AU541547B2 - Method of using motility increasing peptides - Google Patents

Method of using motility increasing peptides

Info

Publication number
AU541547B2
AU541547B2 AU63284/80A AU6328480A AU541547B2 AU 541547 B2 AU541547 B2 AU 541547B2 AU 63284/80 A AU63284/80 A AU 63284/80A AU 6328480 A AU6328480 A AU 6328480A AU 541547 B2 AU541547 B2 AU 541547B2
Authority
AU
Australia
Prior art keywords
denotes
amino acid
alpha
amino
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU63284/80A
Other versions
AU6328480A (en
Inventor
Martin Bickel
Rolf Geiger
Rainer Obermeier
Volker Teetz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU6328480A publication Critical patent/AU6328480A/en
Application granted granted Critical
Publication of AU541547B2 publication Critical patent/AU541547B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyethers (AREA)
  • Polyamides (AREA)

Abstract

1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, NL, SE The peptide of the formula I A-Tyr-B-C-D-E in which A denotes hydrogen, alkyl, alkenyl, or alkenylcycloalkyl each having up to 7 carbon atoms, an alpha-amino acid or a peptide with 2 or 3 amino acids, preferably of the L-configuration, B denotes an alpha-amino acid or alpha-amino-isobutyric acid, C denotes glycine or azaglycine, D denotes phenylalanine which can be substituted in the benzene nucleus by methyl, methoxy, halogen, nitro or trifluoromethyl, dehydro- or hexahydrophenylalanine, aza- or N-methylphenylalanine, and E denotes (a) -O-R1 R1 denotes a methyl-polyethylene glycol radical having a degree of polymerization of up to about 50, (b) an amino alcohol or an amino acid, which on its part may carry one of the groups defined sub (a). 1. Claims for the Contracting State : AT A process for the preparation of a peptide of the formula I A-Tyr-B-C-D-E in which A denotes hydrogen, alkyl, alkenyl, or alkenylcycloalkyl each having up to 7 carbon atoms, an alpha-amino acid or a peptide with 2 or 3 amino acids, preferably of the L-configuration, B denotes an alpha-amino acid or alpha-amino-isobutyric acid, C denotes glycine or azaglycine, D denotes phenylalanine which can be substituted in the benzene nucleus by methyl, methoxy, halogen, nitro or trifluormethyl, dehydro- or hexahydrophenylalanine, aza- or N-methylphenylalanine, and E denotes a) -O-R1 R1 denotes a methyl-polyethylene glycol radical having a degree of polymerization of up to about 50, b) an amino alcohol or an amino acid, which on its part may carry one of the groups defined sub (a), characterized in that the amino acid sequences of the formula I are prepared by methods of peptide synthesis.
AU63284/80A 1979-10-16 1980-10-15 Method of using motility increasing peptides Ceased AU541547B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE29417901 1979-10-16
DE19792941790 DE2941790A1 (en) 1979-10-16 1979-10-16 USE OF MOTIVITY-INCREASING PEPTIDES

Publications (2)

Publication Number Publication Date
AU6328480A AU6328480A (en) 1981-04-30
AU541547B2 true AU541547B2 (en) 1985-01-10

Family

ID=6083575

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63284/80A Ceased AU541547B2 (en) 1979-10-16 1980-10-15 Method of using motility increasing peptides

Country Status (7)

Country Link
EP (1) EP0028716B1 (en)
JP (1) JPS5668617A (en)
AT (1) ATE23441T1 (en)
AU (1) AU541547B2 (en)
CA (1) CA1177401A (en)
DE (2) DE2941790A1 (en)
ZA (1) ZA806328B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3163199D1 (en) * 1980-07-17 1984-05-24 Sandoz Ag Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
JPS5756447A (en) * 1980-07-17 1982-04-05 Sandoz Ag Novel pentapeptides
EP0076557B1 (en) * 1981-06-22 1985-11-13 Imperial Chemical Industries Plc Peptides and pseudopeptides in which the n terminus bears two substituents
SU1470739A1 (en) * 1984-07-16 1989-04-07 Всесоюзный кардиологический научный центр АМН СССР Hexapeptide displaying hepatoprotective traits
SU1348343A1 (en) * 1984-07-16 1987-10-30 Всесоюзный кардиологический научный центр АМН СССР Hexapeptide possessing antipancreatonecrotic activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2730851A1 (en) * 1976-07-19 1978-01-26 Sandoz Ag NEW POLYPEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE
SE7709806L (en) * 1976-09-01 1978-03-02 Coy David Howard PROCEDURE FOR PREPARING PEPTIDES

Also Published As

Publication number Publication date
ZA806328B (en) 1981-10-28
ATE23441T1 (en) 1986-11-15
EP0028716A2 (en) 1981-05-20
DE2941790A1 (en) 1981-04-30
DE3071825D1 (en) 1987-01-02
CA1177401A (en) 1984-11-06
AU6328480A (en) 1981-04-30
JPS5668617A (en) 1981-06-09
EP0028716A3 (en) 1981-12-23
EP0028716B1 (en) 1986-11-12

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