CY1106771T1 - Φαρμακευτικη συνθεση η οποια χρησιμοποιειται για τον ελεγχο της γλυκοζης του αιματος σε ασθενεις με διαβητη τυπου 2 - Google Patents

Φαρμακευτικη συνθεση η οποια χρησιμοποιειται για τον ελεγχο της γλυκοζης του αιματος σε ασθενεις με διαβητη τυπου 2

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Publication number
CY1106771T1
CY1106771T1 CY20071101008T CY071101008T CY1106771T1 CY 1106771 T1 CY1106771 T1 CY 1106771T1 CY 20071101008 T CY20071101008 T CY 20071101008T CY 071101008 T CY071101008 T CY 071101008T CY 1106771 T1 CY1106771 T1 CY 1106771T1
Authority
CY
Cyprus
Prior art keywords
patients
diabetes
blood glucose
type
combination
Prior art date
Application number
CY20071101008T
Other languages
English (en)
Inventor
José Manuel Francisco LARA OCHOA
Original Assignee
Laboratorios Silanes, S.A. De C.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27607097&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1106771(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratorios Silanes, S.A. De C.V. filed Critical Laboratorios Silanes, S.A. De C.V.
Publication of CY1106771T1 publication Critical patent/CY1106771T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Φαρμακευτικές συνθέσεις των δραστικών ουσιών γλυμπεπυριδίου με ένζυμο μετασχηματισμού ή τα άλατα αυτής όπως υδροχλωρίδιο, σουκκινικό άλας, φουμαρικό άλας, κλπ είναι χρήσιμες για τον έλεγχο της γλυκόζης του αίματος σε ασθενείς με διαβήτη τύπου 2. Προκειμένου να αποδειχθεί η αποτελεσματικότητα του συνδυασμού, πραγματοποιήθηκαν κλινικές μελέτες οι οποίες κατέδειξαν την ύπαρξη όχι μόνο μιας επιπρόσθετης δράσης, αλλά επίσης μιας συνεργατικής δράσης των δυο φαρμάκων σε σύγκριση με μονοθεραπεία με τη χρησιμοποίηση ενός από τα φάρμακα που χρησιμοποιούνται στο συνδυασμό. Κατά συνέπεια, ο συνδυασμός μπορεί να χρησιμοποιηθεί σαν μια αποτελεσματική και ασφαλής θεραπεία για τον έλεγχο της γλυκόζης του αίματος σε ασθενείς με διαβήτη τύπου 2, με τη χρησιμοποίηση διαφορετικών αναλογιών των δραστικών ουσιών σε συνδυασμούς κατάλληλους για τις ανάγκες των διαφορετικών ασθενών.
CY20071101008T 2002-01-25 2007-07-30 Φαρμακευτικη συνθεση η οποια χρησιμοποιειται για τον ελεγχο της γλυκοζης του αιματος σε ασθενεις με διαβητη τυπου 2 CY1106771T1 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/MX2002/000003 WO2003061643A1 (es) 2002-01-25 2002-01-25 Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2

Publications (1)

Publication Number Publication Date
CY1106771T1 true CY1106771T1 (el) 2012-05-23

Family

ID=27607097

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101008T CY1106771T1 (el) 2002-01-25 2007-07-30 Φαρμακευτικη συνθεση η οποια χρησιμοποιειται για τον ελεγχο της γλυκοζης του αιματος σε ασθενεις με διαβητη τυπου 2

Country Status (11)

Country Link
US (2) US9045438B2 (el)
EP (1) EP1482919B1 (el)
AT (1) ATE361065T1 (el)
BR (1) BRPI0502691A (el)
CY (1) CY1106771T1 (el)
DE (1) DE60219963T2 (el)
DK (1) DK1482919T3 (el)
ES (1) ES2284829T3 (el)
MX (1) MXPA04007183A (el)
PT (1) PT1482919E (el)
WO (1) WO2003061643A1 (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04007183A (es) 2002-01-25 2006-03-06 Silanes Sa De Cv Lab Composicion farmaceutica para el control de la glucosa en sangre de pacientes con diabetes tipo 2.
AU2002356419A1 (en) 2002-06-17 2003-12-31 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
FR2896157B1 (fr) * 2006-01-13 2008-09-12 Merck Sante Soc Par Actions Si Combinaison de derives de triazine et d'agents de stimulation de secretion d'insuline.
BR112012026005A2 (pt) * 2010-04-13 2015-09-08 Nucitec Sa De Cv composições e métodos para tratar diabetes do tipo ii e distúrbios relacionados
MX339374B (es) * 2011-04-29 2016-05-13 Inst De Investigación En Química Aplic S A De C V Cocristales ionicos con base en metformina.
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
EP2712628B1 (en) * 2012-09-28 2016-08-10 Shanta Banerjee Composition for use as a medicine or dietetic food, in particular in the prevention and/or treatment of Diabetes and diabetes associated diseases
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
WO2016069475A1 (en) 2014-10-27 2016-05-06 Aseko, Inc. Subcutaneous outpatient management
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
US9886556B2 (en) 2015-08-20 2018-02-06 Aseko, Inc. Diabetes management therapy advisor

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DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
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EP1039890B1 (en) * 1997-12-08 2004-03-17 Bristol-Myers Squibb Company Novel salts of metformin and method
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US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
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Also Published As

Publication number Publication date
PT1482919E (pt) 2007-07-25
MXPA04007183A (es) 2006-03-06
BRPI0502691A (pt) 2006-03-07
US9045438B2 (en) 2015-06-02
EP1482919B1 (en) 2007-05-02
DK1482919T3 (da) 2007-07-30
WO2003061643A1 (es) 2003-07-31
EP1482919A1 (en) 2004-12-08
DE60219963T2 (de) 2008-02-07
US20050239887A1 (en) 2005-10-27
ES2284829T3 (es) 2007-11-16
ATE361065T1 (de) 2007-05-15
DE60219963D1 (de) 2007-06-14
US20160051511A1 (en) 2016-02-25

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