-11-04 1986-12-03 Ucb Sa Substituted 1h-imidazoles
JPS63150266A (ja) * 1986-12-12 1988-06-22 Mitsui Petrochem Ind Ltd ベンジルイミダゾ−ル誘導体
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2210875B (en) * 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles
GB8810067D0 (en) * 1988-04-28 1988-06-02 Ucb Sa Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides
AU627559B2 (en) * 1989-03-30 1992-08-27 Farmos-Yhtyma Oy Novel aromatase inhibiting 4(5)-imidazoles
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
FR2732017B1 (fr) * 1995-03-21 2000-09-22 Inst Nat Sante Rech Med Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
KR20050114641A (ko) * 2003-03-07 2005-12-06 아스텔라스세이야쿠 가부시키가이샤 2,6-이치환된 스티릴을 갖는 질소 함유 헤테로환 유도체
BRPI0514812A (pt) * 2004-09-01 2008-06-24 Astellas Pharma Inc derivado de piperidina ou seu sal farmaceuticamente aceitável
US20080146523A1 (en) * 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
HUE026686T2 (en) 2012-05-08 2016-07-28 Lonza Ag Process for the preparation of 2- (2,3-dimethylphenyl) -1-propanal
WO2012172119A2 (en) * 2012-05-08 2012-12-20 Lonza Ltd Method for the preparation of medetomidine
PL2847173T3 (pl) * 2012-05-08 2016-06-30 Lonza Ag Sposób wytwarzania medetomidyny
CN104245678B (zh) 2012-06-28 2016-02-24 隆萨有限公司 用氯丙酮制备美托咪定的方法
US9126914B1 (en) 2012-06-28 2015-09-08 Lonza Ltd. Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal with chloroacetone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356645A (en) * 1964-04-20 1967-12-05 Shell Oil Co Process for curing epoxy resins with a salt of an imidazole and compositions thereof
FR2122395A1 (en) * 1971-01-19 1972-09-01 Berlin Chemie Veb Pharmacologically active imidazoles - by condensing alpha-aminoketones with formamide
DD96070A1 (xx) * 1971-02-23 1973-03-12
JPS54148788A (en) * 1978-05-15 1979-11-21 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation
US4220654A (en) * 1979-06-04 1980-09-02 Merck & Co., Inc. Cyclic imidazole cyanoguanidines
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
GB2069481B (en) * 1980-02-13 1983-07-27 Farmos Oy Substituted imidazole derivatives
JPS624387A (ja) * 1985-07-01 1987-01-10 日本電気株式会社 プリント回路基板

Also Published As

Publication number Publication date
HU187564B (en) 1986-01-28
GB2092569B (en) 1984-09-19
EP0058047A1 (en) 1982-08-18
CA1176259A (en) 1984-10-16
JPS57149273A (en) 1982-09-14
FI820140L (fi) 1982-08-06
NZ199631A (en) 1985-02-28
IL64922A0 (en) 1982-04-30
DE3261153D1 (en) 1984-12-13
IE52362B1 (en) 1987-09-30
FI76568C (fi) 1988-11-10
SU1162372A3 (ru) 1985-06-15
IE820241L (en) 1982-08-05
USRE32400E (en) 1987-04-14
DK158351C (da) 1990-10-08
AU8014482A (en) 1982-08-12
DD210451A1 (de) 1984-06-13
GB2092569A (en) 1982-08-18
DK157545B (da) 1990-01-22
ATE10192T1 (de) 1984-11-15
NO820340L (no) 1982-08-06
DK157545C (da) 1990-06-11
NO155884B (no) 1987-03-09
EP0058047B1 (en) 1984-11-07
DK158351B (da) 1990-05-07
DK44682A (da) 1982-08-06
DK630786D0 (da) 1986-12-29
FI76568B (fi) 1988-07-29
DK630786A (da) 1986-12-29
NO155884C (no) 1987-06-17
AU552322B2 (en) 1986-05-29
US4514412A (en) 1985-04-30
ZA82717B (en) 1983-01-26
JPH0261458B2 (xx) 1990-12-20

Similar Documents

Publication Publication Date Title
DE3261153D1 (en) Substituted imidazole derivatives and their preparation and use
DE3271269D1 (en) Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same
GB2069481B (en) Substituted imidazole derivatives
GB2110663B (en) Imidazole derivatives

Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void