TR200201654T2 - Benzamidin türevleri. - Google Patents

Benzamidin türevleri.

Info

Publication number
TR200201654T2
TR200201654T2 TR2002/01654T TR200201654T TR200201654T2 TR 200201654 T2 TR200201654 T2 TR 200201654T2 TR 2002/01654 T TR2002/01654 T TR 2002/01654T TR 200201654 T TR200201654 T TR 200201654T TR 200201654 T2 TR200201654 T2 TR 200201654T2
Authority
TR
Turkey
Prior art keywords
relates
treatment
prevention
blood clotting
clotting disorder
Prior art date
Application number
TR2002/01654T
Other languages
English (en)
Inventor
Asai Fumitoshi
Matsuhashi Hayao
Fujimoto Koichi
Original Assignee
Sankyo Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company Limited filed Critical Sankyo Company Limited
Publication of TR200201654T2 publication Critical patent/TR200201654T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Manufacture Of Alloys Or Alloy Compounds (AREA)

Abstract

Bu bulus, faktör Xa'ya karsi üstün inhibitör aktivitesi olan benzamidin türevleriyle ve farmasötik olarak kabul edilebilir tuzlariyla ilgilidir. Bulus ayrica, kan pihtilasmasiyla ilgili bir bozuklugun önlenmesi veya tedavisi için söz konusu bilesimlerin aktif madde olarak içeren farmasötik terkiplerle de ilgilidir. Bulus, ilaveten kan pihtilasmasiyla ilgili bir bozuklugun önlenmesi veya tedavisi için bir ilacin hazirlanmasinda söz konusu bilesimlerin kullanimiyla da ilgilidir. Ayrica bulus, kan pihtilasmasiyla ilgili bir bozuklugun önlenmesi veya tedavisi için, böyle bir tedaviye ihtiyaci olan bir sicak-kanli hayvana söz konusu birlesimlerden farmasötik olarak etkili bir miktarda verilmesini içeren bir yöntemle ilgilidir. Ayrica, bulus söz konusu bilesimlerin hazirlanmasi için bir prosesle de ilgilidir.
TR2002/01654T 1999-10-28 2000-10-25 Benzamidin türevleri. TR200201654T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30719299 1999-10-28

Publications (1)

Publication Number Publication Date
TR200201654T2 true TR200201654T2 (tr) 2002-12-23

Family

ID=17966162

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01654T TR200201654T2 (tr) 1999-10-28 2000-10-25 Benzamidin türevleri.

Country Status (26)

Country Link
US (3) US6555556B1 (tr)
EP (1) EP1245564B1 (tr)
KR (1) KR100642953B1 (tr)
CN (2) CN1293052C (tr)
AT (1) ATE322479T1 (tr)
AU (1) AU776193B2 (tr)
BR (1) BR0015120A (tr)
CA (1) CA2389156C (tr)
CY (1) CY1106116T1 (tr)
CZ (1) CZ20021432A3 (tr)
DE (1) DE60027204T2 (tr)
DK (1) DK1245564T3 (tr)
ES (1) ES2261248T3 (tr)
HK (1) HK1047431B (tr)
HU (1) HUP0203161A3 (tr)
IL (2) IL149306A0 (tr)
MX (1) MXPA02004218A (tr)
NO (1) NO323147B1 (tr)
NZ (1) NZ518581A (tr)
PL (1) PL354619A1 (tr)
PT (1) PT1245564E (tr)
RU (1) RU2222529C2 (tr)
TR (1) TR200201654T2 (tr)
TW (1) TWI226886B (tr)
WO (1) WO2001030756A1 (tr)
ZA (1) ZA200203278B (tr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100642953B1 (ko) * 1999-10-28 2006-11-10 상꾜 가부시키가이샤 벤즈아미딘 유도체
SK12082003A3 (sk) 2001-04-05 2004-09-08 Sankyo Company Limited Benzamidínové deriváty
WO2002089803A1 (en) * 2001-05-07 2002-11-14 Sankyo Company, Limited Composition for iontophoresis
BR0308426A (pt) * 2002-03-15 2005-01-18 Kissei Pharmaceutical Cristais de derivado de 5-hidroxicarbamimidoil-2-hidroxibenzenosulfonami da
EP1701722B1 (en) * 2004-11-23 2009-10-14 Dong Wha Pharmaceutical Co., Ltd. N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxy¨]pentoxy}benzamidine 2 methansulfonic acid salt
CN103159620A (zh) * 2013-03-28 2013-06-19 广西师范大学 一种2-羟基间苯二甲酸的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
ZA951617B (en) * 1994-03-04 1997-02-27 Lilly Co Eli Antithrombotic agents.
TW300888B (tr) 1994-12-02 1997-03-21 Yamanouchi Pharma Co Ltd
EP0906094B1 (en) * 1996-01-02 2003-06-25 Aventis Pharmaceuticals Inc. Substituted n- (aminoiminomethyl or aminomethyl)phenyl]propyl amides
CN1234798A (zh) * 1996-09-12 1999-11-10 舍林股份公司 环状氨基酸和环状羟基羧酸衍生物取代的苄脒衍生物和它们用作抗凝剂的用途
TW542822B (en) 1997-01-17 2003-07-21 Ajinomoto Kk Benzamidine derivatives
EP1159264A2 (en) 1999-02-11 2001-12-05 Cor Therapeutics, Inc. INHIBITORS OF FACTOR Xa
US6350761B1 (en) * 1999-07-30 2002-02-26 Berlex Laboratories, Inc. Benzenamine derivatives as anti-coagulants
KR100642953B1 (ko) * 1999-10-28 2006-11-10 상꾜 가부시키가이샤 벤즈아미딘 유도체

Also Published As

Publication number Publication date
TWI226886B (en) 2005-01-21
EP1245564A4 (en) 2003-03-05
IL149306A (en) 2007-07-04
US20040010009A1 (en) 2004-01-15
CA2389156C (en) 2009-05-12
HK1047431B (zh) 2006-07-14
NO20021990L (no) 2002-06-25
AU7957400A (en) 2001-05-08
CN1572882A (zh) 2005-02-02
CN1413189A (zh) 2003-04-23
US6555556B1 (en) 2003-04-29
HUP0203161A3 (en) 2003-12-29
EP1245564A1 (en) 2002-10-02
AU776193B2 (en) 2004-09-02
DE60027204D1 (en) 2006-05-18
KR20020092347A (ko) 2002-12-11
CY1106116T1 (el) 2011-06-08
HK1047431A1 (en) 2003-02-21
CN1293052C (zh) 2007-01-03
IL149306A0 (en) 2002-11-10
MXPA02004218A (es) 2002-10-17
KR100642953B1 (ko) 2006-11-10
DE60027204T2 (de) 2006-11-23
DK1245564T3 (da) 2006-08-14
PT1245564E (pt) 2006-06-30
ATE322479T1 (de) 2006-04-15
RU2222529C2 (ru) 2004-01-27
NO20021990D0 (no) 2002-04-26
NO323147B1 (no) 2007-01-08
WO2001030756A1 (fr) 2001-05-03
CZ20021432A3 (cs) 2002-10-16
EP1245564B1 (en) 2006-04-05
BR0015120A (pt) 2002-06-25
ES2261248T3 (es) 2006-11-16
US20040248981A1 (en) 2004-12-09
NZ518581A (en) 2004-11-26
PL354619A1 (en) 2004-02-09
ZA200203278B (en) 2003-08-26
CA2389156A1 (en) 2001-05-03
HUP0203161A2 (hu) 2002-12-28

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