IL160136A0 - Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds - Google Patents

Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds

Info

Publication number
IL160136A0
IL160136A0 IL16013602A IL16013602A IL160136A0 IL 160136 A0 IL160136 A0 IL 160136A0 IL 16013602 A IL16013602 A IL 16013602A IL 16013602 A IL16013602 A IL 16013602A IL 160136 A0 IL160136 A0 IL 160136A0
Authority
IL
Israel
Prior art keywords
preparation
growth regulators
cosmetic preparations
preparations
drugs
Prior art date
Application number
IL16013602A
Other languages
English (en)
Original Assignee
Ustav Ex Botan Akademie Ved Ce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ustav Ex Botan Akademie Ved Ce filed Critical Ustav Ex Botan Akademie Ved Ce
Publication of IL160136A0 publication Critical patent/IL160136A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Dentistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Environmental Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
IL16013602A 2001-08-02 2002-08-01 Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds IL160136A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20012818A CZ294535B6 (cs) 2001-08-02 2001-08-02 Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
PCT/CZ2002/000045 WO2003040144A2 (en) 2001-08-02 2002-08-01 Heterocyclic compound based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds

Publications (1)

Publication Number Publication Date
IL160136A0 true IL160136A0 (en) 2004-06-20

Family

ID=5473504

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16013602A IL160136A0 (en) 2001-08-02 2002-08-01 Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds

Country Status (20)

Country Link
US (2) US7279482B2 (hu)
EP (1) EP1419157B1 (hu)
JP (1) JP2005508386A (hu)
KR (1) KR100939147B1 (hu)
CN (1) CN1556808B (hu)
AU (3) AU2002363362B2 (hu)
BR (1) BR0211597A (hu)
CA (1) CA2455972C (hu)
CZ (1) CZ294535B6 (hu)
HU (1) HUP0401407A3 (hu)
IL (1) IL160136A0 (hu)
MX (1) MXPA04000936A (hu)
NO (1) NO329434B1 (hu)
NZ (1) NZ531086A (hu)
PL (1) PL368299A1 (hu)
RS (1) RS52389B (hu)
RU (1) RU2302421C2 (hu)
SG (2) SG119228A1 (hu)
WO (1) WO2003040144A2 (hu)
ZA (1) ZA200401461B (hu)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2396276A1 (en) * 2000-01-07 2001-07-12 Universitaire Instelling Antwerpen Purine derivatives, process for their preparation and use thereof
FR2818642B1 (fr) * 2000-12-26 2005-07-15 Hoechst Marion Roussel Inc Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion
CZ294535B6 (cs) * 2001-08-02 2005-01-12 Ústav Experimentální Botaniky Avčr Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
CA2501999A1 (en) * 2002-10-15 2004-04-29 Irm Llc Compositions and methods for inducing osteogenesis
MXPA06001758A (es) * 2003-08-15 2006-08-11 Irm Llc Anilino purinas sustituidas en la posicion 6 utiles como inhibidores de rtk.
AU2011213790B2 (en) * 2003-10-03 2013-05-02 The General Hospital Corporation Methods for altering mRNA splicing and treating familial dysautonomia and other mechanistically related disorders
WO2005033290A2 (en) 2003-10-03 2005-04-14 The General Hospital Corporation Methods for altering mrna splicing and treating familial dysautonomia and other mechanistically related disorders
AU2008210904A1 (en) * 2007-01-26 2008-08-07 Irm Llc Purine compounds and compositions as kinase inhibitors for the treatment of Plasmodium related diseases
CN101646669B (zh) * 2007-03-28 2013-09-04 神经研究公司 嘌呤基衍生物及其作为钾通道调节剂的用途
CZ302225B6 (cs) * 2007-07-04 2010-12-29 Univerzita Palackého v Olomouci Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny
CZ300774B6 (cs) * 2007-10-05 2009-08-05 Univerzita Palackého Substituované 6-(alkylbenzylamino)purinové deriváty pro použití jako antagonisté cytokininových receptoru a prípravky obsahující tyto slouceniny
EP3912973A3 (en) * 2007-11-28 2022-02-16 Dana-Farber Cancer Institute, Inc. Small molecule myristate inhibitors of bcr-abl and methods of use
CZ302623B6 (cs) 2009-04-22 2011-08-03 Univerzita Palackého Oxalátokomplexy platiny s deriváty N6-benzyladeninu, zpusob jejich prípravy a použití techto komplexu jako léciv v protinádorové terapii
PE20120493A1 (es) 2009-06-29 2012-05-20 Incyte Corp Pirimidinonas como inhibidores de pi3k
CZ302618B6 (cs) 2009-09-10 2011-08-03 Univerzita Palackého Cyklobutan-1,1-dikarboxylátokomplexy platiny s deriváty N6-benzyladeninu, zpusoby jejich prípravy a použití techto komplexu jako léciv v protinádorové terapii
JP5818266B2 (ja) * 2009-09-29 2015-11-18 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム ジヒドロオロット酸デヒドロゲナーゼの阻害剤である抗マラリア剤
US8680108B2 (en) * 2009-12-18 2014-03-25 Incyte Corporation Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors
US8759359B2 (en) * 2009-12-18 2014-06-24 Incyte Corporation Substituted heteroaryl fused derivatives as PI3K inhibitors
CA2796311A1 (en) 2010-04-14 2011-10-20 Incyte Corporation Fused derivatives as pi3k.delta. inhibitors
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
CZ2010670A3 (cs) * 2010-09-07 2012-03-14 Univerzita Palackého v Olomouci Použití 6-substituovaných 9-halogenalkyl purinu pro regulaci rustu a vývoje rostlin, rostlinných orgánu a bunek, nové 6-substituované 9-halogenalkyl puriny
AR084366A1 (es) 2010-12-20 2013-05-08 Incyte Corp N-(1-(fenil sustituido)etil)-9h-purin-6-aminas como inhibidores de pi3k
WO2012125629A1 (en) 2011-03-14 2012-09-20 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
US9126948B2 (en) 2011-03-25 2015-09-08 Incyte Holdings Corporation Pyrimidine-4,6-diamine derivatives as PI3K inhibitors
WO2012142029A2 (en) 2011-04-10 2012-10-18 Florida A&M University Serms for the treatment of estrogen receptor-mediated disorders
KR101982475B1 (ko) 2011-09-02 2019-05-27 인사이트 홀딩스 코포레이션 Ｐｉ３ｋ 억제제로서 헤테로시클릴아민
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
EP2912256B1 (en) 2012-10-26 2019-03-13 Exxonmobil Upstream Research Company Downhole flow control, joint assembly and method
CZ306894B6 (cs) 2013-02-08 2017-08-30 Univerzita PalackĂ©ho v Olomouci 2-Substituované-6-biarylmethylamino-9-cyklopentyl-9H-purinové deriváty, jejich použití jako léčiva a farmaceutické přípravky tyto sloučeniny obsahující
US9938279B2 (en) * 2013-04-09 2018-04-10 Energenesis Biomedical Co., Ltd Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)
RU2529817C1 (ru) * 2013-07-08 2014-09-27 Владимир Иванович Петров 9-[2-(4-изопропилфенокси)этил]аденин, обладающий антидепрессантным и противострессорным действием
US9816361B2 (en) 2013-09-16 2017-11-14 Exxonmobil Upstream Research Company Downhole sand control assembly with flow control, and method for completing a wellbore
CN108703970A (zh) * 2013-09-18 2018-10-26 华安医学股份有限公司 一种活化ampk的化合物及其用途
WO2015191677A1 (en) 2014-06-11 2015-12-17 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
CZ306984B6 (cs) 2014-12-15 2017-11-01 Ústav experimentální botaniky AV ČR, v. v. i. 6,8-Disubstituované-9-(heterocyklyl)puriny, přípravky obsahující tyto deriváty a jejich použití v kosmetických a medicínských aplikacích
PT3244891T (pt) 2015-01-16 2022-10-20 Massachusetts Gen Hospital Compostos para melhorar o splicing do arnm
MY187502A (en) 2015-02-27 2021-09-24 Incyte Corp Salts of pi3k inhibitor and processes for their preparation
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
US9732097B2 (en) 2015-05-11 2017-08-15 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
EP3528816A4 (en) * 2016-10-21 2020-04-08 Nimbus Lakshmi, Inc. TYK2 INHIBITORS AND USES THEREOF
CN106632338B (zh) * 2016-12-16 2018-11-27 温州医科大学 一种9-取代-n-（2-氯苄基）嘌呤-6-胺类衍生物及其制备方法和应用
CN106632339B (zh) * 2016-12-16 2018-11-27 温州医科大学 一种6-取代-9h-嘌呤类衍生物及其制备方法和应用
CA3057978A1 (en) 2017-03-27 2018-10-04 The Regents Of The University Of California Compositions and method of treating cancer
CZ307868B6 (cs) 2017-04-28 2019-07-10 Univerzita PalackĂ©ho v Olomouci Deriváty 9-(2-oxacykloalkyl)-9H-purin-2,6-diaminu, přípravky obsahující tyto deriváty a jejich použití
JP6510621B2 (ja) * 2017-11-29 2019-05-08 華安醫學股分有限公司Ｅｎｅｒｇｅｎｅｓｉｓ Ｂｉｏｍｅｄｉｃａｌ Ｃｏ．， Ｌｔｄ． 活性化ａｍｐｋの化合物及びその使用
CN107903274A (zh) * 2017-12-28 2018-04-13 窦玉玲 一种胺类化合物及其在抗肿瘤药物中的应用
JP6877479B2 (ja) * 2019-04-04 2021-05-26 華安醫學股分有限公司Ｅｎｅｒｇｅｎｅｓｉｓ Ｂｉｏｍｅｄｉｃａｌ Ｃｏ．， Ｌｔｄ． 活性化ａｍｐｋの化合物及びその使用
CZ308865B6 (cs) 2020-05-17 2021-07-21 Ústav experimentální botaniky AV ČR, v. v. i. Mesylátová sůl para-topolinu, přípravky ji obsahující, a její použití
CN111777612B (zh) * 2020-06-05 2022-04-19 广东达元绿洲食品安全科技股份有限公司 一种6-苄基腺嘌呤半抗原、人工抗原及其在免疫检测中的应用
WO2022012702A1 (en) 2020-07-13 2022-01-20 Univerzita Palackeho V Olomouci Nitrogen heterocyclic cytokinin derivatives, compositions containing these derivatives and use thereof
CN112656800A (zh) * 2021-02-09 2021-04-16 中国科学院昆明动物研究所 巯嘌呤及其衍生物在制备解除恶性肿瘤免疫抑制药物中的用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3041340A (en) * 1962-06-26 Method of preparing substituted
US2956998A (en) * 1960-10-18 Adenine derivatives and process
US3213095A (en) * 1963-04-04 1965-10-19 American Cyanamid Co N-benzylation of adenine
US3321293A (en) * 1964-04-29 1967-05-23 Union Carbide Corp Method of defoliating cotton plants
JPH0690429B2 (ja) * 1986-05-26 1994-11-14 コニカ株式会社 直接ポジ型ハロゲン化銀写真感光材料
US5371089A (en) * 1987-02-26 1994-12-06 Senetek, Plc Method and composition for ameliorating the adverse effects of aging
US5164394A (en) * 1989-06-08 1992-11-17 Senetek, Plc Method for treating hyperproliferative skin diseases
EP0584068B2 (en) * 1991-05-16 2004-04-28 Senetek, Plc Method and composition for ameliorating the adverse effects of aging
JP2636118B2 (ja) * 1991-09-10 1997-07-30 三省製薬株式会社 育毛剤
AU659861B2 (en) * 1991-09-10 1995-06-01 Sansho Seiyaku Co., Ltd. Preparation for promoting hair growth
JPH07233037A (ja) * 1993-12-29 1995-09-05 Sansho Seiyaku Co Ltd 皮膚化粧料
CA2223081C (en) * 1995-06-07 2001-03-06 Pfizer Inc. Heterocyclic ring-fused pyrimidine derivatives
US6498163B1 (en) * 1997-02-05 2002-12-24 Warner-Lambert Company Pyrido[2,3-D]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation
CA2396276A1 (en) * 2000-01-07 2001-07-12 Universitaire Instelling Antwerpen Purine derivatives, process for their preparation and use thereof
CZ294535B6 (cs) * 2001-08-02 2005-01-12 Ústav Experimentální Botaniky Avčr Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
US20060166295A1 (en) * 2002-07-01 2006-07-27 James Woods Method for determination of likelihood of occurrence of preterm labor in pregnant females

Also Published As

Publication number Publication date
AU2008203838A1 (en) 2008-09-04
HUP0401407A2 (hu) 2004-11-29
EP1419157B1 (en) 2013-11-27
AU2002363362B2 (en) 2008-05-22
US7279482B2 (en) 2007-10-09
CZ20012818A3 (cs) 2003-03-12
CN1556808A (zh) 2004-12-22
SG119228A1 (en) 2006-02-28
WO2003040144A2 (en) 2003-05-15
NO329434B1 (no) 2010-10-18
WO2003040144A3 (en) 2004-02-26
BR0211597A (pt) 2004-07-13
CA2455972C (en) 2012-01-03
SG127738A1 (en) 2006-12-29
AU2008203837A1 (en) 2008-09-04
NZ531086A (en) 2005-12-23
HUP0401407A3 (en) 2007-05-29
RU2302421C2 (ru) 2007-07-10
KR20050016267A (ko) 2005-02-21
YU8904A (sh) 2006-08-17
US20050043328A1 (en) 2005-02-24
CN1556808B (zh) 2010-04-28
JP2005508386A (ja) 2005-03-31
ZA200401461B (en) 2005-08-31
MXPA04000936A (es) 2005-02-17
CA2455972A1 (en) 2003-05-15
KR100939147B1 (ko) 2010-01-28
PL368299A1 (en) 2005-03-21
NO20040469L (no) 2004-04-30
US20080014227A1 (en) 2008-01-17
CZ294535B6 (cs) 2005-01-12
RU2004105843A (ru) 2005-07-10
RS52389B (en) 2013-02-28
US8552013B2 (en) 2013-10-08
AU2008203838B2 (en) 2011-09-01
EP1419157A2 (en) 2004-05-19

Similar Documents

Publication Publication Date Title
IL160136A0 (en) Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds
AU2003294608A8 (en) Substitution derivatives of n6-benzyladenosine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds
PT1412384E (pt) Formulação estável de glp-1 modificado
HUP0203477A3 (en) Alkylamino substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase, pharmaceutical compositions containing them and their preparations
NO20016185L (no) Bicykliske heterocykler, medikamenter inneholdende disse forbindelser, deres anvendelse og fremgangsmåte for fremstillingderav
HUP0204226A3 (en) Quinazoline derivatives, pharmaceutical compositions containing them, their use and process for the preparation of the compounds
WO2003099771A3 (en) Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
HUP0402191A3 (en) Acetylene derivatives having human matabotropic glutamate receptor antagonistic activity, process for producing them, pharmaceutical compositions containing them and use thereof
PL352547A1 (en) Drugs containing inhibitors of human kinase h-sgk
NO20040268L (no) Nye 2H-pyridazin-3-derivater, farmasoytiske preparater inneholdende slike og fremgangsmate for fremstilling av den aktive ingrediensen
HUP0203385A3 (en) Pyrimidine derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0401654A3 (en) Heterokondensated pyrimidine derivatives, their intermediates, preparations of the compounds and pharmaceutical compositions containing them
HUP9903353A3 (en) 7alpha-(methyl-amino-pentyl)-estratrienes, pharmaceutical preparations which contain said 7alpha-(5-methylaminopentyl) -estratrienes and use thereof for production of drugs
HUP0400317A3 (en) Beta-carboline derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0303977A3 (en) Procedure for the preparation of pure phosphatides and their use in the cosmetic, pharmaceutical nad alimentary fields
HUP0303045A3 (en) Pyrimidine derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0500958A2 (en) 2-arylimino-2,3-dihydrothiazole derivatives, methods for preparing them, therapeutic use thereof and pharmaceutical compositions containing them
HK1065305A1 (en) Substituted 4-aminocyclohexanol derivatives
NO20023249D0 (no) Nye substituerte pyrazolo(4,3-e)ediazepiner, farmasöytiske preparater inneholdende disse, anvendelse som medisinske produkterog fremgangsmåter for fremstilling derav
PL369632A1 (en) Novel 5-thio-ss-d-xylopyranoside derivatives, preparation method thereof, pharmaceutical compositions containing same and the therapeutic use thereof
AU4535800A (en) Novel 6-phenylpurine 9-beta-d-ribonucleosides with antineoplastic activity, their use for preparing pharmaceutical compositions and pharmaceutical preparations containing such compounds
NO20021527L (no) Pyrimidinderivater, fremgangsmåte for fremstilling av derivatene og legemidler inneholdende de samme som den aktivebestanddel
PL352029A1 (en) 14-beta-h-sterols, pharmaceutical compositions containing these sterols and use of these derivatives for obtaining drugs to regulate meioses
MXPA03003198A (es) 3,4-dihidro-pirido [1,2-a]pirimidinas sustituidas.
IL160160A0 (en) SUBSTITUTED 5,6,6a, 11b-TETRAHYDRO-7-OXA-5-AZA-BENZO[c]FLUORENE-6-CARBOXYLIC ACID DERIVATIVES SERVING AS NMDA ANTAGONISTS