IL174600A - Crystalline form of gamma-aminobutyric acid analogue - Google Patents
Crystalline form of gamma-aminobutyric acid analogueInfo
- Publication number
- IL174600A IL174600A IL174600A IL17460006A IL174600A IL 174600 A IL174600 A IL 174600A IL 174600 A IL174600 A IL 174600A IL 17460006 A IL17460006 A IL 17460006A IL 174600 A IL174600 A IL 174600A
- Authority
- IL
- Israel
- Prior art keywords
- acetic acid
- carbonyl
- cyclohexane acetic
- isobutanoyloxyethoxy
- aminomethyl
- Prior art date
Links
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical class NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 title abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 33
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims description 133
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 claims description 106
- 239000000203 mixture Substances 0.000 claims description 37
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 claims description 26
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- 239000000843 powder Substances 0.000 claims description 23
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 21
- 229910002483 Cu Ka Inorganic materials 0.000 claims description 13
- UAEPNZWRGJTJPN-UHFFFAOYSA-N methylcyclohexane Chemical compound CC1CCCCC1 UAEPNZWRGJTJPN-UHFFFAOYSA-N 0.000 claims description 13
- 230000005855 radiation Effects 0.000 claims description 13
- -1 α-isobutanoyloxyethoxy Chemical group 0.000 claims description 12
- 238000002844 melting Methods 0.000 claims description 9
- 230000008018 melting Effects 0.000 claims description 9
- BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 claims description 7
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| US9932294B2 (en) | 2014-12-01 | 2018-04-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
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| CN110845355A (zh) | 2015-01-06 | 2020-02-28 | 塞尔利克斯生物私人有限公司 | 用于治疗炎症和疼痛的组合物和方法 |
| RU2739192C1 (ru) * | 2020-06-18 | 2020-12-21 | федеральное государственное бюджетное образовательное учреждение высшего образования «Омский государственный медицинский университет» Министерства здравоохранения Российской Федерации (ФГБОУ ВО ОмГМУ Минздрава России) | Способ лечения абстинентного синдрома, с целью превенции развития психоза, у лиц с зависимостью от синтетических агонистов рецепторов гамма-аминомасляной кислоты: бутиролактона, 1,4-бутандиола |
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- 2008-12-22 JP JP2008325914A patent/JP4913796B2/ja not_active Expired - Lifetime
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- 2009-08-26 US US12/548,200 patent/US20100056632A1/en not_active Abandoned
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