IL202459A - Method for simultaneous detection and diagnosis of bacterial, fungal, parasitic and viral infections of the eye and central nervous system - Google Patents
Method for simultaneous detection and diagnosis of bacterial, fungal, parasitic and viral infections of the eye and central nervous systemInfo
- Publication number
- IL202459A IL202459A IL202459A IL20245909A IL202459A IL 202459 A IL202459 A IL 202459A IL 202459 A IL202459 A IL 202459A IL 20245909 A IL20245909 A IL 20245909A IL 202459 A IL202459 A IL 202459A
- Authority
- IL
- Israel
- Prior art keywords
- fungal
- discrimination
- parasitic
- bacterial
- eye
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 206010017533 Fungal infection Diseases 0.000 title 1
- 208000031888 Mycoses Diseases 0.000 title 1
- 208000030852 Parasitic disease Diseases 0.000 title 1
- 208000036142 Viral infection Diseases 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 230000002538 fungal effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000003071 parasitic effect Effects 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/101—Temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2561/00—Nucleic acid detection characterised by assay method
- C12Q2561/113—Real time assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1178DE2007 | 2007-06-01 | ||
| PCT/IN2008/000334 WO2008146306A2 (en) | 2007-06-01 | 2008-05-27 | A novel method for simultaneous detection and discrimination of bacterial, fungal, parasitic and viral infections of eye and central nervous system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL202459A0 IL202459A0 (en) | 2011-08-01 |
| IL202459A true IL202459A (en) | 2014-09-30 |
Family
ID=39831681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL202459A IL202459A (en) | 2007-06-01 | 2009-12-01 | Method for simultaneous detection and diagnosis of bacterial, fungal, parasitic and viral infections of the eye and central nervous system |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8465951B2 (OSRAM) |
| EP (1) | EP2155909B1 (OSRAM) |
| JP (2) | JP5718049B2 (OSRAM) |
| KR (1) | KR101866766B1 (OSRAM) |
| CN (2) | CN101541979B (OSRAM) |
| AR (2) | AR066825A1 (OSRAM) |
| AU (1) | AU2008256216B2 (OSRAM) |
| BR (1) | BRPI0812178A2 (OSRAM) |
| CA (1) | CA2689306C (OSRAM) |
| IL (1) | IL202459A (OSRAM) |
| MY (2) | MY150954A (OSRAM) |
| NZ (1) | NZ582232A (OSRAM) |
| TW (1) | TWI410491B (OSRAM) |
| WO (1) | WO2008146306A2 (OSRAM) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2661474B1 (fr) | 1990-04-25 | 1992-06-12 | Valeo | Double volant amortisseur de torsion pour moteur a combustion interne. |
| JP2788853B2 (ja) | 1994-02-14 | 1998-08-20 | 株式会社エクセディ | ダンパー装置 |
| JP5718049B2 (ja) * | 2007-06-01 | 2015-05-13 | カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチCouncil Of Scientific & Industrial Research | 眼および中枢神経系の細菌、真菌、寄生虫およびウイルス感染の同時検出と識別のための新規な方法 |
| WO2010130877A2 (en) * | 2009-05-12 | 2010-11-18 | Abacus Diagnostica Oy | Method for detecting nucleic acids |
| EP2270202A1 (en) * | 2009-07-03 | 2011-01-05 | John Ikonomopoulos | Mycobacterial detection |
| US9726668B2 (en) | 2012-02-09 | 2017-08-08 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections and methods of use thereof |
| US20130302784A1 (en) * | 2012-03-30 | 2013-11-14 | Intelligent Medical Devices, Inc. | Optimized probes and primers and methods of using same for the binding, detection, differentiation, isolation and sequencing of herpes simplex virus |
| CN103045761B (zh) * | 2012-12-14 | 2016-01-20 | 山东省眼科研究所 | 用于检测感染性眼病致病微生物的试剂盒及检测方法 |
| WO2014186874A1 (en) | 2013-05-23 | 2014-11-27 | Yyz Pharmatech, Inc. | Methods and compositions for enzyme linked immuno and hybridization mass spectrometric assay |
| CA3190715A1 (en) | 2014-08-14 | 2016-02-18 | Memed Diagnostics Ltd. | Computational analysis of biological data using manifold and a hyperplane |
| CN204050005U (zh) * | 2014-09-09 | 2014-12-31 | 赵潺 | 一次性负压前房穿刺针 |
| WO2016059636A1 (en) | 2014-10-14 | 2016-04-21 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof |
| EP3215616B1 (en) * | 2014-11-05 | 2019-12-18 | Illumina Cambridge Limited | Reducing dna damage during sample preparation and sequencing using siderophore chelators |
| JP6723924B2 (ja) * | 2014-11-19 | 2020-07-15 | 大塚製薬株式会社 | Pkd1遺伝子及びpkd2遺伝子のエクソンを増幅するためのプライマーセット及び方法 |
| CN107209184B (zh) | 2014-12-11 | 2020-04-24 | 米密德诊断学有限公司 | 用于诊断多种感染的标记组合及其使用方法 |
| KR101521409B1 (ko) * | 2015-01-15 | 2015-05-18 | 경북대학교 산학협력단 | 진균성 및 아메바성 각막염의 원인체를 동시에 검출할 수 있는 다중 중합효소 연쇄반응 프라이머 세트 및 이를 이용한 각막염 유발균 검출 방법 |
| EP3154439A1 (en) * | 2015-05-19 | 2017-04-19 | Yaya Diagnostics GmbH | Means and methods for the enrichment of nucleic acids |
| WO2017149548A1 (en) | 2016-03-03 | 2017-09-08 | Memed Diagnostics Ltd. | Rna determinants for distinguishing between bacterial and viral infections |
| CN108699609A (zh) | 2016-03-03 | 2018-10-23 | 米密德诊断学有限公司 | 分析rna用于诊断感染类型 |
| CN106167833B (zh) * | 2016-05-20 | 2019-09-20 | 南方医科大学 | 一种同时检测8种虫媒脑炎病毒的rt-pcr引物和探针组合及试剂盒 |
| EP3482201B1 (en) | 2016-07-10 | 2022-12-14 | Memed Diagnostics Ltd. | Early diagnosis of infections |
| EP4141448A1 (en) | 2016-07-10 | 2023-03-01 | MeMed Diagnostics Ltd. | Protein signatures for distinguishing between bacterial and viral infections |
| WO2018060998A1 (en) | 2016-09-29 | 2018-04-05 | Memed Diagnostics Ltd. | Methods of prognosis and treatment |
| EP3519834A4 (en) | 2016-09-29 | 2020-06-17 | MeMed Diagnostics Ltd. | RISK ASSESSMENT AND DISEASE CLASSIFICATION METHODS |
| CN106834548B (zh) * | 2017-03-30 | 2020-03-27 | 广州基迪奥生物科技有限公司 | 一种常见眼内感染病毒多重实时荧光pcr检测试剂盒 |
| US10209260B2 (en) | 2017-07-05 | 2019-02-19 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections and methods of use thereof |
| WO2019126523A2 (en) * | 2017-12-22 | 2019-06-27 | Massachusetts Eye And Ear Infirmary | Comprehensive microbial panel for molecular diagnosis of eye infections |
| KR102297545B1 (ko) * | 2020-02-06 | 2021-09-02 | 경희대학교 산학협력단 | 코리스메이트 뮤테이즈 단백질 항체를 포함하는 가시아메바성 각막염의 감별 진단용 조성물 및 이를 이용한 가시아메바성 각막염 진단 키트 |
| CN111763767A (zh) * | 2020-06-04 | 2020-10-13 | 上海捷诺生物科技有限公司 | 中枢神经系统感染病原体检测试剂盒及其应用 |
| CN113201599B (zh) * | 2021-06-03 | 2023-03-31 | 北京大学人民医院 | 一种基于PCR和nanopore测序检测脑脊液感染哪些病原体的方法 |
| CN114277167A (zh) * | 2021-12-31 | 2022-04-05 | 杭州千基生物科技有限公司 | 一种用于细菌性肠道病原体的量子点核酸检测的试剂盒 |
| CN114891870A (zh) * | 2022-06-26 | 2022-08-12 | 杭州奥明医学检验实验室有限公司 | 一种基于mNGS检测致癌病原体的方法、系统及装置 |
| CN116144811B (zh) * | 2022-12-21 | 2024-02-20 | 迪飞医学科技(南京)有限公司 | 用于检测脑脊液病原的多重引物组、方法和试剂盒 |
| CN116121428A (zh) * | 2023-03-17 | 2023-05-16 | 郑州安图生物工程股份有限公司 | 引物探针组合及试剂盒 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639871A (en) | 1988-09-09 | 1997-06-17 | Roche Molecular Systems, Inc. | Detection of human papillomavirus by the polymerase chain reaction |
| JPH10323189A (ja) * | 1997-05-23 | 1998-12-08 | Toyobo Co Ltd | 抗酸菌属細菌の検出または菌種同定用オリゴヌクレオチドおよびその用途 |
| US6514694B2 (en) * | 1997-12-19 | 2003-02-04 | Heska Corporation | Methods for the detection of encysted parasites |
| AU4620100A (en) | 1999-05-29 | 2000-12-18 | Cheol Min Kim | Oligonucleotide for detection and identification of mycobacteria |
| US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
| US20040121311A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents in livestock |
| JP2003144153A (ja) | 2001-11-09 | 2003-05-20 | Gifu Univ | 遺伝子検出方法、遺伝子検出用プライマー、dnaマイクロアレイ及び遺伝子検出用キット |
| CN1329523C (zh) * | 2002-08-09 | 2007-08-01 | 中国人民解放军基因工程研究所 | 一种限制性荧光标记方法 |
| CN1508264A (zh) * | 2002-12-18 | 2004-06-30 | 云南大学 | 一种临床感染性疾病基因芯片诊断方案 |
| DE602004032125D1 (de) * | 2003-05-07 | 2011-05-19 | Coris Bioconcept Sprl | Einstufige oligochromatographische vorrichtung und verfahren zu ihrer verwendung |
| CN1195070C (zh) * | 2003-05-09 | 2005-03-30 | 陶开华 | 一种检测多种传染病的检测型基因芯片及应用 |
| CN105087777A (zh) * | 2004-04-07 | 2015-11-25 | 安克塞斯生物公司 | 核酸检测系统 |
| JP2006129810A (ja) * | 2004-11-08 | 2006-05-25 | Canon Inc | 感染症起炎菌検出用プローブセット及び担体及び遺伝子検査方法 |
| CA2596059C (en) | 2005-01-31 | 2015-08-04 | Kabushiki Kaisha Yakult Honsha | Method of quantitatively analysing microorganism targeting rrna |
| CN101351559A (zh) * | 2005-11-09 | 2009-01-21 | 普里梅拉生物系统有限公司 | 病原体的多元定量检测 |
| CN1896284B (zh) * | 2006-06-30 | 2013-09-11 | 博奥生物有限公司 | 一种鉴别等位基因类型的方法 |
| CN1995387B (zh) * | 2006-11-07 | 2010-06-23 | 亚能生物技术(深圳)有限公司 | 分枝杆菌菌种鉴定基因芯片检测系统 |
| JP5718049B2 (ja) * | 2007-06-01 | 2015-05-13 | カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチCouncil Of Scientific & Industrial Research | 眼および中枢神経系の細菌、真菌、寄生虫およびウイルス感染の同時検出と識別のための新規な方法 |
-
2008
- 2008-05-27 JP JP2010509951A patent/JP5718049B2/ja not_active Expired - Fee Related
- 2008-05-27 KR KR1020097027361A patent/KR101866766B1/ko not_active Expired - Fee Related
- 2008-05-27 BR BRPI0812178-8A patent/BRPI0812178A2/pt not_active Application Discontinuation
- 2008-05-27 EP EP08763747.6A patent/EP2155909B1/en not_active Not-in-force
- 2008-05-27 NZ NZ582232A patent/NZ582232A/en not_active IP Right Cessation
- 2008-05-27 AU AU2008256216A patent/AU2008256216B2/en not_active Ceased
- 2008-05-27 US US12/602,564 patent/US8465951B2/en not_active Expired - Fee Related
- 2008-05-27 CA CA2689306A patent/CA2689306C/en not_active Expired - Fee Related
- 2008-05-27 CN CN200880000035.8A patent/CN101541979B/zh not_active Expired - Fee Related
- 2008-05-27 CN CN201410521073.5A patent/CN104313180B/zh not_active Expired - Fee Related
- 2008-05-27 MY MYPI20095120 patent/MY150954A/en unknown
- 2008-05-27 MY MYPI2013004723A patent/MY163053A/en unknown
- 2008-05-27 WO PCT/IN2008/000334 patent/WO2008146306A2/en not_active Ceased
- 2008-05-29 TW TW097119896A patent/TWI410491B/zh not_active IP Right Cessation
- 2008-06-02 AR ARP080102330A patent/AR066825A1/es active IP Right Grant
-
2009
- 2009-12-01 IL IL202459A patent/IL202459A/en not_active IP Right Cessation
-
2013
- 2013-03-18 US US13/845,925 patent/US9777339B2/en not_active Expired - Fee Related
-
2014
- 2014-07-04 JP JP2014138799A patent/JP5927243B2/ja not_active Expired - Fee Related
-
2017
- 2017-03-23 US US15/467,748 patent/US10584392B2/en not_active Expired - Fee Related
-
2018
- 2018-01-25 AR ARP180100170A patent/AR110776A2/es not_active Application Discontinuation
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| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees | ||
| KB | Patent renewed | ||
| KB | Patent renewed |