AU541547B2 - Method of using motility increasing peptides - Google Patents
Method of using motility increasing peptidesInfo
- Publication number
- AU541547B2 AU541547B2 AU63284/80A AU6328480A AU541547B2 AU 541547 B2 AU541547 B2 AU 541547B2 AU 63284/80 A AU63284/80 A AU 63284/80A AU 6328480 A AU6328480 A AU 6328480A AU 541547 B2 AU541547 B2 AU 541547B2
- Authority
- AU
- Australia
- Prior art keywords
- denotes
- amino acid
- alpha
- amino
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Abstract
1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, NL, SE The peptide of the formula I A-Tyr-B-C-D-E in which A denotes hydrogen, alkyl, alkenyl, or alkenylcycloalkyl each having up to 7 carbon atoms, an alpha-amino acid or a peptide with 2 or 3 amino acids, preferably of the L-configuration, B denotes an alpha-amino acid or alpha-amino-isobutyric acid, C denotes glycine or azaglycine, D denotes phenylalanine which can be substituted in the benzene nucleus by methyl, methoxy, halogen, nitro or trifluoromethyl, dehydro- or hexahydrophenylalanine, aza- or N-methylphenylalanine, and E denotes (a) -O-R1 R1 denotes a methyl-polyethylene glycol radical having a degree of polymerization of up to about 50, (b) an amino alcohol or an amino acid, which on its part may carry one of the groups defined sub (a). 1. Claims for the Contracting State : AT A process for the preparation of a peptide of the formula I A-Tyr-B-C-D-E in which A denotes hydrogen, alkyl, alkenyl, or alkenylcycloalkyl each having up to 7 carbon atoms, an alpha-amino acid or a peptide with 2 or 3 amino acids, preferably of the L-configuration, B denotes an alpha-amino acid or alpha-amino-isobutyric acid, C denotes glycine or azaglycine, D denotes phenylalanine which can be substituted in the benzene nucleus by methyl, methoxy, halogen, nitro or trifluormethyl, dehydro- or hexahydrophenylalanine, aza- or N-methylphenylalanine, and E denotes a) -O-R1 R1 denotes a methyl-polyethylene glycol radical having a degree of polymerization of up to about 50, b) an amino alcohol or an amino acid, which on its part may carry one of the groups defined sub (a), characterized in that the amino acid sequences of the formula I are prepared by methods of peptide synthesis.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792941790 DE2941790A1 (en) | 1979-10-16 | 1979-10-16 | USE OF MOTIVITY-INCREASING PEPTIDES |
| DE29417901 | 1979-10-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU6328480A AU6328480A (en) | 1981-04-30 |
| AU541547B2 true AU541547B2 (en) | 1985-01-10 |
Family
ID=6083575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU63284/80A Ceased AU541547B2 (en) | 1979-10-16 | 1980-10-15 | Method of using motility increasing peptides |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0028716B1 (en) |
| JP (1) | JPS5668617A (en) |
| AT (1) | ATE23441T1 (en) |
| AU (1) | AU541547B2 (en) |
| CA (1) | CA1177401A (en) |
| DE (2) | DE2941790A1 (en) |
| ZA (1) | ZA806328B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5756447A (en) * | 1980-07-17 | 1982-04-05 | Sandoz Ag | Novel pentapeptides |
| DE3163199D1 (en) * | 1980-07-17 | 1984-05-24 | Sandoz Ag | Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use |
| DE3267380D1 (en) * | 1981-06-22 | 1985-12-19 | Ici Plc | Peptides and pseudopeptides in which the n terminus bears two substituents |
| SU1348343A1 (en) * | 1984-07-16 | 1987-10-30 | Всесоюзный кардиологический научный центр АМН СССР | Hexapeptide possessing antipancreatonecrotic activity |
| SU1470739A1 (en) * | 1984-07-16 | 1989-04-07 | Всесоюзный кардиологический научный центр АМН СССР | Hexapeptide displaying hepatoprotective traits |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2730851A1 (en) * | 1976-07-19 | 1978-01-26 | Sandoz Ag | NEW POLYPEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE |
| NO773013L (en) * | 1976-09-01 | 1978-03-02 | David Howard Coy | PROCEDURES FOR THE PREPARATION OF METHIONIN-ENKEFALIN DERIVATIVES |
-
1979
- 1979-10-16 DE DE19792941790 patent/DE2941790A1/en not_active Withdrawn
-
1980
- 1980-10-11 EP EP80106211A patent/EP0028716B1/en not_active Expired
- 1980-10-11 DE DE8080106211T patent/DE3071825D1/en not_active Expired
- 1980-10-11 AT AT80106211T patent/ATE23441T1/en not_active IP Right Cessation
- 1980-10-15 CA CA000362430A patent/CA1177401A/en not_active Expired
- 1980-10-15 AU AU63284/80A patent/AU541547B2/en not_active Ceased
- 1980-10-15 ZA ZA00806328A patent/ZA806328B/en unknown
- 1980-10-16 JP JP14373680A patent/JPS5668617A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA1177401A (en) | 1984-11-06 |
| ZA806328B (en) | 1981-10-28 |
| EP0028716B1 (en) | 1986-11-12 |
| EP0028716A2 (en) | 1981-05-20 |
| AU6328480A (en) | 1981-04-30 |
| DE2941790A1 (en) | 1981-04-30 |
| DE3071825D1 (en) | 1987-01-02 |
| JPS5668617A (en) | 1981-06-09 |
| ATE23441T1 (en) | 1986-11-15 |
| EP0028716A3 (en) | 1981-12-23 |
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