IL255605B - Antifungal compounds - Google Patents
Antifungal compoundsInfo
- Publication number
- IL255605B IL255605B IL255605A IL25560517A IL255605B IL 255605 B IL255605 B IL 255605B IL 255605 A IL255605 A IL 255605A IL 25560517 A IL25560517 A IL 25560517A IL 255605 B IL255605 B IL 255605B
- Authority
- IL
- Israel
- Prior art keywords
- antifungal compounds
- antifungal
- compounds
- Prior art date
Links
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562163106P | 2015-05-18 | 2015-05-18 | |
| PCT/US2016/032877 WO2016187201A2 (en) | 2015-05-18 | 2016-05-17 | Antifungal compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL255605A IL255605A (en) | 2018-01-31 |
| IL255605B true IL255605B (en) | 2021-03-25 |
Family
ID=57320616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL255605A IL255605B (en) | 2015-05-18 | 2017-11-12 | Antifungal compounds |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US11051514B2 (enExample) |
| EP (2) | EP3702353B1 (enExample) |
| JP (1) | JP6908533B2 (enExample) |
| KR (1) | KR20180000731A (enExample) |
| CN (1) | CN107750248A (enExample) |
| AR (1) | AR104695A1 (enExample) |
| AU (2) | AU2016265932B2 (enExample) |
| BR (1) | BR112017024463B1 (enExample) |
| CA (1) | CA2986041C (enExample) |
| CL (1) | CL2017002929A1 (enExample) |
| CO (1) | CO2017012621A2 (enExample) |
| CR (1) | CR20170574A (enExample) |
| DK (1) | DK3297998T3 (enExample) |
| EA (1) | EA034387B1 (enExample) |
| EC (1) | ECSP17082683A (enExample) |
| ES (1) | ES2776241T3 (enExample) |
| HK (2) | HK1251569A1 (enExample) |
| IL (1) | IL255605B (enExample) |
| LT (1) | LT3297998T (enExample) |
| MX (1) | MX378499B (enExample) |
| PH (1) | PH12017502082B1 (enExample) |
| TW (1) | TWI623527B (enExample) |
| UA (1) | UA120784C2 (enExample) |
| WO (1) | WO2016187201A2 (enExample) |
| ZA (1) | ZA201707783B (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015143162A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| MX2016012060A (es) * | 2014-03-19 | 2017-01-19 | Viamet Pharmaceuticals Inc | 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procesos para su preparacion. |
| WO2015143154A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| US10017494B2 (en) | 2014-03-19 | 2018-07-10 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
| EP3119754A4 (en) | 2014-03-19 | 2017-12-13 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| JP2017509646A (ja) | 2014-03-19 | 2017-04-06 | ヴィアメット ファーマスーティカルズ，インコーポレイテッド | 抗真菌化合物の調製方法 |
| BR112016021257B1 (pt) | 2014-03-19 | 2021-03-02 | Viamet Pharmaceuticals (NC), Inc. | 2-(2,4- difluorofenil-1,1-diflúor-1-(5-substituído-piridin-2-il)-3- (1h-tetrazol-1-il)propan-2-óis e processos para preparação e uso dos mesmos |
| WO2015143166A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| EP3119745B1 (en) | 2014-03-19 | 2020-08-05 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
| RU2708392C2 (ru) | 2014-12-30 | 2019-12-06 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Соединения пиколинамида с фунгицидной активностью |
| WO2017049096A1 (en) | 2015-09-18 | 2017-03-23 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| KR20180100313A (ko) * | 2015-11-17 | 2018-09-10 | 다우 아그로사이언시즈 엘엘씨 | 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-히드록시-3-(1h-1,2,4-트리아졸-1-일)프로필)피리딘-3-일)옥시)벤조니트릴 및 제조방법 |
| EP3377475A4 (en) * | 2015-11-17 | 2019-04-10 | Dow Agrosciences Llc | 4 - ((6-2- (2,4-difluorophenyl) -1,1-difluoro-2-hydroxy-3- (1H-1,2,4-triazol-1-YL) PROPYL) PYRIDINE-3-YL ) OXY) BENZONITRIL AND METHOD OF PREPARING THEREOF |
| KR20180101343A (ko) * | 2015-11-17 | 2018-09-12 | 다우 아그로사이언시즈 엘엘씨 | 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-옥소에틸)피리딘-3-일)옥시)벤조니트릴 및 제조방법 |
| BR112018009920A2 (pt) * | 2015-11-17 | 2018-11-13 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorfenil)-1,1-diflúor-2-hidróxi-3-(1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| US20190284161A1 (en) * | 2016-11-18 | 2019-09-19 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
| BR112019009759A2 (pt) * | 2016-11-18 | 2019-08-13 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| EP3555047A4 (en) * | 2016-11-18 | 2020-04-29 | Dow AgroSciences LLC | T-BUTYL-2-CARBAMOTHIOYL-2- (3- (5- (4-CYANOPHENOXY) PYRIDIN-2-YL) -2- (2,4-DIFLUORPHENYL) -3,3-DIFLUOR-2-HYDROXYPROPYL) HYDRAZIN- 1-CARBOXYLATE AND PRODUCTION METHOD |
| BR112019009812A2 (pt) * | 2016-11-18 | 2019-08-13 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| US20190284159A1 (en) * | 2016-11-18 | 2019-09-19 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
| CN109983005A (zh) * | 2016-11-18 | 2019-07-05 | 美国陶氏益农公司 | 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法 |
| BR112019009787A2 (pt) * | 2016-11-18 | 2019-08-06 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro -2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil) piridina-3-il)óxi)benzonitrila e processos de preparação |
| US20190330184A1 (en) * | 2016-11-18 | 2019-10-31 | Dow Agrosciences Llc | 4-((6-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
| BR112019009801A2 (pt) * | 2016-11-18 | 2019-08-06 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorofenil)-1,1-difluoro-2-hidróxi-3-(5-mercapto-1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| MA46135B2 (fr) * | 2016-11-22 | 2021-01-29 | Dow Agrosciences Llc | Composés et mélanges fongicides pour la lutte contre les maladies fongiques dans des céréales |
| EP3544429A4 (en) * | 2016-11-22 | 2020-04-29 | Dow Agrosciences Llc | USE OF A DIFLUORO- (2-HYDROXYPROPYL) PYRIDINE COMPOUND AS A FUNGICIDE FOR THE CONTROL OF WHEAT PHYTOPATHOGENIC FUNGI |
| AR110209A1 (es) * | 2016-11-22 | 2019-03-06 | Viamet Pharmaceuticals Inc | Uso de un compuesto de difluoro-(2-hidroxipropil)piridina como fungicida para el control de hongos fitopatógenos en maíz |
| JP2019535752A (ja) * | 2016-11-22 | 2019-12-12 | ダウ アグロサイエンシィズ エルエルシー | テンサイの斑点病の防除のための殺真菌剤としてのジフルオロ−（２−ヒドロキシプロピル）ピリジン化合物の使用 |
| CA3044340A1 (en) * | 2016-11-22 | 2018-05-31 | Dow Agrosciences Llc | Fungicidal compounds and mixtures for fungal control in cereals |
| BR112019010142A2 (pt) * | 2016-11-22 | 2019-09-17 | Dow Agrosciences Llc | compostos de fungicida e misturas para controle fúngico em cereais |
| AR110214A1 (es) * | 2016-11-22 | 2019-03-06 | Viamet Pharmaceuticals Inc | Compuestos y mezclas fungicidas para el control de hongos en cereales |
| WO2018098256A1 (en) * | 2016-11-22 | 2018-05-31 | Vps-3, Inc. | Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of rice |
| RU2749224C2 (ru) * | 2016-11-22 | 2021-06-07 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Фунгицидные соединения и смеси для борьбы с грибковыми заболеваниями зерновых культур |
| EP3544434A4 (en) * | 2016-11-22 | 2020-04-15 | Dow AgroSciences LLC | USE OF A DIFLUORO- (2-HYDROXYPROPYL) PYRIDINE COMPOUND AS A FUNGICIDE FOR THE CONTROL OF PHYTOPATHOGENIC BARLEY FUNGI |
| TW201842851A (zh) * | 2017-05-02 | 2018-12-16 | 美商陶氏農業科學公司 | 用於穀類中的真菌防治之協同性混合物 |
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| WO2020020813A1 (en) | 2018-07-25 | 2020-01-30 | Bayer Aktiengesellschaft | Fungicidal active compound combinations |
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| WO2020037109A1 (en) * | 2018-08-17 | 2020-02-20 | Dow Agrosciences Llc | Processes for fluorination |
| BR112021006045A2 (pt) | 2018-10-19 | 2021-06-29 | Basf Se | misturas fungicidas, composição pesticida, uso da mistura e método para o combate de parasitas fitopatogênicos |
| BR112021006011A2 (pt) | 2018-10-19 | 2021-06-29 | Basf Se | misturas fungicidas, composição pesticida, uso da mistura e método para controlar pragas fitopatogênicas |
| BR112021015521A2 (pt) | 2019-02-20 | 2021-10-05 | Basf Se | Misturas de pesticidas, método para controlar fungos nocivos fitopatogênicos e método para proteger plantas em crescimento ou materiais de propagação de plantas do ataque ou infestação por pragas invertebradas |
| PH12021552149A1 (en) * | 2019-03-06 | 2024-04-22 | Corteva Agriscience Llc | A difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for black sigatoka |
| EP4044811A4 (en) | 2019-10-18 | 2023-09-27 | Corteva Agriscience LLC | METHOD FOR SYNTHESIS OF PICOLINAMIDS |
| WO2021104910A1 (en) * | 2019-11-26 | 2021-06-03 | Basf Se | Method to control septoria tritici resistant to c14-demethylase inhibitor fungicides |
| EP4331364A3 (en) | 2020-02-04 | 2024-05-15 | Corteva Agriscience LLC | Compositions having pesticidal utility and processes related thereto |
| CN115315186A (zh) | 2020-03-13 | 2022-11-08 | 先正达农作物保护股份公司 | 控制或预防植物被植物病原性微生物多主棒孢菌侵染的方法 |
| BR112022018295A2 (pt) | 2020-03-13 | 2022-10-25 | Syngenta Crop Protection Ag | Métodos de controle ou prevenção de infestação de plantas pelo microrganismo fitopatogênico corynespora cassiicola, cercospora sojina e/ou cercospora kikuchii |
| BR112022018267A2 (pt) | 2020-03-13 | 2022-10-25 | Syngenta Crop Protection Ag | Métodos de controle ou prevenção de infestação de plantas pelo microrganismo fitopatogênico corynespora cassiicola |
| BR112022019796A2 (pt) | 2020-04-01 | 2022-11-16 | Basf Se | Misturas fungicidas, composição pesticida, uso da mistura e método para controlar pragas fitopatogênicas |
| BR112022019582A2 (pt) | 2020-04-01 | 2022-11-16 | Basf Se | Misturas fungicidas, composição pesticida, uso da mistura e método para controlar pragas fitopatogênicas |
| BR112023006280A2 (pt) | 2020-10-05 | 2023-05-09 | Syngenta Crop Protection Ag | Composições fungicidas |
| WO2022090069A1 (en) | 2020-11-02 | 2022-05-05 | Basf Se | Compositions comprising mefenpyr-diethyl |
| UY39505A (es) * | 2020-11-09 | 2022-06-30 | Syngenta Crop Protection Ag | Composiciones de mezcla fungicida que comprenden un compuesto derivado de la picolinamida como ingrediente activo |
| WO2022128554A1 (en) | 2020-12-15 | 2022-06-23 | Basf Se | Mixtures containing n-methoxy-n-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]cyclopropanecarboxamide |
| TW202321234A (zh) | 2021-08-03 | 2023-06-01 | 美商科迪華農業科技有限責任公司 | 具有殺有害生物活性之多晶型物 |
| TW202345696A (zh) | 2022-05-18 | 2023-12-01 | 美商科迪華農業科技有限責任公司 | 具有殺有害生物效用之組成物及與其相關的方法 |
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| EP3004067A4 (en) * | 2013-05-28 | 2016-10-12 | Viamet Pharmaceuticals Inc | FUNGICIDE COMPOSITIONS |
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