JPS57149273A - Imidazole derivative, manufacture and medicinal composition containing same as effective component - Google Patents

Imidazole derivative, manufacture and medicinal composition containing same as effective component

Info

Publication number
JPS57149273A
JPS57149273A JP57015445A JP1544582A JPS57149273A JP S57149273 A JPS57149273 A JP S57149273A JP 57015445 A JP57015445 A JP 57015445A JP 1544582 A JP1544582 A JP 1544582A JP S57149273 A JPS57149273 A JP S57149273A
Authority
JP
Japan
Prior art keywords
hydrogen
compounds
carbon atoms
manufacture
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57015445A
Other languages
English (en)
Other versions
JPH0261458B2 (ja
Inventor
Yohannesu Karuyarainen Aruto
Oiba Anchiro Kurukera Kauko
Surebi Rennaruto Paruh Setsupo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUARUMOSUUYUHICHIYUME OYU
Original Assignee
FUARUMOSUUYUHICHIYUME OYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUARUMOSUUYUHICHIYUME OYU filed Critical FUARUMOSUUYUHICHIYUME OYU
Publication of JPS57149273A publication Critical patent/JPS57149273A/ja
Publication of JPH0261458B2 publication Critical patent/JPH0261458B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Catalysts (AREA)
JP57015445A 1981-02-05 1982-02-01 Imidazole derivative, manufacture and medicinal composition containing same as effective component Granted JPS57149273A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8103620A GB2092569B (en) 1981-02-05 1981-02-05 Substituted imidazole derivatives and their preparation and use

Publications (2)

Publication Number Publication Date
JPS57149273A true JPS57149273A (en) 1982-09-14
JPH0261458B2 JPH0261458B2 (ja) 1990-12-20

Family

ID=10519480

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57015445A Granted JPS57149273A (en) 1981-02-05 1982-02-01 Imidazole derivative, manufacture and medicinal composition containing same as effective component

Country Status (18)

Country Link
US (2) US4514412A (ja)
EP (1) EP0058047B1 (ja)
JP (1) JPS57149273A (ja)
AT (1) ATE10192T1 (ja)
AU (1) AU552322B2 (ja)
CA (1) CA1176259A (ja)
DD (1) DD210451A1 (ja)
DE (1) DE3261153D1 (ja)
DK (2) DK157545C (ja)
FI (1) FI76568C (ja)
GB (1) GB2092569B (ja)
HU (1) HU187564B (ja)
IE (1) IE52362B1 (ja)
IL (1) IL64922A (ja)
NO (1) NO155884C (ja)
NZ (1) NZ199631A (ja)
SU (1) SU1162372A3 (ja)
ZA (1) ZA82717B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63150266A (ja) * 1986-12-12 1988-06-22 Mitsui Petrochem Ind Ltd ベンジルイミダゾ−ル誘導体

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI833794A0 (fi) * 1983-10-18 1983-10-18 Farmos Oy Substituerade 2-merkapto-imidazoler
FI844786A0 (fi) * 1984-12-04 1984-12-04 Farmos Oy Terapeutiskt utnyttjbar foerening.
GB8523255D0 (en) * 1985-09-20 1985-10-23 Shell Int Research Imidazoles
GB8626287D0 (en) * 1986-11-04 1986-12-03 Ucb Sa Substituted 1h-imidazoles
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2210875B (en) * 1987-10-09 1991-05-29 Farmos Oy Aromatase inhibiting 4(5)-imidazoles
GB8810067D0 (en) * 1988-04-28 1988-06-02 Ucb Sa Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides
AU627559B2 (en) * 1989-03-30 1992-08-27 Farmos-Yhtyma Oy Novel aromatase inhibiting 4(5)-imidazoles
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
FR2732017B1 (fr) * 1995-03-21 2000-09-22 Inst Nat Sante Rech Med Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
KR20050114641A (ko) * 2003-03-07 2005-12-06 아스텔라스세이야쿠 가부시키가이샤 2,6-이치환된 스티릴을 갖는 질소 함유 헤테로환 유도체
BRPI0514812A (pt) * 2004-09-01 2008-06-24 Astellas Pharma Inc derivado de piperidina ou seu sal farmaceuticamente aceitável
US20080146523A1 (en) * 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
HUE026686T2 (en) 2012-05-08 2016-07-28 Lonza Ag Process for the preparation of 2- (2,3-dimethylphenyl) -1-propanal
WO2012172119A2 (en) * 2012-05-08 2012-12-20 Lonza Ltd Method for the preparation of medetomidine
PL2847173T3 (pl) * 2012-05-08 2016-06-30 Lonza Ag Sposób wytwarzania medetomidyny
CN104245678B (zh) 2012-06-28 2016-02-24 隆萨有限公司 用氯丙酮制备美托咪定的方法
US9126914B1 (en) 2012-06-28 2015-09-08 Lonza Ltd. Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal with chloroacetone

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2122395A1 (en) * 1971-01-19 1972-09-01 Berlin Chemie Veb Pharmacologically active imidazoles - by condensing alpha-aminoketones with formamide
FR2126173A1 (en) * 1971-02-23 1972-10-06 Berlin Chemie Veb Imidazole derivs prepn - with pharmacolical effects by cyclizing a cylaminoketones
JPS55164678A (en) * 1979-06-04 1980-12-22 Merck & Co Inc Novel cyclic imidazolecyanoguanidine
JPS56128768A (en) * 1980-02-13 1981-10-08 Farmos Oy Substituted imidazole derivative, its manufacture and medicine as effective component
JPS624387A (ja) * 1985-07-01 1987-01-10 日本電気株式会社 プリント回路基板

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356645A (en) * 1964-04-20 1967-12-05 Shell Oil Co Process for curing epoxy resins with a salt of an imidazole and compositions thereof
JPS54148788A (en) * 1978-05-15 1979-11-21 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2122395A1 (en) * 1971-01-19 1972-09-01 Berlin Chemie Veb Pharmacologically active imidazoles - by condensing alpha-aminoketones with formamide
FR2126173A1 (en) * 1971-02-23 1972-10-06 Berlin Chemie Veb Imidazole derivs prepn - with pharmacolical effects by cyclizing a cylaminoketones
JPS55164678A (en) * 1979-06-04 1980-12-22 Merck & Co Inc Novel cyclic imidazolecyanoguanidine
JPS56128768A (en) * 1980-02-13 1981-10-08 Farmos Oy Substituted imidazole derivative, its manufacture and medicine as effective component
JPS56128767A (en) * 1980-02-13 1981-10-08 Farmos Oy Substituted imidazole derivative, its manufacture and medicine as effective component
JPS624387A (ja) * 1985-07-01 1987-01-10 日本電気株式会社 プリント回路基板

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63150266A (ja) * 1986-12-12 1988-06-22 Mitsui Petrochem Ind Ltd ベンジルイミダゾ−ル誘導体

Also Published As

Publication number Publication date
HU187564B (en) 1986-01-28
GB2092569B (en) 1984-09-19
EP0058047A1 (en) 1982-08-18
CA1176259A (en) 1984-10-16
FI820140L (fi) 1982-08-06
NZ199631A (en) 1985-02-28
IL64922A0 (en) 1982-04-30
DE3261153D1 (en) 1984-12-13
IE52362B1 (en) 1987-09-30
FI76568C (fi) 1988-11-10
SU1162372A3 (ru) 1985-06-15
IE820241L (en) 1982-08-05
USRE32400E (en) 1987-04-14
DK158351C (da) 1990-10-08
AU8014482A (en) 1982-08-12
DD210451A1 (de) 1984-06-13
GB2092569A (en) 1982-08-18
DK157545B (da) 1990-01-22
ATE10192T1 (de) 1984-11-15
NO820340L (no) 1982-08-06
DK157545C (da) 1990-06-11
NO155884B (no) 1987-03-09
EP0058047B1 (en) 1984-11-07
DK158351B (da) 1990-05-07
DK44682A (da) 1982-08-06
DK630786D0 (da) 1986-12-29
IL64922A (en) 1986-01-31
FI76568B (fi) 1988-07-29
DK630786A (da) 1986-12-29
NO155884C (no) 1987-06-17
AU552322B2 (en) 1986-05-29
US4514412A (en) 1985-04-30
ZA82717B (en) 1983-01-26
JPH0261458B2 (ja) 1990-12-20

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JPS57149273A (en) Imidazole derivative, manufacture and medicinal composition containing same as effective component
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