NO810149L - Fremgangsmaate ved fremstilling av nye angiotensin-ii-analoger inneholdende en alfa-hydroxycarboxylsyrerest i 8-stilling - Google Patents

Fremgangsmaate ved fremstilling av nye angiotensin-ii-analoger inneholdende en alfa-hydroxycarboxylsyrerest i 8-stilling

Info

Publication number
NO810149L
NO810149L NO810149A NO810149A NO810149L NO 810149 L NO810149 L NO 810149L NO 810149 A NO810149 A NO 810149A NO 810149 A NO810149 A NO 810149A NO 810149 L NO810149 L NO 810149L
Authority
NO
Norway
Prior art keywords
radical
group
nitrogen atom
protective group
atom
Prior art date
Application number
NO810149A
Other languages
English (en)
Other versions
NO151409B (no
NO151409C (no
Inventor
Olga Nyeki
Lajos Kisfaludy
Egon Karpati
Laszlo Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NO810149L publication Critical patent/NO810149L/no
Publication of NO151409B publication Critical patent/NO151409B/no
Publication of NO151409C publication Critical patent/NO151409C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/14Angiotensins: Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO810149A 1980-01-18 1981-01-16 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive angiotensin-ii-analoger inneholdende en alfa-hydroxycarboxylsyrerest i 8-stilling NO151409C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU8080100A HU181008B (en) 1980-01-18 1980-01-18 Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position

Publications (3)

Publication Number Publication Date
NO810149L true NO810149L (no) 1981-07-20
NO151409B NO151409B (no) 1984-12-27
NO151409C NO151409C (no) 1985-04-10

Family

ID=10947908

Family Applications (1)

Application Number Title Priority Date Filing Date
NO810149A NO151409C (no) 1980-01-18 1981-01-16 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive angiotensin-ii-analoger inneholdende en alfa-hydroxycarboxylsyrerest i 8-stilling

Country Status (19)

Country Link
US (1) US4330532A (no)
EP (1) EP0034260B1 (no)
JP (1) JPS56142251A (no)
AT (1) ATE4197T1 (no)
AU (1) AU541000B2 (no)
CA (1) CA1149377A (no)
CS (1) CS219939B2 (no)
DE (1) DE3160608D1 (no)
DK (1) DK149777C (no)
ES (1) ES8201129A1 (no)
FI (1) FI73225C (no)
HU (1) HU181008B (no)
IL (1) IL61922A (no)
IN (1) IN153279B (no)
NO (1) NO151409C (no)
PH (1) PH17196A (no)
PL (1) PL130448B1 (no)
SU (1) SU993816A3 (no)
YU (1) YU42550B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
DE19529604A1 (de) * 1995-08-11 1997-02-13 Bayer Ag Endoparasitizide Mittel auf Basis von Didepsipeptiden, neue Didepsipeptide und ein Verfahren zu ihrer Herstellung
US9572856B2 (en) * 2009-12-16 2017-02-21 The George Washington University a Congressionally Chartered Not-for-Profit Corporation Method of treating low blood pressure
EP3858437A1 (en) 2013-04-26 2021-08-04 La Jolla Pharma, LLC Compositions and methods for treating renal failure
WO2015095535A1 (en) 2013-12-18 2015-06-25 The George Washington University, A Congressional Chartered Not-For-Profit Corporation Angiotensin ii alone or in combination for the treatment of hypotension
US10406201B2 (en) 2016-01-07 2019-09-10 La Jolla Pharma, Llc Methods for administering angiotensin II
WO2018191678A1 (en) 2017-04-14 2018-10-18 La Jolla Pharmaceutical Company Methods for administering angiotensin ii

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947575A (en) * 1969-06-30 1976-03-30 E. R. Squibb & Sons, Inc. Peptides as argiotensin converting enzyme inhibitors
DE2323322A1 (de) * 1973-05-09 1974-11-28 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3923770A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus {8 Me{hd 2{b Gly{hu 1{b , Ile{hu 8{b {9 -Anziotensin II as an angiotensin antagonist
US3923769A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus {8 N-Me-Ile{40 ,Ile{hu 8{b {9 -Angiotensin II as an angiotensin antagonist
US3915948A (en) * 1974-08-05 1975-10-28 Morton Norwich Products Inc Sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-proline
DE2457463A1 (de) * 1974-12-05 1976-06-10 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3975365A (en) * 1975-01-27 1976-08-17 G. D. Searle & Co. Inhibitory octapeptides angiotensin II
US3976770A (en) * 1975-02-10 1976-08-24 Francis Merlin Bumpus Sar'-(OMe)Thr8 Angiotensin II as an angiotensin II antagonist
HU177134B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity
HU177133B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha- amino-oxy-acid in position 1 with angiotensin ii antagonist activity

Also Published As

Publication number Publication date
JPS56142251A (en) 1981-11-06
AU541000B2 (en) 1984-12-13
CS219939B2 (en) 1983-03-25
PH17196A (en) 1984-06-19
PL229223A1 (no) 1982-03-01
SU993816A3 (ru) 1983-01-30
AU6627681A (en) 1981-07-23
NO151409B (no) 1984-12-27
ES498583A0 (es) 1981-12-01
DK149777C (da) 1987-04-21
US4330532A (en) 1982-05-18
FI73225C (fi) 1987-09-10
DE3160608D1 (en) 1983-08-25
EP0034260B1 (de) 1983-07-20
FI73225B (fi) 1987-05-29
IL61922A (en) 1984-01-31
IL61922A0 (en) 1981-02-27
EP0034260A1 (de) 1981-08-26
ATE4197T1 (de) 1983-08-15
NO151409C (no) 1985-04-10
CA1149377A (en) 1983-07-05
DK20481A (da) 1981-07-19
IN153279B (no) 1984-06-23
FI810123L (fi) 1981-07-19
PL130448B1 (en) 1984-08-31
HU181008B (en) 1983-05-30
YU42550B (en) 1988-10-31
ES8201129A1 (es) 1981-12-01
YU9381A (en) 1983-09-30
DK149777B (da) 1986-09-29

Similar Documents

Publication Publication Date Title
DE2801911A1 (de) (acyl-)-mercaptoacylaminosaeurederivate, verfahren zu deren herstellung und ihre verwendung bei der bekaempfung von durch angiotensin bedingtem hochdruck
KR860006488A (ko) 펩티다제 억제물의 제조방법
JPS574953A (en) Preparation of peptide amide sulfate ester terminated with cholecystokinin-pancreozymin c
NO810149L (no) Fremgangsmaate ved fremstilling av nye angiotensin-ii-analoger inneholdende en alfa-hydroxycarboxylsyrerest i 8-stilling
DK570682A (da) Fremgangsmaade til fremstilling af cycliske octapeptider eller salte eller komplekser deraf
JPS6136297A (ja) カルボキシアルキルジペプチドを製造する方法
HU896606D0 (en) Process for the preparation of aminoacid derivatives inhibiting enzymes and pharmaceutical compositions thereof
KR870002145A (ko) 아미노산 유도체의 제조방법
Anderson et al. [49] Preparation and use of glutathione monoesters
DE3165459D1 (en) Recovery of l-phenylalanine and l-aspartic acid during preparation of alpha-l-aspartyl-l-phenylalanine methyl ester
ATE85220T1 (de) Verfahren zur herstellung eines hochreinen, virusfreien antihaemophiliefaktors mittels chromatographie.
CA1331499C (en) Amino acids and peptides having a modified tyrosine residue, their preparation and their application as medicaments
EP0503044B1 (en) Peptide compounds of laevorotatory amino acids and ring molecules, and therapeutical applications thereof
ZA806328B (en) Method of using motility increasing peptides
GB986904A (en) Process for the production of peptides
Wallén et al. APPLICATION OF EDMAN PHENYLISOTHIOCYANATE METHOD IN THE DETERMINATION OF C-TERMINAL AMINO ACIDS AND PEPTIDES AFTER HYDRAZINOLYSIS
KR830007080A (ko) 무식욕유발성 펩티드류의 제조방법
GB1261673A (en) Antigen purification
Kovacs et al. Synthesis of optically active deuterium labelled serine and glycylserine derivatives
US3585180A (en) Process for preparing peptides containing histidine protected with a 2,2,2,-trihalogeno - n -benzyloxycarbonylaminoethyl group
JPS557221A (en) Preparation of alethine derivative
JPS5762245A (en) Novel preparation of cargtosin
SE194137C1 (no)
JPS5461170A (en) Preparation of coerulein and its analogs
IT8224313A1 (it) N-carbossialchiltioacil derivati di amminoacidi utili come antiipertensivi