BRPI0406748A - Método de tratamento de náusea, vÈmito e ânsia de vÈmito ou qualquer combinação destes em um paciente que necessite do mesmo e composição farmacêutica - Google Patents

Método de tratamento de náusea, vÈmito e ânsia de vÈmito ou qualquer combinação destes em um paciente que necessite do mesmo e composição farmacêutica

Info

Publication number
BRPI0406748A
BRPI0406748A BR0406748-7A BRPI0406748A BRPI0406748A BR PI0406748 A BRPI0406748 A BR PI0406748A BR PI0406748 A BRPI0406748 A BR PI0406748A BR PI0406748 A BRPI0406748 A BR PI0406748A
Authority
BR
Brazil
Prior art keywords
vomiting
patient
craving
combination
need
Prior art date
Application number
BR0406748-7A
Other languages
English (en)
Inventor
Steven B Landau
Cheryl L Miller
Karl Bruce Thor
Original Assignee
Dynogen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dynogen Pharmaceuticals Inc filed Critical Dynogen Pharmaceuticals Inc
Publication of BRPI0406748A publication Critical patent/BRPI0406748A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Dental Preparations (AREA)

Abstract

"MéTODO DE TRATAMENTO DE NáUSEA, VÈMITO E âNSIA DE VÈMITO OU QUALQUER COMBINAçãO DESTES EM UM PACIENTE QUE NECESSITE DO MESMO E COMPOSIçãO FARMACêUTICA". A invenção refere-se a um método de tratamento de náusea, vómito e ânsia de vómito ou qualquer combinação destes em um paciente que necessite do tratamento. O método compreende a administração, a um paciente que necessite de tratamento, de uma quantidade eficaz, do ponto de vista terapêutico, de um composto que tem atividade antagónica do receptor 5-HT~ 3~ e atividade Inibidor de recaptação de NorAdrenalina (NARI). A invenção se refere, ainda, a um método de tratamento de náusea, vómito e ânsia de vómito ou qualquer combinação destes em um paciente com necessidade do mesmo, compreendendo a co-administração ao dito paciente de uma primeira quantidade de um antagonista de 5-HT~ 3~ e uma segunda quantidade de um NARI, em que a primeira e a segunda quantidades, juntas, compreendem uma quantidade eficaz do ponto de vista terapêutico ou estão presentes, cada uma, em uma quantidade eficaz do ponto de vista terapêutico. Além disso, o método da invenção compreende a administração de NARI sozinho.
BR0406748-7A 2003-01-13 2004-01-13 Método de tratamento de náusea, vÈmito e ânsia de vÈmito ou qualquer combinação destes em um paciente que necessite do mesmo e composição farmacêutica BRPI0406748A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44007603P 2003-01-13 2003-01-13
US49247803P 2003-08-04 2003-08-04
PCT/US2004/000809 WO2004062624A2 (en) 2003-01-13 2004-01-13 Method of treating nausea, vomiting, retching or any combination thereof

Publications (1)

Publication Number Publication Date
BRPI0406748A true BRPI0406748A (pt) 2005-12-20

Family

ID=32718144

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0406748-7A BRPI0406748A (pt) 2003-01-13 2004-01-13 Método de tratamento de náusea, vÈmito e ânsia de vÈmito ou qualquer combinação destes em um paciente que necessite do mesmo e composição farmacêutica

Country Status (14)

Country Link
US (3) US20040147510A1 (pt)
EP (1) EP1567163B1 (pt)
JP (1) JP2006516977A (pt)
KR (1) KR20050094843A (pt)
AT (1) ATE359079T1 (pt)
AU (1) AU2004204827B2 (pt)
BR (1) BRPI0406748A (pt)
CA (1) CA2512022A1 (pt)
DE (1) DE602004005814T2 (pt)
ES (1) ES2285407T3 (pt)
MX (1) MXPA05007379A (pt)
NZ (1) NZ541009A (pt)
PL (1) PL378369A1 (pt)
WO (1) WO2004062624A2 (pt)

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Also Published As

Publication number Publication date
KR20050094843A (ko) 2005-09-28
WO2004062624A3 (en) 2005-04-07
ATE359079T1 (de) 2007-05-15
WO2004062624A2 (en) 2004-07-29
PL378369A1 (pl) 2006-04-03
US20040147510A1 (en) 2004-07-29
CA2512022A1 (en) 2004-07-29
MXPA05007379A (es) 2006-02-10
AU2004204827A1 (en) 2004-07-29
AU2004204827B2 (en) 2006-06-29
EP1567163A4 (en) 2006-01-18
ES2285407T3 (es) 2007-11-16
US20040254172A1 (en) 2004-12-16
EP1567163A2 (en) 2005-08-31
JP2006516977A (ja) 2006-07-13
NZ541009A (en) 2007-09-28
DE602004005814D1 (de) 2007-05-24
DE602004005814T2 (de) 2008-01-10
US7094786B2 (en) 2006-08-22
EP1567163B1 (en) 2007-04-11
US20040254171A1 (en) 2004-12-16

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