IL149306A0 - Benzamidine derivatives and pharmaceutical compositions containing the same - Google Patents

Benzamidine derivatives and pharmaceutical compositions containing the same

Info

Publication number
IL149306A0
IL149306A0 IL14930600A IL14930600A IL149306A0 IL 149306 A0 IL149306 A0 IL 149306A0 IL 14930600 A IL14930600 A IL 14930600A IL 14930600 A IL14930600 A IL 14930600A IL 149306 A0 IL149306 A0 IL 149306A0
Authority
IL
Israel
Prior art keywords
group
optionally substituted
hydrogen atom
alkyl group
halogen atom
Prior art date
Application number
IL14930600A
Other languages
English (en)
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of IL149306A0 publication Critical patent/IL149306A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Manufacture Of Alloys Or Alloy Compounds (AREA)
IL14930600A 1999-10-28 2000-10-25 Benzamidine derivatives and pharmaceutical compositions containing the same IL149306A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30719299 1999-10-28
PCT/JP2000/007469 WO2001030756A1 (fr) 1999-10-28 2000-10-25 Derives de benzamidine

Publications (1)

Publication Number Publication Date
IL149306A0 true IL149306A0 (en) 2002-11-10

Family

ID=17966162

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14930600A IL149306A0 (en) 1999-10-28 2000-10-25 Benzamidine derivatives and pharmaceutical compositions containing the same
IL149306A IL149306A (en) 1999-10-28 2002-04-23 History of benzamidine and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL149306A IL149306A (en) 1999-10-28 2002-04-23 History of benzamidine and pharmaceutical preparations containing them

Country Status (26)

Country Link
US (3) US6555556B1 (ja)
EP (1) EP1245564B1 (ja)
KR (1) KR100642953B1 (ja)
CN (2) CN1293052C (ja)
AT (1) ATE322479T1 (ja)
AU (1) AU776193B2 (ja)
BR (1) BR0015120A (ja)
CA (1) CA2389156C (ja)
CY (1) CY1106116T1 (ja)
CZ (1) CZ20021432A3 (ja)
DE (1) DE60027204T2 (ja)
DK (1) DK1245564T3 (ja)
ES (1) ES2261248T3 (ja)
HK (1) HK1047431B (ja)
HU (1) HUP0203161A3 (ja)
IL (2) IL149306A0 (ja)
MX (1) MXPA02004218A (ja)
NO (1) NO323147B1 (ja)
NZ (1) NZ518581A (ja)
PL (1) PL354619A1 (ja)
PT (1) PT1245564E (ja)
RU (1) RU2222529C2 (ja)
TR (1) TR200201654T2 (ja)
TW (1) TWI226886B (ja)
WO (1) WO2001030756A1 (ja)
ZA (1) ZA200203278B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU776193B2 (en) * 1999-10-28 2004-09-02 Sankyo Company Limited Benzamidine derivatives
AU2002246336B2 (en) 2001-04-05 2005-05-19 Sankyo Company, Limited Benzamidine derivative
WO2002089803A1 (en) * 2001-05-07 2002-11-14 Sankyo Company, Limited Composition for iontophoresis
CA2479062A1 (en) 2002-03-15 2003-09-25 Kissei Pharmaceutical Co., Ltd. Novel crystals of 5-hydroxycarbamimidoyl-2-hydroxybenzenesulfonamide derivative
WO2006057507A1 (en) * 2004-11-23 2006-06-01 Dong Wha Pharm.Ind.Co., Ltd An oral preparation having improved bioavailability
CN103159620A (zh) * 2013-03-28 2013-06-19 广西师范大学 一种2-羟基间苯二甲酸的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
ZA951617B (en) * 1994-03-04 1997-02-27 Lilly Co Eli Antithrombotic agents.
ES2193202T3 (es) 1994-12-02 2003-11-01 Yamanouchi Pharma Co Ltd Nuevo derivado de amidinonaftilo o sal de este.
RO117913B1 (ro) * 1996-01-02 2002-09-30 Aventis Pharmaceuticals Inc. Derivaţi de n-[(amino-(imino)metil)fenil]propil amide substituite, compoziţie farmaceutică care îi conţine şi metodă de tratament
PT929547E (pt) * 1996-09-12 2003-03-31 Schering Ag Derivados da benzamidina substituidos por derivados de aminoacidos ciclicos e de hidroxiacidos ciclicos e seu uso como anticoagulantes
TW542822B (en) 1997-01-17 2003-07-21 Ajinomoto Kk Benzamidine derivatives
JP2003522733A (ja) * 1999-02-11 2003-07-29 コア セラピューティクス，インコーポレイティド Ｘａ因子の阻害剤としてのアルケニルおよびアルキニル化合物
US6350761B1 (en) * 1999-07-30 2002-02-26 Berlex Laboratories, Inc. Benzenamine derivatives as anti-coagulants
AU776193B2 (en) * 1999-10-28 2004-09-02 Sankyo Company Limited Benzamidine derivatives

Also Published As

Publication number Publication date
CN1572882A (zh) 2005-02-02
CA2389156A1 (en) 2001-05-03
HK1047431A1 (en) 2003-02-21
KR20020092347A (ko) 2002-12-11
DE60027204T2 (de) 2006-11-23
CY1106116T1 (el) 2011-06-08
DE60027204D1 (en) 2006-05-18
EP1245564A4 (en) 2003-03-05
ES2261248T3 (es) 2006-11-16
BR0015120A (pt) 2002-06-25
NO323147B1 (no) 2007-01-08
AU7957400A (en) 2001-05-08
US20040010009A1 (en) 2004-01-15
IL149306A (en) 2007-07-04
NO20021990D0 (no) 2002-04-26
WO2001030756A1 (fr) 2001-05-03
TR200201654T2 (tr) 2002-12-23
CZ20021432A3 (cs) 2002-10-16
EP1245564B1 (en) 2006-04-05
EP1245564A1 (en) 2002-10-02
HUP0203161A2 (hu) 2002-12-28
ZA200203278B (en) 2003-08-26
DK1245564T3 (da) 2006-08-14
CN1293052C (zh) 2007-01-03
NO20021990L (no) 2002-06-25
ATE322479T1 (de) 2006-04-15
HK1047431B (zh) 2006-07-14
PL354619A1 (en) 2004-02-09
CA2389156C (en) 2009-05-12
US6555556B1 (en) 2003-04-29
US20040248981A1 (en) 2004-12-09
AU776193B2 (en) 2004-09-02
TWI226886B (en) 2005-01-21
HUP0203161A3 (en) 2003-12-29
KR100642953B1 (ko) 2006-11-10
NZ518581A (en) 2004-11-26
MXPA02004218A (es) 2002-10-17
RU2222529C2 (ru) 2004-01-27
PT1245564E (pt) 2006-06-30
CN1413189A (zh) 2003-04-23

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed