IL137672A0 - Derivatives of branched-chain lipophilic molecules and uses thereof - Google Patents

Derivatives of branched-chain lipophilic molecules and uses thereof

Info

Publication number
IL137672A0
IL137672A0 IL13767200A IL13767200A IL137672A0 IL 137672 A0 IL137672 A0 IL 137672A0 IL 13767200 A IL13767200 A IL 13767200A IL 13767200 A IL13767200 A IL 13767200A IL 137672 A0 IL137672 A0 IL 137672A0
Authority
IL
Israel
Prior art keywords
branched
derivatives
lipophilic molecules
chain lipophilic
chain
Prior art date
Application number
IL13767200A
Other languages
English (en)
Original Assignee
Dpharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dpharm Ltd filed Critical Dpharm Ltd
Priority to IL13767200A priority Critical patent/IL137672A0/xx
Priority to CNB01816806XA priority patent/CN100467476C/zh
Priority to ES01958325T priority patent/ES2338987T3/es
Priority to IL15424601A priority patent/IL154246A0/xx
Priority to US10/343,105 priority patent/US7186703B2/en
Priority to PCT/IL2001/000713 priority patent/WO2002011666A2/en
Priority to KR1020037001485A priority patent/KR100801207B1/ko
Priority to HU0301711A priority patent/HUP0301711A3/hu
Priority to AU8004301A priority patent/AU8004301A/xx
Priority to DE60141074T priority patent/DE60141074D1/de
Priority to JP2002517004A priority patent/JP2004505898A/ja
Priority to NZ523664A priority patent/NZ523664A/en
Priority to BR0112835-3A priority patent/BR0112835A/pt
Priority to AT01958325T priority patent/ATE455120T1/de
Priority to AU2001280043A priority patent/AU2001280043B2/en
Priority to CZ2003208A priority patent/CZ2003208A3/cs
Priority to CA2416808A priority patent/CA2416808C/en
Priority to EP01958325A priority patent/EP1305322B1/en
Publication of IL137672A0 publication Critical patent/IL137672A0/xx
Priority to US11/652,309 priority patent/US7687483B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/11—Esters of phosphoric acids with hydroxyalkyl compounds without further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
IL13767200A 2000-08-03 2000-08-03 Derivatives of branched-chain lipophilic molecules and uses thereof IL137672A0 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
IL13767200A IL137672A0 (en) 2000-08-03 2000-08-03 Derivatives of branched-chain lipophilic molecules and uses thereof
DE60141074T DE60141074D1 (de) 2000-08-03 2001-08-01 Derivate von kettenverzweigten lipophilen molekülen und deren verwendung
JP2002517004A JP2004505898A (ja) 2000-08-03 2001-08-01 分岐鎖状親油性分子の誘導体及びそれらの使用
IL15424601A IL154246A0 (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
US10/343,105 US7186703B2 (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
PCT/IL2001/000713 WO2002011666A2 (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
KR1020037001485A KR100801207B1 (ko) 2000-08-03 2001-08-01 분지-사슬 친지질성 분자의 유도체 및 그것의 사용
HU0301711A HUP0301711A3 (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
AU8004301A AU8004301A (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
CNB01816806XA CN100467476C (zh) 2000-08-03 2001-08-01 支化链亲脂性分子衍生物及其用途
ES01958325T ES2338987T3 (es) 2000-08-03 2001-08-01 Derivados de moleculas lipofilicas de cadena ramificada y usos de los mismos.
NZ523664A NZ523664A (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
BR0112835-3A BR0112835A (pt) 2000-08-03 2001-08-01 Derivados de moléculas lipofìlicas de cadeia ramificada e seus usos
AT01958325T ATE455120T1 (de) 2000-08-03 2001-08-01 Derivate von kettenverzweigten lipophilen molekülen und deren verwendung
AU2001280043A AU2001280043B2 (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
CZ2003208A CZ2003208A3 (cs) 2000-08-03 2001-08-01 Deriváty lipofilních molekul s větveným řetězcem a jejich použití
CA2416808A CA2416808C (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
EP01958325A EP1305322B1 (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof
US11/652,309 US7687483B2 (en) 2000-08-03 2007-01-11 Derivatives of branch-chain lipophilic molecular and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13767200A IL137672A0 (en) 2000-08-03 2000-08-03 Derivatives of branched-chain lipophilic molecules and uses thereof

Publications (1)

Publication Number Publication Date
IL137672A0 true IL137672A0 (en) 2001-10-31

Family

ID=11074480

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13767200A IL137672A0 (en) 2000-08-03 2000-08-03 Derivatives of branched-chain lipophilic molecules and uses thereof

Country Status (16)

Country Link
US (2) US7186703B2 (cs)
EP (1) EP1305322B1 (cs)
JP (1) JP2004505898A (cs)
KR (1) KR100801207B1 (cs)
CN (1) CN100467476C (cs)
AT (1) ATE455120T1 (cs)
AU (2) AU8004301A (cs)
BR (1) BR0112835A (cs)
CA (1) CA2416808C (cs)
CZ (1) CZ2003208A3 (cs)
DE (1) DE60141074D1 (cs)
ES (1) ES2338987T3 (cs)
HU (1) HUP0301711A3 (cs)
IL (1) IL137672A0 (cs)
NZ (1) NZ523664A (cs)
WO (1) WO2002011666A2 (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7582678B2 (en) 1997-07-09 2009-09-01 D-Pharm Limited Use of branched-chain fatty acids and derivatives thereof for the treatment of pain
US6518311B2 (en) * 1997-07-09 2003-02-11 D-Pharm Ltd. Use of branched-chain fatty acids and derivatives thereof for the treatment of pain
DE60143975D1 (de) * 2000-10-10 2011-03-10 Univ North Carolina Zusammensetzungen, die Phospholipase C Inhibitoren enthalten und Verfahren zur Erhöhung parazellulärer Permeabilität der Epithelbarriere und Endothelbarriere
EP1485107A1 (en) 2002-02-11 2004-12-15 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
CA2482903A1 (en) 2002-04-18 2003-10-23 Lynkeus Biotech Gmbh Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
US7148342B2 (en) 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
AU2004293013B2 (en) 2003-11-19 2011-04-28 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
EP1891080A2 (en) * 2005-05-26 2008-02-27 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
CA2606499C (en) 2005-05-26 2017-06-13 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
US8703179B2 (en) * 2006-05-11 2014-04-22 Kimberly-Clark Worldwide, Inc. Mucosal formulation
AU2008286954B2 (en) * 2007-08-10 2015-01-15 Basil Rigas Anti-inflammatory compounds and uses thereof
KR20110010694A (ko) * 2008-02-28 2011-02-07 헨리 포드 헬쓰 시스템 중추신경계 손상의 치료를 향상시키기 위해 기질 세포를 이용하는 조성물 및 방법
WO2010107487A2 (en) * 2009-03-18 2010-09-23 Wu Nian Lipid-drug conjugates for drug delivery
JP5853869B2 (ja) * 2012-06-07 2016-02-09 日油株式会社 ホスホリルコリン基含有化合物及びその製造法
BR112019010249A2 (pt) 2016-11-21 2019-09-10 Viking Therapeutics Inc método de tratamento de doença de armazenamento de glicogênio
US11707472B2 (en) 2017-06-05 2023-07-25 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis
KR20200138283A (ko) 2018-03-22 2020-12-09 바이킹 테라퓨틱스 인코포레이티드 결정질 형태, 및 결정질 형태의 화합물을 제조하는 방법
US12102646B2 (en) 2018-12-05 2024-10-01 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation

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Also Published As

Publication number Publication date
BR0112835A (pt) 2003-10-21
US20070135381A1 (en) 2007-06-14
US7186703B2 (en) 2007-03-06
AU2001280043B2 (en) 2007-05-24
DE60141074D1 (de) 2010-03-04
EP1305322A2 (en) 2003-05-02
CA2416808C (en) 2011-11-22
EP1305322A4 (en) 2005-04-13
WO2002011666A2 (en) 2002-02-14
KR20030024823A (ko) 2003-03-26
CZ2003208A3 (cs) 2003-10-15
EP1305322B1 (en) 2010-01-13
ATE455120T1 (de) 2010-01-15
HUP0301711A3 (en) 2007-05-29
JP2004505898A (ja) 2004-02-26
CN100467476C (zh) 2009-03-11
US7687483B2 (en) 2010-03-30
AU8004301A (en) 2002-02-18
ES2338987T3 (es) 2010-05-14
HUP0301711A2 (hu) 2003-09-29
CA2416808A1 (en) 2002-02-14
NZ523664A (en) 2004-07-30
WO2002011666A3 (en) 2002-07-11
AU2001280043B8 (en) 2002-02-18
CN1633440A (zh) 2005-06-29
US20030186897A1 (en) 2003-10-02
KR100801207B1 (ko) 2008-02-05

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