IL166451A - Processes for the preparation of ultrasound contrast agents - Google Patents

Processes for the preparation of ultrasound contrast agents

Info

Publication number
IL166451A
IL166451A IL166451A IL16645105A IL166451A IL 166451 A IL166451 A IL 166451A IL 166451 A IL166451 A IL 166451A IL 16645105 A IL16645105 A IL 16645105A IL 166451 A IL166451 A IL 166451A
Authority
IL
Israel
Prior art keywords
group
formula
substituent
derivative
production method
Prior art date
Application number
IL166451A
Other languages
English (en)
Other versions
IL166451A0 (en
Original Assignee
Kuraray Co
Eisai R&D Man Co Ltd
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co, Eisai R&D Man Co Ltd, Eisai Co Ltd filed Critical Kuraray Co
Publication of IL166451A0 publication Critical patent/IL166451A0/xx
Publication of IL166451A publication Critical patent/IL166451A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL166451A 2002-07-23 2005-01-23 Processes for the preparation of ultrasound contrast agents IL166451A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002214098A JP4208512B2 (ja) 2002-07-23 2002-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法
PCT/JP2003/009316 WO2004009553A1 (ja) 2002-07-23 2003-07-23 5−(2’−ピリジル)−2−ピリドン誘導体の製造方法

Publications (2)

Publication Number Publication Date
IL166451A0 IL166451A0 (en) 2006-01-15
IL166451A true IL166451A (en) 2011-07-31

Family

ID=30767870

Family Applications (1)

Application Number Title Priority Date Filing Date
IL166451A IL166451A (en) 2002-07-23 2005-01-23 Processes for the preparation of ultrasound contrast agents

Country Status (13)

Country Link
US (1) US7524967B2 (zh)
EP (1) EP1553086B1 (zh)
JP (1) JP4208512B2 (zh)
KR (1) KR101025528B1 (zh)
CN (1) CN100393702C (zh)
AT (1) ATE444952T1 (zh)
AU (1) AU2003252241B2 (zh)
CA (1) CA2493036C (zh)
DE (1) DE60329615D1 (zh)
HK (1) HK1077578B (zh)
IL (1) IL166451A (zh)
MX (1) MXPA05000944A (zh)
WO (1) WO2004009553A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
WO2006107860A2 (en) * 2005-04-04 2006-10-12 Eisai Co., Ltd. Dihydropyridine compounds and compositions for headaches
US7691885B2 (en) * 2005-08-29 2010-04-06 Vertex Pharmaceuticals Incorporated Pyridones useful as inhibitors of kinases
EP1919905B1 (en) 2005-08-29 2011-02-23 Vertex Pharmaceuticals Incorporated 3,5-disubstituted pyrid-2-ones useful as inhibitors of tec family of non-recptor tyrosine kinases
AU2006284900A1 (en) 2005-08-29 2007-03-08 Vertex Pharmaceuticals Incorporated 3, 5-disubstituted pyrid-2-ones useful as inhibitors of Tec family of non-receptor tyrosine kinases
JP4865337B2 (ja) * 2006-01-24 2012-02-01 富士フイルムファインケミカルズ株式会社 2,3’−ビピリジル−6’−オンの製造方法
US20100016603A1 (en) * 2007-01-29 2010-01-21 Fujifilm Finechemicals Co., Ltd. Production process of 2,3'-bipyridyl-6'-one
EP2131828A2 (en) * 2007-03-05 2009-12-16 Eisai R&D Management Co., Ltd. Ampa and nmda receptor antagonists for neurodegenerative diseases
JP2010524844A (ja) * 2007-04-26 2010-07-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 認知症のためのシンナミド化合物
WO2009081872A1 (ja) * 2007-12-21 2009-07-02 Kuraray Co., Ltd. 6-ハロゲノ-3-アリールピリジン誘導体の製造方法
ITMI20111952A1 (it) * 2011-10-27 2013-04-28 Italiana Sint Spa Procedimento per la prepazione di 2-metossi-5-(piridin-2-il)piridina, un intermedio del perampanel
US9096574B2 (en) 2012-01-03 2015-08-04 Mapi Pharma Ltd. Polymorphs of perampanel
ES2646095T3 (es) 2013-07-25 2017-12-12 Teva Pharmaceuticals International Gmbh Proceso para la preparación de perampanel
CN104725301A (zh) * 2013-12-20 2015-06-24 北京蓝贝望生物医药科技股份有限公司 一种1,2-二氢吡啶-2-酮衍生物的制备方法
US10111867B2 (en) 2015-02-17 2018-10-30 Mapi Pharma Ltd. Process and intermediates for the preparation of perampanel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693611A (en) * 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
DE19633746A1 (de) * 1996-08-22 1998-02-26 Basf Ag Substituierte 2-Phenylpyridine
DE19636995A1 (de) * 1996-09-12 1998-03-19 Basf Ag Verfahren zur Herstellung substituierter Phenylpyridine
JP4176201B2 (ja) * 1998-09-02 2008-11-05 株式会社クラレ 5−ハロゲノ−2−置換ピリジンの製造方法
AU7547900A (en) * 1999-10-11 2001-04-23 Pfizer Inc. 5-(2-substituted-5-heterocyclylsulphonylpyrid-3-yl)- dihydropyrazolo(4,3-d)pyrimidin-7-ones as phosphodiesterase inhibitors
US20020045613A1 (en) 2000-04-27 2002-04-18 Heinz Pauls 1-aroyl-piperidinyl benzamidines
EP1300396B1 (en) * 2000-06-12 2009-01-14 Eisai R&D Management Co., Ltd. 1,2-dihydropyridine compounds, process for preparation of the same and use thereof

Also Published As

Publication number Publication date
CN100393702C (zh) 2008-06-11
EP1553086A1 (en) 2005-07-13
WO2004009553A1 (ja) 2004-01-29
US20060004205A1 (en) 2006-01-05
EP1553086B1 (en) 2009-10-07
KR20050019919A (ko) 2005-03-03
MXPA05000944A (es) 2005-10-18
CA2493036C (en) 2011-03-22
DE60329615D1 (de) 2009-11-19
CN1671665A (zh) 2005-09-21
HK1077578A1 (en) 2006-02-17
KR101025528B1 (ko) 2011-04-04
JP2004051592A (ja) 2004-02-19
AU2003252241B2 (en) 2008-12-04
IL166451A0 (en) 2006-01-15
HK1077578B (zh) 2009-03-27
EP1553086A4 (en) 2007-04-25
CA2493036A1 (en) 2004-01-29
AU2003252241A1 (en) 2004-02-09
JP4208512B2 (ja) 2009-01-14
US7524967B2 (en) 2009-04-28
ATE444952T1 (de) 2009-10-15

Similar Documents

Publication Publication Date Title
IL166451A (en) Processes for the preparation of ultrasound contrast agents
JP2012508729A (ja) 置換3−ピリジルメチルアンモニウムブロミドを製造する方法
US6015905A (en) Process for the preparation of 2-(6-substituted pyrid-2-yloxymethyl) phenylacetate
KR0143987B1 (ko) 2-클로로-5-클로로메틸피리딘의 제조방법 및 신규한 중간 생성물
US8742118B2 (en) Methods for preparing intermediates of perampanel
CN101107230B (zh) 5-氯-2,4-二羟基吡啶的制造方法
EP1873145B1 (en) Method for producing nicotinic acid derivative or salt thereof
EP1186597B1 (en) Process for the production of 2-pyridylpyridine derivatives
EP0627421B1 (en) Method of preparing 2-chloro-pyridinemethanol
JP2583062B2 (ja) 複素環化合物の製造法
JP4570057B2 (ja) アリールピリジン誘導体の製造法
CN109824501A (zh) 一种邻位含羧二氟亚甲基的芳基碘化合物及制备方法
US6096894A (en) Production method of 2-(p-alkylphenyl)pyridine compound
KR100359256B1 (ko) 란소프라졸의 개선된 제조방법
JP2847245B2 (ja) ビピリジン誘導体の新規製造法
KR20070106678A (ko) N-(치환된 아릴메틸)-4-치환-4-(이치환된 메틸)피페리딘및 중간체의 제조방법
JP2583061B2 (ja) ピリジン誘導体の新規製造法
JP4287083B2 (ja) 2−または4−モノ置換ピリジンの製造方法並びに4−モノ置換ピリジンまたはその塩の選択的製造方法および分離方法
CN111233739A (zh) 一种制备4-(2’-吲哚基)-1,3-烯炔衍生物的方法
JPH09132565A (ja) 3−(置換アミノメチル)−6−クロロピリジン及びその製造方法
JP2004300058A (ja) トリフルオロメチル基を有するピリジン類の製造方法
JP2001072666A (ja) 2−(p−アルキルフェニル)ピリジン化合物の製造方法
JPH08104674A (ja) ピリジン誘導体の製造法
JP2002326991A (ja) ハロピリジル−アザビシクロヘプタン誘導体の製造のための中間体

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees