NO155884C - Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazol-derivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazol-derivater.

Info

Publication number
NO155884C
NO155884C NO820340A NO820340A NO155884C NO 155884 C NO155884 C NO 155884C NO 820340 A NO820340 A NO 820340A NO 820340 A NO820340 A NO 820340A NO 155884 C NO155884 C NO 155884C
Authority
NO
Norway
Prior art keywords
hydrogen
compounds
carbon atoms
preparation
image
Prior art date
Application number
NO820340A
Other languages
English (en)
Other versions
NO820340L (no
NO155884B (no
Inventor
Arto Johannes Karjalainen
Kauko Oiva Antero Kurkela
Seppo Sulevi Lennart Parhi
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of NO820340L publication Critical patent/NO820340L/no
Publication of NO155884B publication Critical patent/NO155884B/no
Publication of NO155884C publication Critical patent/NO155884C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Catalysts (AREA)
NO820340A 1981-02-05 1982-02-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazol-derivater. NO155884C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8103620A GB2092569B (en) 1981-02-05 1981-02-05 Substituted imidazole derivatives and their preparation and use

Publications (3)

Publication Number Publication Date
NO820340L NO820340L (no) 1982-08-06
NO155884B NO155884B (no) 1987-03-09
NO155884C true NO155884C (no) 1987-06-17

Family

ID=10519480

Family Applications (1)

Application Number Title Priority Date Filing Date
NO820340A NO155884C (no) 1981-02-05 1982-02-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazol-derivater.

Country Status (18)

Country Link
US (2) US4514412A (no)
EP (1) EP0058047B1 (no)
JP (1) JPS57149273A (no)
AT (1) ATE10192T1 (no)
AU (1) AU552322B2 (no)
CA (1) CA1176259A (no)
DD (1) DD210451A1 (no)
DE (1) DE3261153D1 (no)
DK (2) DK157545C (no)
FI (1) FI76568C (no)
GB (1) GB2092569B (no)
HU (1) HU187564B (no)
IE (1) IE52362B1 (no)
IL (1) IL64922A (no)
NO (1) NO155884C (no)
NZ (1) NZ199631A (no)
SU (1) SU1162372A3 (no)
ZA (1) ZA82717B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI833794A0 (fi) * 1983-10-18 1983-10-18 Farmos Oy Substituerade 2-merkapto-imidazoler
FI844786A0 (fi) * 1984-12-04 1984-12-04 Farmos Oy Terapeutiskt utnyttjbar foerening.
GB8523255D0 (en) * 1985-09-20 1985-10-23 Shell Int Research Imidazoles
GB8626287D0 (en) * 1986-11-04 1986-12-03 Ucb Sa Substituted 1h-imidazoles
JPS63150266A (ja) * 1986-12-12 1988-06-22 Mitsui Petrochem Ind Ltd ベンジルイミダゾ−ル誘導体
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2210875B (en) * 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles
GB8810067D0 (en) 1988-04-28 1988-06-02 Ucb Sa Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides
JPH032168A (ja) * 1989-03-30 1991-01-08 Farmos Yhtymae Oy アロマターゼ阻害活性を有する新規な４（５）―イミダゾール
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
FR2732017B1 (fr) * 1995-03-21 2000-09-22 Inst Nat Sante Rech Med Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
AU2004218115A1 (en) * 2003-03-07 2004-09-16 Astellas Pharma Inc. Nitrogenous heterocyclic derivative having 2,6-disubstituted styryl
ZA200702379B (en) * 2004-09-01 2008-07-30 Astellas Pharma Inc Piperidine derivative or pharmaceutically acceptable salt thereof
US20080146523A1 (en) * 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
WO2012172119A2 (en) * 2012-05-08 2012-12-20 Lonza Ltd Method for the preparation of medetomidine
ES2557638T3 (es) 2012-05-08 2016-01-27 Lonza Ltd Método para la preparación de 2-(2,3-dimetilfenil)-1-propanal
DK2847173T3 (en) * 2012-05-08 2016-04-04 Lonza Ag METHOD OF PRODUCING Medetomidine
MY165118A (en) 2012-06-28 2018-02-28 Lonza Ag Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal with chloroacetone
WO2013011157A1 (en) 2012-06-28 2013-01-24 Lonza Ltd Method for preparation of medetomidine with chloroacetone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356645A (en) * 1964-04-20 1967-12-05 Shell Oil Co Process for curing epoxy resins with a salt of an imidazole and compositions thereof
FR2122395A1 (en) * 1971-01-19 1972-09-01 Berlin Chemie Veb Pharmacologically active imidazoles - by condensing alpha-aminoketones with formamide
DD96070A1 (no) * 1971-02-23 1973-03-12
JPS54148788A (en) * 1978-05-15 1979-11-21 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation
US4220654A (en) * 1979-06-04 1980-09-02 Merck & Co., Inc. Cyclic imidazole cyanoguanidines
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
GB2069481B (en) * 1980-02-13 1983-07-27 Farmos Oy Substituted imidazole derivatives
JPS624387A (ja) * 1985-07-01 1987-01-10 日本電気株式会社 プリント回路基板

Also Published As

Publication number Publication date
DK630786D0 (da) 1986-12-29
DK157545B (da) 1990-01-22
DK157545C (da) 1990-06-11
IE52362B1 (en) 1987-09-30
EP0058047A1 (en) 1982-08-18
FI76568C (fi) 1988-11-10
DE3261153D1 (en) 1984-12-13
ATE10192T1 (de) 1984-11-15
CA1176259A (en) 1984-10-16
DK44682A (da) 1982-08-06
ZA82717B (en) 1983-01-26
HU187564B (en) 1986-01-28
IE820241L (en) 1982-08-05
AU8014482A (en) 1982-08-12
DK158351C (da) 1990-10-08
EP0058047B1 (en) 1984-11-07
DK158351B (da) 1990-05-07
NO820340L (no) 1982-08-06
JPS57149273A (en) 1982-09-14
FI76568B (fi) 1988-07-29
NZ199631A (en) 1985-02-28
SU1162372A3 (ru) 1985-06-15
DD210451A1 (de) 1984-06-13
IL64922A0 (en) 1982-04-30
GB2092569B (en) 1984-09-19
NO155884B (no) 1987-03-09
GB2092569A (en) 1982-08-18
US4514412A (en) 1985-04-30
AU552322B2 (en) 1986-05-29
JPH0261458B2 (no) 1990-12-20
DK630786A (da) 1986-12-29
IL64922A (en) 1986-01-31
USRE32400E (en) 1987-04-14
FI820140L (fi) 1982-08-06

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NO155884C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazol-derivater.
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