SE9603408D0 - Medical use - Google Patents
Medical useInfo
- Publication number
- SE9603408D0 SE9603408D0 SE9603408A SE9603408A SE9603408D0 SE 9603408 D0 SE9603408 D0 SE 9603408D0 SE 9603408 A SE9603408 A SE 9603408A SE 9603408 A SE9603408 A SE 9603408A SE 9603408 D0 SE9603408 D0 SE 9603408D0
- Authority
- SE
- Sweden
- Prior art keywords
- medical use
- gastro
- inhibition
- treatment
- receptor agonists
- Prior art date
Links
- 208000021302 gastroesophageal reflux disease Diseases 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 210000000111 lower esophageal sphincter Anatomy 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 230000001052 transient effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
- G01N33/9426—GABA, i.e. gamma-amino-butyrate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (47)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9603408A SE9603408D0 (sv) | 1996-09-18 | 1996-09-18 | Medical use |
ARP970104051A AR007747A1 (es) | 1996-09-18 | 1997-09-04 | Inhibidores del reflujo |
ZA9707969A ZA977969B (en) | 1996-09-18 | 1997-09-04 | Reflux inhibitors. |
TW086113275A TW548104B (en) | 1996-09-18 | 1997-09-12 | Pharmaceutical compositions for inhibiting transient lower esophageal sphincter relaxations |
IDP973172A ID19621A (id) | 1996-09-18 | 1997-09-12 | Penghambat refluks |
EEP199900095A EE03952B1 (et) | 1996-09-18 | 1997-09-15 | Tagasivoolu inhibiitorid |
UA99031298A UA61081C2 (uk) | 1996-09-18 | 1997-09-15 | Активний компонент для придушення тимчасових релаксацій нижнього сфінктера, спосіб такого придушення та спосіб скринінгу сполук |
RU99107969/14A RU2199316C2 (ru) | 1996-09-18 | 1997-09-15 | Вещества, подавляющие рефлюкс |
HU9903825A HU224968B1 (en) | 1996-09-18 | 1997-09-15 | Use of gabab receptor agonists for production of anti reflux pharmaceutical compositions |
DE69724809T DE69724809T2 (de) | 1996-09-18 | 1997-09-15 | Refluxinhibitoren |
NZ334495A NZ334495A (en) | 1996-09-18 | 1997-09-15 | Use of GABA receptor agonists such as substituted amino propyl acid derivatives to inhibit transient lower esophageal sphincter relaxations |
SI9730594T SI0936906T1 (en) | 1996-09-18 | 1997-09-15 | Reflux inhibitors |
KR1019997002239A KR100553294B1 (ko) | 1996-09-18 | 1997-09-15 | 역류 억제제 |
KR1020057018539A KR100568659B1 (ko) | 1996-09-18 | 1997-09-15 | 역류 억제제 |
DK97942346T DK0936906T3 (da) | 1996-09-18 | 1997-09-15 | Refluxhæmmere |
CN97199600A CN1117560C (zh) | 1996-09-18 | 1997-09-15 | 反流抑制剂 |
IL12896197A IL128961A (en) | 1996-09-18 | 1997-09-15 | Pharmaceutical preparations containing GABAß receptor agonists and their use as reuptake inhibitors |
EP03013667A EP1344524B1 (en) | 1996-09-18 | 1997-09-15 | Reflux inhibitors |
NZ504244A NZ504244A (en) | 1996-09-18 | 1997-09-15 | Method for the screening of inhibitors of transient lower esophageal sphincter relaxations using a GABAb receptor |
AT97942346T ATE249212T1 (de) | 1996-09-18 | 1997-09-15 | Refluxinhibitoren |
CA002265615A CA2265615C (en) | 1996-09-18 | 1997-09-15 | Reflux inhibitors |
US08/952,400 US6117908A (en) | 1996-09-18 | 1997-09-15 | Use of GABAB receptor agonists as reflux inhibitors |
TR1999/00591T TR199900591T2 (xx) | 1996-09-18 | 1997-09-15 | Geri ak�� �nleyicileri. |
PT03013667T PT1344524E (pt) | 1996-09-18 | 1997-09-15 | Inibidores de refluxo |
SK305-99A SK285744B6 (sk) | 1996-09-18 | 1997-09-15 | Použitie agonistov receptora GABAB ako inhibítorov refluxu |
PCT/SE1997/001555 WO1998011885A1 (en) | 1996-09-18 | 1997-09-15 | Reflux inhibitors |
CZ0093099A CZ299997B6 (cs) | 1996-09-18 | 1997-09-15 | Inhibitory refluxu |
AU44064/97A AU714370B2 (en) | 1996-09-18 | 1997-09-15 | Reflux inhibitors |
EP97942346A EP0936906B1 (en) | 1996-09-18 | 1997-09-15 | Reflux inhibitors |
BR9711400A BR9711400A (pt) | 1996-09-18 | 1997-09-15 | Uso de um agonista receptor gabab ou de um sal farmaceuticamente aceit vel ou de um isÄmero Äptico do dito agonista receptor gabab e processos para a inibi-Æo de relaxamentos do esfincter esofagiano transiente inferior e para a sele-Æo de composto que sÆo inibidores de relaxamentos de esfincter esofagiano transiente inferior |
DE69736445T DE69736445T2 (de) | 1996-09-18 | 1997-09-15 | Refluxinhibitoren |
ES97942346T ES2206749T3 (es) | 1996-09-18 | 1997-09-15 | Inhibidores del reflujo. |
AT03013667T ATE334700T1 (de) | 1996-09-18 | 1997-09-15 | Refluxinhibitoren |
ES03013667T ES2268227T3 (es) | 1996-09-18 | 1997-09-15 | Inhibidores del reflujo. |
PT97942346T PT936906E (pt) | 1996-09-18 | 1997-09-15 | Inibidores do refluxo |
PL97332497A PL190028B1 (pl) | 1996-09-18 | 1997-09-15 | Zastosowanie agonisty receptora GABA |
DK03013667T DK1344524T3 (da) | 1996-09-18 | 1997-09-15 | Refluksinhibitorer |
SI9730749T SI1344524T1 (sl) | 1996-09-18 | 1997-09-15 | Inhibitorji refluksa |
JP51458198A JP4098832B2 (ja) | 1996-09-18 | 1997-09-15 | 逆流抑制剤 |
MYPI97004296A MY122020A (en) | 1996-09-18 | 1997-09-16 | Use of gabab receptor agonists as reflux inhibitors |
SA97180522A SA97180522B1 (ar) | 1996-09-18 | 1997-10-27 | مثبطات الترجيع reflux |
IS5001A IS2329B (is) | 1996-09-18 | 1999-03-15 | Bakflæðishemlar |
NO19991287A NO326837B1 (no) | 1996-09-18 | 1999-03-17 | Anvendelse av GABAB-reseptoragonister for inhibering av transiente relaksjoner av nedre osofagfinkter |
HK00101114A HK1022100A1 (en) | 1996-09-18 | 2000-02-24 | Reflux inhibitors |
US09/658,242 US6664069B1 (en) | 1996-09-18 | 2000-09-08 | Use of GABAB receptor agonists in the screening of compounds which are reflux inhibitors |
HK03109347A HK1057004A1 (en) | 1996-09-18 | 2003-12-23 | Reflux inhibitors |
IS8623A IS2538B (is) | 1996-09-18 | 2007-03-19 | Bakflæðishemlar |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9603408A SE9603408D0 (sv) | 1996-09-18 | 1996-09-18 | Medical use |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9603408D0 true SE9603408D0 (sv) | 1996-09-18 |
Family
ID=20403936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9603408A SE9603408D0 (sv) | 1996-09-18 | 1996-09-18 | Medical use |
Country Status (35)
Country | Link |
---|---|
US (2) | US6117908A (sv) |
EP (2) | EP0936906B1 (sv) |
JP (1) | JP4098832B2 (sv) |
KR (2) | KR100568659B1 (sv) |
CN (1) | CN1117560C (sv) |
AR (1) | AR007747A1 (sv) |
AT (2) | ATE249212T1 (sv) |
AU (1) | AU714370B2 (sv) |
BR (1) | BR9711400A (sv) |
CA (1) | CA2265615C (sv) |
CZ (1) | CZ299997B6 (sv) |
DE (2) | DE69736445T2 (sv) |
DK (2) | DK1344524T3 (sv) |
EE (1) | EE03952B1 (sv) |
ES (2) | ES2268227T3 (sv) |
HK (2) | HK1022100A1 (sv) |
HU (1) | HU224968B1 (sv) |
ID (1) | ID19621A (sv) |
IL (1) | IL128961A (sv) |
IS (2) | IS2329B (sv) |
MY (1) | MY122020A (sv) |
NO (1) | NO326837B1 (sv) |
NZ (2) | NZ504244A (sv) |
PL (1) | PL190028B1 (sv) |
PT (2) | PT1344524E (sv) |
RU (1) | RU2199316C2 (sv) |
SA (1) | SA97180522B1 (sv) |
SE (1) | SE9603408D0 (sv) |
SI (2) | SI0936906T1 (sv) |
SK (1) | SK285744B6 (sv) |
TR (1) | TR199900591T2 (sv) |
TW (1) | TW548104B (sv) |
UA (1) | UA61081C2 (sv) |
WO (1) | WO1998011885A1 (sv) |
ZA (1) | ZA977969B (sv) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69722426T3 (de) | 1996-07-24 | 2015-05-07 | Warner-Lambert Company LLC (n.Ges. des Staates Delaware) | Isobutylgaba und dessen derivate zur schmerzbehandlung |
AU8668598A (en) | 1997-08-20 | 1999-03-08 | University Of Oklahoma, The | Gaba analogs to prevent and treat gastrointestinal damage |
US6127418A (en) * | 1997-08-20 | 2000-10-03 | Warner-Lambert Company | GABA analogs to prevent and treat gastrointestinal damage |
EP0974351A3 (en) * | 1998-04-24 | 2000-12-13 | Jouveinal | Medicament for preventing and treating gastrointestinal damage |
US20080207755A1 (en) * | 2000-05-31 | 2008-08-28 | Pfizer Inc | Alpha 2 Delta Ligands For Fibromyalgia and Other Disorders |
US7164034B2 (en) * | 1999-06-10 | 2007-01-16 | Pfizer Inc. | Alpha2delta ligands for fibromyalgia and other disorders |
SE9904507D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
SE9904508D0 (sv) * | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
US7319095B2 (en) * | 1999-12-09 | 2008-01-15 | Astrazeneca Ab | Use of GABAB receptor agonists |
TWI256314B (en) * | 2000-02-09 | 2006-06-11 | Mitsubishi Pharma Corp | Preventive-therapeutical medicament for gastroesophageal reflux disease |
EP1401423A4 (en) * | 2001-05-29 | 2006-08-16 | Depomed Dev Ltd | METHOD FOR THE TREATMENT OF GASTROÖSOPHAGEAL REFLUX DISEASE AND NURSING ACID BREAKDOWN |
SE0102058D0 (sv) * | 2001-06-08 | 2001-06-08 | Astrazeneca Ab | New Salts II |
SE0102057D0 (sv) * | 2001-06-08 | 2001-06-08 | Astrazeneca Ab | New Salts I |
AR033779A1 (es) * | 2001-06-08 | 2004-01-07 | Astrazeneca Ab | Compuestos utiles en la enfermedad de reflujo |
SE0102055D0 (sv) * | 2001-06-08 | 2001-06-08 | Astrazeneca Ab | New Compounds |
GB0209481D0 (en) * | 2002-04-24 | 2002-06-05 | Novartis Ag | Organic compounds |
SE0201940D0 (sv) * | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New combination II |
SE0201939D0 (sv) * | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New combination |
SE0201943D0 (sv) * | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New use |
US7964609B2 (en) | 2002-06-20 | 2011-06-21 | Astrazeneca Ab | Use of mGluR5 antagonists for the treatment of gerd |
GB0226434D0 (en) * | 2002-11-13 | 2002-12-18 | Astrazeneca Ab | Combination product |
AU2003303040B2 (en) * | 2002-12-13 | 2009-04-23 | Warner-Lambert Company Llc | Pregabalin derivatives for the treatment of fibromyalgia and other disorders |
EP2354120A1 (en) | 2003-08-20 | 2011-08-10 | XenoPort, Inc. | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof |
BRPI0413756A (pt) * | 2003-08-20 | 2006-10-31 | Xenoport Inc | composto, métodos para tratar ou evitar espasticidade ou um sintoma de espasticidade, doença de refluxo gastro-esofágico, vìcio em droga, vìcio em ou abuso de álcool, ou vìcio em ou abuso de nicotina, e tosse ou êmese em um paciente, e, composição farmacêutica |
KR20060120612A (ko) * | 2003-09-12 | 2006-11-27 | 얀센 파마슈티카 엔.브이. | 키메라 gabab 수용체 |
US20050220863A1 (en) * | 2004-04-02 | 2005-10-06 | Chien-Hsuan Han | Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist |
US20050220873A1 (en) * | 2004-04-02 | 2005-10-06 | Chien-Hsuan Han | Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist |
US20050226927A1 (en) * | 2004-04-02 | 2005-10-13 | Impax Laboratories, Inc. | Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist |
US8007827B2 (en) * | 2004-04-02 | 2011-08-30 | Impax Laboratories, Inc. | Pharmaceutical dosage forms having immediate release and/or controlled release properties |
SE0401653D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
WO2006050472A2 (en) * | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids |
US7566738B2 (en) * | 2004-11-03 | 2009-07-28 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use |
WO2006071186A1 (en) * | 2004-12-27 | 2006-07-06 | Astrazeneca Ab | Use of gabab receptor agonists |
KR20080091452A (ko) * | 2005-12-23 | 2008-10-13 | 아스트라제네카 아베 | 위장 장애의 치료를 위한 이미다졸 유도체 |
KR20080090449A (ko) * | 2005-12-23 | 2008-10-08 | 아스트라제네카 아베 | Gerd 및 ibs의 치료를 위한 피라졸 |
EP1968947A1 (en) * | 2005-12-23 | 2008-09-17 | AstraZeneca AB | Gaba-b receptor modulators |
BRPI0620373A2 (pt) * | 2005-12-23 | 2011-11-08 | Astrazeneca Ab | composto e sais farmaceuticamente e farmacologicamente aceitáveis dos mesmos, e enantiÈmeros do composto e sais dos mesmos, uso dos mesmos, opcionalmente em combinação com um agonista do receptor de gabab,e , composição farmaceutica |
CA2631991A1 (en) * | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Heterocyclic gaba-b modulators |
US7585996B2 (en) * | 2006-09-15 | 2009-09-08 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use |
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TW202412754A (zh) * | 2022-06-07 | 2024-04-01 | 瑞士商意梭凱普公司 | 應用於食道黏膜的包含逆流抑制劑的藥物傳遞系統 |
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EP0250572A1 (en) * | 1986-01-03 | 1988-01-07 | The University Of Melbourne | Gastro-oesophageal reflux composition |
NO882881L (no) * | 1988-06-29 | 1990-01-02 | Trond Nilsen | Anordning for lengdekorrugering av metallplater. |
AU5106790A (en) * | 1989-02-03 | 1990-09-05 | Cambridge Neuroscience Research, Inc. | Method of screening and classifying compounds |
GB9117716D0 (en) * | 1991-08-16 | 1991-10-02 | Lynxvale Ltd | Gaba derivatives and their therapeutic application |
EP0713698B1 (en) * | 1992-01-22 | 2002-04-03 | Glaxo Group Limited | Medical use of atypical beta-adrenoceptor agonists |
GB9408064D0 (en) * | 1994-04-22 | 1994-06-15 | Merck Sharp & Dohme | Nucleic acids |
US5491134A (en) * | 1994-09-16 | 1996-02-13 | Bristol-Myers Squibb Company | Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives |
US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
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1996
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1997
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1999
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2000
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2003
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