MXPA03003198A - 3,4-dihidro-pirido [1,2-a]pirimidinas sustituidas. - Google Patents

3,4-dihidro-pirido [1,2-a]pirimidinas sustituidas.

Info

Publication number
MXPA03003198A
MXPA03003198A MXPA03003198A MXPA03003198A MXPA03003198A MX PA03003198 A MXPA03003198 A MX PA03003198A MX PA03003198 A MXPA03003198 A MX PA03003198A MX PA03003198 A MXPA03003198 A MX PA03003198A MX PA03003198 A MXPA03003198 A MX PA03003198A
Authority
MX
Mexico
Prior art keywords
compounds
pyrido
dihydro
substituted
pyrimidines
Prior art date
Application number
MXPA03003198A
Other languages
English (en)
Inventor
Matthias Gerlach
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of MXPA03003198A publication Critical patent/MXPA03003198A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

La invencion se refiere a 3,4-dihidro-pirido[1,2-alpirimidinas sustituidas de estructura general (I), a metodos para su produccion, a bibliotecas de sustancias que contienen estos compuestos, a medicamentos que contienen estos compuestos, al uso de estos compuestos para la elaboracion de medicamentos para el tratamiento de dolores, incontinencia urinaria, comezon, tinnitus aurium y/o diarrea, asi como a preparaciones farmaceuticas que contienen estos compuestos.
MXPA03003198A 2000-10-13 2001-10-10 3,4-dihidro-pirido [1,2-a]pirimidinas sustituidas. MXPA03003198A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10050662A DE10050662A1 (de) 2000-10-13 2000-10-13 Substituierte 3,4-Dihydro-pyrido[1,2-a]pyrimidine
PCT/EP2001/011700 WO2002030933A1 (de) 2000-10-13 2001-10-10 Substituierte 3,4-dihydro-pyrido[1,2-a]pyrimidine

Publications (1)

Publication Number Publication Date
MXPA03003198A true MXPA03003198A (es) 2004-05-21

Family

ID=7659597

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03003198A MXPA03003198A (es) 2000-10-13 2001-10-10 3,4-dihidro-pirido [1,2-a]pirimidinas sustituidas.

Country Status (27)

Country Link
US (1) US7230103B2 (es)
EP (1) EP1326866B1 (es)
JP (1) JP4315678B2 (es)
KR (1) KR20030036924A (es)
CN (1) CN1255407C (es)
AR (1) AR034266A1 (es)
AT (1) ATE297927T1 (es)
AU (2) AU2002210526B2 (es)
BR (1) BR0114734A (es)
CA (1) CA2425666A1 (es)
CO (1) CO5640115A2 (es)
DE (2) DE10050662A1 (es)
EC (1) ECSP034553A (es)
ES (1) ES2241882T3 (es)
HK (1) HK1057551A1 (es)
HU (1) HUP0302464A2 (es)
IL (2) IL155380A0 (es)
MX (1) MXPA03003198A (es)
NO (1) NO20031412L (es)
NZ (1) NZ525652A (es)
PE (1) PE20020435A1 (es)
PL (1) PL361915A1 (es)
PT (1) PT1326866E (es)
RU (1) RU2003113966A (es)
SK (1) SK4142003A3 (es)
WO (1) WO2002030933A1 (es)
ZA (1) ZA200303640B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10310106A1 (de) * 2003-03-06 2004-09-16 Grünenthal GmbH Substituierte Pyridot [1,2-a]pyrimidin-Verbindungen
US20070155738A1 (en) 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
AU2009330234A1 (en) * 2008-12-22 2011-07-07 Merck Sharp & Dohme Corp. Gamma secretase modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178910B (en) * 1977-08-19 1982-07-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines
US4666912A (en) * 1984-11-12 1987-05-19 Chinoin Gyogyszer Es Vegyeszeti Termeker Gyara Rt Treating process

Also Published As

Publication number Publication date
HK1057551A1 (en) 2004-04-08
SK4142003A3 (en) 2003-10-07
ZA200303640B (en) 2004-08-12
KR20030036924A (ko) 2003-05-09
AU2002210526B2 (en) 2006-10-19
PE20020435A1 (es) 2002-05-18
NZ525652A (en) 2005-01-28
US7230103B2 (en) 2007-06-12
JP4315678B2 (ja) 2009-08-19
CA2425666A1 (en) 2003-04-11
ATE297927T1 (de) 2005-07-15
CO5640115A2 (es) 2006-05-31
RU2003113966A (ru) 2004-12-10
CN1255407C (zh) 2006-05-10
HUP0302464A2 (hu) 2003-11-28
PT1326866E (pt) 2005-08-31
JP2004511484A (ja) 2004-04-15
EP1326866A1 (de) 2003-07-16
EP1326866B1 (de) 2005-06-15
IL155380A (en) 2009-02-11
BR0114734A (pt) 2003-07-01
NO20031412L (no) 2003-04-22
DE10050662A1 (de) 2002-04-18
ES2241882T3 (es) 2005-11-01
WO2002030933A1 (de) 2002-04-18
CN1479740A (zh) 2004-03-03
NO20031412D0 (no) 2003-03-27
ECSP034553A (es) 2003-05-26
DE50106542D1 (de) 2005-07-21
PL361915A1 (en) 2004-10-04
AR034266A1 (es) 2004-02-18
AU1052602A (en) 2002-04-22
IL155380A0 (en) 2003-11-23
US20030229104A1 (en) 2003-12-11

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