IL207378A0 - Pharmaceutical solid state forms - Google Patents
Pharmaceutical solid state formsInfo
- Publication number
- IL207378A0 IL207378A0 IL207378A IL20737810A IL207378A0 IL 207378 A0 IL207378 A0 IL 207378A0 IL 207378 A IL207378 A IL 207378A IL 20737810 A IL20737810 A IL 20737810A IL 207378 A0 IL207378 A0 IL 207378A0
- Authority
- IL
- Israel
- Prior art keywords
- solid state
- state forms
- pharmaceutical solid
- pharmaceutical
- forms
- Prior art date
Links
- 239000007787 solid Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2647208P | 2008-02-05 | 2008-02-05 | |
| US9369408P | 2008-09-02 | 2008-09-02 | |
| PCT/US2009/033280 WO2009100258A1 (en) | 2008-02-05 | 2009-02-05 | Pharmaceutical solid state forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL207378A0 true IL207378A0 (en) | 2010-12-30 |
Family
ID=40952461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL207378A IL207378A0 (en) | 2008-02-05 | 2010-08-03 | Pharmaceutical solid state forms |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US8518922B2 (enExample) |
| EP (1) | EP2249838A4 (enExample) |
| JP (1) | JP2011511011A (enExample) |
| KR (1) | KR20100113602A (enExample) |
| CN (2) | CN101939009B (enExample) |
| AU (1) | AU2009212314C1 (enExample) |
| CA (1) | CA2712005C (enExample) |
| EA (1) | EA018974B9 (enExample) |
| IL (1) | IL207378A0 (enExample) |
| WO (1) | WO2009100258A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2225230T (pt) | 2007-12-07 | 2016-12-07 | Vertex Pharma | Formas sólidas de ácido 3-(6(1-(2,2-difluorobenzo[d][1,3] dioxol-5-il) ciclopropanocarboxamido)-3-metilpiridin-2-il) benzoico |
| HUE028337T2 (en) * | 2008-04-03 | 2016-12-28 | Neurmedix Inc | Shapes of a drug in a solid state |
| WO2011066582A1 (en) * | 2009-11-30 | 2011-06-03 | Harbor Biosciences, Inc. | Anticancer compounds and screening method |
| AU2011205230A1 (en) | 2010-01-13 | 2012-08-02 | Caris Life Sciences Switzerland Holdings Gmbh | Detection of gastrointestinal disorders |
| KR20130056855A (ko) | 2010-03-01 | 2013-05-30 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 치료진단용 생물학적 지표들 |
| KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| US20120220560A1 (en) * | 2010-12-17 | 2012-08-30 | White Steven K | Steroid tetrol solid state forms |
| CN104173353B (zh) * | 2013-05-22 | 2018-08-21 | 中国医药工业研究总院 | 不含表面活性剂的固体制剂及其制备方法 |
| KR102280372B1 (ko) * | 2013-11-12 | 2021-07-22 | 버텍스 파마슈티칼스 인코포레이티드 | Cftr 매개된 질환 치료용 약제학적 조성물의 제조 방법 |
| CN105434444B (zh) * | 2014-09-29 | 2021-02-05 | 上海奥奇医药科技有限公司 | 一种A-失碳-5α雄甾烷化合物的口服制剂 |
| CN113559075A (zh) | 2014-11-17 | 2021-10-29 | 康泰科思特生物制药公司 | 奥那司酮延长释放组合物和方法 |
| US10308676B2 (en) | 2015-09-25 | 2019-06-04 | Context Biopharma Inc. | Methods of making onapristone intermediates |
| JP2019503353A (ja) | 2015-12-15 | 2019-02-07 | コンテキスト・バイオファーマ・インコーポレイテッド | 非晶質オナプリストン組成物およびそれを作製する方法 |
| US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
| CN110446705B (zh) * | 2017-03-30 | 2023-04-14 | 默克专利股份公司 | (s)-[2-氯-4-氟-5-(7-吗啉-4-基喹唑啉-4-基)苯基]-(6-甲氧基-哒嗪-3-基)甲醇的固体形式 |
| RU2668526C1 (ru) * | 2017-08-18 | 2018-10-01 | Федеральное государственное бюджетное учреждение "Информационно-методический центр по экспертизе, учету и анализу обращения средств медицинского применения" Федеральной службы по надзору в сфере здравоохранения | Способ идентификации и последующего количественного определения основных компонентов в инъекционных лекарственных средствах |
| WO2020113237A1 (en) | 2018-11-30 | 2020-06-04 | Caris Mpi, Inc. | Next-generation molecular profiling |
| CN111773388B (zh) * | 2019-04-04 | 2023-07-18 | 上海奥奇医药科技有限公司 | A-失碳-5α雄甾烷化合物类药物与抗癌药物的联合应用 |
| IL293489A (en) | 2019-12-02 | 2022-08-01 | Caris Mpi Inc | predictor of pan-cancer platinum response |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE681869C (de) * | 1935-11-22 | 1939-10-03 | Schering Ag | Verfahren zur Darstellung von tertiaeren Alkoholen der Cyclopentanopolyhydrophenanthrenreihe |
| CH202847A (de) * | 1937-06-26 | 1939-02-15 | Chem Ind Basel | Verfahren zur Darstellung von Acetylen-Derivaten der Cyclopentanopolyhydrophenanthren-Reihe. |
| DK0614456T3 (da) * | 1992-08-28 | 1999-12-06 | Bone Care Int Inc | 1alfa,24(S)-dihydroxy-vitamin D2, dets fremstilling og anvendelse |
| US5567830A (en) * | 1994-02-14 | 1996-10-22 | Cocensys, Inc. | Process for synthesis of acetylenic carbinols |
| PL189256B1 (pl) | 1996-03-29 | 2005-07-29 | Duphar Int Res | Związki piperazyny i piperydyny, sposób ich wytwarzania, kompozycja farmaceutyczna zawierająca te związki, zastosowanie tych związków do wytwarzania leków |
| ZA986614B (en) * | 1997-07-25 | 1999-01-27 | Gilead Sciences | Nucleotide analog composition |
| US7045513B1 (en) * | 1999-03-18 | 2006-05-16 | Genelabs Technologies, Inc. | DHEA composition and method |
| WO2001023405A2 (en) | 1999-09-30 | 2001-04-05 | Hollis-Eden Pharmaceuticals, Inc. | Therapeutic treatment of androgen receptor driven conditions |
| US6777399B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| MXPA03005339A (es) * | 2000-12-14 | 2004-03-26 | Johnson & Johnson | Productos de hormona esteroide que comprenden un agente de estabilizacion en forma no cristalina. |
| AR034206A1 (es) | 2001-02-16 | 2004-02-04 | Solvay Pharm Bv | Un procedimiento para la preparacion de mesilatos de derivados de piperazina y dichos mesilatos |
| DE10314610A1 (de) * | 2003-04-01 | 2004-11-04 | Aventis Pharma Deutschland Gmbh | Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung |
| US7540016B2 (en) * | 2004-07-21 | 2009-05-26 | Beachhead Solutions, Inc. | System and method for lost data destruction of electronic data stored on a portable electronic device which communicates with servers that are inside of and outside of a firewall |
| US7964604B2 (en) * | 2005-02-18 | 2011-06-21 | Solvay Pharmaceuticals B.V. | Bifeprunox mesylate maintenance dose compositions and methods for using the same |
| TW200730505A (en) * | 2005-12-07 | 2007-08-16 | Merck & Co Inc | Polymorphs of an androgen receptor modulator |
| TWI305979B (en) * | 2006-03-24 | 2009-02-01 | Hon Hai Prec Ind Co Ltd | Wireless transceiving system |
| CN103211821A (zh) * | 2006-04-22 | 2013-07-24 | 霍利斯—伊登医药公司 | 药物和用途 |
| DE102007063671A1 (de) * | 2007-11-13 | 2009-06-25 | Sanofi-Aventis Deutschland Gmbh | Neue kristalline Diphenylazetidinonhydrate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
-
2009
- 2009-02-05 JP JP2010545285A patent/JP2011511011A/ja active Pending
- 2009-02-05 EA EA201070713A patent/EA018974B9/ru not_active IP Right Cessation
- 2009-02-05 CA CA2712005A patent/CA2712005C/en not_active Expired - Fee Related
- 2009-02-05 KR KR1020107019161A patent/KR20100113602A/ko not_active Ceased
- 2009-02-05 WO PCT/US2009/033280 patent/WO2009100258A1/en not_active Ceased
- 2009-02-05 CN CN200980104255XA patent/CN101939009B/zh not_active Expired - Fee Related
- 2009-02-05 CN CN2013102558234A patent/CN103467554A/zh active Pending
- 2009-02-05 AU AU2009212314A patent/AU2009212314C1/en not_active Ceased
- 2009-02-05 EP EP09709386A patent/EP2249838A4/en not_active Withdrawn
- 2009-02-12 US US12/370,510 patent/US8518922B2/en active Active
-
2010
- 2010-08-03 IL IL207378A patent/IL207378A0/en unknown
-
2013
- 2013-06-17 US US13/919,386 patent/US20130345184A1/en not_active Abandoned
- 2013-06-17 US US13/919,728 patent/US20130338125A1/en not_active Abandoned
- 2013-06-17 US US13/919,593 patent/US9314471B2/en active Active - Reinstated
Also Published As
| Publication number | Publication date |
|---|---|
| KR20100113602A (ko) | 2010-10-21 |
| HK1147695A1 (en) | 2011-08-19 |
| WO2009100258A1 (en) | 2009-08-13 |
| EA018974B9 (ru) | 2014-04-30 |
| CA2712005C (en) | 2014-04-15 |
| EA018974B1 (ru) | 2013-12-30 |
| US9314471B2 (en) | 2016-04-19 |
| CN101939009B (zh) | 2013-07-17 |
| US8518922B2 (en) | 2013-08-27 |
| JP2011511011A (ja) | 2011-04-07 |
| CA2712005A1 (en) | 2009-08-13 |
| EP2249838A1 (en) | 2010-11-17 |
| AU2009212314C1 (en) | 2014-05-08 |
| US20130345455A1 (en) | 2013-12-26 |
| US20130345184A1 (en) | 2013-12-26 |
| AU2009212314A1 (en) | 2009-08-13 |
| CN103467554A (zh) | 2013-12-25 |
| AU2009212314B2 (en) | 2013-11-21 |
| EP2249838A4 (en) | 2012-05-02 |
| US20090291932A1 (en) | 2009-11-26 |
| US20130338125A1 (en) | 2013-12-19 |
| EA201070713A1 (ru) | 2011-08-30 |
| CN101939009A (zh) | 2011-01-05 |
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