MXPA04007183A - Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2. - Google Patents

Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.

Info

Publication number
MXPA04007183A
MXPA04007183A MXPA04007183A MXPA04007183A MXPA04007183A MX PA04007183 A MXPA04007183 A MX PA04007183A MX PA04007183 A MXPA04007183 A MX PA04007183A MX PA04007183 A MXPA04007183 A MX PA04007183A MX PA04007183 A MXPA04007183 A MX PA04007183A
Authority
MX
Mexico
Prior art keywords
diabetes
patients
blood glucose
type
combination
Prior art date
Application number
MXPA04007183A
Other languages
English (en)
Inventor
Jose Manuel Francisco La Ochoa
Original Assignee
Silanes Sa De Cv Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27607097&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA04007183(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Silanes Sa De Cv Lab filed Critical Silanes Sa De Cv Lab
Priority to MXPA04007183A priority Critical patent/MXPA04007183A/es
Priority to BRPI0502691-1A priority patent/BRPI0502691A/pt
Priority to ARP050103077A priority patent/AR050684A1/es
Publication of MXPA04007183A publication Critical patent/MXPA04007183A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

Se aportan composiciones farmaceuticas de las sustancias activas Glimepirida y Metformina o sus sales como clorhidrato, succinato fumarato, etc. para el control de la glucosa en sangre de pacientes con diabetes tipo 2. Para probar la eficacia de la combinacion se realizaron estudios clinicos que probaron que existe un efecto no solo aditivo de los dos farmacos sino sinergetico, en comparacion con la monoterapia empleando solo algunos de los farmacos de la combinacion. En consecuencia se propone el uso de la combinacion como una terapia eficaz y segura para el control de glucosa en sangre de pacientes con diabetes tipo 2 empleando diversas proporciones de las sustancias activas en las combinaciones, para adecuarse a las diferentes necesidades de los pacientes.
MXPA04007183A 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2. MXPA04007183A (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
MXPA04007183A MXPA04007183A (es) 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.
BRPI0502691-1A BRPI0502691A (pt) 2002-01-25 2005-07-08 composição farmacêutica para o controle da glicose no sangue de pacientes com diabetes tipo 2
ARP050103077A AR050684A1 (es) 2004-07-26 2005-07-25 Composicion farmaceutica que comprende metformina o sus sales aceptables para uso farmaceutico con glimepirida y uso de metformina o sus sales aceptables para uso farmaceutico y glimepirida para la manufactura de un medicamento

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXPA04007183A MXPA04007183A (es) 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.
PCT/MX2002/000003 WO2003061643A1 (es) 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2

Publications (1)

Publication Number Publication Date
MXPA04007183A true MXPA04007183A (es) 2006-03-06

Family

ID=27607097

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04007183A MXPA04007183A (es) 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.

Country Status (11)

Country Link
US (2) US9045438B2 (es)
EP (1) EP1482919B1 (es)
AT (1) ATE361065T1 (es)
BR (1) BRPI0502691A (es)
CY (1) CY1106771T1 (es)
DE (1) DE60219963T2 (es)
DK (1) DK1482919T3 (es)
ES (1) ES2284829T3 (es)
MX (1) MXPA04007183A (es)
PT (1) PT1482919E (es)
WO (1) WO2003061643A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04007183A (es) 2002-01-25 2006-03-06 Silanes Sa De Cv Lab Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.
AU2002356419A1 (en) 2002-06-17 2003-12-31 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
FR2896157B1 (fr) * 2006-01-13 2008-09-12 Merck Sante Soc Par Actions Si Combinaison de derives de triazine et d'agents de stimulation de secretion d'insuline.
US20120095059A1 (en) * 2010-04-13 2012-04-19 Jorge Luis Rosado Compositions and Methods for Treating Type II Diabetes and Related Disorders
MX339374B (es) * 2011-04-29 2016-05-13 Inst De Investigación En Química Aplic S A De C V Cocristales ionicos con base en metformina.
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
EP2712628B1 (en) * 2012-09-28 2016-08-10 Shanta Banerjee Composition for use as a medicine or dietetic food, in particular in the prevention and/or treatment of Diabetes and diabetes associated diseases
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
EP3050023B1 (en) 2014-10-27 2021-08-25 Aseko, Inc. Subcutaneous outpatient management
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
AU2016308953B2 (en) 2015-08-20 2020-09-10 Aseko, Inc. Diabetes management therapy advisor

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
US3072527A (en) 1959-07-01 1963-01-08 Horner Frank W Ltd Use of tolbutamide in the treatment of acne
JP3465247B2 (ja) 1992-12-28 2003-11-10 アベンティス ファーマ株式会社 動脈硬化症の予防および治療剤
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US6348469B1 (en) 1995-04-14 2002-02-19 Pharma Pass Llc Solid compositions containing glipizide and polyethylene oxide
IT1276130B1 (it) 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
US6011049A (en) * 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
DE69822505T2 (de) * 1997-12-08 2005-01-20 Bristol-Myers Squibb Co. Neue metformin-salze und verfahren
PT974356E (pt) 1998-07-15 2004-02-27 Merck Sante Sas Comprimidos compreendendo uma combinacao de metformina e de glibenclamida
DE19860698A1 (de) * 1998-12-30 2000-07-06 Hexal Ag Neue pharmazeutische Zusammensetzung
US6559188B1 (en) * 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
US6586438B2 (en) * 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
WO2002011716A2 (en) * 2000-08-07 2002-02-14 Ranbaxy Signature Llc Liquid formulation of metformin
FR2825023B1 (fr) 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
MXPA04007183A (es) 2002-01-25 2006-03-06 Silanes Sa De Cv Lab Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.
US6682759B2 (en) 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
US20030187074A1 (en) 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
EP1562607A1 (en) 2002-11-15 2005-08-17 Ranbaxy Laboratories, Ltd. Pharmaceutical dosage forms of biguanide-sulfonylurea combinations
MXPA05009633A (es) 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.

Also Published As

Publication number Publication date
ATE361065T1 (de) 2007-05-15
DE60219963T2 (de) 2008-02-07
US20050239887A1 (en) 2005-10-27
BRPI0502691A (pt) 2006-03-07
EP1482919B1 (en) 2007-05-02
PT1482919E (pt) 2007-07-25
ES2284829T3 (es) 2007-11-16
DK1482919T3 (da) 2007-07-30
US9045438B2 (en) 2015-06-02
EP1482919A1 (en) 2004-12-08
CY1106771T1 (el) 2012-05-23
DE60219963D1 (de) 2007-06-14
WO2003061643A1 (es) 2003-07-31
US20160051511A1 (en) 2016-02-25

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