IL139298A0 - Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same - Google Patents

Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Info

Publication number
IL139298A0
IL139298A0 IL13929899A IL13929899A IL139298A0 IL 139298 A0 IL139298 A0 IL 139298A0 IL 13929899 A IL13929899 A IL 13929899A IL 13929899 A IL13929899 A IL 13929899A IL 139298 A0 IL139298 A0 IL 139298A0
Authority
IL
Israel
Prior art keywords
gamma
preparing
same
acid derivatives
pharmaceutical preparations
Prior art date
Application number
IL13929899A
Other languages
English (en)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15097118&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL139298(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL139298A0 publication Critical patent/IL139298A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymerisation Methods In General (AREA)
IL13929899A 1998-05-15 1999-05-10 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same IL139298A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13311398 1998-05-15
PCT/US1999/010190 WO1999059573A1 (en) 1998-05-15 1999-05-10 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Publications (1)

Publication Number Publication Date
IL139298A0 true IL139298A0 (en) 2001-11-25

Family

ID=15097118

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13929899A IL139298A0 (en) 1998-05-15 1999-05-10 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
IL139298A IL139298A (en) 1998-05-15 2000-10-26 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL139298A IL139298A (en) 1998-05-15 2000-10-26 Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same

Country Status (37)

Country Link
US (1) US7309719B1 (is)
EP (1) EP1077692B1 (is)
JP (1) JP4612923B2 (is)
KR (1) KR100602047B1 (is)
CN (1) CN1303991C (is)
AR (1) AR020323A1 (is)
AT (1) ATE271864T1 (is)
AU (1) AU768277B2 (is)
BR (1) BR9910508B1 (is)
CA (1) CA2327285C (is)
CO (1) CO5021224A1 (is)
CR (1) CR6026A (is)
CU (1) CU23253B7 (is)
DE (1) DE69918977T2 (is)
DK (1) DK1077692T3 (is)
EG (1) EG26803A (is)
ES (1) ES2221385T3 (is)
GT (1) GT199900069A (is)
HK (1) HK1036586A1 (is)
HN (1) HN1999000072A (is)
HU (1) HU228771B1 (is)
ID (1) ID27724A (is)
IL (2) IL139298A0 (is)
IS (1) IS2233B (is)
MY (1) MY157878A (is)
NO (1) NO328959B1 (is)
NZ (1) NZ508015A (is)
PA (1) PA8472801A1 (is)
PE (1) PE20000556A1 (is)
PL (1) PL204921B1 (is)
PT (1) PT1077692E (is)
SI (1) SI1077692T1 (is)
SV (1) SV1999000064A (is)
TW (1) TWI243054B (is)
UY (1) UY25512A1 (is)
WO (1) WO1999059573A1 (is)
ZA (1) ZA200006484B (is)

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EP1384473A1 (en) * 2000-06-16 2004-01-28 Teva Pharmaceutical Industries Ltd. Stable gabapentin containing more than 20 ppm of chlorine ion
EP1430893A1 (en) * 2000-06-16 2004-06-23 Teva Pharmaceutical Industries Ltd. Stable gabapentin containing more than 20 ppm of chloride ion
US7056951B2 (en) * 2000-09-26 2006-06-06 Mutual Pharmaceutical Co., Inc. Stable solid dosage forms of amino acids and processes for producing same
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KR20070000439A (ko) * 2004-02-04 2007-01-02 알렘빅 리미티드 벤라팍신 히드로클로라이드의 방출연장형 코팅 미니정제
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NL2000281C2 (nl) 2005-11-02 2007-08-07 Pfizer Prod Inc Vaste farmaceutische samenstellingen die pregabaline bevatten.
WO2007107835A2 (en) * 2006-03-17 2007-09-27 Aurobindo Pharma Limited Stable liquid formulations of antiepileptic agents
DE102007019071A1 (de) 2007-04-23 2008-10-30 Ratiopharm Gmbh Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin
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HU230031B1 (hu) 2010-03-01 2015-05-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Pregabalint és izomaltot tartalmazó stabilizált gyógyszerkészítmény
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TR201005241A1 (tr) 2010-05-25 2012-01-23 Sanovel �La� San. Ve T�C. A.�. Kontrollü salım sağlayan pregabalin solüsyon formülasyonu.
PL3326615T3 (pl) 2010-11-15 2020-07-27 Neuroderm Ltd Ciągłe podawanie L-dopy, inhibitorów dekarboksylazy dopy, inhibitorów katecholo-o-metylotransferazy i ich kompozycji
HUE042425T2 (hu) 2012-06-05 2019-06-28 Neuroderm Ltd Apomorfint és szerves savakat tartalmazó készítmények és alkalmazásaik
CN103494796B (zh) * 2013-09-30 2016-01-20 浙江华义医药有限公司 普瑞巴林稳定的药物组合物及其制备方法
EP3099288A1 (en) 2014-01-28 2016-12-07 Sun Pharmaceutical Industries Ltd Stabilized gastroretentive tablets of pregabalin
EP4299128A3 (en) 2014-03-13 2024-04-17 Neuroderm Ltd. Dopa decarboxylase inhibitor compositions
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
EP2923694B1 (en) * 2014-03-27 2018-11-14 Sanovel Ilac Sanayi ve Ticaret A.S. Oral liquid pharmaceutical solution of gabapentin
EP2929878A1 (en) * 2014-04-09 2015-10-14 Arven Ilac Sanayi ve Ticaret A.S. Extended release formulations of gabapentin
WO2016187718A1 (en) 2015-05-26 2016-12-01 Isa Odidi Controlled extended release pregabalin
JP6919119B2 (ja) * 2017-01-23 2021-08-18 日新製薬株式会社 ３位が置換されたγ−アミノ酪酸誘導体を含有する圧縮固形医薬組成物。
JPWO2020071546A1 (ja) 2018-10-04 2021-09-02 株式会社 メドレックス 非水系溶媒により安定化された製剤
US10792262B1 (en) * 2019-07-29 2020-10-06 Saol International Limited Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives
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Also Published As

Publication number Publication date
PT1077692E (pt) 2004-12-31
BR9910508A (pt) 2001-01-02
PE20000556A1 (es) 2000-08-10
CR6026A (es) 2008-08-26
US7309719B1 (en) 2007-12-18
MY157878A (en) 2016-07-29
CO5021224A1 (es) 2001-03-27
BR9910508B1 (pt) 2012-01-24
PL344218A1 (en) 2001-10-08
CA2327285A1 (en) 1999-11-25
TWI243054B (en) 2005-11-11
JP2000034226A (ja) 2000-02-02
CN1303991C (zh) 2007-03-14
HU228771B1 (en) 2013-05-28
IS5666A (is) 2000-10-16
KR100602047B1 (ko) 2006-07-19
IS2233B (is) 2007-04-15
AU768277B2 (en) 2003-12-04
NO20005768D0 (no) 2000-11-14
ATE271864T1 (de) 2004-08-15
AU4073599A (en) 1999-12-06
EP1077692B1 (en) 2004-07-28
EG26803A (en) 2014-09-21
AR020323A1 (es) 2002-05-08
GT199900069A (es) 2000-11-04
IL139298A (en) 2009-07-20
HN1999000072A (es) 2000-06-05
DK1077692T3 (da) 2004-12-06
CN1301155A (zh) 2001-06-27
CU23253B7 (es) 2007-12-17
ZA200006484B (en) 2002-02-11
NO328959B1 (no) 2010-06-28
EP1077692A1 (en) 2001-02-28
NO20005768L (no) 2000-11-14
SV1999000064A (es) 2000-03-31
ID27724A (id) 2001-04-26
DE69918977D1 (de) 2004-09-02
JP4612923B2 (ja) 2011-01-12
UY25512A1 (es) 1999-07-19
HK1036586A1 (en) 2002-01-11
SI1077692T1 (en) 2004-10-31
CA2327285C (en) 2005-06-14
KR20010043611A (ko) 2001-05-25
NZ508015A (en) 2003-11-28
PA8472801A1 (es) 2001-12-14
ES2221385T3 (es) 2004-12-16
PL204921B1 (pl) 2010-02-26
WO1999059573A9 (en) 2000-05-04
WO1999059573A1 (en) 1999-11-25
HUP0102022A2 (hu) 2001-11-28
DE69918977T2 (de) 2005-07-28
HUP0102022A3 (en) 2002-11-28

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