IL159255A0 - Benzo [g] quinoline derivatives for treating glaucoma and myopia - Google Patents

Benzo [g] quinoline derivatives for treating glaucoma and myopia

Info

Publication number
IL159255A0
IL159255A0 IL15925502A IL15925502A IL159255A0 IL 159255 A0 IL159255 A0 IL 159255A0 IL 15925502 A IL15925502 A IL 15925502A IL 15925502 A IL15925502 A IL 15925502A IL 159255 A0 IL159255 A0 IL 159255A0
Authority
IL
Israel
Prior art keywords
myopia
benzo
quinoline derivatives
treating glaucoma
glaucoma
Prior art date
Application number
IL15925502A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL159255A0 publication Critical patent/IL159255A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL15925502A 2001-07-09 2002-07-08 Benzo [g] quinoline derivatives for treating glaucoma and myopia IL159255A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01116553 2001-07-09
PCT/EP2002/007594 WO2003006458A1 (en) 2001-07-09 2002-07-08 Benzo [g] quinoline derivatives for treating glaucoma and myopia

Publications (1)

Publication Number Publication Date
IL159255A0 true IL159255A0 (en) 2004-06-01

Family

ID=8177978

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15925502A IL159255A0 (en) 2001-07-09 2002-07-08 Benzo [g] quinoline derivatives for treating glaucoma and myopia
IL159255A IL159255A (en) 2001-07-09 2003-12-08 Benzo [g] quinoline derivatives, process for their preparation, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating glaucoma and myopia

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL159255A IL159255A (en) 2001-07-09 2003-12-08 Benzo [g] quinoline derivatives, process for their preparation, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating glaucoma and myopia

Country Status (25)

Country Link
US (1) US7105528B2 (enExample)
EP (1) EP1419149B1 (enExample)
JP (2) JP5006505B2 (enExample)
KR (2) KR101069948B1 (enExample)
CN (1) CN1293071C (enExample)
AR (1) AR036131A1 (enExample)
AT (1) ATE443060T1 (enExample)
AU (1) AU2002328856B2 (enExample)
BR (1) BR0210894A (enExample)
CA (1) CA2452920C (enExample)
DE (1) DE60233740D1 (enExample)
EC (1) ECSP024377A (enExample)
ES (1) ES2330732T3 (enExample)
HU (1) HUP0400833A3 (enExample)
IL (2) IL159255A0 (enExample)
MX (1) MXPA03012039A (enExample)
MY (1) MY130656A (enExample)
NO (1) NO327549B1 (enExample)
NZ (1) NZ530314A (enExample)
PE (1) PE20030240A1 (enExample)
PL (1) PL208284B1 (enExample)
PT (1) PT1419149E (enExample)
RU (1) RU2300532C2 (enExample)
WO (1) WO2003006458A1 (enExample)
ZA (1) ZA200309642B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG24415A (en) * 2002-03-07 2009-05-25 Novartis Ag Quinoline derivatives
CA2536874A1 (en) * 2003-09-05 2005-03-17 Novartis Ag Compositions comprising benzo (g) quinoline derivatives and prostaglandin derivatives
RU2438670C1 (ru) * 2010-12-24 2012-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО "РостГМУ" Минздравсоцразвития России) Способ лечения ишемического варианта первичной открытоугольной глаукомы у лиц с миопической рефракцией
AR113908A1 (es) 2017-11-24 2020-06-24 H Lundbeck As Profármacos de catecolamina para uso en el tratamiento de la enfermedad de parkinson
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
JP7696829B2 (ja) 2019-05-21 2025-06-23 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するためのカテコールアミンカルバメートプロドラッグ
US12384765B2 (en) 2019-05-21 2025-08-12 H. Lundbeck A/S Catecholamine prodrugs for use in the treatment of Parkinson's Disease
WO2020234275A1 (en) 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's diseases
WO2020234276A1 (en) 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4114325A1 (de) 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
US5262422A (en) * 1991-05-02 1993-11-16 Sandoz Ltd. Octahydrobenzo[g]quinoline
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW357143B (en) * 1995-07-07 1999-05-01 Novartis Ag Benzo[g]quinoline derivatives
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them

Also Published As

Publication number Publication date
CA2452920C (en) 2010-03-30
KR20100007983A (ko) 2010-01-22
PT1419149E (pt) 2009-11-25
NO327549B1 (no) 2009-08-10
JP2010024243A (ja) 2010-02-04
NO20040059L (no) 2004-01-07
KR20040013126A (ko) 2004-02-11
CA2452920A1 (en) 2003-01-23
CN1525969A (zh) 2004-09-01
NZ530314A (en) 2005-08-26
MXPA03012039A (es) 2004-03-26
AR036131A1 (es) 2004-08-11
RU2004102398A (ru) 2005-07-10
EP1419149A1 (en) 2004-05-19
PE20030240A1 (es) 2003-04-16
ES2330732T3 (es) 2009-12-15
US20040171628A1 (en) 2004-09-02
HUP0400833A2 (hu) 2004-07-28
ATE443060T1 (de) 2009-10-15
PL365254A1 (en) 2004-12-27
JP5006505B2 (ja) 2012-08-22
DE60233740D1 (de) 2009-10-29
IL159255A (en) 2010-05-17
PL208284B1 (pl) 2011-04-29
BR0210894A (pt) 2004-06-22
ZA200309642B (en) 2004-10-04
KR101069948B1 (ko) 2011-10-04
US7105528B2 (en) 2006-09-12
EP1419149B1 (en) 2009-09-16
ECSP024377A (es) 2004-08-27
WO2003006458A1 (en) 2003-01-23
AU2002328856B2 (en) 2005-08-04
JP2004538278A (ja) 2004-12-24
MY130656A (en) 2007-07-31
HUP0400833A3 (en) 2010-03-29
RU2300532C2 (ru) 2007-06-10
CN1293071C (zh) 2007-01-03
HK1066211A1 (en) 2005-03-18

Similar Documents

Publication Publication Date Title
AU5393400A (en) Device for treating glaucoma of the eye
AU2001219185A1 (en) 2-acylaminobenzimidazole derivatives for treating glaucoma
HUP0201111A3 (en) Shunt device for treating glaucoma
AU2001245522A1 (en) Apparatus and method for treating glaucoma
EP1441743A4 (en) METHODS FOR TREATING NEOFORMATIONS OF OCULAR BLOOD VESSELS
ZA200409501B (en) [1,4]Diazepino[6,7,1,-ij]quinoline derivatives as antipsychotic and antiobesity agents
AU3998400A (en) Methods of treating c1s-mediated diseases and conditions, and compounds and compositions therefor
IL144517A0 (en) Compositions and methods for treating cataracts
HUP0004747A3 (en) 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinoline derivatives and process for their preparation
PL358481A1 (en) 6-hydroxy-indazole derivatives for treating glaucoma
IL159255A0 (en) Benzo [g] quinoline derivatives for treating glaucoma and myopia
AU2002307430A1 (en) Method and system for photodisruption of tissue of the eye
AU5601300A (en) Method and compositions for treating and preventing retinal damage
AU2042301A (en) 1-aminoalkyl-1H-indoles for treating glaucoma
ZA200003768B (en) Methods and compositions for treating diseases and conditions of the eye.
AU2001237939A1 (en) Methods for treating glaucoma
PL358296A1 (en) 5ht2 agonists for controlling iop and treating glaucoma
AU2002241670A1 (en) Method for treating glaucoma IB
AU4511201A (en) Compositions and methods for the induction and treatment of retinal detachments
AU4026501A (en) Prolate shaped corneal reshaping
MXPA03005855A (es) Metodo para preparacion regioselectiva de benzo[g]quinolin-3-carbonitrilos sustituidos y benzo[g]quinazolinas sustituidas.
AU2080201A (en) Treatment of addiction disorders
IL152782A0 (en) S-methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders
ZA200302911B (en) Method and composition for treatment of ocular hypertension and glaucoma.
AU4114301A (en) Treatment of ocular hypertension and glaucoma