PL358481A1 - 6-hydroxy-indazole derivatives for treating glaucoma - Google Patents
6-hydroxy-indazole derivatives for treating glaucomaInfo
- Publication number
- PL358481A1 PL358481A1 PL00358481A PL35848100A PL358481A1 PL 358481 A1 PL358481 A1 PL 358481A1 PL 00358481 A PL00358481 A PL 00358481A PL 35848100 A PL35848100 A PL 35848100A PL 358481 A1 PL358481 A1 PL 358481A1
- Authority
- PL
- Poland
- Prior art keywords
- hydroxy
- treating glaucoma
- indazole derivatives
- indazole
- derivatives
- Prior art date
Links
- NUYZVDBIVNOTSC-UHFFFAOYSA-N 1H-indazol-6-ol Chemical class OC1=CC=C2C=NNC2=C1 NUYZVDBIVNOTSC-UHFFFAOYSA-N 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19038000P | 2000-03-17 | 2000-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL358481A1 true PL358481A1 (en) | 2004-08-09 |
Family
ID=22701093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL00358481A PL358481A1 (en) | 2000-03-17 | 2000-11-14 | 6-hydroxy-indazole derivatives for treating glaucoma |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1268438A1 (en) |
| JP (1) | JP2003528085A (en) |
| KR (1) | KR20030065304A (en) |
| CN (1) | CN1450994A (en) |
| AR (1) | AR032138A1 (en) |
| AU (1) | AU2001216072A1 (en) |
| BR (1) | BR0017157A (en) |
| CA (1) | CA2402403A1 (en) |
| GC (1) | GC0000155A (en) |
| MX (1) | MXPA02008547A (en) |
| PL (1) | PL358481A1 (en) |
| TW (1) | TWI221839B (en) |
| WO (1) | WO2001070702A1 (en) |
| ZA (1) | ZA200206851B (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960579B1 (en) | 1998-05-19 | 2005-11-01 | Alcon Manufacturing, Ltd. | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders |
| TW593302B (en) | 2001-12-20 | 2004-06-21 | Alcon Inc | Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma |
| AU2002360819A1 (en) * | 2001-12-28 | 2003-07-24 | Bayer Corporation | Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor |
| US7196082B2 (en) | 2002-11-08 | 2007-03-27 | Merck & Co. Inc. | Ophthalmic compositions for treating ocular hypertension |
| EP1581503A4 (en) | 2002-11-08 | 2007-07-25 | Merck & Co Inc | OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION |
| CN100384827C (en) * | 2002-11-08 | 2008-04-30 | 默克公司 | Ophthalmic composition for the treatment of ocular hypertension |
| US7053085B2 (en) | 2003-03-26 | 2006-05-30 | Merck & Co. Inc. | EP4 receptor agonist, compositions and methods thereof |
| WO2004054572A2 (en) | 2002-12-13 | 2004-07-01 | Alcon, Inc. | Novel benzopyran analogs and their use for the treatment of glaucoma |
| JP2004262812A (en) * | 2003-02-28 | 2004-09-24 | Rohto Pharmaceut Co Ltd | Ocular hypotensive |
| EP1664011A4 (en) | 2003-09-02 | 2009-02-25 | Merck & Co Inc | OPHTHALMIC COMPOSITIONS FOR THE TREATMENT OF OCULAR HYPERTENSION |
| WO2005025568A1 (en) | 2003-09-04 | 2005-03-24 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
| AU2004272546B2 (en) | 2003-09-04 | 2007-10-18 | Merck Sharp & Dohme Corp. | Ophthalmic compositions for treating ocular hypertension |
| US7338972B1 (en) | 2003-12-15 | 2008-03-04 | Alcon, Inc. | Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma |
| US6989445B2 (en) | 2003-12-15 | 2006-01-24 | Alcon, Inc. | Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma |
| US7129257B1 (en) | 2003-12-15 | 2006-10-31 | Alcon, Inc. | Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma |
| CA2574078A1 (en) | 2004-07-20 | 2006-02-23 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
| CN101111494A (en) | 2004-11-29 | 2008-01-23 | 沃纳-兰伯特有限公司 | Therapeutic pyrazolo[3,4-b]pyridines and indazoles |
| WO2006062839A1 (en) | 2004-12-08 | 2006-06-15 | Alcon, Inc. | Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma |
| CN101704785B (en) * | 2009-11-16 | 2012-02-29 | 东南大学 | Organic dicarboxylic acid and salts thereof and preparation method thereof |
| CN105884687B (en) * | 2016-04-14 | 2018-06-22 | 梯尔希（南京）药物研发有限公司 | A kind of preparation method of 5- benzyls benzydamine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999059499A2 (en) * | 1998-05-19 | 1999-11-25 | Alcon Laboratories, Inc. | Serotonergic 5ht7 receptor compounds for treating ocular and cns disorders |
| ATE247963T1 (en) * | 1998-05-26 | 2003-09-15 | Pfizer Prod Inc | DRUG FOR TREATING GLAUCOMA AND ISCHEMIC RETINOPATHY |
| GB9819032D0 (en) * | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds IV |
| EP1112106B1 (en) * | 1998-09-18 | 2005-11-23 | Alcon Manufacturing Ltd. | Serotonergic 5ht2 agonists for treating glaucoma |
| GB9820767D0 (en) * | 1998-09-23 | 1998-11-18 | Cerebrus Ltd | Chemical compounds VIII |
-
2000
- 2000-11-14 PL PL00358481A patent/PL358481A1/en not_active Application Discontinuation
- 2000-11-14 JP JP2001568912A patent/JP2003528085A/en not_active Withdrawn
- 2000-11-14 BR BR0017157-3A patent/BR0017157A/en not_active IP Right Cessation
- 2000-11-14 CA CA002402403A patent/CA2402403A1/en not_active Abandoned
- 2000-11-14 MX MXPA02008547A patent/MXPA02008547A/en unknown
- 2000-11-14 WO PCT/US2000/031247 patent/WO2001070702A1/en not_active Ceased
- 2000-11-14 AU AU2001216072A patent/AU2001216072A1/en not_active Abandoned
- 2000-11-14 CN CN00819346A patent/CN1450994A/en active Pending
- 2000-11-14 KR KR1020027011867A patent/KR20030065304A/en not_active Ceased
- 2000-11-14 EP EP00978628A patent/EP1268438A1/en not_active Withdrawn
- 2000-11-27 TW TW089125127A patent/TWI221839B/en not_active IP Right Cessation
- 2000-12-01 AR ARP000106394A patent/AR032138A1/en not_active Application Discontinuation
- 2000-12-03 GC GCP20001082 patent/GC0000155A/en active
-
2002
- 2002-08-27 ZA ZA200206851A patent/ZA200206851B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1450994A (en) | 2003-10-22 |
| TWI221839B (en) | 2004-10-11 |
| AR032138A1 (en) | 2003-10-29 |
| ZA200206851B (en) | 2003-10-21 |
| AU2001216072A1 (en) | 2001-10-03 |
| MXPA02008547A (en) | 2003-03-12 |
| BR0017157A (en) | 2002-11-26 |
| WO2001070702A1 (en) | 2001-09-27 |
| EP1268438A1 (en) | 2003-01-02 |
| CA2402403A1 (en) | 2001-09-27 |
| KR20030065304A (en) | 2003-08-06 |
| GC0000155A (en) | 2005-06-29 |
| JP2003528085A (en) | 2003-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |