ZA200309642B - Benzo (G) quinoline derivatives for treating glaucoma and myopia. - Google Patents

Benzo (G) quinoline derivatives for treating glaucoma and myopia.

Info

Publication number
ZA200309642B
ZA200309642B ZA200309642A ZA200309642A ZA200309642B ZA 200309642 B ZA200309642 B ZA 200309642B ZA 200309642 A ZA200309642 A ZA 200309642A ZA 200309642 A ZA200309642 A ZA 200309642A ZA 200309642 B ZA200309642 B ZA 200309642B
Authority
ZA
South Africa
Prior art keywords
myopia
benzo
quinoline derivatives
treating glaucoma
glaucoma
Prior art date
Application number
ZA200309642A
Other languages
English (en)
Inventor
Rudolf Markstein
Peter Gull
Esteban Pombo Villar
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200309642B publication Critical patent/ZA200309642B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200309642A 2001-07-09 2003-12-11 Benzo (G) quinoline derivatives for treating glaucoma and myopia. ZA200309642B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01116553 2001-07-09

Publications (1)

Publication Number Publication Date
ZA200309642B true ZA200309642B (en) 2004-10-04

Family

ID=8177978

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200309642A ZA200309642B (en) 2001-07-09 2003-12-11 Benzo (G) quinoline derivatives for treating glaucoma and myopia.

Country Status (25)

Country Link
US (1) US7105528B2 (enExample)
EP (1) EP1419149B1 (enExample)
JP (2) JP5006505B2 (enExample)
KR (2) KR101069948B1 (enExample)
CN (1) CN1293071C (enExample)
AR (1) AR036131A1 (enExample)
AT (1) ATE443060T1 (enExample)
AU (1) AU2002328856B2 (enExample)
BR (1) BR0210894A (enExample)
CA (1) CA2452920C (enExample)
DE (1) DE60233740D1 (enExample)
EC (1) ECSP024377A (enExample)
ES (1) ES2330732T3 (enExample)
HU (1) HUP0400833A3 (enExample)
IL (2) IL159255A0 (enExample)
MX (1) MXPA03012039A (enExample)
MY (1) MY130656A (enExample)
NO (1) NO327549B1 (enExample)
NZ (1) NZ530314A (enExample)
PE (1) PE20030240A1 (enExample)
PL (1) PL208284B1 (enExample)
PT (1) PT1419149E (enExample)
RU (1) RU2300532C2 (enExample)
WO (1) WO2003006458A1 (enExample)
ZA (1) ZA200309642B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG24415A (en) * 2002-03-07 2009-05-25 Novartis Ag Quinoline derivatives
CA2536874A1 (en) * 2003-09-05 2005-03-17 Novartis Ag Compositions comprising benzo (g) quinoline derivatives and prostaglandin derivatives
RU2438670C1 (ru) * 2010-12-24 2012-01-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО "РостГМУ" Минздравсоцразвития России) Способ лечения ишемического варианта первичной открытоугольной глаукомы у лиц с миопической рефракцией
AR113908A1 (es) 2017-11-24 2020-06-24 H Lundbeck As Profármacos de catecolamina para uso en el tratamiento de la enfermedad de parkinson
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
JP7696829B2 (ja) 2019-05-21 2025-06-23 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するためのカテコールアミンカルバメートプロドラッグ
US12384765B2 (en) 2019-05-21 2025-08-12 H. Lundbeck A/S Catecholamine prodrugs for use in the treatment of Parkinson's Disease
WO2020234275A1 (en) 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's diseases
WO2020234276A1 (en) 2019-05-21 2020-11-26 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4114325A1 (de) 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
US5262422A (en) * 1991-05-02 1993-11-16 Sandoz Ltd. Octahydrobenzo[g]quinoline
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW357143B (en) * 1995-07-07 1999-05-01 Novartis Ag Benzo[g]quinoline derivatives
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them

Also Published As

Publication number Publication date
CA2452920C (en) 2010-03-30
KR20100007983A (ko) 2010-01-22
PT1419149E (pt) 2009-11-25
NO327549B1 (no) 2009-08-10
JP2010024243A (ja) 2010-02-04
NO20040059L (no) 2004-01-07
IL159255A0 (en) 2004-06-01
KR20040013126A (ko) 2004-02-11
CA2452920A1 (en) 2003-01-23
CN1525969A (zh) 2004-09-01
NZ530314A (en) 2005-08-26
MXPA03012039A (es) 2004-03-26
AR036131A1 (es) 2004-08-11
RU2004102398A (ru) 2005-07-10
EP1419149A1 (en) 2004-05-19
PE20030240A1 (es) 2003-04-16
ES2330732T3 (es) 2009-12-15
US20040171628A1 (en) 2004-09-02
HUP0400833A2 (hu) 2004-07-28
ATE443060T1 (de) 2009-10-15
PL365254A1 (en) 2004-12-27
JP5006505B2 (ja) 2012-08-22
DE60233740D1 (de) 2009-10-29
IL159255A (en) 2010-05-17
PL208284B1 (pl) 2011-04-29
BR0210894A (pt) 2004-06-22
KR101069948B1 (ko) 2011-10-04
US7105528B2 (en) 2006-09-12
EP1419149B1 (en) 2009-09-16
ECSP024377A (es) 2004-08-27
WO2003006458A1 (en) 2003-01-23
AU2002328856B2 (en) 2005-08-04
JP2004538278A (ja) 2004-12-24
MY130656A (en) 2007-07-31
HUP0400833A3 (en) 2010-03-29
RU2300532C2 (ru) 2007-06-10
CN1293071C (zh) 2007-01-03
HK1066211A1 (en) 2005-03-18

Similar Documents

Publication Publication Date Title
AU2001219185A1 (en) 2-acylaminobenzimidazole derivatives for treating glaucoma
AU5393400A (en) Device for treating glaucoma of the eye
AU2001228759A1 (en) Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols
HUP0201111A3 (en) Shunt device for treating glaucoma
AU2002305278A1 (en) Bifurcatable trabecular shunt for glaucoma treatment
AU2001245522A1 (en) Apparatus and method for treating glaucoma
GC0000155A (en) 6-Hydroxy-indazole derivatives for treating glaucoma.
AU3467300A (en) Method for treating glaucoma, device for realising the same and variants
ZA200107689B (en) 1-Arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives for the treatment of CNS disorders.
ZA200309642B (en) Benzo (G) quinoline derivatives for treating glaucoma and myopia.
AU2042301A (en) 1-aminoalkyl-1H-indoles for treating glaucoma
AU2001237939A1 (en) Methods for treating glaucoma
MXPA03003741A (es) Metodos y composiciones para el tratamiento de enfermedades oftalmicas.
ZA200205098B (en) Dihydrobenzopyrans, dihydrobenzothiopyrans, and tetrahydroquinolines for the treatment of cox-2-mediated disorders.
PL358296A1 (en) 5ht2 agonists for controlling iop and treating glaucoma
ZA994105B (en) Method for treating glaucoma.
WO2004028451A3 (en) β-HYDROXYPHENYLALKYLAMINES AND THEIR USE FOR TREATING GLAUCOMA
AU4026501A (en) Prolate shaped corneal reshaping
ZA200203435B (en) Method and compositions for treating pulmonary diseases.
WO2005058911A3 (en) Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
AU2002322747A1 (en) Adaptive ablation centering for pupil dilation effects
ZA200302911B (en) Method and composition for treatment of ocular hypertension and glaucoma.
WO2001085152A3 (en) R-eliprodil for treating glaucoma
HK1050196A (en) 6-hydroxy-indazole derivatives for treating glaucoma
HK1051979A (en) Methods for treating glaucoma