IL64091A - Arylimidazo(1,2-a)pyridine acetamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Arylimidazo(1,2-a)pyridine acetamide derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL64091A
IL64091A IL64091A IL6409181A IL64091A IL 64091 A IL64091 A IL 64091A IL 64091 A IL64091 A IL 64091A IL 6409181 A IL6409181 A IL 6409181A IL 64091 A IL64091 A IL 64091A
Authority
IL
Israel
Prior art keywords
pyridine
arylimidazo
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL64091A
Other languages
English (en)
Other versions
IL64091A0 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9247171&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL64091(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL64091A0 publication Critical patent/IL64091A0/xx
Publication of IL64091A publication Critical patent/IL64091A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
IL64091A 1980-10-22 1981-10-21 Arylimidazo(1,2-a)pyridine acetamide derivatives,their preparation and pharmaceutical compositions containing them IL64091A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8022537A FR2492382A1 (fr) 1980-10-22 1980-10-22 Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
IL64091A0 IL64091A0 (en) 1982-01-31
IL64091A true IL64091A (en) 1984-12-31

Family

ID=9247171

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64091A IL64091A (en) 1980-10-22 1981-10-21 Arylimidazo(1,2-a)pyridine acetamide derivatives,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (2) US4382938A (xx)
EP (1) EP0050563B1 (xx)
JP (1) JPS5798283A (xx)
AT (1) ATE7393T1 (xx)
AU (1) AU544345B2 (xx)
CA (1) CA1157470A (xx)
DE (1) DE3163524D1 (xx)
DK (1) DK154429C (xx)
ES (1) ES506412A0 (xx)
FI (1) FI71143C (xx)
FR (1) FR2492382A1 (xx)
GR (1) GR74701B (xx)
IE (1) IE51686B1 (xx)
IL (1) IL64091A (xx)
LU (1) LU88228I2 (xx)
MX (1) MX6463E (xx)
NL (1) NL930044I2 (xx)
NO (1) NO155664C (xx)
NZ (1) NZ198722A (xx)
OA (1) OA07076A (xx)
PT (1) PT73863B (xx)
ZA (1) ZA817297B (xx)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525602A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2525601A1 (fr) * 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2568879B1 (fr) * 1984-08-07 1986-12-12 Synthelabo Imidazo(1,2-a)quinolines, leur preparation et leur application en therapeutique
FR2581646B1 (fr) * 1985-05-07 1987-09-18 Synthelabo Derives d'imidazopyridine, leur preparation et leur application en therapeutique
DE3769333D1 (de) * 1986-01-22 1991-05-23 Synthelabo Acylaminomethylimidazo(1,2-a)pyrimidinderivate, ihre herstellung und therapeutische verwendung.
FR2593179B1 (fr) * 1986-01-22 1988-04-01 Synthelabo Derives d'imidazo(1,2-a)quinoleines, leur preparation et leur application en therapeutique
FR2593817B1 (fr) * 1986-01-31 1988-04-15 Synthelabo Derives de tetrahydro-5,6,7,8 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
FR2599368B1 (fr) * 1986-06-02 1988-08-05 Synthelabo Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique
FR2600650B1 (fr) * 1986-06-27 1988-09-09 Synthelabo Procede de preparation d'imidazopyridines et composes intermediaires
FR2606411B1 (fr) * 1986-11-07 1989-04-07 Synthelabo Imidazopyridine-acetamides, leur preparation et leur application en therapeutique
FR2606410B1 (fr) * 1986-11-07 1989-02-24 Synthelabo Imidazopyridines, leur preparation et leur application en therapeutique
FR2606409B1 (fr) * 1986-11-07 1989-05-05 Synthelabo Derives d'imidazopyridine, leur preparation et leur application en therapeutique
ES2026666T3 (es) * 1987-03-27 1992-05-01 Synthelabo Procedimiento para preparar derivados de imidazopiridinas.
FR2612927B1 (fr) * 1987-03-27 1989-06-09 Synthelabo Derives d'imidazopyridines, leur preparation et leur application en therapeutique
FR2612928B1 (fr) * 1987-03-27 1989-06-16 Synthelabo Derives hydroxyles d'imidazopyridines, leur preparation et leur application en therapeutique
US5032595A (en) * 1989-11-24 1991-07-16 Fidia-Georgetown Institute For The Neurosciences Method of stimulating steroidogenesis with alpidem
US5912246A (en) * 1995-02-15 1999-06-15 Pharmacia & Upjohn Company Imidazo 1,2-a!pyridines for the treatment of CNS and cardiac diseases
IT1276522B1 (it) * 1995-04-07 1997-10-31 Elena Benincasa Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
AUPP278498A0 (en) 1998-04-03 1998-04-30 Australian Nuclear Science & Technology Organisation Peripheral benzodiazepine receptor binding agents
EP1005863A1 (en) * 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof
NL1014634C1 (nl) * 1999-03-25 2000-08-03 Synthon Bv Zolpidemzouten.
PT1038875E (pt) 1999-03-25 2003-10-31 Synthon Bv Derivados de imidazopiridina e processo para os preparar
US6333345B1 (en) 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) * 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
AU5066101A (en) * 2000-04-13 2001-10-30 Synthon B.V. Modified release formulations containing a hypnotic agent
DE60125429T2 (de) * 2000-04-24 2007-09-27 Teva Pharmaceutical Industries Ltd. Zolpidem hemitartrat solvat
EP1600159A1 (en) 2000-04-24 2005-11-30 Teva Pharmaceutical Industries Ltd A method for synthesizing different Zolpidem hemitartrate derivatives
AU2001264932A1 (en) * 2000-05-26 2001-12-11 Neurogen Corporation Oxo-imidazopyrimidine-carboxamides and their use as gaba brain receptor ligands
AU2001270297A1 (en) 2000-06-30 2002-01-14 Neurogen Corporation 2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands
IT1318624B1 (it) * 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
DE10040016A1 (de) * 2000-08-16 2002-02-28 Boehringer Ingelheim Pharma Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US6514969B2 (en) * 2000-08-16 2003-02-04 Boehringer Ingelheim Pharma Kg β-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions
AU2000264428A1 (en) * 2000-08-17 2002-02-25 Cilag A.G. Process for the preparation of imidazopyridines
EP1370515A2 (en) * 2000-08-29 2003-12-17 Ranbaxy Laboratories, Ltd. Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
DE10117183A1 (de) * 2001-04-05 2002-10-10 Gruenenthal Gmbh Verwendung von substituierten Imidazo[1,2-a]-pyridinverbindungen als Arzneimittel
KR100433502B1 (ko) * 2001-10-10 2004-06-07 철 양 확장부가 형성된 종이컵
DE10247271A1 (de) * 2002-10-10 2004-08-26 Grünenthal GmbH Substituierte C-Imidazo[1,2-a]pyridin-3-yle
MXPA05006438A (es) * 2002-12-18 2005-09-08 Mallinckrodt Inc Derivados de acetamidas de heteroarilo.
US20040204443A1 (en) * 2003-01-27 2004-10-14 Arthur Zaks Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
WO2005010002A1 (en) * 2003-07-31 2005-02-03 Ranbaxy Laboratories Limited Process for the synthesis of zolpidem
EP1682549B1 (en) * 2003-10-28 2010-09-22 Sepracor Inc. Imidazo[1,2-a]pyridine anxiolytics
ES2515092T3 (es) 2003-12-11 2014-10-29 Sunovion Pharmaceuticals Inc. Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión
KR20130006523A (ko) * 2004-02-17 2013-01-16 트랜스셉트 파마슈티칼스, 인코포레이티드 구강 점막을 가로지르는 수면제 전달용 조성물 및 이의 사용 방법
AU2005215376B2 (en) 2004-02-18 2011-01-20 Sunovion Pharmaceuticals Inc. Dopamine-agonist combination therapy with sedatives for improving sleep quality
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
US20060084806A1 (en) * 2004-07-21 2006-04-20 Ramasubramanian Sridharan Processes for the preparation of imidazo[1,2-a] pyridine derivatives
FR2874611B1 (fr) * 2004-08-31 2006-11-17 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20070287740A1 (en) * 2005-05-25 2007-12-13 Transcept Pharmaceuticals, Inc. Compositions and methods of treating middle-of-the night insomnia
KR20080031208A (ko) * 2005-05-25 2008-04-08 트랜스셉트 파마슈티칼스, 인코포레이티드 야반 불면증을 치료하기 위한 고체 조성물 및 방법
US20070225322A1 (en) * 2005-05-25 2007-09-27 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the night insomnia
US20070020333A1 (en) * 2005-07-20 2007-01-25 Chin-Chih Chiang Controlled release of hypnotic agents
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
DE602006008339D1 (en) 2005-11-18 2009-09-17 Synhton B V Zolpidemtabletten
EP1803722A1 (en) 2006-01-03 2007-07-04 Ferrer Internacional, S.A. Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof
US8309104B2 (en) 2006-03-02 2012-11-13 Watson Pharmaceuticals, Inc. Oral controlled release formulation for sedative and hypnotic agents
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP1845098A1 (en) * 2006-03-29 2007-10-17 Ferrer Internacional, S.A. Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
JP5528105B2 (ja) * 2006-06-05 2014-06-25 オースペックス・ファーマシューティカルズ・インコーポレイテッド 催眠効果を持つ置換イミダゾピリジン化合物の調製と利用
AU2007288124B2 (en) * 2006-08-24 2013-04-04 Australian Nuclear Science & Technology Organisation Fluorinated ligands for targeting peripheral benzodiazepine receptors
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
US20090076066A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched zolpidem
TW200918102A (en) * 2007-10-24 2009-05-01 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
WO2009085310A1 (en) * 2007-12-26 2009-07-09 Teva Pharmaceutical Industries Ltd. Extended-release pharmaceutical compositions containing zolpidem
WO2010020000A1 (en) * 2008-08-19 2010-02-25 The University Of Sydney Novel compounds and their uses in diagnosis
US10478438B2 (en) 2008-10-16 2019-11-19 David Reed Helton Treatment of organophosphate exposure with ocinaplon
US8555875B2 (en) * 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2010122576A1 (en) 2009-04-20 2010-10-28 Matrix Laboratories Ltd Improved process for the preparation of 6-methyl-2-[4-methyl phenyl] imidazo [1, 2-a] pyridine-3-n, n-dimethyl acetamide.
JP5433508B2 (ja) * 2009-06-25 2014-03-05 高田製薬株式会社 ゾルピデム酒石酸塩含有内用液剤
CN102234275B (zh) * 2010-04-27 2015-12-16 溧阳合誉药物科技有限公司 治疗失眠的氘代咪唑并[1,2-a]吡啶衍生物、制备方法及其应用
US8741888B2 (en) 2010-11-09 2014-06-03 Carl A. Forest Sleep aid composition and method
IN2013MU02428A (xx) * 2013-07-22 2015-06-19 3A Chemie Private Ltd
EP3239150B1 (en) * 2014-12-24 2020-02-05 Takeda Pharmaceutical Company Limited Heterocyclic compound
EP3468545A4 (en) 2016-06-08 2020-07-22 President and Fellows of Harvard College METHODS AND COMPOSITIONS FOR REDUCING TACTILE DYSFUNCTION AND ANXIETY RELATED TO AUTISM SPECTRUM DISORDER, RETT SYNDROME AND FRAGILE X SYNDROME
EP3774800A1 (en) * 2018-03-28 2021-02-17 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
AU2019279858A1 (en) * 2018-05-29 2020-11-26 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
JP2021050161A (ja) 2019-09-25 2021-04-01 武田薬品工業株式会社 複素環化合物及びその用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3336194A (en) * 1963-04-30 1967-08-15 Merck & Co Inc Indolyl acid amides
GB1076089A (en) * 1965-11-09 1967-07-19 Selvi & C Lab Bioterapico New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof

Also Published As

Publication number Publication date
US4382938A (en) 1983-05-10
IE812470L (en) 1982-04-22
PT73863A (fr) 1981-11-01
NO155664B (no) 1987-01-26
AU7668781A (en) 1983-04-28
ATE7393T1 (de) 1984-05-15
EP0050563A1 (fr) 1982-04-28
NZ198722A (en) 1984-10-19
PT73863B (fr) 1983-11-07
EP0050563B1 (fr) 1984-05-09
NO155664C (no) 1987-05-06
IE51686B1 (en) 1987-02-04
CA1157470A (en) 1983-11-22
AU544345B2 (en) 1985-05-23
MX6463E (es) 1985-06-06
IL64091A0 (en) 1982-01-31
NL930044I1 (nl) 1993-08-02
JPS637545B2 (xx) 1988-02-17
FI71143C (fi) 1986-11-24
ES8207537A1 (es) 1982-09-16
DK154429C (da) 1989-04-17
US4460592A (en) 1984-07-17
LU88228I2 (xx) 1994-02-03
FI71143B (fi) 1986-08-14
OA07076A (fr) 1984-01-31
NO813551L (no) 1982-04-23
ZA817297B (en) 1982-09-29
DK154429B (da) 1988-11-14
DK465181A (da) 1982-04-23
FR2492382A1 (fr) 1982-04-23
FI813288L (fi) 1982-04-23
DE3163524D1 (en) 1984-06-14
FR2492382B1 (xx) 1983-07-29
NL930044I2 (nl) 1993-09-16
GR74701B (xx) 1984-07-04
ES506412A0 (es) 1982-09-16
JPS5798283A (en) 1982-06-18

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