NO991287L - Refluksinhibitor - Google Patents

Refluksinhibitor

Info

Publication number
NO991287L
NO991287L NO991287A NO991287A NO991287L NO 991287 L NO991287 L NO 991287L NO 991287 A NO991287 A NO 991287A NO 991287 A NO991287 A NO 991287A NO 991287 L NO991287 L NO 991287L
Authority
NO
Norway
Prior art keywords
refluksinhibitor
Prior art date
Application number
NO991287A
Other languages
English (en)
Other versions
NO326837B1 (no
NO991287D0 (no
Inventor
Paul L R Andrews
Anders Lehmann
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20403936&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO991287(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO991287L publication Critical patent/NO991287L/no
Publication of NO991287D0 publication Critical patent/NO991287D0/no
Publication of NO326837B1 publication Critical patent/NO326837B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • G01N33/9426—GABA, i.e. gamma-amino-butyrate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
NO19991287A 1996-09-18 1999-03-17 Anvendelse av GABAB-reseptoragonister for inhibering av transiente relaksjoner av nedre osofagfinkter NO326837B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9603408A SE9603408D0 (sv) 1996-09-18 1996-09-18 Medical use
PCT/SE1997/001555 WO1998011885A1 (en) 1996-09-18 1997-09-15 Reflux inhibitors

Publications (3)

Publication Number Publication Date
NO991287L true NO991287L (no) 1999-03-17
NO991287D0 NO991287D0 (no) 1999-03-17
NO326837B1 NO326837B1 (no) 2009-02-23

Family

ID=20403936

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19991287A NO326837B1 (no) 1996-09-18 1999-03-17 Anvendelse av GABAB-reseptoragonister for inhibering av transiente relaksjoner av nedre osofagfinkter

Country Status (35)

Country Link
US (2) US6117908A (no)
EP (2) EP0936906B1 (no)
JP (1) JP4098832B2 (no)
KR (2) KR100553294B1 (no)
CN (1) CN1117560C (no)
AR (1) AR007747A1 (no)
AT (2) ATE249212T1 (no)
AU (1) AU714370B2 (no)
BR (1) BR9711400A (no)
CA (1) CA2265615C (no)
CZ (1) CZ299997B6 (no)
DE (2) DE69736445T2 (no)
DK (2) DK0936906T3 (no)
EE (1) EE03952B1 (no)
ES (2) ES2268227T3 (no)
HK (2) HK1022100A1 (no)
HU (1) HU224968B1 (no)
ID (1) ID19621A (no)
IL (1) IL128961A (no)
IS (2) IS2329B (no)
MY (1) MY122020A (no)
NO (1) NO326837B1 (no)
NZ (2) NZ334495A (no)
PL (1) PL190028B1 (no)
PT (2) PT936906E (no)
RU (1) RU2199316C2 (no)
SA (1) SA97180522B1 (no)
SE (1) SE9603408D0 (no)
SI (2) SI1344524T1 (no)
SK (1) SK285744B6 (no)
TR (1) TR199900591T2 (no)
TW (1) TW548104B (no)
UA (1) UA61081C2 (no)
WO (1) WO1998011885A1 (no)
ZA (1) ZA977969B (no)

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US6127418A (en) * 1997-08-20 2000-10-03 Warner-Lambert Company GABA analogs to prevent and treat gastrointestinal damage
AU8668598A (en) * 1997-08-20 1999-03-08 University Of Oklahoma, The Gaba analogs to prevent and treat gastrointestinal damage
EP0974351A3 (en) * 1998-04-24 2000-12-13 Jouveinal Medicament for preventing and treating gastrointestinal damage
US7164034B2 (en) 1999-06-10 2007-01-16 Pfizer Inc. Alpha2delta ligands for fibromyalgia and other disorders
US20080207755A1 (en) * 2000-05-31 2008-08-28 Pfizer Inc Alpha 2 Delta Ligands For Fibromyalgia and Other Disorders
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
SE9904507D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
TWI256314B (en) * 2000-02-09 2006-06-11 Mitsubishi Pharma Corp Preventive-therapeutical medicament for gastroesophageal reflux disease
CA2449009A1 (en) * 2001-05-29 2002-12-05 Depomed Development, Ltd Method of treating gastroesophageal reflux disease and nocturnal acid breakthrough
SE0102057D0 (sv) * 2001-06-08 2001-06-08 Astrazeneca Ab New Salts I
SE0102055D0 (sv) * 2001-06-08 2001-06-08 Astrazeneca Ab New Compounds
AR033779A1 (es) * 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
SE0102058D0 (sv) * 2001-06-08 2001-06-08 Astrazeneca Ab New Salts II
GB0209481D0 (en) * 2002-04-24 2002-06-05 Novartis Ag Organic compounds
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201943D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New use
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
US7964609B2 (en) 2002-06-20 2011-06-21 Astrazeneca Ab Use of mGluR5 antagonists for the treatment of gerd
GB0226434D0 (en) * 2002-11-13 2002-12-18 Astrazeneca Ab Combination product
MXPA05006320A (es) * 2002-12-13 2005-08-26 Warner Lambert Co Derivados de pregabalina para el tratamiento de fibromialgia y otros trastornos.
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
WO2005019163A2 (en) 2003-08-20 2005-03-03 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
WO2005026208A2 (en) * 2003-09-12 2005-03-24 Janssen Pharmaceutica N.V. Chimeric gabab receptor
US20050220863A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
US7566738B2 (en) * 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en) * 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
WO2006071186A1 (en) * 2004-12-27 2006-07-06 Astrazeneca Ab Use of gabab receptor agonists
AU2006327315A1 (en) * 2005-12-23 2007-06-28 Astrazeneca Ab Imidazole derivatives for the treatment of gastrointestinal disorders
WO2007073299A1 (en) * 2005-12-23 2007-06-28 Astrazeneca Ab Imidazoles as gaba-b receptor modulators
US20090062365A1 (en) * 2005-12-23 2009-03-05 Udo Bauer Pyrazoles for the Treatment of GERD and IBS
JP2009521426A (ja) * 2005-12-23 2009-06-04 アストラゼネカ・アクチエボラーグ ヘテロ環ｇａｂａ−ｂモジュレーター
BRPI0620464A2 (pt) 2005-12-23 2011-11-16 Astrazeneca Ab composto, composição farmacêutica, uso de um composto, e, método para o tratamento de uma doença
US7585996B2 (en) * 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
ES2739542T3 (es) 2006-12-22 2020-01-31 Ironwood Pharmaceuticals Inc Composiciones que comprenden secuestrantes de ácidos biliares para tratar trastornos esofágicos
TWI369982B (en) * 2007-01-11 2012-08-11 Xenoport Inc Sustained release oral dosage forms of a prodrug of r-baclofen and methods of treatment
KR20100015648A (ko) * 2007-04-18 2010-02-12 아스트라제네카 아베 양성 알로스테릭 ｇａｂａｂ 수용체 조절제 효과를 갖는 크산틴 화합물
US20090041806A1 (en) * 2007-06-15 2009-02-12 Xenoport, Inc. Use of prodrugs of gaba analogs, antispasticity agents, and prodrugs of gaba b receptor agonists for treating spasticity
WO2009014491A1 (en) * 2007-07-25 2009-01-29 Astrazeneca Ab The use of (3-amino-2-fluoropropyl) phosphinic acid for treatment of nerd
WO2009061934A1 (en) * 2007-11-06 2009-05-14 Xenoport, Inc. Use of prodrugs of gaba b agonists for treating neuropathic and musculoskeletal pain
US7868043B2 (en) 2008-01-25 2011-01-11 Xenoport, Inc. Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
WO2009094563A2 (en) * 2008-01-25 2009-07-30 Xenoport, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-b-methyl-hexanoic acids and methods of use
CA2710538A1 (en) * 2008-01-25 2009-07-30 Xenoport, Inc. Crystalline form of a (3s)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
US20100137442A2 (en) * 2008-02-01 2010-06-03 Xenoport, Inc. Sustained Release Particulate Oral Dosage Forms of (R)-Baclofen and Methods of Treatment
WO2009117160A2 (en) * 2008-03-20 2009-09-24 General Mills, Inc. Compound and method for treatment of gastroesophageal reflux
US8299291B2 (en) * 2008-08-07 2012-10-30 Xenoport, Inc. Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
US7989641B2 (en) 2008-08-07 2011-08-02 Xenoport, Inc. Methods of synthesizing N-hydroxysuccinimidyl carbonates
CA2753057C (en) * 2009-03-03 2018-09-11 Xenoport, Inc. Sustained release oral dosage forms of an r-baclofen prodrug
US8344028B2 (en) * 2009-04-17 2013-01-01 Xenoport, Inc. Gamma-amino-butyric acid derivatives as GABAB receptor ligands
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Also Published As

Publication number Publication date
CN1117560C (zh) 2003-08-13
KR100568659B1 (ko) 2006-04-07
TR199900591T2 (xx) 1999-07-21
SA97180522B1 (ar) 2006-04-04
NZ334495A (en) 2000-09-29
ES2268227T3 (es) 2007-03-16
WO1998011885A1 (en) 1998-03-26
ID19621A (id) 1998-07-23
UA61081C2 (uk) 2003-11-17
AU4406497A (en) 1998-04-14
NO326837B1 (no) 2009-02-23
JP2001501604A (ja) 2001-02-06
EP1344524B1 (en) 2006-08-02
CZ299997B6 (cs) 2009-01-14
BR9711400A (pt) 1999-08-17
AR007747A1 (es) 1999-11-10
SI1344524T1 (sl) 2006-12-31
KR20000036185A (ko) 2000-06-26
PT1344524E (pt) 2006-11-30
TW548104B (en) 2003-08-21
HK1022100A1 (en) 2000-07-28
SE9603408D0 (sv) 1996-09-18
DE69736445D1 (de) 2006-09-14
ZA977969B (en) 1998-03-18
SK285744B6 (sk) 2007-07-06
SK30599A3 (en) 2000-01-18
IS2538B (is) 2009-09-15
EP0936906A1 (en) 1999-08-25
JP4098832B2 (ja) 2008-06-11
ATE249212T1 (de) 2003-09-15
SI0936906T1 (en) 2004-02-29
KR20050101237A (ko) 2005-10-20
ES2206749T3 (es) 2004-05-16
IS5001A (is) 1999-03-15
HUP9903825A3 (en) 2001-06-28
IS2329B (is) 2008-01-15
AU714370B2 (en) 1999-12-23
IL128961A0 (en) 2000-02-17
PL190028B1 (pl) 2005-10-31
MY122020A (en) 2006-03-31
HK1057004A1 (en) 2004-03-12
DK0936906T3 (da) 2003-11-24
RU2199316C2 (ru) 2003-02-27
CZ93099A3 (cs) 1999-09-15
NZ504244A (en) 2000-09-29
DE69724809T2 (de) 2004-07-15
US6664069B1 (en) 2003-12-16
DK1344524T3 (da) 2006-10-30
CA2265615C (en) 2007-01-30
PL332497A1 (en) 1999-09-13
DE69736445T2 (de) 2007-03-15
EE9900095A (et) 1999-10-15
EP0936906B1 (en) 2003-09-10
DE69724809D1 (de) 2003-10-16
PT936906E (pt) 2003-12-31
CA2265615A1 (en) 1998-03-26
HU224968B1 (en) 2006-04-28
US6117908A (en) 2000-09-12
HUP9903825A2 (hu) 2001-05-28
EP1344524A1 (en) 2003-09-17
CN1237105A (zh) 1999-12-01
EE03952B1 (et) 2003-02-17
KR100553294B1 (ko) 2006-02-22
IS8623A (is) 2007-03-19
ATE334700T1 (de) 2006-08-15
NO991287D0 (no) 1999-03-17
IL128961A (en) 2004-08-31

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