IL134152A - Spectral biological imaging of the eye - Google Patents

Spectral biological imaging of the eye

Info

Publication number
IL134152A
IL134152A IL13415298A IL13415298A IL134152A IL 134152 A IL134152 A IL 134152A IL 13415298 A IL13415298 A IL 13415298A IL 13415298 A IL13415298 A IL 13415298A IL 134152 A IL134152 A IL 134152A
Authority
IL
Israel
Prior art keywords
spectral
eye
light
eye tissue
image
Prior art date
Application number
IL13415298A
Other languages
English (en)
Hebrew (he)
Other versions
IL134152A0 (en
Original Assignee
Applied Spectral Imaging Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Spectral Imaging Ltd filed Critical Applied Spectral Imaging Ltd
Publication of IL134152A0 publication Critical patent/IL134152A0/xx
Publication of IL134152A publication Critical patent/IL134152A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14555—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for the eye fundus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J3/1256—Generating the spectrum; Monochromators using acousto-optic tunable filter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J3/26—Generating the spectrum; Monochromators using multiple reflection, e.g. Fabry-Perot interferometer, variable interference filters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2823—Imaging spectrometer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/45—Interferometric spectrometry
    • G01J3/453—Interferometric spectrometry by correlation of the amplitudes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/45—Interferometric spectrometry
    • G01J3/453—Interferometric spectrometry by correlation of the amplitudes
    • G01J3/4535—Devices with moving mirror
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/88—Image or video recognition using optical means, e.g. reference filters, holographic masks, frequency domain filters or spatial domain filters
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J2003/2866—Markers; Calibrating of scan
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6423—Spectral mapping, video display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Theoretical Computer Science (AREA)
  • Multimedia (AREA)
  • Ophthalmology & Optometry (AREA)
  • Optics & Photonics (AREA)
IL13415298A 1997-10-01 1998-09-29 Spectral biological imaging of the eye IL134152A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/942,122 US6198532B1 (en) 1991-02-22 1997-10-01 Spectral bio-imaging of the eye
PCT/US1998/020442 WO1999016353A1 (en) 1997-10-01 1998-09-29 Spectral bio-imaging of the eye

Publications (2)

Publication Number Publication Date
IL134152A0 IL134152A0 (en) 2001-04-30
IL134152A true IL134152A (en) 2004-02-19

Family

ID=25477606

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13415298A IL134152A (en) 1997-10-01 1998-09-29 Spectral biological imaging of the eye

Country Status (6)

Country Link
US (3) US6198532B1 (de)
EP (1) EP1026987A4 (de)
JP (1) JP2001517521A (de)
AU (1) AU9592098A (de)
IL (1) IL134152A (de)
WO (1) WO1999016353A1 (de)

Families Citing this family (331)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6198532B1 (en) * 1991-02-22 2001-03-06 Applied Spectral Imaging Ltd. Spectral bio-imaging of the eye
DE19648935B4 (de) * 1996-11-26 2008-05-15 IMEDOS Intelligente Optische Systeme der Medizin- und Messtechnik GmbH Vorrichtung und Verfahren zur Untersuchung von Gefäßen
US6453067B1 (en) * 1997-10-20 2002-09-17 Texas Instruments Incorporated Brightness gain using white segment with hue and gain correction
DE19758533B4 (de) * 1997-12-04 2005-09-29 Micronas Gmbh Verfahren zum Strukturieren einer Oberflächenschicht
US6637882B1 (en) * 1998-11-24 2003-10-28 Welch Allyn, Inc. Eye viewing device for retinal viewing through undilated pupil
US6549794B1 (en) 1999-09-24 2003-04-15 Cytometrics, Llc Single use disposable protective cap
JP4426032B2 (ja) * 1999-10-28 2010-03-03 株式会社トプコン 緑内障診断装置及び緑内障診断用記録媒体
DE19960586B4 (de) * 1999-12-15 2008-04-24 Siemens Ag Verfahren und Einrichtung zur Messung von Kenngrössen einer Probe durch Spektralanalyse
JP2001258853A (ja) * 2000-03-23 2001-09-25 Konan Medical Inc 眼底組織撮影装置
US7297326B2 (en) * 2000-08-21 2007-11-20 The General Hospital Corporation Ocular diagnosis of Alzheimer's disease
WO2002016951A2 (en) * 2000-08-21 2002-02-28 The General Hospital Corporation Methods for diagnosing a neurodegenerative condition
WO2002015818A2 (en) * 2000-08-23 2002-02-28 Philadelphia Ophthalmologic Imaging Systems, Inc. System and method for tele-ophthalmology
AU2001288425A1 (en) * 2000-08-25 2002-03-04 Cytometrics, Inc. System, method and computer program product for measuring blood properties form a spectral image
WO2002015788A1 (en) * 2000-08-25 2002-02-28 Krotkov Eric P System, method and computer program product for screening a spectral image
US20040058311A1 (en) * 2000-08-25 2004-03-25 Gary Fletcher Method and apparatus for measuring the hemoglobin concentration and/or hematocrit in whole blood using diffuse light
US6735331B1 (en) * 2000-09-05 2004-05-11 Talia Technology Ltd. Method and apparatus for early detection and classification of retinal pathologies
US6678398B2 (en) * 2000-09-18 2004-01-13 Sti Medical Systems, Inc. Dual mode real-time screening and rapid full-area, selective-spectral, remote imaging and analysis device and process
JP4241038B2 (ja) 2000-10-30 2009-03-18 ザ ジェネラル ホスピタル コーポレーション 組織分析のための光学的な方法及びシステム
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
FR2817986B1 (fr) * 2000-12-07 2003-03-28 Lyon Ecole Centrale Procede de classification d'une image en couleur selon la prise de vue en exterieur ou en interieur
AU2002233152A1 (en) * 2001-01-03 2002-07-16 Walthard Vilser Device and method for imaging, stimulation, measurement and therapy, in particular for the eye
US20020151774A1 (en) * 2001-03-01 2002-10-17 Umass/Worcester Ocular spectrometer and probe method for non-invasive spectral measurement
US7711403B2 (en) * 2001-04-05 2010-05-04 Rhode Island Hospital Non-invasive determination of blood components
GB2375679A (en) * 2001-04-09 2002-11-20 Patrick Kerr Retinal function camera using plural light wavelengths to produce a retinal function image showing haemoglobin oxygenation.
GB2378600A (en) * 2001-08-06 2003-02-12 Patrick Kerr Retinal function camera to determine retinal blood oxygenation.
EP2298361A3 (de) * 2001-04-27 2011-05-04 The General Hospital Corporation Okulare Diagnose der Alzheimer-Krankheit
EP2333523B1 (de) 2001-04-30 2020-04-08 The General Hospital Corporation Verfahren und vorrichtung zur verbesserung der bildklarheit und empfindlichkeit bei der optischen kohärenz-tomographie unter verwendung von dynamischer rückkopplung zur kontrolle der fokussierungseigenschaften und der kohärenzsteuerung
CA2473587C (en) 2001-05-01 2014-07-15 The General Hospital Corporation Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties
JP3731814B2 (ja) * 2001-05-07 2006-01-05 富士写真フイルム株式会社 蛍光画像表示装置
CA2450656A1 (en) * 2001-06-15 2002-12-27 The Cleveland Clinic Foundation Ratiometric quantitation of elicited eye autofluorescence
US7319755B2 (en) * 2001-08-03 2008-01-15 Waterstrike Incorporated Image altering apparatus and method for providing confidential viewing of a fundamental display image
US6980177B2 (en) * 2001-08-03 2005-12-27 Waterstrike Incorporated Sequential inverse encoding apparatus and method for providing confidential viewing of a fundamental display image
US6838074B2 (en) 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
JP2005508215A (ja) * 2001-08-30 2005-03-31 フィラデルフィア オフサルミック イメージング システムズ 糖尿病性網膜症の患者をスクリーニングするためのシステムおよび方法
US7039452B2 (en) * 2002-12-19 2006-05-02 The University Of Utah Research Foundation Method and apparatus for Raman imaging of macular pigments
US7355716B2 (en) * 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
US6665426B1 (en) * 2002-01-29 2003-12-16 West Virginia University Research Corporation Method of biometric identification of an individual and associated apparatus
US20110201924A1 (en) * 2002-04-30 2011-08-18 The General Hospital Corporation Method and Apparatus for Improving Image Clarity and Sensitivity in Optical Tomography Using Dynamic Feedback to Control Focal Properties and Coherence Gating
DE60323625D1 (de) * 2002-05-03 2008-10-30 Vialogy Llc Verfahren zur charakterisierung der ausgangssignale eines microarrays
JP4059010B2 (ja) * 2002-06-06 2008-03-12 株式会社日立製作所 投射型映像表示装置
US6926407B2 (en) 2002-06-28 2005-08-09 Trefford Simpson Apparatus and method for measuring a hue of a predetermined primary color in reflected light
US7222961B2 (en) * 2002-08-05 2007-05-29 Kestrel Corporation Method for detecting a functional signal in retinal images
US6992775B2 (en) * 2002-08-29 2006-01-31 Kestrel Corporation Hyperspectral retinal imager
US20040124366A1 (en) * 2002-10-02 2004-07-01 Haishan Zeng Apparatus and methods relating to high speed spectroscopy and excitation-emission matrices
US20040254438A1 (en) * 2003-01-09 2004-12-16 The Regents Of The University Of California Implantable devices and methods for measuring intraocular, subconjunctival or subdermal pressure and/or analyte concentration
WO2004064615A2 (en) 2003-01-23 2004-08-05 Board Of Regents, The University Of Texas System Method and apparatus for diagnosing neovascularized tissues
US7643153B2 (en) * 2003-01-24 2010-01-05 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
JP2006516739A (ja) 2003-01-24 2006-07-06 ザ・ジェネラル・ホスピタル・コーポレイション 低コヒーレンス干渉計を用いて組織を識別するためのシステムおよび方法
US6985232B2 (en) * 2003-03-13 2006-01-10 Tokyo Electron Limited Scatterometry by phase sensitive reflectometer
US20040193095A1 (en) * 2003-03-29 2004-09-30 Shadduck John H. Implants for treating ocular hypertension, methods of use and methods of fabrication
US7267648B2 (en) * 2003-03-31 2007-09-11 Olympus Corporation Magnifying image pickup unit for an endoscope, an endoscope for in vivo cellular observation that uses it, and endoscopic, in vivo cellular observation methods
EP2436307B1 (de) 2003-03-31 2015-10-21 The General Hospital Corporation Fleckenreduzierung bei der optischen Kohärenztomografie durch pfadlängencodierte Winkelmischung
DE10314944A1 (de) * 2003-04-02 2004-10-14 Carl Zeiss Meditec Ag Beleuchtungs- und Bestrahlungseinheit für ophthalmologische Geräte
US7545963B2 (en) * 2003-04-04 2009-06-09 Lumidigm, Inc. Texture-biometrics sensor
US7668350B2 (en) 2003-04-04 2010-02-23 Lumidigm, Inc. Comparative texture analysis of tissue for biometric spoof detection
US7539330B2 (en) * 2004-06-01 2009-05-26 Lumidigm, Inc. Multispectral liveness determination
US7751594B2 (en) 2003-04-04 2010-07-06 Lumidigm, Inc. White-light spectral biometric sensors
US7627151B2 (en) * 2003-04-04 2009-12-01 Lumidigm, Inc. Systems and methods for improved biometric feature definition
US7460696B2 (en) 2004-06-01 2008-12-02 Lumidigm, Inc. Multispectral imaging biometrics
US7394919B2 (en) * 2004-06-01 2008-07-01 Lumidigm, Inc. Multispectral biometric imaging
EP1611541B1 (de) 2003-04-04 2010-12-15 Lumidigm, Inc. Multispektralbiometriesensor
US7400754B2 (en) * 2003-04-08 2008-07-15 The Regents Of The University Of California Method and apparatus for characterization of chromophore content and distribution in skin using cross-polarized diffuse reflectance imaging
JP2006525054A (ja) * 2003-05-01 2006-11-09 ミレニアム・ダイエット・アンド・ニュートリスーティカルズ・リミテッド 黄斑色素の分布の測定
EP1639330B1 (de) 2003-06-06 2008-10-08 The General Hospital Corporation Wellenlängenabstimmbare lichtquelle
US20060268231A1 (en) * 2003-07-03 2006-11-30 Medibell Medicall Vision Technologies, Ltd. Illumination method and system for obtaining color images by transcleral ophthalmic illumination
US7356365B2 (en) * 2003-07-09 2008-04-08 Glucolight Corporation Method and apparatus for tissue oximetry
DE20313745U1 (de) * 2003-09-02 2003-11-20 Oculus Optikgeraete Gmbh Ophthalmologisches Analysesystem
US7321791B2 (en) 2003-09-23 2008-01-22 Cambridge Research And Instrumentation, Inc. Spectral imaging of deep tissue
US8634607B2 (en) 2003-09-23 2014-01-21 Cambridge Research & Instrumentation, Inc. Spectral imaging of biological samples
WO2005033678A1 (ja) 2003-10-03 2005-04-14 Olympus Corporation 画像処理装置及び画像処理方法
WO2005036143A1 (ja) * 2003-10-10 2005-04-21 Hamamatsu Photonics K.K. 蛍光色素の濃度を定量する方法およびシステム
US7920908B2 (en) 2003-10-16 2011-04-05 David Hattery Multispectral imaging for quantitative contrast of functional and structural features of layers inside optically dense media such as tissue
CN1875242A (zh) 2003-10-27 2006-12-06 通用医疗公司 用于使用频域干涉测量法进行光学成像的方法和设备
US7364297B2 (en) * 2003-10-28 2008-04-29 Welch Allyn, Inc. Digital documenting ophthalmoscope
US7708403B2 (en) * 2003-10-30 2010-05-04 Welch Allyn, Inc. Apparatus and method for diagnosis of optically identifiable ophthalmic conditions
US20090270717A1 (en) * 2008-04-25 2009-10-29 Welch Allyn, Inc. Apparatus and method for diagnosis of optically identifiable ophthalmic conditions
US7575321B2 (en) * 2003-10-30 2009-08-18 Welch Allyn, Inc. Apparatus and method of diagnosis of optically identifiable ophthalmic conditions
WO2005054780A1 (en) * 2003-11-28 2005-06-16 The General Hospital Corporation Method and apparatus for three-dimensional spectrally encoded imaging
US7263213B2 (en) * 2003-12-11 2007-08-28 Lumidigm, Inc. Methods and systems for estimation of personal characteristics from biometric measurements
US7510849B2 (en) * 2004-01-29 2009-03-31 Glucolight Corporation OCT based method for diagnosis and therapy
GB2427825B (en) * 2004-01-30 2007-08-01 Univ Brown Non-Invasive Spectroscopy Of Mammalian Tissues
US7512436B2 (en) * 2004-02-12 2009-03-31 The Regents Of The University Of Michigan Method of evaluating metabolism of the eye
DE102004008675B4 (de) * 2004-02-20 2009-05-07 Imedos Gmbh Bildgebendes Verfahren zur Erfassung medizinisch relevanter Unterschiede von Strukturen und Eigenschaften eines Untersuchungsobjektes und dazu geeignete Vorrichtung
US7524064B2 (en) * 2004-03-09 2009-04-28 Research Foundation Of The State University Of New York Apparatus and method for assessing retinal damage
DE102004011631B4 (de) * 2004-03-10 2011-03-24 Ott, Lutz, Dipl.-Ing. Verfahren und Vorrichtung zur tiefenselektiven Detektion von Spontanaktivitäten und allgemeinen Muskelaktivitäten
AU2005226667B2 (en) * 2004-03-19 2010-04-01 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College A method for evaluating relative oxygen saturation in body tissues
US20060155178A1 (en) * 2004-03-26 2006-07-13 Vadim Backman Multi-dimensional elastic light scattering
US20080144967A1 (en) * 2004-03-30 2008-06-19 Waterstrike Incorporated Confidential Viewing System Utilizing Spatial Multiplexing
DE102004016435B4 (de) * 2004-03-31 2009-05-28 Imedos Gmbh Verfahren zur spektralphotometrischen Ermittlung der Sauerstoffsättigung des Blutes in optisch zugänglichen Blutgefäßen
JP4750786B2 (ja) * 2004-05-29 2011-08-17 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィ（ｏｃｔ）イメージングにおける屈折層を用いた色分散補償プロセス、システム及びソフトウェア構成
CA2569440A1 (en) * 2004-06-01 2006-09-08 Lumidigm, Inc. Multispectral imaging biometrics
US8229185B2 (en) 2004-06-01 2012-07-24 Lumidigm, Inc. Hygienic biometric sensors
JP4995720B2 (ja) 2004-07-02 2012-08-08 ザ ジェネラル ホスピタル コーポレイション ダブルクラッドファイバを有する内視鏡撮像プローブ
DE102004037479A1 (de) * 2004-08-03 2006-03-16 Carl Zeiss Meditec Ag Fourier-Domain OCT Ray-Tracing am Auge
US8081316B2 (en) 2004-08-06 2011-12-20 The General Hospital Corporation Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography
US8787630B2 (en) * 2004-08-11 2014-07-22 Lumidigm, Inc. Multispectral barcode imaging
US8036727B2 (en) * 2004-08-11 2011-10-11 Glt Acquisition Corp. Methods for noninvasively measuring analyte levels in a subject
US7254429B2 (en) 2004-08-11 2007-08-07 Glucolight Corporation Method and apparatus for monitoring glucose levels in a biological tissue
JP5334415B2 (ja) 2004-08-24 2013-11-06 ザ ジェネラル ホスピタル コーポレイション 試料の機械的歪み及び弾性的性質を測定するプロセス、システム及びソフトウェア
KR20070058523A (ko) 2004-08-24 2007-06-08 더 제너럴 하스피탈 코포레이션 혈관절편 영상화 방법 및 장치
WO2006039091A2 (en) 2004-09-10 2006-04-13 The General Hospital Corporation System and method for optical coherence imaging
JP4997112B2 (ja) 2004-09-29 2012-08-08 ザ ジェネラル ホスピタル コーポレイション 少なくとも１つの電磁放射を伝送させるための装置およびその製造方法
WO2006047408A2 (en) * 2004-10-22 2006-05-04 Vanderbilt University On-chip polarimetry for high-throughput screening of nanoliter and smaller sample volumes
EP1807803A1 (de) * 2004-10-26 2007-07-18 Koninklijke Philips Electronics N.V. Verbesserung unscharfer bildteile
US20080007734A1 (en) * 2004-10-29 2008-01-10 The General Hospital Corporation System and method for providing Jones matrix-based analysis to determine non-depolarizing polarization parameters using polarization-sensitive optical coherence tomography
WO2006058049A1 (en) 2004-11-24 2006-06-01 The General Hospital Corporation Common-path interferometer for endoscopic oct
US8224425B2 (en) * 2005-04-04 2012-07-17 Hypermed Imaging, Inc. Hyperspectral imaging in diabetes and peripheral vascular disease
CA2631564A1 (en) 2004-11-29 2006-06-01 Hypermed, Inc. Medical hyperspectral imaging for evaluation of tissue and tumor
US8548570B2 (en) 2004-11-29 2013-10-01 Hypermed Imaging, Inc. Hyperspectral imaging of angiogenesis
US8922781B2 (en) 2004-11-29 2014-12-30 The General Hospital Corporation Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
US7365856B2 (en) 2005-01-21 2008-04-29 Carl Zeiss Meditec, Inc. Method of motion correction in optical coherence tomography imaging
EP1846869B1 (de) 2005-01-27 2011-10-05 Cambridge Research & Instrumentation, Inc. Klassifizierung der bildeigenschaften
EP1698272B1 (de) * 2005-03-04 2012-12-05 FUJIFILM Corporation Endoskop und Bildverarbeitungseinrichtung
JP4637620B2 (ja) * 2005-03-18 2011-02-23 富士フイルム株式会社 内視鏡システム装置
WO2006100685A2 (en) * 2005-03-25 2006-09-28 Cnoga Holdings Ltd Optical sensor device and image processing unit for measuring chemical concentrations, chemical saturations and biophysical parameters
US7474775B2 (en) * 2005-03-31 2009-01-06 University Of Iowa Research Foundation Automatic detection of red lesions in digital color fundus photographs
US8971984B2 (en) 2005-04-04 2015-03-03 Hypermed Imaging, Inc. Hyperspectral technology for assessing and treating diabetic foot and tissue disease
CA2604829C (en) 2005-04-04 2018-05-15 Hypermed, Inc. Hyperspectral imaging in diabetes and peripheral vascular disease
US7805009B2 (en) 2005-04-06 2010-09-28 Carl Zeiss Meditec, Inc. Method and apparatus for measuring motion of a subject using a series of partial images from an imaging system
EP1874178A4 (de) 2005-04-13 2009-12-09 Glucolight Corp Verfahren zur datenreduzierung und kalibrierung eines blutzuckermonitors auf oct-basis
US7801338B2 (en) * 2005-04-27 2010-09-21 Lumidigm, Inc. Multispectral biometric sensors
JP5684452B2 (ja) 2005-04-28 2015-03-11 ザ ジェネラル ホスピタル コーポレイション 光干渉測定法により解剖学的構造に関連する情報を評価するためのシステム、方法及びソフトウエア装置
EP1887926B1 (de) * 2005-05-31 2014-07-30 The General Hospital Corporation System und verfahren die spektrale interferometrietechniken zur codierungsüberlagerung zur bildgebung benutzen
US7774036B2 (en) * 2005-06-07 2010-08-10 Oxymap Ehf Automatic registration of images
US8255039B2 (en) * 2006-09-29 2012-08-28 Tearscience, Inc. Meibomian gland illuminating and imaging
ES2354287T3 (es) 2005-08-09 2011-03-11 The General Hospital Corporation Aparato y método para realizar una desmodulación en cuadratura por polarización en tomografía de coherencia óptica.
KR20080066705A (ko) 2005-09-29 2008-07-16 더 제너럴 하스피탈 코포레이션 점진적으로 증가하는 분해능을 이용하여 하나 이상의 생물학적 샘플을 관찰 및 분석하기 위한 방법 및 장치
US7889348B2 (en) * 2005-10-14 2011-02-15 The General Hospital Corporation Arrangements and methods for facilitating photoluminescence imaging
US20070092115A1 (en) * 2005-10-26 2007-04-26 Usher David B Method and system for detecting biometric liveness
US20070179368A1 (en) * 2005-10-27 2007-08-02 Northwestern University Method of recognizing abnormal tissue using the detection of early increase in microvascular blood content
US20090203977A1 (en) * 2005-10-27 2009-08-13 Vadim Backman Method of screening for cancer using parameters obtained by the detection of early increase in microvascular blood content
US20070129615A1 (en) * 2005-10-27 2007-06-07 Northwestern University Apparatus for recognizing abnormal tissue using the detection of early increase in microvascular blood content
US9314164B2 (en) 2005-10-27 2016-04-19 Northwestern University Method of using the detection of early increase in microvascular blood content to distinguish between adenomatous and hyperplastic polyps
JP5680826B2 (ja) * 2006-01-10 2015-03-04 ザ ジェネラル ホスピタル コーポレイション １以上のスペクトルを符号化する内視鏡技術によるデータ生成システム
US7876973B2 (en) * 2006-01-12 2011-01-25 Integrity Applications Incorporated Edge ringing artifact suppression methods and apparatuses
EP2289397A3 (de) 2006-01-19 2011-04-06 The General Hospital Corporation Verfahren und Systeme zur optischen Bildgebung von epithelialen Luminalorganen durch Strahlenabtastung dieser
US20070223006A1 (en) * 2006-01-19 2007-09-27 The General Hospital Corporation Systems and methods for performing rapid fluorescence lifetime, excitation and emission spectral measurements
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
WO2007084959A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and methods for providing mirror tunnel microscopy
EP2659851A3 (de) 2006-02-01 2014-01-15 The General Hospital Corporation Vorrichtung zur Anwendung mehrerer elektromagnetischer Strahlungen auf einer Probe
US10426548B2 (en) * 2006-02-01 2019-10-01 The General Hosppital Corporation Methods and systems for providing electromagnetic radiation to at least one portion of a sample using conformal laser therapy procedures
EP1986562B1 (de) * 2006-02-01 2015-04-08 The General Hospital Corporation Vorrichtung zur steuerung mindestens einer von mindestens zwei sektionen mindestens einer faser
EP3143926B1 (de) 2006-02-08 2020-07-01 The General Hospital Corporation Verfahren, anordnungen und systeme zum abrufen von informationen im zusammenhang mit einer anatomischen probe mithilfe eines optischen mikroskops
US20070224694A1 (en) * 2006-02-10 2007-09-27 Puchalski Daniel M Method and system for hyperspectral detection of animal diseases
EP1987318B1 (de) 2006-02-24 2015-08-12 The General Hospital Corporation Verfahren und systeme zur durchführung von winkelaufgelöster optischer kohärenztomografie im fourier-bereich
US7734107B2 (en) * 2006-02-24 2010-06-08 Sony Corporation System and method for performing wavelet-based texture feature extraction and classification
JP2009533076A (ja) * 2006-03-01 2009-09-17 ザ ジェネラル ホスピタル コーポレイション 光吸収体をマクロファージに標的化することによるアテローム班の細胞特異的レーザー治療を提供するシステム及び方法
WO2007109540A2 (en) * 2006-03-17 2007-09-27 The General Hospital Corporation Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral domain low coherence interferometry
US7742173B2 (en) * 2006-04-05 2010-06-22 The General Hospital Corporation Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
US8243999B2 (en) 2006-05-03 2012-08-14 Ut-Battelle, Llc Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data
JP2009536740A (ja) 2006-05-10 2009-10-15 ザ ジェネラル ホスピタル コーポレイション サンプルの周波数領域画像形成を提供するためのプロセス、構成およびシステム
WO2007133964A2 (en) * 2006-05-12 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
US8131348B2 (en) * 2006-05-12 2012-03-06 Northshore University Healthsystem Systems, methods and apparatuses of elastic light scattering spectroscopy and low coherence enhanced backscattering spectroscopy
AU2007254086B2 (en) * 2006-05-19 2013-03-21 Northshore University Health System Method and apparatus for recognizing abnormal tissue using the detection of early increase in microvascular blood content
US10010277B2 (en) * 2006-06-22 2018-07-03 The General Hospital Corporation Cancer detection by optical measurement of compression-induced transients
US7791686B2 (en) * 2006-06-23 2010-09-07 Waterstrike Incorporated LCD-based confidential viewing apparatus utilizing auto-inversion masking
US8644911B1 (en) 2006-06-30 2014-02-04 Hypermed Imaging, Inc. OxyVu-1 hyperspectral tissue oxygenation (HTO) measurement system
US7995808B2 (en) 2006-07-19 2011-08-09 Lumidigm, Inc. Contactless multispectral biometric capture
US8355545B2 (en) 2007-04-10 2013-01-15 Lumidigm, Inc. Biometric detection using spatial, temporal, and/or spectral techniques
CN103336941A (zh) 2006-07-19 2013-10-02 光谱辨识公司 多重生物测定多谱成像器
US8175346B2 (en) 2006-07-19 2012-05-08 Lumidigm, Inc. Whole-hand multispectral biometric imaging
US7804984B2 (en) * 2006-07-31 2010-09-28 Lumidigm, Inc. Spatial-spectral fingerprint spoof detection
US7801339B2 (en) * 2006-07-31 2010-09-21 Lumidigm, Inc. Biometrics with spatiospectral spoof detection
US7538872B1 (en) * 2006-08-02 2009-05-26 Butler Eugene W Diagnostic methods and apparatus for directed energy applications
US7800746B2 (en) * 2006-08-11 2010-09-21 Northwestern University Method for identifying refractive-index fluctuations of a target
CN101589301B (zh) 2006-08-25 2012-11-07 通用医疗公司 利用体积测定过滤技术来增强光学相干断层成像的装置和方法
US8249695B2 (en) 2006-09-29 2012-08-21 Tearscience, Inc. Meibomian gland imaging
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
US8244021B2 (en) 2006-12-20 2012-08-14 Ventana Medical Systems, Inc. Quantitative, multispectral image analysis of tissue specimens stained with quantum dots
JP5019866B2 (ja) * 2006-12-25 2012-09-05 オリンパス株式会社 蛍光内視鏡及び蛍光内視鏡の作動方法
US7949019B2 (en) 2007-01-19 2011-05-24 The General Hospital Wavelength tuning source based on a rotatable reflector
US20080206804A1 (en) * 2007-01-19 2008-08-28 The General Hospital Corporation Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis
EP2102583A2 (de) 2007-01-19 2009-09-23 The General Hospital Corporation Vorrichtung und verfahren zur steuerung der entfernungsmessungstiefe bei der bildgebung im optischen frequenzbereich
CN101589421B (zh) 2007-01-26 2013-01-09 日本电气株式会社 图像处理设备、方法和显示器
US20080234586A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome using exemplary laser speckle imaging procedure
CN101641049A (zh) 2007-03-21 2010-02-03 光谱辨识公司 基于局部一致特征的生物测定
US9176319B2 (en) 2007-03-23 2015-11-03 The General Hospital Corporation Methods, arrangements and apparatus for utilizing a wavelength-swept laser using angular scanning and dispersion procedures
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
US20080255545A1 (en) * 2007-04-10 2008-10-16 Mansfield John M Apparatus and method for treating the inside of an eye
WO2008131082A1 (en) 2007-04-17 2008-10-30 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy techniques
WO2008137637A2 (en) * 2007-05-04 2008-11-13 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using brillouin microscopy
WO2008144496A1 (en) * 2007-05-18 2008-11-27 Vanderbilt University Improved interferometric detection system and method
US9326715B1 (en) * 2007-07-02 2016-05-03 Hypermed Imaging, Inc. OxyVu-1 hyperspectral tissue oxygenation (HTO) measurement system
CN101347334B (zh) * 2007-07-19 2012-09-05 深圳迈瑞生物医疗电子股份有限公司 血氧饱和度测量方法和装置
US8132911B2 (en) * 2007-07-26 2012-03-13 The United States Of America As Represented By The Department Of Health And Human Services Fundus photo-stimulation system and method
EP2173254A2 (de) * 2007-07-31 2010-04-14 The General Hospital Corporation System und verfahren zur bereitstellung von strahlerfassungsmustern für hochgeschwindigkeits-abbildungen optischer dopplerfrequenzdomänen
US7828440B2 (en) * 2007-08-17 2010-11-09 Peyman Gholam A Method of detecting glaucoma
US7549752B2 (en) * 2007-08-17 2009-06-23 Peyman Gholam A Method of detecting glaucoma
EP2191254B1 (de) 2007-08-31 2017-07-19 The General Hospital Corporation System und verfahren für selbstinterferenz-fluoreszenzmikroskopie und damit assoziiertes rechnerzugriffsmedium
WO2009039466A1 (en) 2007-09-20 2009-03-26 Vanderbilt University Free solution measurement of molecular interactions by backscattering interferometry
US20090099428A1 (en) * 2007-10-03 2009-04-16 Evasight Instruments Inc. Method of blood oxygen saturation by ophthalmic measurement
US7933021B2 (en) * 2007-10-30 2011-04-26 The General Hospital Corporation System and method for cladding mode detection
AU2008320965B2 (en) * 2007-11-13 2014-10-23 The Regents Of The University Of Michigan Method and apparatus for detecting diseases associated with the eye
US8124936B1 (en) * 2007-12-13 2012-02-28 The United States Of America As Represented By The Secretary Of The Army Stand-off chemical detector
DE102007055923A1 (de) * 2007-12-21 2009-06-25 Carl Zeiss Surgical Gmbh Verfahren zur Ermittlung von Eigenschaften und/oder der Position charakteristischer Augenbestandteile
US8662667B2 (en) 2007-12-21 2014-03-04 Carl Zeiss Meditec Ag Ophthalmologic visualization system
US9332942B2 (en) * 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
US11123047B2 (en) 2008-01-28 2021-09-21 The General Hospital Corporation Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood
WO2009105579A2 (en) * 2008-02-19 2009-08-27 Garahan Patrick J Portable holder for beverage containers
WO2009111542A2 (en) 2008-03-04 2009-09-11 Glucolight Corporation Methods and systems for analyte level estimation in optical coherence tomography
US8109634B2 (en) * 2008-03-05 2012-02-07 Tamir Gil Snapshot spectral imaging of the eye
JP2011515189A (ja) * 2008-03-27 2011-05-19 ニューロプティックス コーポレイション 眼の画像化
US8128227B2 (en) * 2008-04-15 2012-03-06 The United States Of America As Represented By The Secretary Of Agriculture Method to detect transmissible spongiform encephalopathies via electroretinogram
JP5607610B2 (ja) 2008-05-07 2014-10-15 ザ ジェネラル ホスピタル コーポレイション 構造の特徴を決定する装置、装置の作動方法およびコンピュータアクセス可能な媒体
JP5795531B2 (ja) 2008-06-20 2015-10-14 ザ ジェネラル ホスピタル コーポレイション フューズドファイバオプティックカプラ構造、及びその使用方法
US7585291B1 (en) * 2008-07-03 2009-09-08 Michael Campion Eye coloring systems
WO2010009136A2 (en) 2008-07-14 2010-01-21 The General Hospital Corporation Apparatus and methods for color endoscopy
US8406859B2 (en) 2008-08-10 2013-03-26 Board Of Regents, The University Of Texas System Digital light processing hyperspectral imaging apparatus
KR101679438B1 (ko) * 2008-09-18 2016-11-24 세다르스-신나이 메디칼 센터 알츠하이머병의 검출을 위한 광학적 방법
US8218838B2 (en) * 2008-11-03 2012-07-10 Ut-Battelle, Llc Method and system for assigning a confidence metric for automated determination of optic disc location
CN102227747B (zh) * 2008-11-27 2014-06-04 皇家飞利浦电子股份有限公司 产生未染色生物标本的多色图像
US8937724B2 (en) 2008-12-10 2015-01-20 The General Hospital Corporation Systems and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling
US9885834B2 (en) 2009-01-08 2018-02-06 Northwestern University Probe apparatus for measuring depth-limited properties with low-coherence enhanced backscattering
EP2385786A4 (de) * 2009-01-08 2013-07-03 American Biooptics Llc Sondenvorrichtung zur erkennung von gewebeanomalien
WO2010085775A2 (en) 2009-01-26 2010-07-29 The General Hospital Corporation System, method and computer-accessible medium for providing wide-field superresolution microscopy
EP2394336B1 (de) 2009-02-04 2023-05-24 The General Hospital Corporation Vorrichtung und verfahren zur verwendung einer optischen hochgeschwindigkeits-wellenlängenabstimmungsquelle
US9351642B2 (en) 2009-03-12 2016-05-31 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
JP5316161B2 (ja) * 2009-03-27 2013-10-16 ソニー株式会社 観察装置
CA3010578C (en) 2009-04-01 2021-03-09 Tearscience, Inc. Ocular surface interferometry (osi) devices, systems, and methods for imaging, processing, and/or displaying an ocular tear film and/or measuring ocular tear film layer thickness(es)
WO2010143208A2 (en) * 2009-06-12 2010-12-16 Oxymap Temporal oximeter
US8308298B2 (en) * 2009-06-24 2012-11-13 Carl Zeiss Meditec Ag Microscopy system for eye surgery
BR112012001042A2 (pt) 2009-07-14 2016-11-22 Gen Hospital Corp equipamento e método de medição do fluxo de fluído dentro de estrutura anatômica.
BR122013021647A2 (pt) 2009-08-26 2016-04-05 Lumidigm Inc métodos de localização de objeto, de discriminação de objeto e de segundo plano, e, sistema
US8668636B2 (en) * 2009-09-30 2014-03-11 Fujifilm Corporation Electronic endoscope system, processor for electronic endoscope, and method of displaying vascular information
WO2011097508A2 (en) * 2010-02-04 2011-08-11 University Of Southern California Combined spectral and polarimetry imaging and diagnostics
EP2542145B1 (de) 2010-03-05 2020-08-12 The General Hospital Corporation Systeme zur bereitstellung mikroskopischer bilder von mindestens einer anatomischen struktur mit einer bestimmten auflösung
US8570149B2 (en) 2010-03-16 2013-10-29 Lumidigm, Inc. Biometric imaging using an optical adaptive interface
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
US9557154B2 (en) 2010-05-25 2017-01-31 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
EP2575598A2 (de) 2010-05-25 2013-04-10 The General Hospital Corporation Vorrichtungen, systeme, verfahren und computerlesbares medium zur spektralanalyse von bildern aus einer optischen kohärenz-tomographie
JP6066901B2 (ja) 2010-06-03 2017-01-25 ザ ジェネラル ホスピタル コーポレイション １つまたは複数の管腔器官内または管腔器官にある構造を撮像するための装置およびデバイスのための方法
JP2011257160A (ja) * 2010-06-04 2011-12-22 Canon Inc 光干渉断層撮像装置、光干渉断層撮像方法、およびプログラム
US9638632B2 (en) 2010-06-11 2017-05-02 Vanderbilt University Multiplexed interferometric detection system and method
SG188227A1 (en) 2010-08-16 2013-04-30 Cognoptix Inc System and method for detecting amyloid proteins
JP5384453B2 (ja) 2010-09-09 2014-01-08 シャープ株式会社 測定装置、測定システム、測定方法、制御プログラム、および、記録媒体
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
WO2012078636A1 (en) 2010-12-07 2012-06-14 University Of Iowa Research Foundation Optimal, user-friendly, object background separation
US9063074B2 (en) * 2010-12-30 2015-06-23 Empire Technology Development Llc Analyzing tissue morphology in three dimensions
WO2012100221A1 (en) 2011-01-20 2012-07-26 University Of Iowa Research Foundation Automated determination of arteriovenous ratio in images of blood vessels
GB2487940B (en) 2011-02-09 2014-12-17 Tel Hashomer Medical Res Infrastructure & Services Ltd Methods and devices suitable for imaging blood-containing tissue
US9562853B2 (en) 2011-02-22 2017-02-07 Vanderbilt University Nonaqueous backscattering interferometric methods
US9033510B2 (en) 2011-03-30 2015-05-19 Carl Zeiss Meditec, Inc. Systems and methods for efficiently obtaining measurements of the human eye using tracking
WO2012149175A1 (en) 2011-04-29 2012-11-01 The General Hospital Corporation Means for determining depth-resolved physical and/or optical properties of scattering media
WO2012170963A1 (en) * 2011-06-08 2012-12-13 Digital Light Innovations System and method for hyperspectral imaging
JP5623348B2 (ja) * 2011-07-06 2014-11-12 富士フイルム株式会社 内視鏡システム、内視鏡システムのプロセッサ装置、及び内視鏡システムの作動方法
WO2013004801A1 (en) 2011-07-07 2013-01-10 Carl Zeiss Meditec Ag Improved data acquisition methods for reduced motion artifacts and applications in oct angiography
JP2014523536A (ja) 2011-07-19 2014-09-11 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィーにおいて偏波モード分散補償を提供するためのシステム、方法、装置およびコンピュータアクセス可能な媒体
WO2013029047A1 (en) 2011-08-25 2013-02-28 The General Hospital Corporation Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures
WO2013066631A1 (en) 2011-10-18 2013-05-10 The General Hospital Corporation Apparatus and methods for producing and/or providing recirculating optical delay(s)
US9101294B2 (en) 2012-01-19 2015-08-11 Carl Zeiss Meditec, Inc. Systems and methods for enhanced accuracy in OCT imaging of the cornea
WO2013142366A1 (en) 2012-03-19 2013-09-26 Genetic Innovations, Inc. Devices, systems, and methods for virtual staining
EP2833776A4 (de) 2012-03-30 2015-12-09 Gen Hospital Corp Abbildungssystem, verfahren und distaler anschluss zur multidirektionalen sichtfeldendoskopie
WO2013165614A1 (en) 2012-05-04 2013-11-07 University Of Iowa Research Foundation Automated assessment of glaucoma loss from optical coherence tomography
US9273949B2 (en) 2012-05-11 2016-03-01 Vanderbilt University Backscattering interferometric methods
CA3088289A1 (en) 2012-05-18 2013-11-21 Rebellion Photonics, Inc. Divided-aperture infra-red spectral imaging system for chemical detection
US9599508B2 (en) 2012-05-18 2017-03-21 Rebellion Photonics, Inc. Divided-aperture infra-red spectral imaging system
US11490797B2 (en) 2012-05-21 2022-11-08 The General Hospital Corporation Apparatus, device and method for capsule microscopy
JP5576993B2 (ja) 2012-05-30 2014-08-20 パナソニック株式会社 画像計測装置、画像計測方法及び画像計測システム
JP6227652B2 (ja) 2012-08-22 2017-11-08 ザ ジェネラル ホスピタル コーポレイション ソフトリソグラフィを用いてミニチュア内視鏡を製作するためのシステム、方法、およびコンピュータ・アクセス可能媒体
JP6124548B2 (ja) 2012-10-17 2017-05-10 キヤノン株式会社 眼科撮影方法および眼科装置
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9039179B2 (en) 2012-12-11 2015-05-26 Elwha Llc Unobtrusive active eye interrogation
US9039180B2 (en) 2012-12-11 2015-05-26 Elwah LLC Self-aligning unobtrusive active eye interrogation
US9101297B2 (en) 2012-12-11 2015-08-11 Elwha Llc Time-based unobtrusive active eye interrogation
FR3000346B1 (fr) * 2012-12-21 2015-01-23 Thales Sa Procede et dispositif de correction de reponse spatiale pour spectrometres a transformee de fourier imageurs
EP3000382A1 (de) * 2012-12-28 2016-03-30 Canon Kabushiki Kaisha Bildverarbeitungsvorrichtung und bildverarbeitungsverfahren
WO2014120791A1 (en) 2013-01-29 2014-08-07 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
WO2014121082A1 (en) 2013-02-01 2014-08-07 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
US10478072B2 (en) 2013-03-15 2019-11-19 The General Hospital Corporation Methods and system for characterizing an object
WO2014143891A1 (en) 2013-03-15 2014-09-18 University Of Iowa Research Foundation Automated separation of binary overlapping trees
CA2911294C (en) 2013-05-03 2022-08-30 Tearscience, Inc. Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis
US9784681B2 (en) 2013-05-13 2017-10-10 The General Hospital Corporation System and method for efficient detection of the phase and amplitude of a periodic modulation associated with self-interfering fluorescence
EP3692887B1 (de) 2013-07-19 2024-03-06 The General Hospital Corporation Bildgebungsvorrichtung mithilfe von endoskopie mit multidirektionalem sichtfeld
EP3021735A4 (de) 2013-07-19 2017-04-19 The General Hospital Corporation Bestimmung der augenbewegung mittels netzhautabbildung mit rückkopplung
WO2015013651A2 (en) 2013-07-26 2015-01-29 The General Hospital Corporation System, apparatus and method utilizing optical dispersion for fourier-domain optical coherence tomography
US9562849B2 (en) 2013-11-12 2017-02-07 Rebellion Photonics, Inc. Divided-aperture infra-red spectral imaging system
US9733460B2 (en) 2014-01-08 2017-08-15 The General Hospital Corporation Method and apparatus for microscopic imaging
WO2015116986A2 (en) 2014-01-31 2015-08-06 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
US9211064B2 (en) 2014-02-11 2015-12-15 Welch Allyn, Inc. Fundus imaging system
US9237847B2 (en) 2014-02-11 2016-01-19 Welch Allyn, Inc. Ophthalmoscope device
WO2015143435A1 (en) 2014-03-21 2015-09-24 University Of Iowa Research Foundation Graph search using non-euclidean deformed graph
US10228556B2 (en) 2014-04-04 2019-03-12 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
US11290662B2 (en) 2014-05-01 2022-03-29 Rebellion Photonics, Inc. Mobile gas and chemical imaging camera
US9756263B2 (en) 2014-05-01 2017-09-05 Rebellion Photonics, Inc. Mobile gas and chemical imaging camera
WO2015183994A1 (en) * 2014-05-28 2015-12-03 Santec Corporation Non-invasive optical measurement of blood analyte
US10458905B2 (en) 2014-07-07 2019-10-29 Rebellion Photonics, Inc. Gas leak emission quantification with a gas cloud imager
ES2907287T3 (es) 2014-07-25 2022-04-22 Massachusetts Gen Hospital Aparato para imagenología y diagnóstico in vivo
EP3000395B1 (de) * 2014-09-19 2018-05-23 IMEC vzw System und verfahren zur überwachung des auges einer person
JP2018506715A (ja) 2015-01-23 2018-03-08 ヴァンダービルト ユニバーシティー 堅固なインターフェロメーター及びその使用方法
US10799115B2 (en) 2015-02-27 2020-10-13 Welch Allyn, Inc. Through focus retinal image capturing
US11045088B2 (en) 2015-02-27 2021-06-29 Welch Allyn, Inc. Through focus retinal image capturing
US10548520B2 (en) 2015-04-01 2020-02-04 Santec Corporation Non-invasive optical measurement of blood analyte
US10115194B2 (en) 2015-04-06 2018-10-30 IDx, LLC Systems and methods for feature detection in retinal images
EP4375631A2 (de) 2015-05-29 2024-05-29 Rebellion Photonics, Inc. Wasserstoffsulfid-abbildungssystem
JP6713149B2 (ja) 2015-06-01 2020-06-24 サンテック株式会社 ２つの波長を合成する光コヒーレンストモグラフィーシステム
US10136804B2 (en) 2015-07-24 2018-11-27 Welch Allyn, Inc. Automatic fundus image capture system
US10772495B2 (en) 2015-11-02 2020-09-15 Welch Allyn, Inc. Retinal image capturing
EP3190394A3 (de) * 2015-12-15 2017-11-15 Applied Spectral Imaging Ltd. System und verfahren zur spektralen bildgebung
US10413179B2 (en) 2016-01-07 2019-09-17 Welch Allyn, Inc. Infrared fundus imaging system
WO2017132483A1 (en) 2016-01-29 2017-08-03 Vanderbilt University Free-solution response function interferometry
GB201602068D0 (en) 2016-02-05 2016-03-23 Univ Bristol Measuring sensitivity to polarized light
EP3206061A1 (de) * 2016-02-15 2017-08-16 Leica Instruments (Singapore) Pte. Ltd. Beleuchtungsfiltersystem und beobachtungssystem für ein multispektrales fluoreszenzmikroskop
US10677580B2 (en) 2016-04-27 2020-06-09 Santec Corporation Optical coherence tomography system using polarization switching
US10602926B2 (en) 2016-09-29 2020-03-31 Welch Allyn, Inc. Through focus retinal image capturing
US10285589B2 (en) 2016-09-30 2019-05-14 Welch Allyn, Inc. Fundus image capture system
EP4212851A1 (de) 2016-10-21 2023-07-19 Rebellion Photonics, Inc. Gasabbildungssystem
CA3041105A1 (en) 2016-10-21 2018-04-26 Rebellion Photonics, Inc. Mobile gas and chemical imaging camera
DE112018000393T5 (de) * 2017-01-16 2019-09-26 Hoya Corporation Endoskopsystem und Bildanzeigevorrichtung
WO2018144633A1 (en) * 2017-01-31 2018-08-09 Theranos Ip Company, Llc Methods and devices for improved signal detection from biological samples
US10955355B2 (en) 2017-02-22 2021-03-23 Rebellion Photonics, Inc. Systems and methods for monitoring remote installations
WO2018200840A1 (en) 2017-04-27 2018-11-01 Retinopathy Answer Limited System and method for automated funduscopic image analysis
US10502546B2 (en) 2017-11-07 2019-12-10 Santec Corporation Systems and methods for variable-range fourier domain imaging
EP4379331A2 (de) 2017-11-09 2024-06-05 Rebellion Photonics, Inc. Fensterverdunkelungssensoren für mobile gas- und chemische bildgebungskameras
EP3716838A4 (de) 2017-11-27 2021-08-11 Retispec Inc. Von hyperspektralem bild geführter raman-okularbildgeber für pathologien von morbus alzheimer
WO2019164455A1 (en) * 2018-02-21 2019-08-29 Optotek D.O.O. Image-processing apparatus and image-processing method for detection of irregularities in tissue
US10582853B2 (en) 2018-03-13 2020-03-10 Welch Allyn, Inc. Selective illumination fundus imaging
US11213200B2 (en) 2018-03-22 2022-01-04 Santec Corporation Topographical imaging using combined sensing inputs
US11067671B2 (en) 2018-04-17 2021-07-20 Santec Corporation LIDAR sensing arrangements
US10838047B2 (en) 2018-04-17 2020-11-17 Santec Corporation Systems and methods for LIDAR scanning of an environment over a sweep of wavelengths
JP7484708B2 (ja) * 2018-04-18 2024-05-16 株式会社ニコン 画像処理方法、プログラム、及び画像処理装置
JP7279712B2 (ja) * 2018-04-18 2023-05-23 株式会社ニコン 画像処理方法、プログラム、及び画像処理装置
WO2019222616A1 (en) 2018-05-18 2019-11-21 Northwestern University Spectral contrast optical coherence tomography angiography
US11096574B2 (en) 2018-05-24 2021-08-24 Welch Allyn, Inc. Retinal image capturing
JPWO2021020466A1 (de) * 2019-07-30 2021-02-04
US11161109B2 (en) 2019-09-19 2021-11-02 Invidx Corp. Point-of-care testing cartridge with sliding cap
US11327084B2 (en) * 2019-09-19 2022-05-10 Invidx Corp. Joint hematology and biochemistry point-of-care testing system
WO2021072408A1 (en) * 2019-10-10 2021-04-15 Georgia Tech Research Corporation Label-free hematology and histopathology analysis using deep-ultraviolet microscopy
JP2023507929A (ja) * 2019-12-12 2023-02-28 ケムイメージ コーポレーション 組織ターゲットの区別のためのシステムおよび方法
CN112683899A (zh) * 2020-04-29 2021-04-20 海南远生渔业有限公司 一种水产品品质检测方法
WO2024057149A1 (en) * 2022-09-14 2024-03-21 Alcon Inc. Generation of multispectral imaging information using analytical multispectral imaging

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS598933A (ja) * 1982-07-07 1984-01-18 キヤノン株式会社 視標を具えた眼科機械
CH662261A5 (de) * 1983-09-19 1987-09-30 Yves Dr Med Robert Ophthalmologisches geraet fuer die untersuchung des augenhintergrundes und messvorrichtung fuer das geraet.
US4858124A (en) * 1984-08-15 1989-08-15 Riverside Research Institute Method for enhancement of ultrasonic image data
DD262797A1 (de) * 1987-08-03 1988-12-14 Zeiss Jena Veb Carl Untersuchungsgeraet und verfahren fuer das auge, insbesondere den augenhintergrund
US4922919A (en) 1988-03-22 1990-05-08 Duke University Method for measuring ocular oxidative metabolism
US5109276A (en) * 1988-05-27 1992-04-28 The University Of Connecticut Multi-dimensional multi-spectral imaging system
US4976542A (en) * 1988-07-25 1990-12-11 Washington University Digital array scanned interferometer
US5016173A (en) * 1989-04-13 1991-05-14 Vanguard Imaging Ltd. Apparatus and method for monitoring visually accessible surfaces of the body
GB8909491D0 (en) 1989-04-26 1989-06-14 Glynn Christopher J Device for real-time monitoring of human or animal bodily functions
FR2660182A1 (fr) 1990-03-27 1991-10-04 Ciposa Microtech Papillometre.
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US6198532B1 (en) * 1991-02-22 2001-03-06 Applied Spectral Imaging Ltd. Spectral bio-imaging of the eye
US5219400A (en) 1991-06-11 1993-06-15 The United States Of America As Represented By The Secretary Of The Army Noninvasive method for quantitation of oxyhemoglobin saturation by near-infrared reflectance spectrophotometry
US5400791A (en) 1991-10-11 1995-03-28 Candela Laser Corporation Infrared fundus video angiography system
US5303709A (en) * 1991-12-16 1994-04-19 Dreher Andreas W Retinal eye disease diagnostic system
US5377003A (en) * 1992-03-06 1994-12-27 The United States Of America As Represented By The Department Of Health And Human Services Spectroscopic imaging device employing imaging quality spectral filters
US5383467A (en) 1992-11-18 1995-01-24 Spectrascience, Inc. Guidewire catheter and apparatus for diagnostic imaging
EP0767361B1 (de) * 1993-07-22 2000-02-23 Applied Spectral Imaging Ltd. Verfahren und Vorrichtung zur Spektralen Bilderfassung
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
HU215614B (hu) * 1994-04-15 1999-09-28 Coloryte Hungary Optikai Kutató, Fejlesztő és Gyártó RT. Eljárás és berendezés szemben lévő színérzékelő receptorok spektrális érzékenységi paramétereinek meghatározására
US5485229A (en) 1994-05-24 1996-01-16 Allergan, Inc. Method and apparatus for determining electrical activity in the retinal nerve fiber layer using intrinsic birefringent properties of retinal ganglion cell axons
US5493109A (en) 1994-08-18 1996-02-20 Carl Zeiss, Inc. Optical coherence tomography assisted ophthalmologic surgical microscope

Also Published As

Publication number Publication date
EP1026987A4 (de) 2004-03-24
JP2001517521A (ja) 2001-10-09
EP1026987A1 (de) 2000-08-16
US6419361B2 (en) 2002-07-16
US6556853B1 (en) 2003-04-29
WO1999016353A1 (en) 1999-04-08
AU9592098A (en) 1999-04-23
US20010033364A1 (en) 2001-10-25
IL134152A0 (en) 2001-04-30
US6198532B1 (en) 2001-03-06

Similar Documents

Publication Publication Date Title
US6556853B1 (en) Spectral bio-imaging of the eye
US6276798B1 (en) Spectral bio-imaging of the eye
WO2000067635A1 (en) Spectral bio-imaging of the eye
US20020099295A1 (en) System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same
US5784162A (en) Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US8649008B2 (en) Combined spectral and polarimetry imaging and diagnostics
Keane et al. Retinal imaging in the twenty-first century: state of the art and future directions
US6088099A (en) Method for interferometer based spectral imaging of moving objects
US11253151B2 (en) Multispectral and hyperspectral ocular surface evaluator
Yoneya et al. Retinal oxygen saturation levels in patients with central retinal vein occlusion
Lemmens et al. Hyperspectral imaging and the retina: worth the wave?
Bittencourt et al. Blue light versus green light fundus autofluorescence in normal subjects and in patients with retinochoroidopathy secondary to retinal and uveitic diseases
Alabboud et al. New spectral imaging techniques for blood oximetry in the retina
JP3474883B2 (ja) 可動物の、干渉形に基づくスペクトル結像装置
Harvey et al. Hyperspectral imaging for the detection of retinal diseases
US20220390369A1 (en) Systems And Methods For Imaging And Characterizing Objects Including The Eye Using Non-Uniform Or Speckle Illumination Patterns
US20130225951A1 (en) Determination of oxygen saturation in a tissue of visual system
Di Cecilia et al. Hyperspectral imaging of the human iris
IL129842A (en) Method and apparatus for spectral bio-imaging of the eye
Alterini Hyperspectral imaging system for the fast recording of the ocular fundus
WO2002039873A2 (en) System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same
Dwight Snapshot Hyperspectral Imaging for Complete Fundus Oximetry
Atlan Doppler holography for ophthalmology
Soliz et al. Spectrally-based fundus imaging: implications for image enhancement and diagnosis of retinal diseases
Theelen Scanning laser imaging of the retina. Basic concepts and clinical applications

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed