ZA200309642B - Benzo (G) quinoline derivatives for treating glaucoma and myopia. - Google Patents
Benzo (G) quinoline derivatives for treating glaucoma and myopia.Info
- Publication number
- ZA200309642B ZA200309642B ZA200309642A ZA200309642A ZA200309642B ZA 200309642 B ZA200309642 B ZA 200309642B ZA 200309642 A ZA200309642 A ZA 200309642A ZA 200309642 A ZA200309642 A ZA 200309642A ZA 200309642 B ZA200309642 B ZA 200309642B
- Authority
- ZA
- South Africa
- Prior art keywords
- myopia
- benzo
- quinoline derivatives
- treating glaucoma
- glaucoma
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title 1
- RFQDDXWZZVRLKO-UHFFFAOYSA-N benzo[g]quinoline Chemical class N1=CC=CC2=CC3=CC=CC=C3C=C21 RFQDDXWZZVRLKO-UHFFFAOYSA-N 0.000 title 1
- 208000001491 myopia Diseases 0.000 title 1
- 230000004379 myopia Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01116553 | 2001-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200309642B true ZA200309642B (en) | 2004-10-04 |
Family
ID=8177978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200309642A ZA200309642B (en) | 2001-07-09 | 2003-12-11 | Benzo (G) quinoline derivatives for treating glaucoma and myopia. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7105528B2 (enExample) |
| EP (1) | EP1419149B1 (enExample) |
| JP (2) | JP5006505B2 (enExample) |
| KR (2) | KR101069948B1 (enExample) |
| CN (1) | CN1293071C (enExample) |
| AR (1) | AR036131A1 (enExample) |
| AT (1) | ATE443060T1 (enExample) |
| AU (1) | AU2002328856B2 (enExample) |
| BR (1) | BR0210894A (enExample) |
| CA (1) | CA2452920C (enExample) |
| DE (1) | DE60233740D1 (enExample) |
| EC (1) | ECSP024377A (enExample) |
| ES (1) | ES2330732T3 (enExample) |
| HU (1) | HUP0400833A3 (enExample) |
| IL (2) | IL159255A0 (enExample) |
| MX (1) | MXPA03012039A (enExample) |
| MY (1) | MY130656A (enExample) |
| NO (1) | NO327549B1 (enExample) |
| NZ (1) | NZ530314A (enExample) |
| PE (1) | PE20030240A1 (enExample) |
| PL (1) | PL208284B1 (enExample) |
| PT (1) | PT1419149E (enExample) |
| RU (1) | RU2300532C2 (enExample) |
| WO (1) | WO2003006458A1 (enExample) |
| ZA (1) | ZA200309642B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EG24415A (en) * | 2002-03-07 | 2009-05-25 | Novartis Ag | Quinoline derivatives |
| JP2007504198A (ja) * | 2003-09-05 | 2007-03-01 | ノバルティス アクチエンゲゼルシャフト | ベンゾ［ｇ］キノリン誘導体とプロスタグランジン誘導体を含む、組成物 |
| RU2438670C1 (ru) * | 2010-12-24 | 2012-01-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО "РостГМУ" Минздравсоцразвития России) | Способ лечения ишемического варианта первичной открытоугольной глаукомы у лиц с миопической рефракцией |
| PT3713933T (pt) | 2017-11-24 | 2026-05-19 | H Lundbeck As | Novos profrmacos de catecolamina para utilizao no tratamento de doena de parkinson |
| US11104697B2 (en) | 2019-05-20 | 2021-08-31 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
| US11130775B2 (en) | 2019-05-20 | 2021-09-28 | H. Lundbeck A/S | Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
| US11168056B2 (en) | 2019-05-20 | 2021-11-09 | H. Lundbeck A/S | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol |
| US11111263B2 (en) | 2019-05-20 | 2021-09-07 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
| EP3972600B1 (en) | 2019-05-21 | 2026-02-18 | H. Lundbeck A/S | Catecholamine carbamate prodrugs for use in the treatment of parkinson s disease |
| JP7641234B2 (ja) | 2019-05-21 | 2025-03-06 | ハー・ルンドベック・アクチエゼルスカベット | パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ |
| US12391650B2 (en) | 2019-05-21 | 2025-08-19 | H. Lundbeck A/S | Catecholamine prodrugs for use in the treatment of Parkinson's disease |
| WO2020234275A1 (en) | 2019-05-21 | 2020-11-26 | H. Lundbeck A/S | New catecholamine prodrugs for use in the treatment of parkinson's diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262422A (en) * | 1991-05-02 | 1993-11-16 | Sandoz Ltd. | Octahydrobenzo[g]quinoline |
| DE4114325A1 (de) * | 1991-05-02 | 1992-11-05 | Sandoz Ag | Octahydrobenzo(g)chinolin, seine herstellung und verwendung |
| GB9326010D0 (en) | 1993-12-21 | 1994-02-23 | Sandoz Ltd | Improvements in or relating to organic compounds |
| TW357143B (en) * | 1995-07-07 | 1999-05-01 | Novartis Ag | Benzo[g]quinoline derivatives |
| TW378209B (en) * | 1996-07-08 | 2000-01-01 | Novartis Ag | Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them |
-
2002
- 2002-07-03 PE PE2002000598A patent/PE20030240A1/es not_active Application Discontinuation
- 2002-07-05 AR ARP020102532A patent/AR036131A1/es active IP Right Grant
- 2002-07-08 NZ NZ530314A patent/NZ530314A/en not_active IP Right Cessation
- 2002-07-08 KR KR1020047000232A patent/KR101069948B1/ko not_active Expired - Fee Related
- 2002-07-08 RU RU2004102398/04A patent/RU2300532C2/ru not_active IP Right Cessation
- 2002-07-08 PL PL365254A patent/PL208284B1/pl not_active IP Right Cessation
- 2002-07-08 CN CNB028138619A patent/CN1293071C/zh not_active Expired - Fee Related
- 2002-07-08 AU AU2002328856A patent/AU2002328856B2/en not_active Ceased
- 2002-07-08 AT AT02764648T patent/ATE443060T1/de active
- 2002-07-08 US US10/483,310 patent/US7105528B2/en not_active Expired - Fee Related
- 2002-07-08 MY MYPI20022579A patent/MY130656A/en unknown
- 2002-07-08 MX MXPA03012039A patent/MXPA03012039A/es active IP Right Grant
- 2002-07-08 ES ES02764648T patent/ES2330732T3/es not_active Expired - Lifetime
- 2002-07-08 KR KR1020097025779A patent/KR20100007983A/ko not_active Ceased
- 2002-07-08 JP JP2003512230A patent/JP5006505B2/ja not_active Expired - Fee Related
- 2002-07-08 EP EP02764648A patent/EP1419149B1/en not_active Expired - Lifetime
- 2002-07-08 BR BR0210894-1A patent/BR0210894A/pt not_active Application Discontinuation
- 2002-07-08 PT PT02764648T patent/PT1419149E/pt unknown
- 2002-07-08 WO PCT/EP2002/007594 patent/WO2003006458A1/en not_active Ceased
- 2002-07-08 CA CA2452920A patent/CA2452920C/en not_active Expired - Fee Related
- 2002-07-08 IL IL15925502A patent/IL159255A0/xx unknown
- 2002-07-08 HU HU0400833A patent/HUP0400833A3/hu unknown
- 2002-07-08 DE DE60233740T patent/DE60233740D1/de not_active Expired - Lifetime
- 2002-12-11 EC EC2002004377A patent/ECSP024377A/es unknown
-
2003
- 2003-12-08 IL IL159255A patent/IL159255A/en not_active IP Right Cessation
- 2003-12-11 ZA ZA200309642A patent/ZA200309642B/xx unknown
-
2004
- 2004-01-07 NO NO20040059A patent/NO327549B1/no not_active IP Right Cessation
-
2009
- 2009-10-30 JP JP2009250333A patent/JP2010024243A/ja not_active Withdrawn
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