ATE414081T1 - Bizyklische heteroaromatische verbindungen als kinase hemmstoffe - Google Patents
Bizyklische heteroaromatische verbindungen als kinase hemmstoffeInfo
- Publication number
- ATE414081T1 ATE414081T1 AT03753708T AT03753708T ATE414081T1 AT E414081 T1 ATE414081 T1 AT E414081T1 AT 03753708 T AT03753708 T AT 03753708T AT 03753708 T AT03753708 T AT 03753708T AT E414081 T1 ATE414081 T1 AT E414081T1
- Authority
- AT
- Austria
- Prior art keywords
- bizyclic
- kinase inhibitors
- heteroaromatic compounds
- kinase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Obesity (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0222743.7A GB0222743D0 (en) | 2002-10-01 | 2002-10-01 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE414081T1 true ATE414081T1 (de) | 2008-11-15 |
Family
ID=9945093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03753708T ATE414081T1 (de) | 2002-10-01 | 2003-09-30 | Bizyklische heteroaromatische verbindungen als kinase hemmstoffe |
Country Status (10)
Country | Link |
---|---|
US (1) | US7456286B2 (de) |
EP (1) | EP1549648B1 (de) |
JP (1) | JP2006504712A (de) |
AT (1) | ATE414081T1 (de) |
AU (1) | AU2003271870B2 (de) |
CA (1) | CA2500844A1 (de) |
DE (1) | DE60324696D1 (de) |
ES (1) | ES2315527T3 (de) |
GB (1) | GB0222743D0 (de) |
WO (1) | WO2004031188A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0224082D0 (en) | 2002-10-16 | 2002-11-27 | Celltech R&D Ltd | Biological products |
PL1928454T3 (pl) | 2005-05-10 | 2015-03-31 | Intermune Inc | Pochodne pirydonu do modulowania układu kinazy białkowej aktywowanego stresem |
US8258152B2 (en) * | 2007-06-12 | 2012-09-04 | Genentech, Inc. | N-substituted azaindoles and methods of use |
CA3034994A1 (en) | 2008-06-03 | 2009-12-10 | Intermune, Inc. | Substituted aryl-2 pyridone compounds and use thereof for treating inflammatory and fibrotic disorders |
AR072008A1 (es) * | 2008-06-13 | 2010-07-28 | Merck & Co Inc | Compuestos heterobiciclicos como agentes de inhibicion de quinasa p38 |
AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
GB201317363D0 (en) | 2013-10-01 | 2013-11-13 | Eisai Ltd | Novel compounds |
KR102373700B1 (ko) | 2014-04-02 | 2022-03-11 | 인터뮨, 인크. | 항섬유성 피리디논 |
US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
EP3515912B1 (de) | 2016-09-26 | 2020-10-14 | Centre National De La Recherche Scientifique | Verbindungen zur verwendung in der bildgebung, insbesondere zur diagnose von neurodegenerativen erkrankungen |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002517486A (ja) * | 1998-06-12 | 2002-06-18 | バーテックス ファーマシューティカルズ インコーポレイテッド | p38のインヒビター |
GB0124848D0 (en) * | 2001-10-16 | 2001-12-05 | Celltech R&D Ltd | Chemical compounds |
GB0218800D0 (en) * | 2002-08-13 | 2002-09-18 | Celltech R&D Ltd | Chemical compounds |
-
2002
- 2002-10-01 GB GBGB0222743.7A patent/GB0222743D0/en not_active Ceased
-
2003
- 2003-09-30 AT AT03753708T patent/ATE414081T1/de not_active IP Right Cessation
- 2003-09-30 JP JP2004540940A patent/JP2006504712A/ja active Pending
- 2003-09-30 CA CA002500844A patent/CA2500844A1/en not_active Abandoned
- 2003-09-30 EP EP03753708A patent/EP1549648B1/de not_active Expired - Lifetime
- 2003-09-30 US US10/529,413 patent/US7456286B2/en not_active Expired - Fee Related
- 2003-09-30 WO PCT/GB2003/004214 patent/WO2004031188A1/en active Application Filing
- 2003-09-30 ES ES03753708T patent/ES2315527T3/es not_active Expired - Lifetime
- 2003-09-30 AU AU2003271870A patent/AU2003271870B2/en not_active Ceased
- 2003-09-30 DE DE60324696T patent/DE60324696D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1549648A1 (de) | 2005-07-06 |
EP1549648B1 (de) | 2008-11-12 |
CA2500844A1 (en) | 2004-04-15 |
JP2006504712A (ja) | 2006-02-09 |
ES2315527T3 (es) | 2009-04-01 |
AU2003271870B2 (en) | 2009-08-27 |
WO2004031188A1 (en) | 2004-04-15 |
US7456286B2 (en) | 2008-11-25 |
DE60324696D1 (de) | 2008-12-24 |
US20060122212A1 (en) | 2006-06-08 |
AU2003271870A1 (en) | 2004-04-23 |
GB0222743D0 (en) | 2002-11-06 |
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