IL144636A0 - Thioamide derivatives - Google Patents
Thioamide derivativesInfo
- Publication number
- IL144636A0 IL144636A0 IL14463600A IL14463600A IL144636A0 IL 144636 A0 IL144636 A0 IL 144636A0 IL 14463600 A IL14463600 A IL 14463600A IL 14463600 A IL14463600 A IL 14463600A IL 144636 A0 IL144636 A0 IL 144636A0
- Authority
- IL
- Israel
- Prior art keywords
- thioamide derivatives
- vcam
- vla
- asthma
- discovered
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/46—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/48—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Gyroscopes (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12047599P | 1999-02-18 | 1999-02-18 | |
| PCT/EP2000/001058 WO2000048994A1 (en) | 1999-02-18 | 2000-02-10 | Thioamide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL144636A0 true IL144636A0 (en) | 2002-05-23 |
Family
ID=22390545
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14463600A IL144636A0 (en) | 1999-02-18 | 2000-02-10 | Thioamide derivatives |
| IL144636A IL144636A (en) | 1999-02-18 | 2001-07-30 | Thioamide derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL144636A IL144636A (en) | 1999-02-18 | 2001-07-30 | Thioamide derivatives |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US6288267B1 (ru) |
| EP (1) | EP1154993B1 (ru) |
| JP (1) | JP2002537286A (ru) |
| KR (1) | KR100649819B1 (ru) |
| CN (1) | CN1213025C (ru) |
| AT (1) | ATE278664T1 (ru) |
| AU (1) | AU773388B2 (ru) |
| BR (1) | BR0008280A (ru) |
| CA (1) | CA2362831C (ru) |
| CZ (1) | CZ20012980A3 (ru) |
| DE (1) | DE60014588T2 (ru) |
| DK (1) | DK1154993T3 (ru) |
| ES (1) | ES2228458T3 (ru) |
| HK (1) | HK1044330A1 (ru) |
| HR (1) | HRP20010595B1 (ru) |
| HU (1) | HUP0200155A3 (ru) |
| ID (1) | ID30129A (ru) |
| IL (2) | IL144636A0 (ru) |
| MA (1) | MA26769A1 (ru) |
| NO (1) | NO20014018D0 (ru) |
| NZ (1) | NZ513254A (ru) |
| PL (1) | PL349461A1 (ru) |
| PT (1) | PT1154993E (ru) |
| RU (1) | RU2245874C2 (ru) |
| SI (1) | SI1154993T1 (ru) |
| TR (1) | TR200102399T2 (ru) |
| WO (1) | WO2000048994A1 (ru) |
| YU (1) | YU58701A (ru) |
| ZA (1) | ZA200106180B (ru) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6939855B2 (en) * | 1997-07-31 | 2005-09-06 | Elan Pharmaceuticals, Inc. | Anti-inflammatory compositions and method |
| US6680195B1 (en) * | 1997-11-26 | 2004-01-20 | Inhibitex, Inc. | Extracellular matrix-binding proteins from staphylococcus aureus |
| US6521626B1 (en) * | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| US6388084B1 (en) | 1999-12-06 | 2002-05-14 | Hoffmann-La Roche Inc. | 4-pyridinyl-n-acyl-l-phenylalanines |
| US6380387B1 (en) | 1999-12-06 | 2002-04-30 | Hoffmann-La Roche Inc. | 4-Pyrimidinyl-n-acyl-l phenylalanines |
| KR100937175B1 (ko) * | 2000-01-26 | 2010-01-19 | 미쓰이 가가쿠 가부시키가이샤 | 올레핀 중합체 |
| EP1270547A4 (en) | 2000-03-23 | 2005-07-13 | Ajinomoto Kk | NEW PHENYL ALANIDE DERIVATIVES |
| US6960597B2 (en) * | 2000-06-30 | 2005-11-01 | Orth-Mcneil Pharmaceutical, Inc. | Aza-bridged-bicyclic amino acid derivatives as α4 integrin antagonists |
| DK1317426T3 (da) * | 2000-09-14 | 2006-01-09 | Gruenenthal Gmbh | Betal-thio-aminosyrer |
| US20090297611A1 (en) * | 2003-07-31 | 2009-12-03 | Robinson Cynthia B | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a tyrosine kinase inhibitor, delta opioid receptor antagonist, neurokinin receptor antagonist, or vcam inhibitor for treatment of asthma or chronic obstructive pulmonary disease |
| US20050026879A1 (en) * | 2003-07-31 | 2005-02-03 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a tyrosine kinase inhibitor, delta opioid receptor antagonist, neurokinin receptor antagonist, or VCAM inhibitor for treatment of asthma or chronic obstructive pulmonary disease |
| US20050069227A1 (en) * | 2003-09-29 | 2005-03-31 | Mark Steele | Flexible package having integrated slit member |
| US20050176755A1 (en) * | 2003-10-31 | 2005-08-11 | Dyatkin Alexey B. | Aza-bridged-bicyclic amino acid derivatives as alpha4 integrin antagonists |
| CA2555594A1 (en) * | 2004-02-10 | 2005-08-25 | Janssen Pharmaceutica N.V. | Pyridazinones as antagonists of a4 integrins |
| MXPA06009099A (es) * | 2004-02-10 | 2007-02-02 | Johnson & Johnson | Piridazinona ureas como antagonistas de las integrinas alfa-4. |
| JP2007528397A (ja) * | 2004-03-10 | 2007-10-11 | メルク エンド カムパニー インコーポレーテッド | Ｖｌａ−４アンタゴニスト |
| EP1781686B1 (en) * | 2004-08-16 | 2009-05-06 | Merck & Co., Inc. | Vla-4 antagonists |
| US7641325B2 (en) * | 2004-10-04 | 2010-01-05 | Kodak Graphic Communications Group Canada | Non-conductive fluid droplet characterizing apparatus and method |
| WO2006081986A1 (en) * | 2005-02-07 | 2006-08-10 | F.Hoffmann-La Roche Ag | Bambuterol and integrin inhibitor combination |
| WO2006094640A2 (en) * | 2005-03-04 | 2006-09-14 | F.Hoffmann-La Roche Ag | Roflumilast and integrin inhibitor combination and method of treatment |
| CZ2005337A3 (cs) * | 2005-05-26 | 2007-01-10 | Universita Karlova v Praze, Farmaceutická fakulta v Hradci Králové | Antimykotické a antimykobakteriální thiosalicylanilidy a způsob jejich přípravy |
| ES2684821T3 (es) | 2005-12-29 | 2018-10-04 | Lexicon Pharmaceuticals, Inc. | Derivados de aminoácidos multicíclicos y métodos de su uso |
| AU2008219007A1 (en) | 2007-02-20 | 2008-08-28 | Merrimack Pharmaceuticals, Inc. | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
| ES2445755T3 (es) * | 2007-11-07 | 2014-03-05 | Celldex Therapeutics, Inc. | Anticuerpos que se unen a células dendríticas y epiteliales humanas 205 (DEC-205) |
| PL2288715T3 (pl) | 2008-04-11 | 2015-03-31 | Merrimack Pharmaceuticals Inc | Łączniki będące albuminą surowicy ludzkiej i ich koniugaty |
| KR20110112301A (ko) | 2008-11-18 | 2011-10-12 | 메리맥 파마슈티컬즈, 인크. | 인간 혈청 알부민 링커 및 그 콘쥬게이트 |
| US8343706B2 (en) * | 2010-01-25 | 2013-01-01 | International Business Machines Corporation | Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same |
| MX2014004025A (es) | 2011-10-17 | 2014-08-01 | Univ Muenster Wilhelms | Metodos de valoracion de riesgo de lmp y aparatos relacionados. |
| WO2014036520A1 (en) | 2012-08-30 | 2014-03-06 | Merrimack Pharmaceuticals, Inc. | Combination therapies comprising anti-erbb3 agents |
| KR20240015737A (ko) | 2018-10-30 | 2024-02-05 | 길리애드 사이언시즈, 인코포레이티드 | 알파4베타7 인테그린 억제제로서의 퀴놀린 유도체 |
| AU2019373245C1 (en) | 2018-10-30 | 2022-10-27 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4β7 integrin |
| CA3115820A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | Compounds for inhibition of .alpha.4.beta.7 integrin |
| WO2020092394A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
| US11578069B2 (en) | 2019-08-14 | 2023-02-14 | Gilead Sciences, Inc. | Compounds for inhibition of α4 β7 integrin |
| CN113683499B (zh) * | 2021-09-10 | 2024-01-30 | 上海皓鸿生物医药科技有限公司 | 一种制备杜韦利西布中间体的方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE584914A (ru) | 1958-11-24 | |||
| US3527793A (en) | 1967-08-18 | 1970-09-08 | Bristol Myers Co | Phenylglycine derivatives |
| IT1190378B (it) | 1985-06-21 | 1988-02-16 | Isf Spa | Derivati pirrolidonici |
| US5039805A (en) | 1988-12-08 | 1991-08-13 | Hoffmann-La Roche Inc. | Novel benzoic and phenylacetic acid derivatives |
| US5463116A (en) | 1991-07-30 | 1995-10-31 | Ajinomoto Co., Inc. | Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them |
| ATE210663T1 (de) | 1994-06-20 | 2001-12-15 | Takeda Chemical Industries Ltd | Kondensierte imidazolderivate, ihre herstellung und verwendung |
| US6306840B1 (en) | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
| US5804595A (en) | 1995-12-05 | 1998-09-08 | Regents Of The University Of Minnesota | Kappa opioid receptor agonists |
| DE19548709A1 (de) | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
| JP2000515493A (ja) * | 1996-03-29 | 2000-11-21 | ジー．ディー．サール アンド カンパニー | パラ―置換フェニレン誘導体 |
| JP2000506538A (ja) | 1996-03-29 | 2000-05-30 | ジー．ディー．サール アンド カンパニー | メタ―置換フェニレン誘導体 |
| DE19654483A1 (de) | 1996-06-28 | 1998-01-02 | Merck Patent Gmbh | Phenylalanin-Derivate |
| JP2002512625A (ja) * | 1997-05-29 | 2002-04-23 | メルク エンド カンパニー インコーポレーテッド | 細胞接着阻害薬としての複素環アミド化合物 |
| ES2206953T3 (es) * | 1997-06-23 | 2004-05-16 | Tanabe Seiyaku Co., Ltd. | Inhibidores de la adherencia celular mediada por alfa 4-beta 1. |
| PL338413A1 (en) * | 1997-07-31 | 2000-11-06 | Elan Pharm Inc | Compound of 4-amino phenylalanine type inhibiting adhesion of leucocytes through the meditation of vla-4 |
| EP0994895A1 (en) * | 1997-07-31 | 2000-04-26 | Elan Pharmaceuticals, Inc. | Dipeptide compounds which inhibit leukocyte adhesion mediated by vla-4 |
| CN1265672A (zh) * | 1997-07-31 | 2000-09-06 | 伊兰药品公司 | 能抑制由vla－4介导的白细胞粘连的磺酰化二肽化合物 |
| US6229011B1 (en) * | 1997-08-22 | 2001-05-08 | Hoffman-La Roche Inc. | N-aroylphenylalanine derivative VCAM-1 inhibitors |
| CA2300121A1 (en) * | 1997-08-22 | 1999-03-04 | F. Hoffmann-La Roche Ag | N-alkanoylphenylalanine derivatives |
| NZ502813A (en) * | 1997-08-22 | 2002-10-25 | F | N-aroylphenylalanine derivatives as inhibitors of the interaction between a4 containing integrins and VCAM-1 |
| WO1999033789A1 (en) * | 1997-12-23 | 1999-07-08 | Aventis Pharma Limited | SUBSTITUTED β-ALANINES |
| US6555562B1 (en) | 1998-02-26 | 2003-04-29 | Celltech R&D Limited | Phenylalanine derivatives |
| US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| GB9811159D0 (en) | 1998-05-22 | 1998-07-22 | Celltech Therapeutics Ltd | Chemical compounds |
-
2000
- 2000-02-10 HU HU0200155A patent/HUP0200155A3/hu unknown
- 2000-02-10 PL PL00349461A patent/PL349461A1/xx not_active Application Discontinuation
- 2000-02-10 CN CNB008043973A patent/CN1213025C/zh not_active Expired - Fee Related
- 2000-02-10 AT AT00903680T patent/ATE278664T1/de not_active IP Right Cessation
- 2000-02-10 JP JP2000599735A patent/JP2002537286A/ja active Pending
- 2000-02-10 NZ NZ513254A patent/NZ513254A/en unknown
- 2000-02-10 PT PT00903680T patent/PT1154993E/pt unknown
- 2000-02-10 IL IL14463600A patent/IL144636A0/xx active IP Right Grant
- 2000-02-10 CZ CZ20012980A patent/CZ20012980A3/cs unknown
- 2000-02-10 TR TR2001/02399T patent/TR200102399T2/xx unknown
- 2000-02-10 YU YU58701A patent/YU58701A/sh unknown
- 2000-02-10 KR KR1020017010495A patent/KR100649819B1/ko not_active IP Right Cessation
- 2000-02-10 ES ES00903680T patent/ES2228458T3/es not_active Expired - Lifetime
- 2000-02-10 WO PCT/EP2000/001058 patent/WO2000048994A1/en active IP Right Grant
- 2000-02-10 BR BR0008280-5A patent/BR0008280A/pt not_active Application Discontinuation
- 2000-02-10 ID IDW00200101770A patent/ID30129A/id unknown
- 2000-02-10 DE DE60014588T patent/DE60014588T2/de not_active Expired - Lifetime
- 2000-02-10 CA CA002362831A patent/CA2362831C/en not_active Expired - Fee Related
- 2000-02-10 SI SI200030513T patent/SI1154993T1/xx unknown
- 2000-02-10 DK DK00903680T patent/DK1154993T3/da active
- 2000-02-10 AU AU25475/00A patent/AU773388B2/en not_active Ceased
- 2000-02-10 RU RU2001124596/04A patent/RU2245874C2/ru not_active IP Right Cessation
- 2000-02-10 EP EP00903680A patent/EP1154993B1/en not_active Expired - Lifetime
- 2000-02-17 US US09/505,903 patent/US6288267B1/en not_active Expired - Fee Related
-
2001
- 2001-03-20 US US09/812,325 patent/US20020028933A1/en not_active Abandoned
- 2001-05-23 US US09/863,579 patent/US6458844B2/en not_active Expired - Fee Related
- 2001-05-23 US US09/864,032 patent/US6426348B1/en not_active Expired - Fee Related
- 2001-05-23 US US09/864,104 patent/US6423728B1/en not_active Expired - Fee Related
- 2001-05-23 US US09/863,567 patent/US6479666B2/en not_active Expired - Fee Related
- 2001-07-26 ZA ZA200106180A patent/ZA200106180B/en unknown
- 2001-07-30 IL IL144636A patent/IL144636A/en not_active IP Right Cessation
- 2001-08-08 MA MA26290A patent/MA26769A1/fr unknown
- 2001-08-10 HR HR20010595A patent/HRP20010595B1/xx not_active IP Right Cessation
- 2001-08-17 NO NO20014018A patent/NO20014018D0/no not_active Application Discontinuation
-
2002
- 2002-08-10 HK HK02105863A patent/HK1044330A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL144636A0 (en) | Thioamide derivatives | |
| LUC00155I2 (ru) | ||
| BG108806A (en) | IIb/IIIa CELL ADHESION INHIIBITORS, METHOD FOR THE PRODUCTION, PHARMACEUTCIAL COMPOSITION AND ADMINISTRATION THEREOF | |
| MXPA01008058A (es) | Composiciones deinhibidor de cicloxigenasa-2 teniendo un rapido inicio de efecto terapeutico. | |
| MY126972A (en) | 4-pyrimidinyl-n-acyl-l-phenylalanines | |
| WO2005051906A3 (en) | Heterocyclic inhibitors of mek and methods of use thereof | |
| TW200716648A (en) | Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia | |
| CA2505964A1 (en) | Pharmaceutical compositions and dosage forms of thalidomide | |
| BG105880A (en) | Compounds useful as anti-inflammatory agents | |
| YU40502A (sh) | 4-piridinil-n-acil-l-fenilalanini | |
| EP1539136A4 (en) | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | |
| AU2003224923A1 (en) | Heterocyclic amide derivatives as cytokine inhibitors | |
| DE60016181D1 (de) | C-16 ungesätigte fp-selektive prostaglandin analoge | |
| PL1716147T3 (pl) | Pochodne diazaspiropiperydyny jako inhibitory transportera 1 glicyny i transportera 2 glicyny | |
| EP1619184A3 (en) | Urea compounds as kinase inhibitors | |
| WO1998057910A3 (en) | Cyclooxygenase-i selective inhibitors and the use thereof as analgesic, antiinflammatory and antiarthritic agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |