IL138711A0 - Substituted indolealkanoic acids - Google Patents

Substituted indolealkanoic acids

Info

Publication number
IL138711A0
IL138711A0 IL13871199A IL13871199A IL138711A0 IL 138711 A0 IL138711 A0 IL 138711A0 IL 13871199 A IL13871199 A IL 13871199A IL 13871199 A IL13871199 A IL 13871199A IL 138711 A0 IL138711 A0 IL 138711A0
Authority
IL
Israel
Prior art keywords
indolealkanoic acids
substituted
substituted indolealkanoic
acids
indolealkanoic
Prior art date
Application number
IL13871199A
Other languages
English (en)
Original Assignee
Inst Pharmaceutical Discovery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Pharmaceutical Discovery filed Critical Inst Pharmaceutical Discovery
Publication of IL138711A0 publication Critical patent/IL138711A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IL13871199A 1998-03-31 1999-03-31 Substituted indolealkanoic acids IL138711A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8014398P 1998-03-31 1998-03-31
PCT/US1999/007116 WO1999050268A2 (en) 1998-03-31 1999-03-31 Substituted indolealkanoic acids

Publications (1)

Publication Number Publication Date
IL138711A0 true IL138711A0 (en) 2001-10-31

Family

ID=22155536

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13871199A IL138711A0 (en) 1998-03-31 1999-03-31 Substituted indolealkanoic acids
IL138711A IL138711A (en) 1998-03-31 2000-09-26 Induced indulalkanoic acids and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL138711A IL138711A (en) 1998-03-31 2000-09-26 Induced indulalkanoic acids and pharmaceutical compositions containing them

Country Status (29)

Country Link
US (9) US6214991B1 (hu)
EP (1) EP1066283B1 (hu)
JP (2) JP3494990B2 (hu)
KR (1) KR100584650B1 (hu)
CN (1) CN1205207C (hu)
AP (1) AP2000001929A0 (hu)
AT (1) ATE269861T1 (hu)
AU (1) AU774929B2 (hu)
BG (1) BG65446B1 (hu)
BR (1) BR9909358A (hu)
CA (1) CA2383983C (hu)
CZ (1) CZ300706B6 (hu)
DE (1) DE69918278T2 (hu)
EE (1) EE200000573A (hu)
ES (1) ES2224632T3 (hu)
HU (1) HUP0101672A3 (hu)
ID (1) ID27884A (hu)
IL (2) IL138711A0 (hu)
MX (1) MXPA02003122A (hu)
NO (1) NO20004900L (hu)
NZ (1) NZ507172A (hu)
OA (1) OA11622A (hu)
PL (1) PL201645B1 (hu)
SK (1) SK7522001A3 (hu)
TR (1) TR200002869T2 (hu)
TW (1) TWI243163B (hu)
WO (1) WO1999050268A2 (hu)
YU (1) YU59600A (hu)
ZA (1) ZA200005577B (hu)

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CN1205207C (zh) * 1998-03-31 2005-06-08 药品发现学会公司 取代的吲哚链烷酸
TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
CA2378047A1 (en) * 1999-07-15 2001-01-25 Methvin Isaac Heterocyclic compounds for the treatment of migraine
AU2001238718A1 (en) * 2000-03-02 2001-09-12 The Institutes For Pharmaceutical Discovery, Llc Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor
WO2001085983A2 (en) * 2000-05-09 2001-11-15 The Institute For Pharmaceutical Discovery Llc Methods for testing compounds useful for treating diabetic complications
JP2004517851A (ja) 2000-12-27 2004-06-17 バイエル アクチェンゲゼルシャフト 甲状腺受容体のリガンドとしてのインドール誘導体
ATE367812T1 (de) 2001-06-20 2007-08-15 Wyeth Corp Substituierte indolsäurederivate als inhibitoren von plasminogen-aktivator-inhibitor-1 (pai-1)
TWI224101B (en) 2001-06-20 2004-11-21 Wyeth Corp Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
AU2003210610B2 (en) 2002-01-18 2007-11-29 Aryx Therapeutics 5-HT3 receptor antagonists and methods of use
CA2395871A1 (en) * 2002-07-26 2004-01-26 The Institutes For Pharmaceutical Discovery, Llc Substituted indolealkanoic acids derivatives and formulations containing same for use in treatment of diabetic complications
US20060100255A1 (en) * 2002-07-26 2006-05-11 Van Zandt Michael C Substituted indolealkanoic acids derivative and formulations containing same for use in the treatment of diabetic complications
WO2004020408A1 (en) * 2002-08-29 2004-03-11 Merck & Co., Inc. Indoles having anti-diabetic activity
WO2004052855A2 (en) 2002-12-10 2004-06-24 Wyeth Substituted 3-carbonyl-1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
CN1726191A (zh) 2002-12-10 2006-01-25 惠氏公司 用作纤溶酶原激活物抑制剂-1(pai-1)的抑制剂的取代的吲哚氧代-乙酰氨基乙酸衍生物
UA80453C2 (en) 2002-12-10 2007-09-25 Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1)
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US7582773B2 (en) 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
US7332521B2 (en) 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7265148B2 (en) 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
US7446201B2 (en) 2003-09-25 2008-11-04 Wyeth Substituted heteroaryl benzofuran acids
US7141592B2 (en) 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
US7163954B2 (en) 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7411083B2 (en) 2003-09-25 2008-08-12 Wyeth Substituted acetic acid derivatives
US7442805B2 (en) 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
US7268159B2 (en) 2003-09-25 2007-09-11 Wyeth Substituted indoles
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AU2001238718A1 (en) * 2000-03-02 2001-09-12 The Institutes For Pharmaceutical Discovery, Llc Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor

Also Published As

Publication number Publication date
WO1999050268A3 (en) 1999-12-16
CA2383983C (en) 2009-09-29
US20010016661A1 (en) 2001-08-23
AU3459599A (en) 1999-10-18
US8163932B2 (en) 2012-04-24
AU774929B2 (en) 2004-07-15
BR9909358A (pt) 2000-12-12
JP2002509931A (ja) 2002-04-02
EP1066283B1 (en) 2004-06-23
DE69918278T2 (de) 2005-07-14
NZ507172A (en) 2003-10-31
US6730794B2 (en) 2004-05-04
CZ20003607A3 (cs) 2001-03-14
IL138711A (en) 2006-09-05
ATE269861T1 (de) 2004-07-15
US20080214540A1 (en) 2008-09-04
DE69918278D1 (de) 2004-07-29
SK7522001A3 (en) 2002-02-05
BG65446B1 (bg) 2008-08-29
US6214991B1 (en) 2001-04-10
US7304079B2 (en) 2007-12-04
TR200002869T2 (tr) 2000-12-21
CN1296485A (zh) 2001-05-23
HUP0101672A3 (en) 2002-05-28
MXPA02003122A (es) 2004-04-21
US20040235933A1 (en) 2004-11-25
CA2383983A1 (en) 1999-10-07
US7105514B2 (en) 2006-09-12
NO20004900D0 (no) 2000-09-29
ZA200005577B (en) 2002-02-11
KR20010042330A (ko) 2001-05-25
NO20004900L (no) 2000-10-17
CN1205207C (zh) 2005-06-08
PL201645B1 (pl) 2009-04-30
OA11622A (en) 2004-09-16
US20120270912A1 (en) 2012-10-25
WO1999050268A2 (en) 1999-10-07
KR100584650B1 (ko) 2006-05-30
US7659269B2 (en) 2010-02-09
AP2000001929A0 (en) 2000-09-30
PL348244A1 (en) 2002-05-20
CZ300706B6 (cs) 2009-07-22
JP2003155274A (ja) 2003-05-27
HUP0101672A2 (hu) 2002-04-29
BG104819A (en) 2001-05-31
ES2224632T3 (es) 2005-03-01
EE200000573A (et) 2002-04-15
TWI243163B (en) 2005-11-11
US20100137301A1 (en) 2010-06-03
EP1066283A2 (en) 2001-01-10
US20030018053A1 (en) 2003-01-23
US20100324039A1 (en) 2010-12-23
YU59600A (sh) 2002-12-10
JP3494990B2 (ja) 2004-02-09
US20070093530A1 (en) 2007-04-26
US6426344B2 (en) 2002-07-30
ID27884A (id) 2001-05-03

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