IL201505A0 - Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals - Google Patents
Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticalsInfo
- Publication number
- IL201505A0 IL201505A0 IL201505A IL20150509A IL201505A0 IL 201505 A0 IL201505 A0 IL 201505A0 IL 201505 A IL201505 A IL 201505A IL 20150509 A IL20150509 A IL 20150509A IL 201505 A0 IL201505 A0 IL 201505A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceuticals
- production
- receptor ligands
- vanilloid receptor
- novel vanilloid
- Prior art date
Links
- 102000011040 TRPV Cation Channels Human genes 0.000 title 1
- 108010062740 TRPV Cation Channels Proteins 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Addiction (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
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Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007018149A DE102007018149A1 (de) | 2007-04-16 | 2007-04-16 | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
EP2008002997 | 2008-04-15 | ||
US12/103,667 US8084484B2 (en) | 2007-04-16 | 2008-04-15 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions |
PCT/EP2008/003027 WO2008125342A2 (de) | 2007-04-16 | 2008-04-16 | Vanilloid-rezeptor-liganden und ihre verwendung zur herstellung von arzneimitteln |
Publications (1)
Publication Number | Publication Date |
---|---|
IL201505A0 true IL201505A0 (en) | 2010-05-31 |
Family
ID=41360190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL201505A IL201505A0 (en) | 2007-04-16 | 2009-10-14 | Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals |
Country Status (14)
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007018149A1 (de) | 2007-04-16 | 2008-10-23 | Grünenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
US8946204B2 (en) | 2009-05-07 | 2015-02-03 | Gruenenthal Gmbh | Substituted phenylureas and phenylamides as vanilloid receptor ligands |
MX2011011797A (es) | 2009-05-07 | 2011-11-29 | Gruenenthal Gmbh | Fenilureas y fenilamidas sustituidas como ligandos del receptor de vanilloides. |
AR087302A1 (es) | 2011-07-26 | 2014-03-12 | Gruenenthal Gmbh | Derivados aza heterociclicos sustituidos |
KR20140049028A (ko) | 2011-07-26 | 2014-04-24 | 그뤼넨탈 게엠베하 | 바닐로이드 수용체 리간드로서의 치환된 바이사이클릭 방향족 카복스아미드 및 우레아 유도체 |
HK1202116A1 (en) * | 2011-11-09 | 2015-09-18 | Grünenthal GmbH | Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an n-containing group as vanilloid receptor ligands |
DK2822928T3 (en) * | 2012-03-05 | 2019-03-11 | Dr Reddys Laboratories Ltd | SUBSTITUTED HETEROCYCLIC ACETAMIDS AS CAPE-OPIOID RECEPTOR (CHOR) AGONISTS |
US10351535B2 (en) | 2013-12-20 | 2019-07-16 | Esteve Pharmaceuticals, S.A. | Piperazine derivatives having multimodal activity against pain |
CN107721919B (zh) * | 2017-10-30 | 2020-12-08 | 中国药科大学 | 苯基喹啉类trpv1拮抗剂及其制备方法和应用 |
KR102334947B1 (ko) * | 2020-04-22 | 2021-12-06 | 주식회사 제이맥켐 | Trpv1 길항제로서 벤즈이미다졸론계 시남아마이드 유도체 및 이를 유효성분으로 함유하는 통증의 치료 또는 예방용 약학적 조성물 |
RU2755206C1 (ru) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Средство пролонгированного анальгетического действия и лекарственный препарат на его основе |
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US20050009815A1 (en) * | 2001-11-27 | 2005-01-13 | Devita Robert J. | 4-Aminoquinoline compounds |
WO2003070247A1 (en) * | 2002-02-20 | 2003-08-28 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor |
GB0206876D0 (en) * | 2002-03-22 | 2002-05-01 | Merck Sharp & Dohme | Therapeutic agents |
US6933311B2 (en) * | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
US20060211774A1 (en) * | 2003-04-29 | 2006-09-21 | Bennett Simon T | Method of diagnosins a genetic susceptibility for bone damage |
SE0301446D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
AU2004247559B2 (en) * | 2003-06-12 | 2009-08-27 | Astellas Pharma Inc. | Benzamide derivative or salt thereof |
US20050113576A1 (en) * | 2003-08-05 | 2005-05-26 | Chih-Hung Lee | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
GB0322016D0 (en) * | 2003-09-19 | 2003-10-22 | Merck Sharp & Dohme | New compounds |
EP1685112B1 (en) * | 2003-11-08 | 2011-07-20 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydro-quinolinylurea derivatives as vr1 antagonists |
US20050165015A1 (en) * | 2004-01-23 | 2005-07-28 | Ncube Mghele V. | Vanilloid receptor ligands and their use in treatments |
DE102005023943A1 (de) * | 2005-05-20 | 2006-11-23 | Grünenthal GmbH | Pentafluorsulfanyl-substituierte Verbindung und deren Verwendung zur Herstellung von Arzneimitteln |
CA2856037C (en) * | 2005-12-28 | 2017-03-07 | Vertex Pharmaceuticals Incorporated | Modulators of atp-binding cassette transporters |
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- 2008-04-16 JP JP2010503397A patent/JP2010523727A/ja not_active Ceased
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- 2008-04-16 KR KR1020097023887A patent/KR20100016593A/ko not_active Ceased
- 2008-04-16 RU RU2009142023/04A patent/RU2498982C2/ru not_active IP Right Cessation
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- 2008-04-16 WO PCT/EP2008/003027 patent/WO2008125342A2/de active Application Filing
- 2008-04-16 CA CA002683461A patent/CA2683461A1/en not_active Abandoned
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ECSP099692A (es) | 2009-11-30 |
CO6241154A2 (es) | 2011-01-20 |
CN101679370A (zh) | 2010-03-24 |
AU2008238250A1 (en) | 2008-10-23 |
WO2008125342A3 (de) | 2009-01-15 |
MX2009011149A (es) | 2009-10-30 |
CA2683461A1 (en) | 2008-10-23 |
AU2008238250B2 (en) | 2013-01-24 |
WO2008125342A2 (de) | 2008-10-23 |
RU2009142023A (ru) | 2011-05-27 |
ZA200907099B (en) | 2013-03-27 |
JP2010523727A (ja) | 2010-07-15 |
KR20100016593A (ko) | 2010-02-12 |
BRPI0810035A2 (pt) | 2016-07-26 |
RU2498982C2 (ru) | 2013-11-20 |
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