JPS5418330B2
(hr)
*
|
1973-03-16 |
1979-07-06 |
|
|
US3966905A
(en)
*
|
1973-05-29 |
1976-06-29 |
Barnes-Hind Pharmaceuticals, Inc. |
Stabilized catechol amine solutions
|
US3929989A
(en)
*
|
1974-06-14 |
1975-12-30 |
Wendt Lab Inc |
Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
|
GB1538903A
(en)
*
|
1975-04-11 |
1979-01-24 |
Nelson Res & Dev |
Carrier for a topically applied physiologically active agent or cosmetic agent
|
US4018889A
(en)
*
|
1976-01-02 |
1977-04-19 |
Pfizer Inc. |
Oxytetracycline compositions
|
DE2602363C2
(de)
*
|
1976-01-22 |
1984-04-12 |
Bayer Ag, 5090 Leverkusen |
Wäßrige, injizierbare Niclofolan- Formulierungen
|
GB1592053A
(en)
*
|
1976-12-16 |
1981-07-01 |
Norbrook Lab Ltd |
Oxytetracycline compositions
|
US4213963A
(en)
*
|
1978-12-14 |
1980-07-22 |
Janssen Pharmaceutica N.V. |
Fluspirilene-containing compositions
|
US4259331A
(en)
*
|
1979-04-16 |
1981-03-31 |
Pfizer Inc. |
Oxytetracycline compositions
|
US4386083A
(en)
*
|
1980-04-10 |
1983-05-31 |
Walter Hacke |
Injectable oxytetracycline compositions
|
US4399127A
(en)
*
|
1980-04-10 |
1983-08-16 |
Diamond Shamrock Corporation |
Injectable oxytetracycline compositions
|
IE74244B1
(en)
*
|
1985-10-01 |
1997-07-16 |
Bimeda Res Dev Ltd |
A process for preparing an antibiotic composition
|
US5071643A
(en)
*
|
1986-10-17 |
1991-12-10 |
R. P. Scherer Corporation |
Solvent system enhancing the solubility of pharmaceuticals for encapsulation
|
US6756365B2
(en)
*
|
1991-11-06 |
2004-06-29 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
EP0626171A1
(de)
*
|
1993-05-26 |
1994-11-30 |
Winfried Dörnhöfer |
Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
|
US6383515B2
(en)
|
1999-05-28 |
2002-05-07 |
Sawyer Maryjean |
Solvent system for enhancing solubility
|
US8106225B2
(en)
*
|
1999-09-14 |
2012-01-31 |
Trustees Of Tufts College |
Methods of preparing substituted tetracyclines with transition metal-based chemistries
|
US6849615B2
(en)
|
1999-09-14 |
2005-02-01 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
US6500812B2
(en)
|
1999-09-14 |
2002-12-31 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
DE60027465T2
(de)
|
1999-09-14 |
2007-02-01 |
The Trustees Of Tufts College, Medford |
Verfahren zur herstellung von substituierten tetracyclinen mit hilfe von auf übergangsmetalle basierten chemien
|
WO2001052858A1
(en)
*
|
2000-01-24 |
2001-07-26 |
Trustees Of Tufts College |
Tetracycline compounds for treatment of cryptosporidium parvum related disorders
|
MXPA02009482A
(es)
|
2000-03-31 |
2004-05-14 |
Tufts College |
Compuestos tetraciclinas sustituidos con grupos 7- y 9- carbamato, urea, tiourea, tiocarbamato y heteroaril-amino.
|
AU2001259701A1
(en)
|
2000-05-15 |
2001-11-26 |
Paratek Pharmaceuticals, Inc |
7-substituted fused ring tetracycline compounds
|
US20020132798A1
(en)
*
|
2000-06-16 |
2002-09-19 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
US20040224927A1
(en)
|
2000-06-16 |
2004-11-11 |
Trustees Of Tufts College |
7-N-substituted phenyl tetracycline compounds
|
AU2001268475A1
(en)
*
|
2000-06-16 |
2002-01-02 |
Trustees Of Tufts College |
7-phenyl-substituted tetracycline compounds
|
US6846939B2
(en)
*
|
2000-07-07 |
2005-01-25 |
Paratek Pharmaceuticals, Inc. |
9-substituted minocycline compounds
|
US7094806B2
(en)
|
2000-07-07 |
2006-08-22 |
Trustees Of Tufts College |
7, 8 and 9-substituted tetracycline compounds
|
US20050143353A1
(en)
*
|
2000-07-07 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
13-Substituted methacycline compounds
|
WO2002004404A2
(en)
|
2000-07-07 |
2002-01-17 |
Trustees Of Tufts College |
7,8 and 9-substituted tetracycline compounds
|
DE60141994D1
(de)
|
2000-07-07 |
2010-06-10 |
Tufts College |
13-substituierte Methacyclinverbindungen
|
CA2415718C
(en)
|
2000-07-07 |
2012-08-28 |
Trustees Of Tufts College |
7-substituted tetracycline compounds
|
BR0116935A
(pt)
|
2001-03-13 |
2005-04-12 |
Paratek Pharm Innc |
Composto de tetraciclina, método para tratar um estado responsivo à tetraciclina em um indivìduo, e, composição farmacêutica
|
WO2002072506A2
(en)
*
|
2001-03-13 |
2002-09-19 |
Paratek Pharmaceuticals, Inc. |
7-pyrollyl tetracycline compounds and methods of use thereof
|
US6841546B2
(en)
|
2001-03-14 |
2005-01-11 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as antifungal agents
|
WO2002072031A2
(en)
|
2001-03-14 |
2002-09-19 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as synergistic antifungal agents
|
ATE455092T1
(de)
|
2001-04-24 |
2010-01-15 |
Paratek Pharm Innc |
Substituierte tetracyclin-verbindungen zur behandlung von malaria
|
US8088820B2
(en)
*
|
2001-04-24 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
EP2311796A1
(en)
|
2002-01-08 |
2011-04-20 |
Paratek Pharmaceuticals, Inc. |
4-dedimethylamino tetracycline compounds
|
AU2003220123B2
(en)
|
2002-03-08 |
2009-05-07 |
Paratek Pharmaceuticals, Inc. |
Amino-methyl substituted tetracycline compounds
|
WO2003079984A2
(en)
|
2002-03-21 |
2003-10-02 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
WO2004006850A2
(en)
|
2002-07-12 |
2004-01-22 |
Paratek Pharmaceuticals, Inc |
3, 10, AND 12a SUBSTITUTED TETRACYCLINE COMPOUNDS
|
EP2277504A1
(en)
|
2002-10-24 |
2011-01-26 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
EP1605916A4
(en)
*
|
2003-02-12 |
2012-02-22 |
R & P Korea Co Ltd |
SOLUBENT SOLVENT SYSTEM WITH SOLUBLE PEEL WITH IMPROVED ELUTION RATE
|
JP4738333B2
(ja)
|
2003-07-09 |
2011-08-03 |
パラテック ファーマシューティカルズ インコーポレイテッド |
9−アミノメチルテトラサイクリン化合物のプロドラッグ
|
US20060287283A1
(en)
*
|
2003-07-09 |
2006-12-21 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
CN101786991A
(zh)
|
2003-07-09 |
2010-07-28 |
帕拉特克药品公司 |
取代的四环素化合物
|
JP5010284B2
(ja)
|
2004-01-15 |
2012-08-29 |
パラテック ファーマシューティカルズ インコーポレイテッド |
テトラサイクリン化合物の芳香族a環誘導体
|
TWI261038B
(en)
*
|
2004-08-11 |
2006-09-01 |
Bo-Cheng Chen |
Bicycle gear-shifting handgrip
|
EP2284150A3
(en)
|
2004-10-25 |
2011-09-21 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
AU2005299294B2
(en)
|
2004-10-25 |
2012-06-07 |
Paratek Pharmaceuticals, Inc. |
4-aminotetracyclines and methods of use thereof
|
US8088755B2
(en)
|
2005-02-04 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
11a, 12-derivatives of tetracycline compounds
|
DE102005012595A1
(de)
*
|
2005-03-18 |
2006-09-21 |
Lanxess Deutschland Gmbh |
Herstellung von Tri(chlorpropyl)phosphat
|
WO2007014154A2
(en)
*
|
2005-07-21 |
2007-02-01 |
Paratek Pharmaceuticals, Inc. |
10-substituted tetracyclines and methods of use thereof
|
JP2009508951A
(ja)
*
|
2005-09-19 |
2009-03-05 |
アルベマール・コーポレーシヨン |
カリウムイブプロフェンの極めて濃厚な注入可能な水溶液、その製造法および使用
|
WO2007087416A2
(en)
|
2006-01-24 |
2007-08-02 |
Paratek Pharaceuticals, Inc. |
Methods of increasing oral bioavailability of tetracyclines
|
WO2007120913A2
(en)
*
|
2006-04-17 |
2007-10-25 |
Teva Pharmaceutical Industries Ltd. |
Isolation of tetracycline derivatives
|
EP2016045B1
(en)
*
|
2006-04-24 |
2014-10-29 |
Teva Pharmaceutical Industries, Ltd. |
A tigecycline crystalline form and processes for its preparation
|
US8198470B2
(en)
*
|
2006-04-24 |
2012-06-12 |
Teva Pharmaceutical Industries Ltd. |
Crystalline form II of tigecycline and processes for preparation thereof
|
EP2026776A2
(en)
*
|
2006-05-15 |
2009-02-25 |
Paratek Pharmaceuticals, Inc. |
Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
|
US8440646B1
(en)
|
2006-10-11 |
2013-05-14 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of Bacillus anthracis infections
|
PT2120963T
(pt)
|
2006-12-21 |
2018-12-17 |
Paratek Pharm Innc |
Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
|
ES2463457T3
(es)
|
2006-12-21 |
2014-05-28 |
Paratek Pharmaceuticals, Inc. |
Derivados de la tetraciclina para el tratamiento de infecciones bacterianas, virales y parasitarias
|
EP2144614A1
(en)
*
|
2007-04-12 |
2010-01-20 |
Paratek Pharmaceuticals, Inc. |
Methods for treating spinal muscular atrophy using tetracycline compounds
|
CA2688662A1
(en)
|
2007-04-27 |
2008-11-06 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing and purifying aminoalkyl tetracycline compounds
|
ES2386926T3
(es)
|
2007-07-06 |
2012-09-06 |
Paratek Pharmaceuticals, Inc. |
Métodos para sintetizar minociclina9-sustituida
|
WO2009111064A2
(en)
|
2008-03-05 |
2009-09-11 |
Paratek Pharmaceuticals, Inc. |
Minocycline compounds and methods of use thereof
|
PT2271348T
(pt)
|
2008-03-28 |
2018-04-16 |
Paratek Pharm Innc |
Formulação de comprimido oral de composto de tetraciclina
|
US20100022483A1
(en)
*
|
2008-04-14 |
2010-01-28 |
Paratek Pharmaceuticals, Inc. |
Substituted Tetracycline Compounds
|
TW202332671A
(zh)
*
|
2008-05-23 |
2023-08-16 |
美商Prtk Spv2公司 |
四環素化合物之甲苯磺酸鹽及同素異形體
|
US9629809B2
(en)
|
2008-07-21 |
2017-04-25 |
Si Group, Inc. |
High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
|
WO2010011522A1
(en)
|
2008-07-21 |
2010-01-28 |
Albemarle Corporation |
High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
|
AP2011005631A0
(en)
*
|
2008-09-19 |
2011-04-30 |
Paratek Pharmaceuticals Ind |
Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment.
|
AU2010233089B2
(en)
|
2009-04-10 |
2016-05-26 |
Tufts Medical Center, Inc. |
Par-1 activation by metalloproteinase-1 (MMP-1)
|
CA2835876C
(en)
|
2011-05-12 |
2020-04-14 |
Paratek Pharmaceuticals, Inc. |
Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same
|
SG10201913599RA
(en)
|
2016-11-01 |
2020-02-27 |
Paratek Pharm Innc |
9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
|
EP3654988B1
(en)
|
2017-07-21 |
2023-09-06 |
Almirall, LLC |
Sarecycline for the treatment of non-inflammatory acne lesions
|