IL152173A0 - Haemostatically active preparation containing vwf and method for the production thereof - Google Patents

Haemostatically active preparation containing vwf and method for the production thereof

Info

Publication number
IL152173A0
IL152173A0 IL15217301A IL15217301A IL152173A0 IL 152173 A0 IL152173 A0 IL 152173A0 IL 15217301 A IL15217301 A IL 15217301A IL 15217301 A IL15217301 A IL 15217301A IL 152173 A0 IL152173 A0 IL 152173A0
Authority
IL
Israel
Prior art keywords
vwf
fraction
active
production
preparation containing
Prior art date
Application number
IL15217301A
Other languages
English (en)
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of IL152173A0 publication Critical patent/IL152173A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL15217301A 2000-04-18 2001-04-04 Haemostatically active preparation containing vwf and method for the production thereof IL152173A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00108430A EP1148063A1 (de) 2000-04-18 2000-04-18 Haemostatisch aktives vWF enthaltendes Präparat und Verfahren zu seiner Herstellung
PCT/EP2001/003819 WO2001079260A1 (de) 2000-04-18 2001-04-04 Haemostatisch aktives vwf enthaltendes präparat und verfahren zu seiner herstellung

Publications (1)

Publication Number Publication Date
IL152173A0 true IL152173A0 (en) 2003-05-29

Family

ID=8168496

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15217301A IL152173A0 (en) 2000-04-18 2001-04-04 Haemostatically active preparation containing vwf and method for the production thereof
IL152173A IL152173A (en) 2000-04-18 2002-10-08 An active mosquito repellent containing VWF and a method for its preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL152173A IL152173A (en) 2000-04-18 2002-10-08 An active mosquito repellent containing VWF and a method for its preparation

Country Status (24)

Country Link
US (2) US7166709B2 (et)
EP (2) EP1148063A1 (et)
JP (1) JP4976634B2 (et)
KR (1) KR100685448B1 (et)
CN (1) CN100448888C (et)
AT (1) ATE306494T1 (et)
AU (2) AU6383501A (et)
BR (1) BR0110193A (et)
CA (1) CA2406626C (et)
CZ (1) CZ303932B6 (et)
DE (1) DE50107689D1 (et)
DK (1) DK1274721T3 (et)
EA (1) EA006209B1 (et)
EE (1) EE200200595A (et)
ES (1) ES2247117T3 (et)
HU (1) HU225992B1 (et)
IL (2) IL152173A0 (et)
MX (1) MXPA02010017A (et)
NO (1) NO324773B1 (et)
RS (1) RS50835B (et)
SI (1) SI1274721T1 (et)
UA (1) UA76714C2 (et)
WO (1) WO2001079260A1 (et)
ZA (1) ZA200208396B (et)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1148063A1 (de) * 2000-04-18 2001-10-24 Octapharma AG Haemostatisch aktives vWF enthaltendes Präparat und Verfahren zu seiner Herstellung
ITLU20070007A1 (it) * 2007-05-07 2008-11-08 Kedrion Spa Processo cromatografico per l'ottenimento di un complesso fviii/vwf con differenti rapporti tra le due proteine da utilizzare nella terapia della emofilia a e nella malattia di von willebrand.
FR2920429B1 (fr) * 2007-08-30 2012-10-05 Lfb Biotechnologies Procede de purification du facteur viii et du facteur von willebrand
CN101952016A (zh) 2007-12-28 2011-01-19 巴克斯特国际公司 重组vwf配方
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
CN103739712B (zh) 2008-06-24 2016-10-05 德国杰特贝林生物制品有限公司 具有延长的体内半衰期的因子viii、冯·维勒布兰德因子或它们的复合物
AU2009307648C1 (en) 2008-10-21 2016-12-08 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
IT1396528B1 (it) * 2009-01-19 2012-12-14 Kedrion Spa Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn).
MX344402B (es) * 2010-06-01 2016-12-14 Baxter Int Inc * Proceso para elaborar composiciones hemostaticas secas y estables.
RU2603103C2 (ru) * 2010-09-20 2016-11-20 Октафарма Аг Способ получения фибриногена с использованием сильной анионообменной смолы и содержащий фибриноген продукт
EP2652491B1 (en) 2010-12-15 2017-11-29 Baxalta GmbH Eluate collection using conductivity gradient
US10064406B2 (en) * 2011-01-06 2018-09-04 Cytosorbents Corporation Polymeric sorbent for removal of impurities from whole blood and blood products
EP2825555B1 (en) 2012-03-13 2017-07-12 Octapharma AG Mproved process for production of fibrinogen and fibrinogen produced thereby
EP2841451A1 (en) 2012-04-24 2015-03-04 Novo Nordisk A/S Compounds suitable for treatment of haemophilia
EP2796145B1 (en) 2013-04-22 2017-11-01 CSL Ltd. A covalent complex of von willebrand factor and faktor viii linked by a disulphide bridge

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT389815B (de) * 1984-03-09 1990-02-12 Immuno Ag Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten
FR2632309B1 (fr) 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
ATE85221T1 (de) 1988-11-05 1993-02-15 Octapharma Ag Verfahren zur herstellung eines hochreinen, nicht infektioesen antihaemophiliefaktors mittels chromatographie.
FR2673632A1 (fr) * 1991-03-08 1992-09-11 Lille Transfusion Sanguine Procede de preparation de concentre de facteur von willebrand humain de tres haute purete, approprie a un usage therapeutique.
FR2681867B1 (fr) * 1991-09-26 1993-12-31 Pasteur Merieux Serums Vaccins Procede de purification du facteur viii et preparations obtenues.
DE4204694C3 (de) * 1992-02-01 1995-10-12 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem Faktor VIII mittels Anionenaustauscher-Chromatographie
WO1994013329A1 (de) * 1992-12-16 1994-06-23 Immuno Aktiengesellschaft Verfahren zur herstellung eines virussicheren biologischen präparates
DE4435392B4 (de) * 1994-10-04 2008-02-07 Immuno Ag Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF
DE4437544A1 (de) * 1994-10-20 1996-04-25 Behringwerke Ag Einsatz von vWF-enthaltenden Konzentraten als Kombinationstherapie bei Therapie mit Antithrombotika und Fibrinolytika
US6005077A (en) * 1995-11-10 1999-12-21 Immuno Aktiengesellschaft Use of von willebrand factor and pharmaceutical formulation
AT403764B (de) * 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
AT404358B (de) * 1997-02-04 1998-11-25 Immuno Ag Verfahren zur chromatographischen reinigung bzw. fraktionierung von von willebrand-faktor aus einem vwf-hältigen ausgangsmaterial
US6531577B1 (en) * 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
EP1148063A1 (de) * 2000-04-18 2001-10-24 Octapharma AG Haemostatisch aktives vWF enthaltendes Präparat und Verfahren zu seiner Herstellung

Also Published As

Publication number Publication date
ATE306494T1 (de) 2005-10-15
EP1274721B1 (de) 2005-10-12
WO2001079260A1 (de) 2001-10-25
PL358388A1 (en) 2004-08-09
DK1274721T3 (da) 2006-02-13
US20070232791A1 (en) 2007-10-04
CZ303932B6 (cs) 2013-07-03
CZ20023454A3 (cs) 2003-05-14
KR100685448B1 (ko) 2007-02-23
YU78402A (sh) 2006-08-17
KR20030019352A (ko) 2003-03-06
RS50835B (sr) 2010-08-31
CA2406626C (en) 2012-02-21
HUP0301211A3 (en) 2005-12-28
JP4976634B2 (ja) 2012-07-18
UA76714C2 (uk) 2006-09-15
HUP0301211A2 (hu) 2003-07-28
US7166709B2 (en) 2007-01-23
CN1425024A (zh) 2003-06-18
EE200200595A (et) 2004-04-15
AU6383501A (en) 2001-10-30
US7985846B2 (en) 2011-07-26
US20030138913A1 (en) 2003-07-24
MXPA02010017A (es) 2003-04-25
NO20025007D0 (no) 2002-10-17
NO20025007L (no) 2002-11-28
EA006209B1 (ru) 2005-10-27
EA200201104A1 (ru) 2003-04-24
EP1274721A1 (de) 2003-01-15
NO324773B1 (no) 2007-12-10
IL152173A (en) 2007-07-24
EP1148063A1 (de) 2001-10-24
AU2001263835B2 (en) 2005-06-09
JP2004516231A (ja) 2004-06-03
CA2406626A1 (en) 2001-10-25
HU225992B1 (en) 2008-02-28
ES2247117T3 (es) 2006-03-01
SI1274721T1 (sl) 2006-04-30
ZA200208396B (en) 2004-04-30
BR0110193A (pt) 2003-02-11
DE50107689D1 (de) 2006-02-23
CN100448888C (zh) 2009-01-07

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