IL164838A - Use of substances that bind to the edg receptor for the preparation of a preparation for the treatment of cancer - Google Patents

Use of substances that bind to the edg receptor for the preparation of a preparation for the treatment of cancer

Info

Publication number
IL164838A
IL164838A IL164838A IL16483804A IL164838A IL 164838 A IL164838 A IL 164838A IL 164838 A IL164838 A IL 164838A IL 16483804 A IL16483804 A IL 16483804A IL 164838 A IL164838 A IL 164838A
Authority
IL
Israel
Prior art keywords
preparing
composition
treating cancer
receptor binding
binding agents
Prior art date
Application number
IL164838A
Other languages
English (en)
Hebrew (he)
Other versions
IL164838A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0211261A external-priority patent/GB0211261D0/en
Priority claimed from GB0217150A external-priority patent/GB0217150D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL164838A0 publication Critical patent/IL164838A0/xx
Publication of IL164838A publication Critical patent/IL164838A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL164838A 2002-05-16 2004-10-25 Use of substances that bind to the edg receptor for the preparation of a preparation for the treatment of cancer IL164838A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0211261A GB0211261D0 (en) 2002-05-16 2002-05-16 Organic compounds
US39041102P 2002-06-20 2002-06-20
GB0217150A GB0217150D0 (en) 2002-07-24 2002-07-24 Organic compounds
US44973903P 2003-02-24 2003-02-24
PCT/EP2003/005125 WO2003097028A1 (en) 2002-05-16 2003-05-15 Use of edg receptor binding agents in cancer

Publications (2)

Publication Number Publication Date
IL164838A0 IL164838A0 (en) 2005-12-18
IL164838A true IL164838A (en) 2013-12-31

Family

ID=29554311

Family Applications (3)

Application Number Title Priority Date Filing Date
IL164838A IL164838A (en) 2002-05-16 2004-10-25 Use of substances that bind to the edg receptor for the preparation of a preparation for the treatment of cancer
IL229559A IL229559A0 (en) 2002-05-16 2013-11-21 Use of substances that bind to the edg receptor in cancer
IL229550A IL229550A0 (en) 2002-05-16 2013-11-21 Use of substances that bind to the edg receptor in cancer

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL229559A IL229559A0 (en) 2002-05-16 2013-11-21 Use of substances that bind to the edg receptor in cancer
IL229550A IL229550A0 (en) 2002-05-16 2013-11-21 Use of substances that bind to the edg receptor in cancer

Country Status (22)

Country Link
US (2) US20090209495A1 (enExample)
EP (3) EP1944026B1 (enExample)
JP (3) JP5227492B2 (enExample)
KR (1) KR20120125398A (enExample)
CN (1) CN1652757B (enExample)
AT (1) ATE412408T1 (enExample)
AU (1) AU2003240655B2 (enExample)
BR (1) BR0311173A (enExample)
CA (1) CA2483594C (enExample)
CY (1) CY1108719T1 (enExample)
DE (1) DE60324416D1 (enExample)
DK (1) DK1505959T3 (enExample)
ES (1) ES2316758T3 (enExample)
IL (3) IL164838A (enExample)
MX (1) MXPA04011384A (enExample)
NO (2) NO334074B1 (enExample)
NZ (2) NZ536513A (enExample)
PL (1) PL372103A1 (enExample)
PT (1) PT1505959E (enExample)
SI (1) SI1505959T1 (enExample)
WO (1) WO2003097028A1 (enExample)
ZA (1) ZA200408575B (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20010688A1 (it) 2001-11-21 2003-05-21 Univ Roma Composti immunoregolatori.
KR100836547B1 (ko) 2002-01-11 2008-06-10 상꾜 가부시키가이샤 아미노 알코올 유도체 또는 포스폰산 유도체 및 이들을함유하는 의약 조성물
WO2003104442A1 (en) * 2002-06-07 2003-12-18 Es Cell International Pte Ltd Methods of regulating differentiation in stem cells
EP1602660B1 (en) * 2003-02-18 2011-04-06 Kyorin Pharmaceutical Co., Ltd. Aminophosphonic acid derivatives, addition salts thereof and s1p receptor modulators
GB0500020D0 (en) * 2005-01-04 2005-02-09 Novartis Ag Organic compounds
NZ549162A (en) 2004-02-24 2009-12-24 Sankyo Co Amino-pyrrol alcohol compounds
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
WO2006013948A1 (ja) * 2004-08-04 2006-02-09 Taisho Pharmaceutical Co., Ltd. トリアゾール誘導体
EP1781595A1 (en) 2004-08-13 2007-05-09 Praecis Pharmaceuticals Inc. Methods and compositions for modulating sphingosine-1-phosphate (s1p) receptor activity
SI1812797T1 (sl) * 2004-10-28 2013-06-28 Lpath, Inc. Pripravki in metode zdravljenja ter preprečevanja hiperprolifetarivnih bolezni
GB0513431D0 (en) 2005-06-30 2005-08-10 Kherion Technology Ltd Prophylactic compositions and uses
GT200600350A (es) * 2005-08-09 2007-03-28 Formulaciones líquidas
CN101415691B (zh) 2006-02-03 2011-12-14 大正制药株式会社 三唑衍生物
JP5218737B2 (ja) 2006-02-06 2013-06-26 大正製薬株式会社 スフィンゴシン−１−リン酸結合阻害物質
CN101460197A (zh) * 2006-04-06 2009-06-17 诺瓦提斯公司 有机化合物的组合
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
GB0612721D0 (en) 2006-06-27 2006-08-09 Novartis Ag Organic compounds
EP1923058A1 (en) * 2006-09-26 2008-05-21 Novartis AG Coated pharmaceutical composition comprising an S1P agonist or modulator
WO2008055072A2 (en) * 2006-10-27 2008-05-08 Lpath, Inc. Compositions and methods for treating ocular diseases and conditions
RU2468009C2 (ru) 2007-08-01 2012-11-27 Тайсо Фармасьютикал Ко., Лтд. Ингибитор связывания s1p1
EP2177521A1 (en) 2008-10-14 2010-04-21 Almirall, S.A. New 2-Amidothiadiazole Derivatives
KR20130109254A (ko) * 2008-11-11 2013-10-07 노파르티스 아게 핑골리모드 ｈｃｌ의 결정질 형태
EP2358660A2 (en) 2008-11-11 2011-08-24 Novartis AG Salts of fingolimod
CN105213372A (zh) 2008-12-22 2016-01-06 诺华股份有限公司 S1p受体激动剂的给药方案
PT4098256T (pt) 2008-12-22 2025-04-10 Novartis Ag Regime de dosagem para um agonista do recetor de s1p
EP2202232A1 (en) 2008-12-26 2010-06-30 Laboratorios Almirall, S.A. 1,2,4-oxadiazole derivatives and their therapeutic use
EP2210890A1 (en) 2009-01-19 2010-07-28 Almirall, S.A. Oxadiazole derivatives as S1P1 receptor agonists
KR20120032538A (ko) 2009-07-24 2012-04-05 라티오팜 게엠베하 핀골리모드 염의 제조 방법
EP2305660A1 (en) 2009-09-25 2011-04-06 Almirall, S.A. New thiadiazole derivatives
JP2013505983A (ja) 2009-09-29 2013-02-21 ノバルティス アーゲー Ｓ１ｐ受容体モジュレーターの投与計画
EP2343287A1 (en) 2009-12-10 2011-07-13 Almirall, S.A. New 2-aminothiadiazole derivatives
EP2366702A1 (en) 2010-03-18 2011-09-21 Almirall, S.A. New oxadiazole derivatives
EP2390252A1 (en) 2010-05-19 2011-11-30 Almirall, S.A. New pyrazole derivatives
WO2012071524A1 (en) 2010-11-24 2012-05-31 Ratiopharm Gmbh Arylsulfonate salts of fingolimod and processes for preparation thereof
FR2968556B1 (fr) 2010-12-13 2013-12-27 Centre Nat Rech Scient Inhibiteurs des infections a vih et leurs utilisations
UA114283C2 (uk) 2011-01-07 2017-05-25 Новартіс Аг Композиції імуносупресантів
ES2772258T3 (es) 2011-02-07 2020-07-07 Biogen Ma Inc Agentes moduladores de S1P
MX2014004813A (es) 2011-10-21 2014-05-20 Novartis Ag Regimen de dosificacion para un modulador o agonista del receptor s1p.
KR101889131B1 (ko) * 2011-12-23 2018-09-20 메이지 세이카 파루마 가부시키가이샤 신규 s1p 수용체 조정제
HK1211237A1 (en) 2012-08-06 2016-05-20 Biogen Ma Inc. Compounds that are s1p modulating agents and/or atx modulating agents
EP2879673B1 (en) 2012-08-06 2018-07-25 Biogen MA Inc. 1,5,6-substituted naphthalene derivatives as sphingosine 1 phosphate (S1P) receptor and/or autotaxin (ATX) modulators for treating inflammatory and autoimmune disorders
ES2749467T3 (es) 2012-11-20 2020-03-20 Biogen Ma Inc Agentes moduladores de S1p y/o ATX
US9850206B2 (en) 2012-11-20 2017-12-26 Biogen Ma Inc. S1P and/or ATX modulating agents
AU2014212465B2 (en) 2013-01-29 2018-07-12 Biogen Ma Inc. S1P modulating agents
EP2970302A1 (en) 2013-03-15 2016-01-20 Biogen MA Inc. S1p and/or atx modulating agents
CN103417970A (zh) * 2013-08-15 2013-12-04 泰山医学院 雌激素上调内皮系统保护分子鞘氨醇1-磷酸的应用
WO2016135644A1 (en) 2015-02-26 2016-09-01 Novartis Ag Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
US11434200B2 (en) 2017-03-09 2022-09-06 Novartis Ag Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof
EP3443986A1 (en) 2017-08-17 2019-02-20 AC BioScience Enhancement of chemotherapy efficiency by sphingosine-1-phosphate

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL36730A0 (en) * 1970-05-28 1971-06-23 Chemagro Corp Phosphonamidothioates,their preparation and their use as herbicides and/or plant growth regulators
GB1524747A (en) 1976-05-11 1978-09-13 Ici Ltd Polypeptide
EP0100172B1 (en) 1982-07-23 1987-08-12 Imperial Chemical Industries Plc Amide derivatives
GB8327256D0 (en) 1983-10-12 1983-11-16 Ici Plc Steroid derivatives
GB8517360D0 (en) 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones
IL86632A0 (en) 1987-06-15 1988-11-30 Ciba Geigy Ag Derivatives substituted at methyl-amino nitrogen
US5010099A (en) 1989-08-11 1991-04-23 Harbor Branch Oceanographic Institution, Inc. Discodermolide compounds, compositions containing same and method of preparation and use
NZ243082A (en) 1991-06-28 1995-02-24 Ici Plc 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
AU661533B2 (en) 1992-01-20 1995-07-27 Astrazeneca Ab Quinazoline derivatives
TW225528B (enExample) 1992-04-03 1994-06-21 Ciba Geigy Ag
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5604229A (en) * 1992-10-21 1997-02-18 Yoshitomi Pharmaceutical Industries, Ltd. 2-amino-1,3-propanediol compound and immunosuppressant
WO1994010202A1 (en) 1992-10-28 1994-05-11 Genentech, Inc. Vascular endothelial cell growth factor antagonists
GB9314893D0 (en) 1993-07-19 1993-09-01 Zeneca Ltd Quinazoline derivatives
PL314238A1 (en) 1993-12-17 1996-09-02 Sandoz Ltd Rapamycin derivatives
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
EP0778263B1 (en) 1994-08-22 2002-01-09 Welfide Corporation Benzene compound and medicinal use thereof
CA2216796C (en) 1995-03-30 2003-09-02 Pfizer Inc. Quinazoline derivatives
GB9508538D0 (en) 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
US5747498A (en) 1996-05-28 1998-05-05 Pfizer Inc. Alkynyl and azido-substituted 4-anilinoquinazolines
US5880141A (en) 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
US5843901A (en) 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
ATE228135T1 (de) 1995-06-09 2002-12-15 Novartis Erfind Verwalt Gmbh Rapamycinderivate
KR100437582B1 (ko) 1995-07-06 2004-12-17 노파르티스 아게 피롤로피리미딘및그들의제조방법
US5760041A (en) 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
GB9603095D0 (en) 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives
EA001595B1 (ru) 1996-04-12 2001-06-25 Варнер-Ламберт Компани Необратимые ингибиторы тирозинкиназ
EP0907642B1 (en) 1996-06-24 2005-11-02 Pfizer Inc. Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases
AU735648B2 (en) 1996-07-12 2001-07-12 Ariad Pharmaceuticals, Inc. Materials and method for treating or preventing pathogenic fungal infection
DE19638745C2 (de) 1996-09-11 2001-05-10 Schering Ag Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
AU4342997A (en) 1996-09-13 1998-04-02 Sugen, Inc. Use of quinazoline derivatives for the manufacture of a medicament in the reatment of hyperproliferative skin disorders
EP0837063A1 (en) 1996-10-17 1998-04-22 Pfizer Inc. 4-Aminoquinazoline derivatives
CO4950519A1 (es) 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
SI1319651T1 (en) * 1997-04-04 2005-10-31 Mitsubishi Pharma Corporation 2-Aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor
CO4940418A1 (es) 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
JPH1180026A (ja) 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
TW557297B (en) 1997-09-26 2003-10-11 Abbott Lab Rapamycin analogs having immunomodulatory activity, and pharmaceutical compositions containing same
GB9721069D0 (en) 1997-10-03 1997-12-03 Pharmacia & Upjohn Spa Polymeric derivatives of camptothecin
EP1070080A4 (en) * 1998-03-09 2004-12-29 Smithkline Beecham Corp HUMAN EDG-1c POLYNUCLEOTIDES AND POLYPEPTIDES AND THEIR APPLICATIONS
JP4516690B2 (ja) 1998-08-11 2010-08-04 ノバルティス アーゲー 血管形成阻害活性を有するイソキノリン誘導体
GB9824579D0 (en) 1998-11-10 1999-01-06 Novartis Ag Organic compounds
UA71587C2 (uk) 1998-11-10 2004-12-15 Шерінг Акцієнгезелльшафт Аміди антранілової кислоти та їхнє застосування як лікарських засобів
ATE300957T1 (de) 1998-12-22 2005-08-15 Genentech Inc Antagonisten von vaskular-endothelialen zellwachstumsfaktoren und ihre anwendung
AU766081B2 (en) 1999-03-30 2003-10-09 Novartis Ag Phthalazine derivatives for treating inflammatory diseases
WO2001003739A1 (fr) * 1999-07-12 2001-01-18 Ono Pharmaceutical Co., Ltd. Inhibiteurs de fibrose contenant comme ingredient actif l'agoniste du recepteur de sphingosine-1-phosphate ou la sphingosine-1-phosphate
IL147803A0 (en) 1999-08-24 2002-08-14 Ariad Gene Therapeutics Inc 28-epirapalogs
AU2001231710A1 (en) * 2000-02-09 2001-08-20 Novartis Ag Pyridine derivatives inhibiting angiogenesis and/or vegf receptor tyrosine kinase
SK152003A3 (en) 2000-07-13 2004-07-07 Sankyo Co Amino alcohol derivatives
WO2002018395A1 (en) 2000-08-31 2002-03-07 Merck & Co., Inc. Phosphate derivatives as immunoregulatory agents
US20020156023A1 (en) * 2000-12-06 2002-10-24 Tularik Inc. Lometrexol combination therapy
IL157773A0 (en) 2001-03-26 2004-03-28 Novartis Ag 2-amino-propanol derivatives
JP2002316985A (ja) 2001-04-20 2002-10-31 Sankyo Co Ltd ベンゾチオフェン誘導体
GB0119249D0 (en) 2001-08-07 2001-10-03 Novartis Ag Organic compounds
WO2003029184A1 (en) 2001-09-27 2003-04-10 Kyorin Pharmaceutical Co., Ltd. Diaryl ether derivative, addition salt thereof, and immunosuppressant
CN1329372C (zh) 2001-09-27 2007-08-01 杏林制药株式会社 二芳基硫醚衍生物及其加成盐和免疫抑制剂

Also Published As

Publication number Publication date
IL229550A0 (en) 2014-01-30
HK1073606A1 (en) 2005-10-14
PL372103A1 (en) 2005-07-11
EP1944026B1 (en) 2013-06-26
NO20045312L (no) 2004-12-03
ZA200408575B (en) 2005-07-27
HK1126127A1 (en) 2009-08-28
SI1505959T1 (sl) 2009-04-30
NZ560662A (en) 2009-09-25
BR0311173A (pt) 2005-03-15
ATE412408T1 (de) 2008-11-15
CA2483594A1 (en) 2003-11-27
EP1955696A2 (en) 2008-08-13
CY1108719T1 (el) 2014-04-09
KR20120125398A (ko) 2012-11-14
PT1505959E (pt) 2009-02-05
US20090209495A1 (en) 2009-08-20
WO2003097028A1 (en) 2003-11-27
CN1652757A (zh) 2005-08-10
EP1955696B1 (en) 2014-05-28
NO20130106L (no) 2004-12-03
US20140303257A1 (en) 2014-10-09
DE60324416D1 (de) 2008-12-11
EP1944026A2 (en) 2008-07-16
JP5227492B2 (ja) 2013-07-03
AU2003240655B2 (en) 2007-09-06
AU2003240655A1 (en) 2003-12-02
NO334074B1 (no) 2013-12-02
CA2483594C (en) 2011-02-15
MXPA04011384A (es) 2005-02-14
CN1652757B (zh) 2012-02-08
EP1505959A1 (en) 2005-02-16
JP2005529921A (ja) 2005-10-06
JP2010100637A (ja) 2010-05-06
EP1505959B1 (en) 2008-10-29
ES2316758T3 (es) 2009-04-16
DK1505959T3 (da) 2009-02-23
IL229559A0 (en) 2014-01-30
NZ536513A (en) 2007-10-26
IL164838A0 (en) 2005-12-18
EP1944026A3 (en) 2011-06-01
JP2013136584A (ja) 2013-07-11
EP1955696A3 (en) 2011-05-25

Similar Documents

Publication Publication Date Title
IL164838A (en) Use of substances that bind to the edg receptor for the preparation of a preparation for the treatment of cancer
EP1487436A4 (en) POLYTHERAPY FOR TREATING, PREVENTING OR MANAGING PROLIFERATIVE DISORDERS AND CANCERS
TWI372628B (en) Methods of modulating cytokine activity; related reagents
HUP0201436A3 (en) Methods and compositions for treating solid tumors
YU42302A (sh) Agonisti beta2-adrenergičnih receptora
EP1226823A3 (en) Method of treating certain cancers using an estrogen agonist/antagonist
AU2001227966A1 (en) Methods for treating tumors
NZ333399A (en) Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis
AU2002339865A1 (en) Methods and compositions useful for diagnosis, staging, and treatment of cancers and tumors
AU2002340139A1 (en) Inhibitors of the egf receptor for the treatment of thyroid cancer
WO2000004954A3 (de) Neue urokinase-inhibitoren
AU2003290059A8 (en) Use of cd137 antagonists for the treatment of tumors
DK1079851T3 (da) Anvendelse af anti-prolactinmidler til behandling af cancer
EP0943620A3 (en) Betulinic acid derivatives for inhibiting cancer growth
GB2348899B (en) Surface treatment for tungsten carbide insert
HUP0101947A3 (en) Combination for the treatment of tumors
WO2000037065A3 (en) Endocrine therapy for breast cancer: combined treatment with tamoxifen plus alkyl pcdfs
AU1700700A (en) Compounds, antibodies and methods for treating, preventing or diagnosing tumour metastasis
ZA200005575B (en) Preparation of an aqueous composition for treating leather.
AU1991901A (en) Pharmaceutical composition for treating and preventing human tumors, which express the tumor antigen mucin and/or the carcinoembryonic antigen (cea), and the use thereof
HUP0103557A3 (en) Use of an anthracycline derivative for the treatment of a liver tumor
AU2228299A (en) Composition and method for treating metastatic tumors or cancer induced by cellsexpressing sv40 tumor antigen
GB9825436D0 (en) Door pad (or shoe blotter)
GB2379444A9 (en) Assay for cancer of the prostate
AU5802200A (en) Agent for gene therapy and for the prevention of metastases, as well as for the gene therapy of tumors

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees