IL29324A - New esters of 5-nitroimidazole-2-carboxylic acids and the process for their preparation - Google Patents
New esters of 5-nitroimidazole-2-carboxylic acids and the process for their preparationInfo
- Publication number
- IL29324A IL29324A IL2932464A IL2932464A IL29324A IL 29324 A IL29324 A IL 29324A IL 2932464 A IL2932464 A IL 2932464A IL 2932464 A IL2932464 A IL 2932464A IL 29324 A IL29324 A IL 29324A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- nitroimidazole
- esters
- formula
- ethyl
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title claims description 11
- 238000000034 method Methods 0.000 title claims description 7
- 238000002360 preparation method Methods 0.000 title claims description 7
- LNPSXTPPQBEISL-UHFFFAOYSA-N 5-nitro-1h-imidazole-2-carboxylic acid Chemical class OC(=O)C1=NC=C([N+]([O-])=O)N1 LNPSXTPPQBEISL-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 claims description 6
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 5
- 150000007513 acids Chemical class 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 3
- 239000011707 mineral Substances 0.000 claims description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- YZEUHQHUFTYLPH-UHFFFAOYSA-N 2-nitroimidazole Chemical compound [O-][N+](=O)C1=NC=CN1 YZEUHQHUFTYLPH-UHFFFAOYSA-N 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 description 5
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 2
- -1 methyl ethyl Chemical group 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012259 ether extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000004957 nitroimidazoles Chemical class 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Basic Packing Technique (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30067563A | 1963-08-07 | 1963-08-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL29324A true IL29324A (en) | 1968-08-22 |
Family
ID=23160128
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL2932464A IL29324A (en) | 1963-08-07 | 1964-07-24 | New esters of 5-nitroimidazole-2-carboxylic acids and the process for their preparation |
| IL2175864A IL21758A (en) | 1963-08-07 | 1964-07-24 | Imidazole compounds and methods of preparing them |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL2175864A IL21758A (en) | 1963-08-07 | 1964-07-24 | Imidazole compounds and methods of preparing them |
Country Status (11)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3676439A (en) * | 1971-04-13 | 1972-07-11 | Hoffmann La Roche | 5,6-dihydro-8,8-dimethyl-3-nitro-8h imidazo(2-1-c) (1,4)oxazine |
| DE102022003986A1 (de) | 2021-10-01 | 2023-04-06 | Tobias Schmallenbach | Multifunktionale Tasche |
-
0
- NL NL139524D patent/NL139524A/xx unknown
-
1964
- 1964-07-24 IL IL2932464A patent/IL29324A/en unknown
- 1964-07-24 IL IL2175864A patent/IL21758A/xx unknown
- 1964-08-04 GB GB3156964A patent/GB1077692A/en not_active Expired
- 1964-08-04 GB GB3577766A patent/GB1077696A/en not_active Expired
- 1964-08-05 DK DK492365A patent/DK108229C/da active
- 1964-08-05 DK DK387064A patent/DK108499C/da active
- 1964-08-05 BE BE651423D patent/BE651423A/xx unknown
- 1964-08-05 DK DK492465A patent/DK108153C/da active
- 1964-08-05 DK DK492265A patent/DK109264C/da active
- 1964-08-06 BR BR16152764A patent/BR6461527D0/pt unknown
- 1964-08-06 FR FR1583154D patent/FR1583154A/fr not_active Expired
- 1964-08-06 SE SE955264A patent/SE325273B/xx unknown
- 1964-08-06 DE DE19641470080 patent/DE1470080A1/de active Pending
- 1964-08-06 NO NO15428564A patent/NO116163B/no unknown
- 1964-08-07 NL NL6409120A patent/NL139524B/xx unknown
- 1964-08-07 CH CH1035764A patent/CH467266A/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1077692A (en) | 1967-08-02 |
| FR1583154A (enrdf_load_stackoverflow) | 1969-10-24 |
| NO116163B (enrdf_load_stackoverflow) | 1969-02-10 |
| NL6409120A (enrdf_load_stackoverflow) | 1965-02-08 |
| DE1470080A1 (de) | 1970-01-02 |
| DK108229C (da) | 1967-10-23 |
| NL139524B (nl) | 1973-08-15 |
| DK108153C (da) | 1967-09-25 |
| IL21758A (en) | 1968-08-22 |
| CH467266A (de) | 1969-01-15 |
| NL139524A (enrdf_load_stackoverflow) | |
| BR6461527D0 (pt) | 1973-07-17 |
| SE325273B (enrdf_load_stackoverflow) | 1970-06-29 |
| BE651423A (enrdf_load_stackoverflow) | 1965-02-05 |
| DK109264C (da) | 1968-04-08 |
| DK108499C (da) | 1967-12-27 |
| GB1077696A (en) | 1967-08-02 |
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