IL134031A - Method for preparing the history of alkoxy furanone, compounds produced by this method and use of these compounds - Google Patents
Method for preparing the history of alkoxy furanone, compounds produced by this method and use of these compoundsInfo
- Publication number
- IL134031A IL134031A IL13403198A IL13403198A IL134031A IL 134031 A IL134031 A IL 134031A IL 13403198 A IL13403198 A IL 13403198A IL 13403198 A IL13403198 A IL 13403198A IL 134031 A IL134031 A IL 134031A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- acid
- compound
- cis
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9708932A FR2766188B1 (fr) | 1997-07-15 | 1997-07-15 | Nouveau procede de preparation de derives amines d'alkyloxy furanone, composes issus de ce procede et utilisation de ces composes |
| PCT/FR1998/001480 WO1999003852A1 (fr) | 1997-07-15 | 1998-07-09 | Procede de preparation de derives amines d'alkyloxyfuranone, composes issus de ce procede et utilisation de ces composes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL134031A0 IL134031A0 (en) | 2001-04-30 |
| IL134031A true IL134031A (en) | 2004-06-01 |
Family
ID=9509210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13403198A IL134031A (en) | 1997-07-15 | 1998-07-09 | Method for preparing the history of alkoxy furanone, compounds produced by this method and use of these compounds |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6235899B1 (hu) |
| EP (1) | EP0998470B1 (hu) |
| JP (1) | JP4450987B2 (hu) |
| KR (1) | KR100519691B1 (hu) |
| CN (1) | CN100363355C (hu) |
| AP (1) | AP1071A (hu) |
| AR (1) | AR015924A1 (hu) |
| AT (1) | ATE239713T1 (hu) |
| AU (1) | AU744272B2 (hu) |
| BG (1) | BG64050B1 (hu) |
| BR (1) | BR9810896A (hu) |
| CA (1) | CA2296742C (hu) |
| CZ (1) | CZ295312B6 (hu) |
| DE (1) | DE69814395T2 (hu) |
| DK (1) | DK0998470T3 (hu) |
| EA (1) | EA002883B1 (hu) |
| EE (1) | EE03873B1 (hu) |
| ES (1) | ES2197489T3 (hu) |
| FR (1) | FR2766188B1 (hu) |
| HR (1) | HRP20000027B1 (hu) |
| HU (1) | HU230148B1 (hu) |
| ID (1) | ID23784A (hu) |
| IL (1) | IL134031A (hu) |
| ME (1) | ME01708B (hu) |
| NO (1) | NO324508B1 (hu) |
| NZ (1) | NZ502338A (hu) |
| PL (1) | PL200820B1 (hu) |
| PT (1) | PT998470E (hu) |
| RS (1) | RS49832B (hu) |
| SK (1) | SK284168B6 (hu) |
| TR (1) | TR200000117T2 (hu) |
| UA (1) | UA66364C2 (hu) |
| WO (1) | WO1999003852A1 (hu) |
| ZA (1) | ZA986203B (hu) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7053056B2 (en) * | 1998-07-02 | 2006-05-30 | Idun Pharmaceuticals, Inc. | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
| ES2347133T3 (es) * | 2000-04-24 | 2010-10-26 | Vertex Pharmaceuticals Incorporated | Procedimiento e intermedios para preparar acetales de acido aspartico sustituidos. |
| PE20011350A1 (es) | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
| JP2003327568A (ja) * | 2000-09-20 | 2003-11-19 | Kanegafuchi Chem Ind Co Ltd | 光学活性β−アミノ酸誘導体の製造方法 |
| JPWO2002055478A1 (ja) * | 2001-01-16 | 2004-05-13 | 鐘淵化学工業株式会社 | 光学活性アミノラクトン誘導体の製造法およびその中間体 |
| AU2005219861B2 (en) | 2004-02-27 | 2011-08-11 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| KR101135765B1 (ko) | 2004-03-12 | 2012-04-23 | 버텍스 파마슈티칼스 인코포레이티드 | 아스파르트산 아세탈 카스파아제 억제제의 제조를 위한방법 및 중간체 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204261B1 (en) * | 1995-12-20 | 2001-03-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β Converting enzyme inhibitors |
| US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
-
1997
- 1997-07-15 FR FR9708932A patent/FR2766188B1/fr not_active Expired - Lifetime
-
1998
- 1998-07-09 US US09/463,014 patent/US6235899B1/en not_active Expired - Lifetime
- 1998-07-09 ES ES98937591T patent/ES2197489T3/es not_active Expired - Lifetime
- 1998-07-09 EA EA200000127A patent/EA002883B1/ru not_active IP Right Cessation
- 1998-07-09 KR KR10-2000-7000398A patent/KR100519691B1/ko not_active IP Right Cessation
- 1998-07-09 AU AU86333/98A patent/AU744272B2/en not_active Expired
- 1998-07-09 EP EP98937591A patent/EP0998470B1/fr not_active Expired - Lifetime
- 1998-07-09 CA CA002296742A patent/CA2296742C/fr not_active Expired - Lifetime
- 1998-07-09 NZ NZ502338A patent/NZ502338A/en not_active IP Right Cessation
- 1998-07-09 CN CNB98808967XA patent/CN100363355C/zh not_active Expired - Lifetime
- 1998-07-09 CZ CZ200065A patent/CZ295312B6/cs not_active IP Right Cessation
- 1998-07-09 WO PCT/FR1998/001480 patent/WO1999003852A1/fr active IP Right Grant
- 1998-07-09 ID IDW20000067A patent/ID23784A/id unknown
- 1998-07-09 DK DK98937591T patent/DK0998470T3/da active
- 1998-07-09 BR BR9810896-4A patent/BR9810896A/pt not_active Application Discontinuation
- 1998-07-09 HU HU0003857A patent/HU230148B1/hu unknown
- 1998-07-09 TR TR2000/00117T patent/TR200000117T2/xx unknown
- 1998-07-09 PL PL338035A patent/PL200820B1/pl unknown
- 1998-07-09 AP APAP/P/2000/001732A patent/AP1071A/en active
- 1998-07-09 JP JP2000503076A patent/JP4450987B2/ja not_active Expired - Lifetime
- 1998-07-09 IL IL13403198A patent/IL134031A/en not_active IP Right Cessation
- 1998-07-09 EE EEP200000024A patent/EE03873B1/xx unknown
- 1998-07-09 DE DE69814395T patent/DE69814395T2/de not_active Expired - Lifetime
- 1998-07-09 ME MEP-2000-15A patent/ME01708B/me unknown
- 1998-07-09 SK SK30-2000A patent/SK284168B6/sk not_active IP Right Cessation
- 1998-07-09 PT PT98937591T patent/PT998470E/pt unknown
- 1998-07-09 RS YUP-15/00A patent/RS49832B/sr unknown
- 1998-07-09 AT AT98937591T patent/ATE239713T1/de active
- 1998-07-13 ZA ZA9806203A patent/ZA986203B/xx unknown
- 1998-07-15 AR ARP980103455A patent/AR015924A1/es not_active Application Discontinuation
- 1998-09-07 UA UA2000020800A patent/UA66364C2/uk unknown
-
2000
- 2000-01-12 BG BG104073A patent/BG64050B1/bg unknown
- 2000-01-14 NO NO20000182A patent/NO324508B1/no not_active IP Right Cessation
- 2000-01-14 HR HR20000027A patent/HRP20000027B1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |