CO2017012621A2 - Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtención - Google Patents

Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtención

Info

Publication number
CO2017012621A2
CO2017012621A2 CONC2017/0012621A CO2017012621A CO2017012621A2 CO 2017012621 A2 CO2017012621 A2 CO 2017012621A2 CO 2017012621 A CO2017012621 A CO 2017012621A CO 2017012621 A2 CO2017012621 A2 CO 2017012621A2
Authority
CO
Colombia
Prior art keywords
benzonitrile
obtaining
compounds derived
agronomic composition
agronomic
Prior art date
Application number
CONC2017/0012621A
Other languages
English (en)
Spanish (es)
Inventor
J William Hoekstra
T Michael Sullenberger
D Gary Gustafson
M Christopher Yates
J Robert Schotzinger
R Michael Loso
Kimberly Steward
Javier Delgado
Xuelin Wang
Original Assignee
Viamet Pharmaceuticals Nc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viamet Pharmaceuticals Nc Inc filed Critical Viamet Pharmaceuticals Nc Inc
Publication of CO2017012621A2 publication Critical patent/CO2017012621A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647Triazoles; Hydrogenated triazoles
    • A01N43/6531,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CONC2017/0012621A 2015-05-18 2017-12-07 Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtención CO2017012621A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562163106P 2015-05-18 2015-05-18
PCT/US2016/032877 WO2016187201A2 (en) 2015-05-18 2016-05-17 Antifungal compounds

Publications (1)

Publication Number Publication Date
CO2017012621A2 true CO2017012621A2 (es) 2018-04-30

Family

ID=57320616

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0012621A CO2017012621A2 (es) 2015-05-18 2017-12-07 Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtención

Country Status (25)

Country Link
US (2) US11051514B2 (enExample)
EP (2) EP3702353B1 (enExample)
JP (1) JP6908533B2 (enExample)
KR (1) KR20180000731A (enExample)
CN (1) CN107750248A (enExample)
AR (1) AR104695A1 (enExample)
AU (2) AU2016265932B2 (enExample)
BR (1) BR112017024463B1 (enExample)
CA (1) CA2986041C (enExample)
CL (1) CL2017002929A1 (enExample)
CO (1) CO2017012621A2 (enExample)
CR (1) CR20170574A (enExample)
DK (1) DK3297998T3 (enExample)
EA (1) EA034387B1 (enExample)
EC (1) ECSP17082683A (enExample)
ES (1) ES2776241T3 (enExample)
HK (2) HK1253073A1 (enExample)
IL (1) IL255605B (enExample)
LT (1) LT3297998T (enExample)
MX (1) MX378499B (enExample)
PH (1) PH12017502082B1 (enExample)
TW (1) TWI623527B (enExample)
UA (1) UA120784C2 (enExample)
WO (1) WO2016187201A2 (enExample)
ZA (1) ZA201707783B (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016021257B1 (pt) 2014-03-19 2021-03-02 Viamet Pharmaceuticals (NC), Inc. 2-(2,4- difluorofenil-1,1-diflúor-1-(5-substituído-piridin-2-il)-3- (1h-tetrazol-1-il)propan-2-óis e processos para preparação e uso dos mesmos
US10399943B2 (en) 2014-03-19 2019-09-03 Mycovia Pharmaceuticals, Inc. Antifungal compound process
MX365494B (es) 2014-03-19 2019-06-05 Us Health Procedimiento de compuesto antifungico.
AU2015231275B2 (en) 2014-03-19 2019-03-07 Mycovia Pharmaceuticals, Inc. Antifungal compound process
EP3119771B1 (en) 2014-03-19 2020-05-06 Mycovia Pharmaceuticals, Inc. Antifungal compound process
JP2017509646A (ja) 2014-03-19 2017-04-06 ヴィアメット ファーマスーティカルズ,インコーポレイテッド 抗真菌化合物の調製方法
JP6572234B2 (ja) 2014-03-19 2019-09-04 ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド 抗真菌化合物の調製方法
WO2015143192A1 (en) 2014-03-19 2015-09-24 Viamet Pharmaceuticals, Inc. 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and processes for their preparation
JP2017514790A (ja) 2014-03-19 2017-06-08 ヴィアメット ファーマスーティカルズ,インコーポレイテッド 抗真菌化合物の調製方法
EP3240773B9 (en) 2014-12-30 2021-01-13 Dow AgroSciences LLC Picolinamide compounds with fungicidal activity
US10513505B2 (en) 2015-09-18 2019-12-24 Nqp 1598, Ltd. Antifungal compound process
EP3377475A4 (en) * 2015-11-17 2019-04-10 Dow Agrosciences Llc 4 - ((6-2- (2,4-difluorophenyl) -1,1-difluoro-2-hydroxy-3- (1H-1,2,4-triazol-1-YL) PROPYL) PYRIDINE-3-YL ) OXY) BENZONITRIL AND METHOD OF PREPARING THEREOF
EP3376866A4 (en) * 2015-11-17 2019-04-10 Dow Agrosciences LLC 4 - ((6- (2- (2,4-DIFLUORPHENYL) -1,1-DIFLUOR-2-OXOETHYL) PYRIDIN-3-YL) BENZONITRIL AND METHOD OF PREPARING THEREOF
CA3005738C (en) * 2015-11-17 2023-10-31 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
US20180354928A1 (en) * 2015-11-17 2018-12-13 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
CN109952294A (zh) * 2016-11-18 2019-06-28 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
WO2018094147A1 (en) * 2016-11-18 2018-05-24 Vps-3, Inc. 4-((6-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
EP3541797A4 (en) * 2016-11-18 2020-04-29 Dow AgroSciences LLC 4 - ((6- (2- (2,4-DIFLUORPHENYL) -1,1-DIFLUOR-2-HYDROXY-3- (5-MERCAPTO-1H
CN110023296A (zh) * 2016-11-18 2019-07-16 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
WO2018094139A1 (en) * 2016-11-18 2018-05-24 Vps-3, Inc. 4-((6-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3(5-mercapto-1h-1,2,4-triazol-1-yl) propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation
CN109963841A (zh) * 2016-11-18 2019-07-02 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
CN110291078A (zh) * 2016-11-18 2019-09-27 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
CN109983004A (zh) * 2016-11-18 2019-07-05 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
EP3555047A4 (en) * 2016-11-18 2020-04-29 Dow AgroSciences LLC T-BUTYL-2-CARBAMOTHIOYL-2- (3- (5- (4-CYANOPHENOXY) PYRIDIN-2-YL) -2- (2,4-DIFLUORPHENYL) -3,3-DIFLUOR-2-HYDROXYPROPYL) HYDRAZIN- 1-CARBOXYLATE AND PRODUCTION METHOD
WO2018098243A1 (en) * 2016-11-22 2018-05-31 Vps-3, Inc. Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of wheat
US20190297889A1 (en) * 2016-11-22 2019-10-03 Dow Agrossciences Llc Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of rice
CA3044288A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Fungicidal compounds and mixtures for fungal control in cereals
US20210274787A1 (en) * 2016-11-22 2021-09-09 Dow Agrosciences Llc Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of leaf spot of sugar beets
BR112019010120A2 (pt) * 2016-11-22 2019-08-20 Dow Agrosciences Llc uso de um composto de difluoro-(2-hidroxipropil)piridina como um fungicida para o controle de fungos fitopatogênicos de cevada
CA3044386A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of corn
CA3044280A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Fungicidal compounds and mixtures for fungal control in cereals
AU2017363226A1 (en) * 2016-11-22 2019-06-20 Corteva Agriscience Llc Fungicidal compounds and mixtures for fungal control in cereals
AR110207A1 (es) * 2016-11-22 2019-03-06 Viamet Pharmaceuticals Inc Compuestos y mezclas fungicidas para el control de hongos en cereales
CA3044340A1 (en) * 2016-11-22 2018-05-31 Dow Agrosciences Llc Fungicidal compounds and mixtures for fungal control in cereals
TW201842851A (zh) * 2017-05-02 2018-12-16 美商陶氏農業科學公司 用於穀類中的真菌防治之協同性混合物
WO2020007647A1 (en) 2018-07-02 2020-01-09 Basf Se Pesticidal mixtures
WO2020007646A1 (en) 2018-07-02 2020-01-09 Basf Se Pesticidal mixtures
WO2020020813A1 (en) 2018-07-25 2020-01-30 Bayer Aktiengesellschaft Fungicidal active compound combinations
WO2020030454A1 (en) 2018-08-08 2020-02-13 Basf Se Use of fungicidal active compound i derivative and mixtures thereof in seed application and treatment methods
WO2020037109A1 (en) * 2018-08-17 2020-02-20 Dow Agrosciences Llc Processes for fluorination
BR112021006045A2 (pt) 2018-10-19 2021-06-29 Basf Se misturas fungicidas, composição pesticida, uso da mistura e método para o combate de parasitas fitopatogênicos
WO2020078795A1 (en) 2018-10-19 2020-04-23 Basf Se Ternary mixtures containing fenpropimorph, succinate dehydrogenase inhibitors and azoles
JP7570339B2 (ja) 2019-02-20 2024-10-21 ビーエーエスエフ ソシエタス・ヨーロピア ピラゾール化合物を含む殺有害生物剤混合物
WO2020180832A1 (en) * 2019-03-06 2020-09-10 Dow Agrosciences Llc A difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for black sigatoka
EP4044811A4 (en) 2019-10-18 2023-09-27 Corteva Agriscience LLC METHOD FOR SYNTHESIS OF PICOLINAMIDS
WO2021104910A1 (en) * 2019-11-26 2021-06-03 Basf Se Method to control septoria tritici resistant to c14-demethylase inhibitor fungicides
CN115052482A (zh) 2020-02-04 2022-09-13 科迪华农业科技有限责任公司 具有杀有害生物效用的组合物及与其相关的方法
US20230112306A1 (en) 2020-03-13 2023-04-13 Syngenta Crop Protection Ag Methods of controlling or preventing infestation of soybean plants by the phytopathogenic microorganism corynespora cassiicola
EP4117434A1 (en) 2020-03-13 2023-01-18 Syngenta Crop Protection AG Methods of controlling or preventing infestation of plants by the phytopathogenic microorganism corynespora cassiicola, cercospora sojina and/or cercospora kikuchii
BR112022018267A2 (pt) 2020-03-13 2022-10-25 Syngenta Crop Protection Ag Métodos de controle ou prevenção de infestação de plantas pelo microrganismo fitopatogênico corynespora cassiicola
BR112022019582A2 (pt) 2020-04-01 2022-11-16 Basf Se Misturas fungicidas, composição pesticida, uso da mistura e método para controlar pragas fitopatogênicas
BR112022019796A2 (pt) 2020-04-01 2022-11-16 Basf Se Misturas fungicidas, composição pesticida, uso da mistura e método para controlar pragas fitopatogênicas
WO2022073932A1 (en) 2020-10-05 2022-04-14 Syngenta Crop Protection Ag Fungicidal compositions
WO2022090069A1 (en) 2020-11-02 2022-05-05 Basf Se Compositions comprising mefenpyr-diethyl
UY39505A (es) 2020-11-09 2022-06-30 Syngenta Crop Protection Ag Composiciones de mezcla fungicida que comprenden un compuesto derivado de la picolinamida como ingrediente activo
WO2022128554A1 (en) 2020-12-15 2022-06-23 Basf Se Mixtures containing n-methoxy-n-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]cyclopropanecarboxamide
TW202321234A (zh) 2021-08-03 2023-06-01 美商科迪華農業科技有限責任公司 具有殺有害生物活性之多晶型物
TW202345696A (zh) 2022-05-18 2023-12-01 美商科迪華農業科技有限責任公司 具有殺有害生物效用之組成物及與其相關的方法
KR102518041B1 (ko) * 2022-06-16 2023-04-05 (주)유알지 마스크팩용 조성물 및 그 마스크팩용 조성물의 제조방법

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8304282D0 (en) 1983-02-16 1983-03-23 Pfizer Ltd Antifungal agents
US4690942A (en) 1983-12-20 1987-09-01 Ciba-Geigy Corporation 1-aryl-2-fluoro-2-azolyl alkanones, alkanols, esters, and ethers, composition containing them, and use of them to control phytopathogenic microorganisms
WO1989005801A1 (en) 1987-12-17 1989-06-29 E.I. Du Pont De Nemours And Company Antifungal carbinols
GB8819308D0 (en) 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
GB9121456D0 (en) 1991-10-10 1991-11-27 Pfizer Ltd Triazole antifungal agents
GB9605705D0 (en) 1996-03-19 1996-05-22 Pfizer Ltd Therapeutic agents
DE19744706A1 (de) * 1997-10-10 1999-04-15 Bayer Ag Verfahren zur Herstellung von Triazolinthion-Derivaten
WO2007003540A1 (de) 2005-06-30 2007-01-11 Basf Aktiengesellschaft Fungizide mischungen auf der basis von 2,5-disubstituierten pyrazolcarbonsäurebiphenylamiden
US8680270B2 (en) 2006-11-21 2014-03-25 Viamet Pharmaceuticals, Inc. Metallo-oxidoreductase inhibitors using metal binding moieties in combination with targeting moieties
WO2008124131A1 (en) 2007-04-05 2008-10-16 The John Hopkins University Antifungal agents as neuroprotectants
KR100889937B1 (ko) 2007-08-06 2009-03-20 한미약품 주식회사 보리코나졸의 제조방법
EP2234608A2 (en) 2007-12-11 2010-10-06 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
EP2440535A1 (en) * 2009-06-12 2012-04-18 Basf Se Antifungal 1,2,4-triazolyl derivatives having a 5- sulfur substituent
KR101109215B1 (ko) 2009-06-17 2012-01-30 보령제약 주식회사 보리코나졸의 신규 중간체 및 이를 이용한 보리코나졸의 제조방법
US20120088664A1 (en) * 2009-06-18 2012-04-12 Basf Se Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent
DK2563771T3 (en) * 2010-04-24 2016-02-29 Viamet Pharmaceuticals Inc Metalloenzyminhibitorforbindelser
WO2011134911A2 (en) 2010-04-28 2011-11-03 Bayer Cropscience Ag Fungicide hydroximoyl-tetrazole derivatives
JP5989090B2 (ja) 2011-04-15 2016-09-07 ビーエーエスエフ ソシエタス・ヨーロピアBasf Se 印刷インクにおける超分岐ポリエステル
US9388206B2 (en) 2011-05-06 2016-07-12 Basf Se Chromophores with perfluoroalkyl substituents
EP3067350B1 (en) 2011-06-19 2018-06-13 Viamet Pharmaceuticals (NC), Inc. Metalloenzyme inhibitor compounds
JP6159318B2 (ja) 2011-06-19 2017-07-05 ヴィアメット ファーマスーティカルズ,インコーポレイテッド 金属酵素阻害化合物
WO2012177728A1 (en) 2011-06-23 2012-12-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
WO2013047308A1 (ja) * 2011-09-27 2013-04-04 株式会社クレハ アゾール誘導体、農園芸用薬剤および工業用材料保護剤、植物病害防除方法ならびに種子
US9447073B2 (en) 2013-05-28 2016-09-20 Viamet Pharmaceuticals, Inc. Fungicidal compositions

Also Published As

Publication number Publication date
AU2020239669A1 (en) 2020-10-15
EP3297998A4 (en) 2018-11-14
KR20180000731A (ko) 2018-01-03
US20190216087A1 (en) 2019-07-18
AU2016265932A1 (en) 2017-12-07
WO2016187201A3 (en) 2017-03-16
EA034387B1 (ru) 2020-02-03
BR112017024463B1 (pt) 2023-01-24
CA2986041C (en) 2021-06-29
US20210360921A1 (en) 2021-11-25
ES2776241T3 (es) 2020-07-29
DK3297998T3 (da) 2020-03-16
PH12017502082A1 (en) 2018-05-07
CL2017002929A1 (es) 2018-04-27
HK1253073A1 (zh) 2019-06-06
MX378499B (es) 2025-03-11
LT3297998T (lt) 2020-06-10
JP6908533B2 (ja) 2021-07-28
TWI623527B (zh) 2018-05-11
HK1251569A1 (zh) 2019-02-01
ECSP17082683A (es) 2018-02-28
ZA201707783B (en) 2019-06-26
EP3702353B1 (en) 2023-07-05
EP3297998A2 (en) 2018-03-28
CA2986041A1 (en) 2016-11-24
JP2018522821A (ja) 2018-08-16
CN107750248A (zh) 2018-03-02
AU2016265932B2 (en) 2020-10-08
EP3702353A1 (en) 2020-09-02
BR112017024463A2 (pt) 2018-07-24
AR104695A1 (es) 2017-08-09
EP3297998B1 (en) 2019-12-11
TW201706260A (zh) 2017-02-16
EA201792519A1 (ru) 2018-04-30
US11051514B2 (en) 2021-07-06
MX2017014848A (es) 2018-04-20
CR20170574A (es) 2018-07-19
UA120784C2 (uk) 2020-02-10
PH12017502082B1 (en) 2024-05-15
WO2016187201A2 (en) 2016-11-24
IL255605B (en) 2021-03-25
IL255605A (en) 2018-01-31

Similar Documents

Publication Publication Date Title
CO2017012621A2 (es) Compuestos derivados de benzonitrilo, composición agronómica que los comprende y proceso para su obtención
MX380092B (es) Tratamiento de la osteoartritis.
NI201600165A (es) Inhibidores de desmetilasa 1 específica a lisina
TW201613872A (en) IRAK4 inhibiting agents
EA201792205A1 (ru) Гетероциклические соединения как ингибиторы lsd1
CL2017000521A1 (es) Inhibidores de desmetilasa-1 específica a lisina
MX373247B (es) Nuevos derivados de octahidro-pirrolo[3,4-c]-pirrol y análogos del mismo como inhibidores de atotaxina.
UY36122A (es) ?derivados de pirrolidina-2,5-diona, composiciones farmacéuticas y métodos para usar como inhibidores ido1?
UY35683A (es) Polimorfo de inhibidores de tirosina quinasa de bazo (syk)
MX2018003130A (es) Compuestos de heteroarilo como inhibidores de cinasas asociadas a receptor de interleucina-1 (irak) y usos de los mismos.
CL2017001650A1 (es) Derivados de 5-[(piperazina-1-yl)-3-oxo-propilo]-imidazolidina-2,4-dionan como inhibidores adamts para el tratamiento oesteoartritis.
CO2017003838A2 (es) Compuestos de aminopurina sustituida, composiciones del mismo, y métodos de tratamiento con los mismos
MX2020001278A (es) Sintesis de compuestos de carbamoilpiridona policiclica.
SV2017005381A (es) Compuestos de imidazopiridazina
PH12016501462A1 (en) Neprilysin inhibitors
MX2016009352A (es) Inhibidores de quinasa a base de quinolina.
BR112017000730A2 (pt) derivados de pirrolidinona como inibidores de metap-2
MX387796B (es) Compuestos de aminocarbonilcarbamato.
EP3500257A4 (en) KINASE INHIBITOR COMPOSITIONS AND METHODS FOR TREATING CANCER
SG10201900564WA (en) Methods for treating cancer
MA40250A (fr) Dérivés de quinolizinone utilisés comme inhibiteurs de pi3k
CL2017000484A1 (es) Compuestos de azetidiniloxifenilpirrolidina
DOP2019000021A (es) Derivado de triazolopirazinona útil como un inhibidor de pde1 humana
MX2014013758A (es) Derivados de tiazolcarboxamida para usarse como inhibidores de nampt.
MX388409B (es) Composiciones y metodos para tratar canceres.