AU2003240655B2 - Use of EDG receptor binding agents in cancer - Google Patents

Use of EDG receptor binding agents in cancer Download PDF

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Publication number
AU2003240655B2
AU2003240655B2 AU2003240655A AU2003240655A AU2003240655B2 AU 2003240655 B2 AU2003240655 B2 AU 2003240655B2 AU 2003240655 A AU2003240655 A AU 2003240655A AU 2003240655 A AU2003240655 A AU 2003240655A AU 2003240655 B2 AU2003240655 B2 AU 2003240655B2
Authority
AU
Australia
Prior art keywords
alkyl
inhibitor
compound
halogen
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003240655A
Other languages
English (en)
Other versions
AU2003240655A1 (en
Inventor
Thomas Baumruker
Volker Brinkmann
Kenneth Richard La Montagne
Peter T. Lassota
Diana Mechtcheriakova
Jeanette Marjorie Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0211261A external-priority patent/GB0211261D0/en
Priority claimed from GB0217150A external-priority patent/GB0217150D0/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2003240655A1 publication Critical patent/AU2003240655A1/en
Application granted granted Critical
Publication of AU2003240655B2 publication Critical patent/AU2003240655B2/en
Priority to AU2007237378A priority Critical patent/AU2007237378B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2003240655A 2002-05-16 2003-05-15 Use of EDG receptor binding agents in cancer Ceased AU2003240655B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2007237378A AU2007237378B2 (en) 2002-05-16 2007-12-05 Use of EDG receptor binding agents in cancer

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0211261.3 2002-05-16
GB0211261A GB0211261D0 (en) 2002-05-16 2002-05-16 Organic compounds
US39041102P 2002-06-20 2002-06-20
US60/390,411 2002-06-20
GB0217150.2 2002-07-24
GB0217150A GB0217150D0 (en) 2002-07-24 2002-07-24 Organic compounds
US44973903P 2003-02-24 2003-02-24
US60/449,739 2003-02-24
PCT/EP2003/005125 WO2003097028A1 (en) 2002-05-16 2003-05-15 Use of edg receptor binding agents in cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2007237378A Division AU2007237378B2 (en) 2002-05-16 2007-12-05 Use of EDG receptor binding agents in cancer

Publications (2)

Publication Number Publication Date
AU2003240655A1 AU2003240655A1 (en) 2003-12-02
AU2003240655B2 true AU2003240655B2 (en) 2007-09-06

Family

ID=29554311

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003240655A Ceased AU2003240655B2 (en) 2002-05-16 2003-05-15 Use of EDG receptor binding agents in cancer

Country Status (22)

Country Link
US (2) US20090209495A1 (enExample)
EP (3) EP1505959B1 (enExample)
JP (3) JP5227492B2 (enExample)
KR (1) KR20120125398A (enExample)
CN (1) CN1652757B (enExample)
AT (1) ATE412408T1 (enExample)
AU (1) AU2003240655B2 (enExample)
BR (1) BR0311173A (enExample)
CA (1) CA2483594C (enExample)
CY (1) CY1108719T1 (enExample)
DE (1) DE60324416D1 (enExample)
DK (1) DK1505959T3 (enExample)
ES (1) ES2316758T3 (enExample)
IL (3) IL164838A (enExample)
MX (1) MXPA04011384A (enExample)
NO (2) NO334074B1 (enExample)
NZ (2) NZ560662A (enExample)
PL (1) PL372103A1 (enExample)
PT (1) PT1505959E (enExample)
SI (1) SI1505959T1 (enExample)
WO (1) WO2003097028A1 (enExample)
ZA (1) ZA200408575B (enExample)

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JP6033791B2 (ja) * 2011-12-23 2016-11-30 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 新規ｓ１ｐ受容体調整薬
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Also Published As

Publication number Publication date
ATE412408T1 (de) 2008-11-15
PL372103A1 (en) 2005-07-11
HK1126127A1 (en) 2009-08-28
JP2005529921A (ja) 2005-10-06
EP1944026A3 (en) 2011-06-01
NO20130106L (no) 2004-12-03
EP1955696B1 (en) 2014-05-28
CA2483594A1 (en) 2003-11-27
EP1944026B1 (en) 2013-06-26
IL164838A (en) 2013-12-31
HK1073606A1 (en) 2005-10-14
NZ536513A (en) 2007-10-26
CN1652757B (zh) 2012-02-08
MXPA04011384A (es) 2005-02-14
EP1955696A3 (en) 2011-05-25
ZA200408575B (en) 2005-07-27
US20090209495A1 (en) 2009-08-20
PT1505959E (pt) 2009-02-05
JP5227492B2 (ja) 2013-07-03
EP1505959A1 (en) 2005-02-16
CA2483594C (en) 2011-02-15
SI1505959T1 (sl) 2009-04-30
WO2003097028A1 (en) 2003-11-27
JP2010100637A (ja) 2010-05-06
NO334074B1 (no) 2013-12-02
EP1505959B1 (en) 2008-10-29
KR20120125398A (ko) 2012-11-14
CN1652757A (zh) 2005-08-10
EP1944026A2 (en) 2008-07-16
EP1955696A2 (en) 2008-08-13
JP2013136584A (ja) 2013-07-11
ES2316758T3 (es) 2009-04-16
CY1108719T1 (el) 2014-04-09
DE60324416D1 (de) 2008-12-11
NZ560662A (en) 2009-09-25
BR0311173A (pt) 2005-03-15
IL164838A0 (en) 2005-12-18
IL229559A0 (en) 2014-01-30
IL229550A0 (en) 2014-01-30
US20140303257A1 (en) 2014-10-09
DK1505959T3 (da) 2009-02-23
AU2003240655A1 (en) 2003-12-02
NO20045312L (no) 2004-12-03

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