IL152073A0 - Percyquinnin, a process for its production and its use as a pharmaceutical - Google Patents

Percyquinnin, a process for its production and its use as a pharmaceutical

Info

Publication number
IL152073A0
IL152073A0 IL15207301A IL15207301A IL152073A0 IL 152073 A0 IL152073 A0 IL 152073A0 IL 15207301 A IL15207301 A IL 15207301A IL 15207301 A IL15207301 A IL 15207301A IL 152073 A0 IL152073 A0 IL 152073A0
Authority
IL
Israel
Prior art keywords
percyquinnin
production
pharmaceutically acceptable
pharmaceutical
dsm
Prior art date
Application number
IL15207301A
Other languages
English (en)
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of IL152073A0 publication Critical patent/IL152073A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
IL15207301A 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical IL152073A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00107536A EP1142886A1 (en) 2000-04-07 2000-04-07 Percyquinnin, a process for its production and its use as a pharmaceutical
PCT/EP2001/003392 WO2001077094A1 (en) 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical

Publications (1)

Publication Number Publication Date
IL152073A0 true IL152073A0 (en) 2003-05-29

Family

ID=8168397

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15207301A IL152073A0 (en) 2000-04-07 2001-03-24 Percyquinnin, a process for its production and its use as a pharmaceutical
IL152073A IL152073A (en) 2000-04-07 2002-10-02 Persiquin, a process for its preparation, and its use as a pharmaceutical

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL152073A IL152073A (en) 2000-04-07 2002-10-02 Persiquin, a process for its preparation, and its use as a pharmaceutical

Country Status (30)

Country Link
US (1) US6596518B2 (ru)
EP (2) EP1142886A1 (ru)
JP (1) JP2003530391A (ru)
KR (1) KR100791798B1 (ru)
CN (1) CN1199959C (ru)
AT (1) ATE269855T1 (ru)
AU (2) AU784902B2 (ru)
BR (1) BR0109854A (ru)
CA (1) CA2405066A1 (ru)
CZ (1) CZ20023310A3 (ru)
DE (1) DE60103995T2 (ru)
DK (1) DK1274698T3 (ru)
EE (1) EE200200572A (ru)
ES (1) ES2222992T3 (ru)
HK (1) HK1052005A1 (ru)
HR (1) HRP20020796A2 (ru)
HU (1) HUP0300327A3 (ru)
IL (2) IL152073A0 (ru)
MX (1) MXPA02007895A (ru)
NO (1) NO20024772D0 (ru)
NZ (1) NZ521782A (ru)
PL (1) PL357909A1 (ru)
PT (1) PT1274698E (ru)
RS (1) RS50140B (ru)
RU (1) RU2266290C2 (ru)
SI (1) SI1274698T1 (ru)
SK (1) SK14322002A3 (ru)
TR (1) TR200401739T4 (ru)
WO (1) WO2001077094A1 (ru)
ZA (1) ZA200207910B (ru)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1142886A1 (en) * 2000-04-07 2001-10-10 Aventis Pharma Deutschland GmbH Percyquinnin, a process for its production and its use as a pharmaceutical
US7105526B2 (en) 2002-06-28 2006-09-12 Banyu Pharmaceuticals Co., Ltd. Benzimidazole derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
AU2004274309B2 (en) 2003-09-22 2010-04-08 Msd K.K. Novel piperidine derivative
EP1734963A4 (en) 2004-04-02 2008-06-18 Merck & Co Inc METHOD FOR TREATING PEOPLE WITH METABOLIC AND ANTHROPOMETRIC DISORDER
US7572783B2 (en) 2004-08-13 2009-08-11 Amgen Inc. Substituted benzofused heterocycles
CA2618112A1 (en) 2005-08-10 2007-02-15 Banyu Pharmaceutical Co., Ltd. Pyridone compound
CA2619770A1 (en) 2005-08-24 2007-03-01 Banyu Pharmaceutical Co., Ltd. Phenylpyridone derivative
AU2006288153A1 (en) 2005-09-07 2007-03-15 Msd K.K. Bicyclic aromatic substituted pyridone derivative
US8293900B2 (en) 2005-09-29 2012-10-23 Merck Sharp & Dohme Corp Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
AU2006304836A1 (en) 2005-10-21 2007-04-26 Novartis Ag Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
CA2627139A1 (en) 2005-10-27 2007-05-03 Banyu Pharmaceutical Co., Ltd. Novel benzoxathiin derivative
JP4371164B2 (ja) 2005-11-10 2009-11-25 萬有製薬株式会社 アザ置換スピロ誘導体
CN100417650C (zh) * 2006-08-17 2008-09-10 中国科学院昆明植物研究所 韧革菌素及其制备方法和在药物上的应用
AU2007300627B2 (en) 2006-09-22 2012-02-16 Merck Sharp & Dohme Corp. Method of treatment using fatty acid synthesis inhibitors
JPWO2008038692A1 (ja) 2006-09-28 2010-01-28 萬有製薬株式会社 ジアリールケチミン誘導体
CA2682727C (en) 2007-04-02 2016-03-22 Banyu Pharmaceutical Co., Ltd. Indoledione derivative
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20110015181A1 (en) 2008-03-06 2011-01-20 Makoto Ando Alkylaminopyridine derivative
US20110015198A1 (en) 2008-03-28 2011-01-20 Banyu Pharmaceutical Co., Inc. Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
JPWO2009154132A1 (ja) 2008-06-19 2011-12-01 Ｍｓｄ株式会社 スピロジアミン−ジアリールケトオキシム誘導体
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US20110124674A1 (en) 2008-07-30 2011-05-26 Hiroyuki Kishino 5/5-or 5/6-membered condensed ring cycloalkylamine derivative
EP2348857B1 (en) 2008-10-22 2016-02-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
JP5635991B2 (ja) 2008-10-30 2014-12-03 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． イソニコチンアミドオレキシン受容体アンタゴニスト
CA2741672A1 (en) 2008-10-31 2010-05-06 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
JP2013520502A (ja) 2010-02-25 2013-06-06 メルク・シャープ・エンド・ドーム・コーポレイション 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
MX348131B (es) 2011-02-25 2017-05-26 Merck Sharp & Dohme Novedosos derivados de azabencimidazol ciclico utiles como agentes antidiabeticos.
AR088352A1 (es) 2011-10-19 2014-05-28 Merck Sharp & Dohme Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
MX2015001500A (es) 2012-08-02 2015-04-08 Merck Sharp & Dohme Compuestos antidiabeticos triciclicos.
AU2014219020A1 (en) 2013-02-22 2015-07-23 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
US9650375B2 (en) 2013-03-14 2017-05-16 Merck Sharp & Dohme Corp. Indole derivatives useful as anti-diabetic agents
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
RS65632B1 (sr) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe
WO2015051496A1 (en) 2013-10-08 2015-04-16 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
CA2959208C (en) 2014-08-29 2023-09-19 Tes Pharma S.R.L. Pyrimidine derivatives and their use as inhibitors of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
CN105906500B (zh) * 2016-04-22 2018-06-26 中国科学院昆明植物研究所 具有脂肪酶抑制作用的绵马次酸类化合物及其应用
TWI767945B (zh) 2016-10-14 2022-06-21 義大利商Ｔｅｓ製藥（股份）責任有限公司 α-胺基-β-羧基己二烯二酸半醛去羧酶之抑制劑
EP3551176A4 (en) 2016-12-06 2020-06-24 Merck Sharp & Dohme Corp. ANTIDIABETIC HETEROCYCLIC COMPOUNDS
US10968232B2 (en) 2016-12-20 2021-04-06 Merck Sharp & Dohme Corp. Antidiabetic spirochroman compounds
CN109055231B (zh) * 2018-07-26 2021-04-27 云南大学 一种真菌发酵液及其应用
SG11202104550WA (en) 2018-11-20 2021-05-28 Tes Pharma S R L INHIBITORS OF a-AMINO-ß-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE
TW202045476A (zh) 2019-02-13 2020-12-16 美商默沙東藥廠 5-烷基吡咯啶食慾素受體促效劑
US20230018413A1 (en) 2019-08-08 2023-01-19 Merck Sharp & Dohme Corp. Heteroaryl pyrrolidine and piperidine orexin receptor agonists
CN116249697A (zh) 2020-08-18 2023-06-09 默沙东有限责任公司 二环庚烷吡咯烷食欲素受体激动剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2344285A1 (fr) * 1976-03-19 1977-10-14 Roussel Uclaf Nouvelles lactones derivees du cyclopentanol, leur procede de preparation et leur application comme medicaments
US5322779A (en) * 1992-04-16 1994-06-21 The Research And Development Institute, Inc. At Montana State University Taxol production by taxomyces andreanae
EP1142886A1 (en) * 2000-04-07 2001-10-10 Aventis Pharma Deutschland GmbH Percyquinnin, a process for its production and its use as a pharmaceutical

Also Published As

Publication number Publication date
HRP20020796A2 (en) 2004-12-31
ZA200207910B (en) 2003-07-21
DE60103995D1 (de) 2004-07-29
NZ521782A (en) 2004-05-28
HK1052005A1 (en) 2003-08-29
RS50140B (sr) 2009-03-25
DE60103995T2 (de) 2005-01-05
MXPA02007895A (es) 2002-11-29
AU2006203704B2 (en) 2008-06-26
ES2222992T3 (es) 2005-02-16
HUP0300327A3 (en) 2004-10-28
CZ20023310A3 (cs) 2003-01-15
EE200200572A (et) 2004-04-15
EP1142886A1 (en) 2001-10-10
ATE269855T1 (de) 2004-07-15
EP1274698A1 (en) 2003-01-15
PT1274698E (pt) 2004-10-29
SI1274698T1 (en) 2004-12-31
KR20020084299A (ko) 2002-11-04
NO20024772L (no) 2002-10-03
CA2405066A1 (en) 2001-10-18
AU2006203704B8 (en) 2008-07-10
RU2002129890A (ru) 2004-03-27
US6596518B2 (en) 2003-07-22
DK1274698T3 (da) 2004-11-01
SK14322002A3 (sk) 2003-05-02
NO20024772D0 (no) 2002-10-03
YU74002A (sh) 2005-11-28
HUP0300327A2 (hu) 2003-06-28
JP2003530391A (ja) 2003-10-14
EP1274698B1 (en) 2004-06-23
IL152073A (en) 2007-12-03
AU2006203704A1 (en) 2006-09-21
US20020039768A1 (en) 2002-04-04
TR200401739T4 (tr) 2004-08-23
CN1199959C (zh) 2005-05-04
PL357909A1 (en) 2004-08-09
BR0109854A (pt) 2003-06-03
RU2266290C2 (ru) 2005-12-20
CN1418203A (zh) 2003-05-14
WO2001077094A1 (en) 2001-10-18
AU5621901A (en) 2001-10-23
AU784902B2 (en) 2006-07-20
KR100791798B1 (ko) 2008-01-04

Similar Documents

Publication Publication Date Title
IL152073A0 (en) Percyquinnin, a process for its production and its use as a pharmaceutical
WO2001028996A3 (en) Pyrrolidine derivatives, their preparation and their use as inhibitors of neuraminidases
AP2002002637A0 (en) Novel piperazine
DE69831868D1 (en) Antithrombosemittel
BR9905981A (pt) Compostos isocromano e processos para a sua produção.
JO2646B1 (en) New differentiated cyclic compounds as beta - lactam inhibitors
MXPA02007942A (es) Derivados de pirrolopirimidinona, procesos de preparacion y uso.
MXPA03011954A (es) Nuevos derivados de acido sulfonico.
MY135218A (en) 2,6-quinolinyl and 2,6-naphthyl derivatives and their use in the treatment of vla-4 dependent diseases
GEP20074045B (en) (4-phenyl) piperidin-3-yl-phenylcarboxylate derivatives and related compounds as beta-secretase inhibitors for the treatment of alzheimer's disease
MXPA02012889A (es) Esteres de acidos 4-alcoxi-ciclohexano-1-amino-carboxilicos y procedimiento para su obtencion.
DE60114640D1 (en) Antithrombosemittel
UA70974C2 (ru) Ванкорезмицин (варианты), штамм amycolatopsis вида hil-006734, dsm 12216, который его продуцирует, и фармацевтическая композиция, которая имеет антибиотическую активность
YU81502A (sh) Ciklopostini, postupak za njihovu proizvodnju i njihova primena
WO2002046152A3 (de) Coniosetin und derivate davon, verfahren zur herstellung und verwendung derselben
HUP0102370A2 (hu) Mumbaisztatin, eljárás előállítására és alkalmazása gyógyszerhatóanyagként
BG108151A (en) Caloporoside derivatives, methods for the production thereof and their use
EP1306368A3 (en) 3,4-dihydro-1H-naphtalene derivatives as a highly selective cyclooxygenase-2 inhibitor
MXPA04004537A (es) Derivados de gabusectina, metodo para produccion de los mismos y uso de los mismos.
WO2003029495A3 (de) Coniosulfide und deren derivate, verfahren zur ihrer herstellung und verwendung als arzneimittel
EP1465886A4 (en) BIPYRIDINYL DERIVATIVES AS HIGHLY SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2
MXPA04006358A (es) Derivados del drechsleranol, procedimiento para su preparacion y su utilizacion.
HUT68015A (en) New compound leustroducsin h, its preparation and pharmaceutical compositions containing them
AU2003281344A1 (en) Polyene carboxylic acid derivatives, method for their production and the use thereof
SI1237866T1 (en) Amycomycin, a process for its production and its use as a pharmaceutical

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed