BR0017157A - 6-hydroxy-indazole derivatives for the treatment of glaucoma - Google Patents
6-hydroxy-indazole derivatives for the treatment of glaucomaInfo
- Publication number
- BR0017157A BR0017157A BR0017157-3A BR0017157A BR0017157A BR 0017157 A BR0017157 A BR 0017157A BR 0017157 A BR0017157 A BR 0017157A BR 0017157 A BR0017157 A BR 0017157A
- Authority
- BR
- Brazil
- Prior art keywords
- glaucoma
- hydroxy
- treatment
- indazole derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"DERIVADOS DE 6-HIDRóXI-INDAZOL PARA O TRATAMENTO DE GLAUCOMA". São divulgados 1-(<244>-alquil-etilamino)-1H-indazol-6-óis substituídos, úteis para diminuir e controlar a IOP e tratar o glaucoma."6-HYDROXY-INDAZOL DERIVATIVES FOR THE TREATMENT OF GLAUCOMA". Substituted 1- (<244> -alkyl-ethylamino) -1H-indazol-6-ools are disclosed, useful for decreasing and controlling IOP and treating glaucoma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19038000P | 2000-03-17 | 2000-03-17 | |
PCT/US2000/031247 WO2001070702A1 (en) | 2000-03-17 | 2000-11-14 | 6-hydroxy-indazole derivatives for treating glaucoma |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0017157A true BR0017157A (en) | 2002-11-26 |
Family
ID=22701093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0017157-3A BR0017157A (en) | 2000-03-17 | 2000-11-14 | 6-hydroxy-indazole derivatives for the treatment of glaucoma |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1268438A1 (en) |
JP (1) | JP2003528085A (en) |
KR (1) | KR20030065304A (en) |
CN (1) | CN1450994A (en) |
AR (1) | AR032138A1 (en) |
AU (1) | AU2001216072A1 (en) |
BR (1) | BR0017157A (en) |
CA (1) | CA2402403A1 (en) |
GC (1) | GC0000155A (en) |
MX (1) | MXPA02008547A (en) |
PL (1) | PL358481A1 (en) |
TW (1) | TWI221839B (en) |
WO (1) | WO2001070702A1 (en) |
ZA (1) | ZA200206851B (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6960579B1 (en) | 1998-05-19 | 2005-11-01 | Alcon Manufacturing, Ltd. | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders |
TW593302B (en) | 2001-12-20 | 2004-06-21 | Alcon Inc | Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma |
WO2003057213A2 (en) * | 2001-12-28 | 2003-07-17 | Bayer Pharmaceuticals Corporation | Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor |
CN100384827C (en) * | 2002-11-08 | 2008-04-30 | 默克公司 | Ophthalmic compositions for treating ocular hypertension |
JP2006510742A (en) | 2002-11-08 | 2006-03-30 | メルク エンド カムパニー インコーポレーテッド | Ophthalmic composition for high intraocular pressure treatment |
US7196082B2 (en) | 2002-11-08 | 2007-03-27 | Merck & Co. Inc. | Ophthalmic compositions for treating ocular hypertension |
US7053085B2 (en) | 2003-03-26 | 2006-05-30 | Merck & Co. Inc. | EP4 receptor agonist, compositions and methods thereof |
CA2506204A1 (en) | 2002-12-13 | 2004-07-01 | Alcon, Inc. | Novel benzopyran analogs and their use for the treatment of glaucoma |
JP2004262812A (en) * | 2003-02-28 | 2004-09-24 | Rohto Pharmaceut Co Ltd | Hypotonia bulbi medicine |
JP2007504228A (en) | 2003-09-02 | 2007-03-01 | メルク エンド カムパニー インコーポレーテッド | Ophthalmic composition for treating ocular hypertension |
WO2005026128A1 (en) | 2003-09-04 | 2005-03-24 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
EP1663221A4 (en) | 2003-09-04 | 2009-04-22 | Merck & Co Inc | Ophthalmic compositions for treating ocular hypertension |
WO2005058911A2 (en) | 2003-12-15 | 2005-06-30 | Alcon, Inc. | Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma |
US7129257B1 (en) | 2003-12-15 | 2006-10-31 | Alcon, Inc. | Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma |
US7338972B1 (en) | 2003-12-15 | 2008-03-04 | Alcon, Inc. | Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma |
JP2008507521A (en) | 2004-07-20 | 2008-03-13 | メルク エンド カムパニー インコーポレーテッド | Ophthalmic composition for treating ocular hypertension |
BRPI0518693A2 (en) | 2004-11-29 | 2008-12-02 | Warner Lambert Co | pyrazol [3,4-b] pyridines and therapeutic indoles as well as pharmaceutical composition and use thereof |
US7425572B2 (en) | 2004-12-08 | 2008-09-16 | Alcon, Inc. | Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma |
CN101704785B (en) * | 2009-11-16 | 2012-02-29 | 东南大学 | Organic dicarboxylic acid and salts thereof and preparation method thereof |
CN105884687B (en) * | 2016-04-14 | 2018-06-22 | 梯尔希(南京)药物研发有限公司 | A kind of preparation method of 5- benzyls benzydamine |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002515408A (en) * | 1998-05-19 | 2002-05-28 | アルコン ラボラトリーズ, インコーポレーテッド | Serotonergic 5HT7 receptor compounds for the treatment of ocular and central nervous system disorders |
EP0985414B1 (en) * | 1998-05-26 | 2003-08-27 | Pfizer Products Inc. | Medicament for the treatment of glaucoma and ischemic retinopathy |
GB9819032D0 (en) * | 1998-09-01 | 1998-10-28 | Cerebrus Ltd | Chemical compounds IV |
JP2002526443A (en) * | 1998-09-18 | 2002-08-20 | アルコン ラボラトリーズ, インコーポレーテッド | Serotoninergic 5HT2 agonist for treating glaucoma |
GB9820767D0 (en) * | 1998-09-23 | 1998-11-18 | Cerebrus Ltd | Chemical compounds VIII |
-
2000
- 2000-11-14 AU AU2001216072A patent/AU2001216072A1/en not_active Abandoned
- 2000-11-14 EP EP00978628A patent/EP1268438A1/en not_active Withdrawn
- 2000-11-14 JP JP2001568912A patent/JP2003528085A/en not_active Withdrawn
- 2000-11-14 PL PL00358481A patent/PL358481A1/en not_active Application Discontinuation
- 2000-11-14 WO PCT/US2000/031247 patent/WO2001070702A1/en not_active Application Discontinuation
- 2000-11-14 CA CA002402403A patent/CA2402403A1/en not_active Abandoned
- 2000-11-14 CN CN00819346A patent/CN1450994A/en active Pending
- 2000-11-14 MX MXPA02008547A patent/MXPA02008547A/en unknown
- 2000-11-14 KR KR1020027011867A patent/KR20030065304A/en not_active Application Discontinuation
- 2000-11-14 BR BR0017157-3A patent/BR0017157A/en not_active IP Right Cessation
- 2000-11-27 TW TW089125127A patent/TWI221839B/en not_active IP Right Cessation
- 2000-12-01 AR ARP000106394A patent/AR032138A1/en not_active Application Discontinuation
- 2000-12-03 GC GCP20001082 patent/GC0000155A/en active
-
2002
- 2002-08-27 ZA ZA200206851A patent/ZA200206851B/en unknown
Also Published As
Publication number | Publication date |
---|---|
MXPA02008547A (en) | 2003-03-12 |
KR20030065304A (en) | 2003-08-06 |
PL358481A1 (en) | 2004-08-09 |
EP1268438A1 (en) | 2003-01-02 |
CN1450994A (en) | 2003-10-22 |
ZA200206851B (en) | 2003-10-21 |
CA2402403A1 (en) | 2001-09-27 |
GC0000155A (en) | 2005-06-29 |
WO2001070702A1 (en) | 2001-09-27 |
JP2003528085A (en) | 2003-09-24 |
AU2001216072A1 (en) | 2001-10-03 |
TWI221839B (en) | 2004-10-11 |
AR032138A1 (en) | 2003-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1962 DE 12/08/2008. |