IL61922A - Angiotensin-ii analogues containing an alpha-hydroxycarboxylic acid residue in position 8,and a process for the preparation thereof - Google Patents

Angiotensin-ii analogues containing an alpha-hydroxycarboxylic acid residue in position 8,and a process for the preparation thereof

Info

Publication number
IL61922A
IL61922A IL61922A IL6192281A IL61922A IL 61922 A IL61922 A IL 61922A IL 61922 A IL61922 A IL 61922A IL 6192281 A IL6192281 A IL 6192281A IL 61922 A IL61922 A IL 61922A
Authority
IL
Israel
Prior art keywords
radical
group
nitrogen atom
protective group
atom
Prior art date
Application number
IL61922A
Other languages
English (en)
Other versions
IL61922A0 (en
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL61922A0 publication Critical patent/IL61922A0/xx
Publication of IL61922A publication Critical patent/IL61922A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL61922A 1980-01-18 1981-01-16 Angiotensin-ii analogues containing an alpha-hydroxycarboxylic acid residue in position 8,and a process for the preparation thereof IL61922A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU8080100A HU181008B (en) 1980-01-18 1980-01-18 Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position

Publications (2)

Publication Number Publication Date
IL61922A0 IL61922A0 (en) 1981-02-27
IL61922A true IL61922A (en) 1984-01-31

Family

ID=10947908

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61922A IL61922A (en) 1980-01-18 1981-01-16 Angiotensin-ii analogues containing an alpha-hydroxycarboxylic acid residue in position 8,and a process for the preparation thereof

Country Status (19)

Country Link
US (1) US4330532A (cs)
EP (1) EP0034260B1 (cs)
JP (1) JPS56142251A (cs)
AT (1) ATE4197T1 (cs)
AU (1) AU541000B2 (cs)
CA (1) CA1149377A (cs)
CS (1) CS219939B2 (cs)
DE (1) DE3160608D1 (cs)
DK (1) DK149777C (cs)
ES (1) ES8201129A1 (cs)
FI (1) FI73225C (cs)
HU (1) HU181008B (cs)
IL (1) IL61922A (cs)
IN (1) IN153279B (cs)
NO (1) NO151409C (cs)
PH (1) PH17196A (cs)
PL (1) PL130448B1 (cs)
SU (1) SU993816A3 (cs)
YU (1) YU42550B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
DE19529604A1 (de) * 1995-08-11 1997-02-13 Bayer Ag Endoparasitizide Mittel auf Basis von Didepsipeptiden, neue Didepsipeptide und ein Verfahren zu ihrer Herstellung
US9572856B2 (en) 2009-12-16 2017-02-21 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Method of treating low blood pressure
CA2910601A1 (en) 2013-04-26 2014-10-30 La Jolla Pharmaceutical Company Compositions and methods for treating renal failure
KR20220028125A (ko) 2013-12-18 2022-03-08 더 조지 워싱턴 유니버시티 저혈압의 치료를 위한 안지오텐신 ii 단독 또는 조합
JP2019501201A (ja) 2016-01-07 2019-01-17 ラ ホヤ ファーマシューティカル カンパニーＬａ Ｊｏｌｌａ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏｍｐａｎｙ アンジオテンシンｉｉの投与方法
WO2018191678A1 (en) 2017-04-14 2018-10-18 La Jolla Pharmaceutical Company Methods for administering angiotensin ii

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947575A (en) * 1969-06-30 1976-03-30 E. R. Squibb & Sons, Inc. Peptides as argiotensin converting enzyme inhibitors
DE2323322A1 (de) * 1973-05-09 1974-11-28 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3923769A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus {8 N-Me-Ile{40 ,Ile{hu 8{b {9 -Angiotensin II as an angiotensin antagonist
US3923770A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus {8 Me{hd 2{b Gly{hu 1{b , Ile{hu 8{b {9 -Anziotensin II as an angiotensin antagonist
US3915948A (en) * 1974-08-05 1975-10-28 Morton Norwich Products Inc Sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-proline
DE2457463A1 (de) * 1974-12-05 1976-06-10 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3975365A (en) * 1975-01-27 1976-08-17 G. D. Searle & Co. Inhibitory octapeptides angiotensin II
US3976770A (en) * 1975-02-10 1976-08-24 Francis Merlin Bumpus Sar'-(OMe)Thr8 Angiotensin II as an angiotensin II antagonist
HU177134B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity
HU177133B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha- amino-oxy-acid in position 1 with angiotensin ii antagonist activity

Also Published As

Publication number Publication date
FI73225C (fi) 1987-09-10
ES498583A0 (es) 1981-12-01
ES8201129A1 (es) 1981-12-01
ATE4197T1 (de) 1983-08-15
DK20481A (da) 1981-07-19
NO810149L (no) 1981-07-20
AU541000B2 (en) 1984-12-13
FI810123L (fi) 1981-07-19
JPS56142251A (en) 1981-11-06
DE3160608D1 (en) 1983-08-25
EP0034260A1 (de) 1981-08-26
HU181008B (en) 1983-05-30
IL61922A0 (en) 1981-02-27
FI73225B (fi) 1987-05-29
YU42550B (en) 1988-10-31
IN153279B (cs) 1984-06-23
NO151409C (no) 1985-04-10
PL130448B1 (en) 1984-08-31
PL229223A1 (cs) 1982-03-01
NO151409B (no) 1984-12-27
DK149777B (da) 1986-09-29
SU993816A3 (ru) 1983-01-30
DK149777C (da) 1987-04-21
US4330532A (en) 1982-05-18
PH17196A (en) 1984-06-19
EP0034260B1 (de) 1983-07-20
AU6627681A (en) 1981-07-23
CS219939B2 (en) 1983-03-25
CA1149377A (en) 1983-07-05
YU9381A (en) 1983-09-30

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