IL160082A0 - Quinoline derivatives and use thereof as antitumor agents - Google Patents

Quinoline derivatives and use thereof as antitumor agents

Info

Publication number
IL160082A0
IL160082A0 IL16008202A IL16008202A IL160082A0 IL 160082 A0 IL160082 A0 IL 160082A0 IL 16008202 A IL16008202 A IL 16008202A IL 16008202 A IL16008202 A IL 16008202A IL 160082 A0 IL160082 A0 IL 160082A0
Authority
IL
Israel
Prior art keywords
formula
compound
antitumor agents
quinoline derivatives
salt
Prior art date
Application number
IL16008202A
Other languages
English (en)
Original Assignee
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wayne State filed Critical Univ Wayne State
Publication of IL160082A0 publication Critical patent/IL160082A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
IL16008202A 2001-07-31 2002-07-31 Quinoline derivatives and use thereof as antitumor agents IL160082A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30914401P 2001-07-31 2001-07-31
PCT/US2002/024442 WO2003011832A1 (en) 2001-07-31 2002-07-31 Quinoline derivatives and use thereof as antitumor agents

Publications (1)

Publication Number Publication Date
IL160082A0 true IL160082A0 (en) 2004-06-20

Family

ID=23196886

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16008202A IL160082A0 (en) 2001-07-31 2002-07-31 Quinoline derivatives and use thereof as antitumor agents
IL160082A IL160082A (en) 2001-07-31 2004-01-27 Quinoline derivatives, pharmaceutical compositions containing them and their use in the preparation of compositions for treating cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL160082A IL160082A (en) 2001-07-31 2004-01-27 Quinoline derivatives, pharmaceutical compositions containing them and their use in the preparation of compositions for treating cancer

Country Status (22)

Country Link
US (3) US6867219B2 (no)
EP (1) EP1412332B1 (no)
JP (1) JP4310185B2 (no)
KR (1) KR20040055774A (no)
AT (1) ATE287397T1 (no)
AU (1) AU2002355747B2 (no)
CA (1) CA2456173A1 (no)
DE (1) DE60202682T2 (no)
DK (1) DK1412332T3 (no)
EA (1) EA007205B1 (no)
ES (1) ES2236548T3 (no)
GE (1) GEP20063754B (no)
HU (1) HUP0401562A2 (no)
IL (2) IL160082A0 (no)
MX (1) MXPA04000968A (no)
NO (1) NO326463B1 (no)
NZ (1) NZ530806A (no)
PL (1) PL367340A1 (no)
PT (1) PT1412332E (no)
UA (1) UA75691C2 (no)
WO (1) WO2003011832A1 (no)
ZA (1) ZA200401185B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60115394T2 (de) * 2000-02-29 2006-10-19 Millennium Pharmaceuticals, Inc., Cambridge Benzamide und ähnliche inhibitoren vom faktor xa
PL367340A1 (en) * 2001-07-31 2005-02-21 Wayne State University Quinoline derivatives and use thereof as antitumor agents
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
RU2322236C2 (ru) * 2002-08-24 2008-04-20 Центарис Гмбх Лекарственное средство для лечения доброкачественных и злокачественных опухолевых заболеваний, содержащее производное дисоразола
US8183379B2 (en) 2005-09-07 2012-05-22 Wayne State University Antitumor agents
US20070054938A1 (en) * 2005-09-07 2007-03-08 Horwitz Jerome P Antitumor agents
US7470788B2 (en) 2005-09-07 2008-12-30 Wayne State University Antitumor agents
EP1897542A1 (en) * 2006-09-07 2008-03-12 Sanofi-Aventis Aqueous formulation comprising an antitumor agent
JO2685B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
WO2009002955A1 (en) * 2007-06-27 2008-12-31 Sanofi-Aventis U.S. Llc Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid
US8809562B2 (en) 2011-06-06 2014-08-19 Chevron Phillips Chemical Company Lp Use of metallocene compounds for cancer treatment
WO2024132001A1 (en) * 2022-12-21 2024-06-27 Charles University, Faculty Of Pharmacy In Hradec Kralove Multitarget nuclear receptor ligands based on 2-(4-(quinolin-2-yloxy)phenoxy)propanoic acid and 2-(4-(quinoxalin-2-yloxy)phenoxy)propanoic acid for the treatment of metabolic and liver diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6033389B2 (ja) * 1979-02-22 1985-08-02 日産化学工業株式会社 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤
US6197728B1 (en) 1980-08-06 2001-03-06 Nissan Chemical Industries Ltd. Quinoxaline derivatives and herbicidal composition
US5364831A (en) 1980-08-06 1994-11-15 Nissan Chemical Industries Ltd. Quinoxaline derivatives and herbicidal composition
US5250690A (en) * 1985-05-02 1993-10-05 Dowelanco Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides
PL367340A1 (en) * 2001-07-31 2005-02-21 Wayne State University Quinoline derivatives and use thereof as antitumor agents
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
US7470788B2 (en) * 2005-09-07 2008-12-30 Wayne State University Antitumor agents

Also Published As

Publication number Publication date
GEP20063754B (en) 2006-02-27
DE60202682D1 (de) 2005-02-24
ATE287397T1 (de) 2005-02-15
JP4310185B2 (ja) 2009-08-05
US20050159447A1 (en) 2005-07-21
AU2002355747B2 (en) 2007-12-20
NO326463B1 (no) 2008-12-08
US6867219B2 (en) 2005-03-15
PL367340A1 (en) 2005-02-21
US7241894B2 (en) 2007-07-10
EP1412332B1 (en) 2005-01-19
EA007205B1 (ru) 2006-08-25
US20070232643A1 (en) 2007-10-04
HUP0401562A2 (hu) 2004-12-28
NZ530806A (en) 2006-05-26
UA75691C2 (en) 2006-05-15
WO2003011832A1 (en) 2003-02-13
KR20040055774A (ko) 2004-06-26
CA2456173A1 (en) 2003-02-13
JP2004538314A (ja) 2004-12-24
US20030144321A1 (en) 2003-07-31
IL160082A (en) 2009-06-15
DK1412332T3 (da) 2005-05-30
ES2236548T3 (es) 2005-07-16
EP1412332A1 (en) 2004-04-28
MXPA04000968A (es) 2005-02-17
DE60202682T2 (de) 2005-12-29
US7507749B2 (en) 2009-03-24
NO20040382L (no) 2004-03-26
ZA200401185B (en) 2004-10-21
EA200400219A1 (ru) 2004-12-30
PT1412332E (pt) 2005-06-30

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