ZA806328B - Method of using motility increasing peptides - Google Patents
Method of using motility increasing peptidesInfo
- Publication number
- ZA806328B ZA806328B ZA00806328A ZA806328A ZA806328B ZA 806328 B ZA806328 B ZA 806328B ZA 00806328 A ZA00806328 A ZA 00806328A ZA 806328 A ZA806328 A ZA 806328A ZA 806328 B ZA806328 B ZA 806328B
- Authority
- ZA
- South Africa
- Prior art keywords
- denotes
- amino acid
- alpha
- amino
- peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polyethers (AREA)
- Polyamides (AREA)
Abstract
1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, NL, SE The peptide of the formula I A-Tyr-B-C-D-E in which A denotes hydrogen, alkyl, alkenyl, or alkenylcycloalkyl each having up to 7 carbon atoms, an alpha-amino acid or a peptide with 2 or 3 amino acids, preferably of the L-configuration, B denotes an alpha-amino acid or alpha-amino-isobutyric acid, C denotes glycine or azaglycine, D denotes phenylalanine which can be substituted in the benzene nucleus by methyl, methoxy, halogen, nitro or trifluoromethyl, dehydro- or hexahydrophenylalanine, aza- or N-methylphenylalanine, and E denotes (a) -O-R1 R1 denotes a methyl-polyethylene glycol radical having a degree of polymerization of up to about 50, (b) an amino alcohol or an amino acid, which on its part may carry one of the groups defined sub (a). 1. Claims for the Contracting State : AT A process for the preparation of a peptide of the formula I A-Tyr-B-C-D-E in which A denotes hydrogen, alkyl, alkenyl, or alkenylcycloalkyl each having up to 7 carbon atoms, an alpha-amino acid or a peptide with 2 or 3 amino acids, preferably of the L-configuration, B denotes an alpha-amino acid or alpha-amino-isobutyric acid, C denotes glycine or azaglycine, D denotes phenylalanine which can be substituted in the benzene nucleus by methyl, methoxy, halogen, nitro or trifluormethyl, dehydro- or hexahydrophenylalanine, aza- or N-methylphenylalanine, and E denotes a) -O-R1 R1 denotes a methyl-polyethylene glycol radical having a degree of polymerization of up to about 50, b) an amino alcohol or an amino acid, which on its part may carry one of the groups defined sub (a), characterized in that the amino acid sequences of the formula I are prepared by methods of peptide synthesis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792941790 DE2941790A1 (en) | 1979-10-16 | 1979-10-16 | USE OF MOTIVITY-INCREASING PEPTIDES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA806328B true ZA806328B (en) | 1981-10-28 |
Family
ID=6083575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00806328A ZA806328B (en) | 1979-10-16 | 1980-10-15 | Method of using motility increasing peptides |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0028716B1 (en) |
| JP (1) | JPS5668617A (en) |
| AT (1) | ATE23441T1 (en) |
| AU (1) | AU541547B2 (en) |
| CA (1) | CA1177401A (en) |
| DE (2) | DE2941790A1 (en) |
| ZA (1) | ZA806328B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0044451B1 (en) * | 1980-07-17 | 1984-04-18 | Sandoz Ag | Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use |
| HU185640B (en) * | 1980-07-17 | 1985-03-28 | Sandoz Ag | Process for producing new pentapeptides |
| EP0076557B1 (en) * | 1981-06-22 | 1985-11-13 | Imperial Chemical Industries Plc | Peptides and pseudopeptides in which the n terminus bears two substituents |
| SU1470739A1 (en) * | 1984-07-16 | 1989-04-07 | Всесоюзный кардиологический научный центр АМН СССР | Hexapeptide displaying hepatoprotective traits |
| SU1348343A1 (en) * | 1984-07-16 | 1987-10-30 | Всесоюзный кардиологический научный центр АМН СССР | Hexapeptide possessing antipancreatonecrotic activity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2730851A1 (en) * | 1976-07-19 | 1978-01-26 | Sandoz Ag | NEW POLYPEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE |
| NO773013L (en) * | 1976-09-01 | 1978-03-02 | David Howard Coy | PROCEDURES FOR THE PREPARATION OF METHIONIN-ENKEFALIN DERIVATIVES |
-
1979
- 1979-10-16 DE DE19792941790 patent/DE2941790A1/en not_active Withdrawn
-
1980
- 1980-10-11 AT AT80106211T patent/ATE23441T1/en not_active IP Right Cessation
- 1980-10-11 EP EP80106211A patent/EP0028716B1/en not_active Expired
- 1980-10-11 DE DE8080106211T patent/DE3071825D1/en not_active Expired
- 1980-10-15 ZA ZA00806328A patent/ZA806328B/en unknown
- 1980-10-15 AU AU63284/80A patent/AU541547B2/en not_active Ceased
- 1980-10-15 CA CA000362430A patent/CA1177401A/en not_active Expired
- 1980-10-16 JP JP14373680A patent/JPS5668617A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU6328480A (en) | 1981-04-30 |
| DE2941790A1 (en) | 1981-04-30 |
| ATE23441T1 (en) | 1986-11-15 |
| EP0028716A2 (en) | 1981-05-20 |
| EP0028716A3 (en) | 1981-12-23 |
| DE3071825D1 (en) | 1987-01-02 |
| CA1177401A (en) | 1984-11-06 |
| JPS5668617A (en) | 1981-06-09 |
| EP0028716B1 (en) | 1986-11-12 |
| AU541547B2 (en) | 1985-01-10 |
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