BR9707467A - 1-Pirazol-3-iletil-4-indol-3-ilpiperdinas - Google Patents

1-Pirazol-3-iletil-4-indol-3-ilpiperdinas

Info

Publication number
BR9707467A
BR9707467A BR9707467A BR9707467A BR9707467A BR 9707467 A BR9707467 A BR 9707467A BR 9707467 A BR9707467 A BR 9707467A BR 9707467 A BR9707467 A BR 9707467A BR 9707467 A BR9707467 A BR 9707467A
Authority
BR
Brazil
Prior art keywords
ylpiperdins
ylethyl
pyrazol
indole
Prior art date
Application number
BR9707467A
Other languages
English (en)
Inventor
Henning Boettcher
Joachim Maerz
Gerd Bartoszyk
Hartmut Greiner
Juergen Harting
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR9707467A publication Critical patent/BR9707467A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
BR9707467A 1996-01-25 1997-01-17 1-Pirazol-3-iletil-4-indol-3-ilpiperdinas BR9707467A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19602505A DE19602505A1 (de) 1996-01-25 1996-01-25 1-(Pyrazol-4-Indol-3-yl)-Piperidine
PCT/EP1997/000187 WO1997027186A1 (de) 1996-01-25 1997-01-17 1-(pyrazol-3-yl-ethyl)-4-(indol-3-yl)-piperidine als das zentralnervensystem beeinflussende mittel

Publications (1)

Publication Number Publication Date
BR9707467A true BR9707467A (pt) 1999-07-20

Family

ID=7783568

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9707467A BR9707467A (pt) 1996-01-25 1997-01-17 1-Pirazol-3-iletil-4-indol-3-ilpiperdinas

Country Status (16)

Country Link
EP (1) EP0879234A1 (pt)
JP (1) JP2000503972A (pt)
KR (1) KR19990081970A (pt)
CN (1) CN1209807A (pt)
AR (1) AR005549A1 (pt)
AU (1) AU715785B2 (pt)
BR (1) BR9707467A (pt)
CA (1) CA2244136A1 (pt)
CZ (1) CZ231898A3 (pt)
DE (1) DE19602505A1 (pt)
HU (1) HUP9900980A2 (pt)
NO (1) NO983439L (pt)
PL (1) PL328228A1 (pt)
SK (1) SK99298A3 (pt)
WO (1) WO1997027186A1 (pt)
ZA (1) ZA97572B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021614A1 (en) * 1999-09-09 2001-03-29 H. Lundbeck A/S 5-aminoalkyl and 5-aminocarbonyl substituted indoles
DE60012213T2 (de) 1999-11-10 2005-07-21 Takeda Chemical Industries, Ltd. Fünfgliedrige n-heterocyclen mit hypoglykämischer und hypolipidemischer wirkung
ES2281434T3 (es) 2000-08-14 2007-10-01 Ortho-Mcneil Pharmaceutical, Inc. Pirazoles sustituidos.
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
MXPA04004443A (es) * 2001-11-14 2004-08-11 Merck Patent Gmbh Derivados de pirazol.
DE602006016147D1 (en) 2005-10-11 2010-09-23 Hoffmann La Roche Imidazobenzdiazepinderivate
US20080015214A1 (en) * 2005-10-24 2008-01-17 Bignan Gilles C 3-piperidin-4-yl-indole orl-1 receptor modulators
TWI548630B (zh) * 2011-04-06 2016-09-11 Lg生命科學有限公司 1-(3-氰基-1-異丙基-吲哚-5-基)吡唑-4-羧酸結晶型及其製造方法
CA3194595A1 (en) * 2020-11-04 2022-05-12 Seok Ju Lee Method for preparing crystalline particles of 1-(3-cyano-1-isopropyl-indole-5-yl)pyrazole-4-carboxylic acid, and pharmaceutical composition comprising same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2060816C3 (de) * 1970-12-10 1980-09-04 Merck Patent Gmbh, 6100 Darmstadt 4-Phenylpiperidinderivate Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen enthaltend diese Verbindungen
DE2258033A1 (de) * 1972-11-27 1974-05-30 Merck Patent Gmbh Verfahren zur herstellung von pyrazolderivaten
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
US5045550A (en) * 1990-09-20 1991-09-03 Warner-Lambert Co. Substituted tetrahydropyridines as central nervous system agents
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine

Also Published As

Publication number Publication date
AR005549A1 (es) 1999-06-23
CA2244136A1 (en) 1997-07-31
HUP9900980A2 (hu) 1999-07-28
PL328228A1 (en) 1999-01-18
KR19990081970A (ko) 1999-11-15
CZ231898A3 (cs) 1998-10-14
AU1443297A (en) 1997-08-20
NO983439L (no) 1998-09-25
CN1209807A (zh) 1999-03-03
JP2000503972A (ja) 2000-04-04
EP0879234A1 (de) 1998-11-25
ZA97572B (en) 1997-08-04
WO1997027186A1 (de) 1997-07-31
AU715785B2 (en) 2000-02-10
NO983439D0 (no) 1998-07-24
SK99298A3 (en) 1999-01-11
DE19602505A1 (de) 1997-07-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A , 6A , 7A , 8A E 9A ANUIDADES.