ZA97572B - 1-pyrazol-3-ylethyl-4-indol-3-ylpiperidines. - Google Patents

1-pyrazol-3-ylethyl-4-indol-3-ylpiperidines.

Info

Publication number
ZA97572B
ZA97572B ZA9700572A ZA97572A ZA97572B ZA 97572 B ZA97572 B ZA 97572B ZA 9700572 A ZA9700572 A ZA 9700572A ZA 97572 A ZA97572 A ZA 97572A ZA 97572 B ZA97572 B ZA 97572B
Authority
ZA
South Africa
Prior art keywords
ylpiperidines
ylethyl
indol
pyrazol
Prior art date
Application number
ZA9700572A
Inventor
Henning Boettcher
Joachim Maerz
Gerd Bartoszyk
Hartmut Greiner
Juergen Harting
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA97572B publication Critical patent/ZA97572B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9700572A 1996-01-25 1997-01-23 1-pyrazol-3-ylethyl-4-indol-3-ylpiperidines. ZA97572B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19602505A DE19602505A1 (en) 1996-01-25 1996-01-25 1- (pyrazol-4-indol-3-yl) piperidines

Publications (1)

Publication Number Publication Date
ZA97572B true ZA97572B (en) 1997-08-04

Family

ID=7783568

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9700572A ZA97572B (en) 1996-01-25 1997-01-23 1-pyrazol-3-ylethyl-4-indol-3-ylpiperidines.

Country Status (16)

Country Link
EP (1) EP0879234A1 (en)
JP (1) JP2000503972A (en)
KR (1) KR19990081970A (en)
CN (1) CN1209807A (en)
AR (1) AR005549A1 (en)
AU (1) AU715785B2 (en)
BR (1) BR9707467A (en)
CA (1) CA2244136A1 (en)
CZ (1) CZ231898A3 (en)
DE (1) DE19602505A1 (en)
HU (1) HUP9900980A2 (en)
NO (1) NO983439L (en)
PL (1) PL328228A1 (en)
SK (1) SK99298A3 (en)
WO (1) WO1997027186A1 (en)
ZA (1) ZA97572B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021614A1 (en) * 1999-09-09 2001-03-29 H. Lundbeck A/S 5-aminoalkyl and 5-aminocarbonyl substituted indoles
ATE271049T1 (en) 1999-11-10 2004-07-15 Takeda Chemical Industries Ltd FIVE-MEMBED N-HETEROCYCLES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
AU8125501A (en) 2000-08-14 2002-02-25 Ortho Mcneil Pharm Inc Substituted pyrazoles
CA2467081A1 (en) * 2001-11-14 2003-05-22 Henning Boettcher Pyrazole derivatives as psychopharmaceuticals
AU2006301377B2 (en) 2005-10-11 2012-03-08 F. Hoffmann-La Roche Ag Imidazo benzodiazepine derivatives
AU2006306497A1 (en) * 2005-10-24 2007-05-03 Janssen Pharmaceutica, N.V. 3-piperidin-4-yl-indole ORL-1 receptor modulators
TWI548630B (en) * 2011-04-06 2016-09-11 Lg生命科學有限公司 1-(3-cyano-1-isopropyl-indol-5-yl)pyrazole-4-carboxylic acid crystalline form and the producing method thereof
EP4218755A4 (en) * 2020-11-04 2024-03-27 Lg Chem, Ltd. Method for preparing crystalline particles of 1-(3-cyano-1-isopropyl-indole-5-yl)pyrazole-4-carboxylic acid, and pharmaceutical composition comprising same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2060816C3 (en) * 1970-12-10 1980-09-04 Merck Patent Gmbh, 6100 Darmstadt 4-Phenylpiperidine derivatives Process for their production and pharmaceutical preparations containing these compounds
DE2258033A1 (en) * 1972-11-27 1974-05-30 Merck Patent Gmbh 3-Heterocyclylalkyl-pyrazoles prodn. - by dehydrogenation or acid elimination from pyrazol(id)ines, useful as CNS depressants
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
US5045550A (en) * 1990-09-20 1991-09-03 Warner-Lambert Co. Substituted tetrahydropyridines as central nervous system agents
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine

Also Published As

Publication number Publication date
CA2244136A1 (en) 1997-07-31
HUP9900980A2 (en) 1999-07-28
SK99298A3 (en) 1999-01-11
AR005549A1 (en) 1999-06-23
PL328228A1 (en) 1999-01-18
AU1443297A (en) 1997-08-20
KR19990081970A (en) 1999-11-15
BR9707467A (en) 1999-07-20
JP2000503972A (en) 2000-04-04
EP0879234A1 (en) 1998-11-25
CN1209807A (en) 1999-03-03
WO1997027186A1 (en) 1997-07-31
NO983439D0 (en) 1998-07-24
NO983439L (en) 1998-09-25
AU715785B2 (en) 2000-02-10
CZ231898A3 (en) 1998-10-14
DE19602505A1 (en) 1997-07-31

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